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Contact Name
Megan Asri Humaira
Contact Email
publikasiilmiah@unida.ac.id
Phone
+6281314039779
Journal Mail Official
ijar@unida.ac.id
Editorial Address
Universitas Djuanda Jl. Tol Jagorawi No.1, Ciawi, Kec. Ciawi, Bogor, Jawa Barat 16720 Website: http://journal.unida.ac.id/index.php/IJAR/index Email: ijar@unida.ac.id
Location
Kota bogor,
Jawa barat
INDONESIA
Indonesian Journal of Applied Research (IJAR)
ISSN : -     EISSN : 27226395     DOI : https://doi.org/10.30997/ijar.v1i3
Indonesian Journal of Applied Research (IJAR), e-ISSN 2722-6395 is high quality open access peer reviewed research journal that is published by Universitas Djuanda (UNIDA). IJAR dedicated to publish significant research findings in the field of Applied Sciences, Engineering &Technology. We welcome original empirical research articles with novel perspectives and/or methodological approaches that would appeal to an international readership. We do not accept unsolicited conceptual and theoretical papers. The journal is designed to serve researchers, developers, professionals, graduate students and others interested in state-of-the art research activities in Applied Sciences, which covers four (2) majors areas of research that includes Applied Sciences, Engineering &Technology. The journal was first published in April 2020 and published every April, August and December.
Articles 132 Documents
Optimization of Multigrain Beverage Formulas: The Effect of Cereals and Legumes on Physical Characteristics Mulyaningtias, Irena Dwi; Faridah, Didah Nur; Muhandri, Tjahja
Indonesian Journal of Applied Research (IJAR) Vol. 7 No. 1 (2026): Indonesian Journal of Applied Research (IJAR)
Publisher : Universitas Djuanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30997/ijar.v7i1.859

Abstract

Multigrain beverages were ready-to-drink products that were easy to consume at any time and contained high levels of soluble fiber, vegetable protein, unsaturated fatty acids, vitamin B complex, and phenolic compounds. Multigrain beverages were generally made from cereals and nuts. One problem associated with multigrain drinks was sedimentation and phase separation. The stability of the resulting drink depended on the type of raw material used. Therefore, this study aimed to optimize the processing of the physical characteristics of multigrain drinks. This study used Response Surface Methodology (RSM) with a D-optimal mixture design involving concentration factors of sweet corn (10–20%), red beans (20–30%), green beans (15–25%), black rice (10–20%), and sorghum (15–25%). The physical characteristics analyzed included viscosity, turbidity, suspension stability, and total solids. The results showed that a composition consisting of sweet corn at 19.75%, red beans at 20%, green beans at 25%, black rice at 10.25%, and sorghum at 25% yielded a desirability value of 0.816, with a viscosity of 63.4 mPa·s, turbidity of 115.4 ntu, suspension stability of 0.86%, and total solids of 9.11%, providing the optimum formula for producing high-quality multigrain drinks with high physical stability.
Docking-Based Evaluation of LC–HRMS Metabolites from Fermented Mustard Greens on DNA Gyrase B and Xanthine Oxidase Nasri; Cintya, Henni; Silalahi, Jansen; Haro, Ginda; Suci, Nurul; Kaban, Vera Estefania
Indonesian Journal of Applied Research (IJAR) Vol. 7 No. 1 (2026): Indonesian Journal of Applied Research (IJAR)
Publisher : Universitas Djuanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30997/ijar.v7i1.866

Abstract

Fermented mustard greens (Brassica juncea L. Czern.) contain bioactive metabolites formed through lactic acid bacteria–driven biotransformation, yet their molecular targets related to antibacterial and antioxidant functions remain poorly understood. This study aimed to characterize key metabolites in fermented mustard greens and evaluated their potential inhibitory activity against DNA gyrase B and Xanthine Oxidase through an integrated LC–HRMS metabolomics and molecular docking approach. Untargeted LC–HRMS profiling identified 292 metabolite features, from which five compounds—gentisic acid, trans-cinnamic acid, xanthurenic acid, indole-3-lactic acid, and indole-3-acrylic acid—were structurally confirmed via MS/MS fragmentation. These metabolites were docked against DNA gyrase B (5D7R) and Xanthine Oxidase (3NVW) to predict binding affinity and interaction mechanisms. Xanthurenic acid exhibited the strongest interaction with DNA gyrase B (–7.6 kcal/mol), forming hydrogen bonds with key catalytic residues, such as Asp81 and Ile86, which suggested ATP-competitive inhibition. Meanwhile, gentisic acid and indole-3-acrylic acid exhibited the most favorable binding to Xanthine Oxidase (–7.2 kcal/mol), characterized by π–π stacking with Phe914 and Phe1009 and hydrogen bonding to Glu802, indicating dual antioxidant and anti-hyperuricemic potential. These findings highlighted fermented mustard greens as a promising functional food source containing metabolites with predicted antibacterial and XO-inhibitory activities. Further in vitro and in vivo validation is required to confirm these computational insights.