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Jurnal Buana Farma
Published by Universitas Buana Perjuangan Karawang
ISSN : -     EISSN : 27972100     DOI : 10.36805
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
The major focus of Jurnal Buana Farma is to publish articles in the area of Experimental Pharmacology, Clinical Pharmacy, Pharmaceutical Technology, Pharmacoeconomy, Pharmacognosy, Pharmaceutical chemistry.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 14 Documents
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Search results for , issue "Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi" : 14 Documents clear
Literatur Review Artikel : MANFAAT PENGUJIAN AMILUM DAN PROTEIN PADA LARUTAN GLUKOSA, PATI (UJI MOLISCH) DENGAN MENGGUNAKAN BERBAGAI METODE Fikayuniar, Lia; Putri, Nurhaliza; Candra, Ayu; Susanto, Nabila Tsabitah; Rahayu, Mega Septiani; Azalia, Riza Khaila; Azizah, Sella Siti Nur
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1085

Abstract

The testing of starch and protein in glucose and starch solutions was conducted using the Molisch test and other methods. Glucose, as a monosaccharide, serves as the main energy source, while starch, being a polysaccharide, must first be broken down into monosaccharides before it can be utilized. Carbohydrates, such as glucose and starch, provide energy and support food metabolism and characteristics such as taste, color, and texture. The methods applied in this review include literature studies on the chemical testing of starch and protein, focusing on the Molisch test for detecting carbohydrates in biological samples. Various approaches, including color-change-based methods and other analytical techniques, were used to measure starch and protein in glucose and starch solutions. The review findings highlight the importance of a thorough understanding of starch characteristics and its modification to enhance its utility in the food and pharmaceutical sectors. These findings support the use of pregelatinized starch and the exploration of alternative carbohydrates sources to improve food quality and variety. Qualitative tests, such as Benedict's, detect reducing sugars in foods, while temperature increases affect the moisture content and compaction of starch, especially in pregelatinized cassava starch. In conclusion, starch testing methods like iodine and Molisch tests are effective for analyzing starch and carbohydrates, while the ratio of starch to water and temperature play key roles in influencing the physical properties of starch.
REVIEW: INSTRUMEN KUESIONER PADA PASIEN DIABETES MELITUS Putra , Erwin Ekadharma; Hermanto, Faizal; Sukandar, Elin Yulinah
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1113

Abstract

Diabetes mellitus (DM) is a chronic disease with increasing prevalence worldwide, posing major challenges in patient management and monitoring. Questionnaire instruments are an important tool in DM patient evaluation because they allow systematic and measurable data collection regarding various aspects of the disease, including quality of life, self-management, and perceptions of care. This review article provides a comprehensive overview of various questionnaire instruments used for DM patient evaluation, interpretation of questionnaire results, and grouping based on categories. The review results indicate that the selection of an appropriate instrument must take into account the specific context of the patient population and the evaluation goals. Additionally, we group the evaluation instruments into several categories, including the patient's level of knowledge, compliance with treatment, severity of symptoms, fear of needles, mental condition, and improvement in the patient's quality of life. The conclusion of this article emphasizes the importance of questionnaires in DM management, as well as the need for further research to develop more comprehensive and responsive instruments. Questionnaire instruments, when selected and used appropriately, can improve clinical decision-making and the quality of care provided to DM patients.
FORMULASI DAN UJI FISIK SALEP KOMBINASI EKSTRAK PUTRI MALU (Mimosa Pudica) DAN DAUN JARAK PAGAR (Jatropha Curcas) Enjelina, Sinta Mei; Pambudi, Risma Sakti; Ramadhani, Mutia; Subiyanto, Abyasa Fajari; Ilmi, Ibnul; Rahmadin, Mega Tri
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1114

Abstract

Indonesia is a tropical country that has the potential to experience skin diseases. The development of drugs from natural ingredients can be used to treat skin diseases. One of the appropriate pharmaceutical preparations for treating skin infections is ointment. Putri Malu (Mimosa Pudica) and Jatropha Leaves (Jatropha Cuscas) are plants that contain flavonoids, alkaloids, saponins, tannins and phenols which have the potential to inhibit bacterial growth. The aim of this research is to formulate an ointment preparation from the extract of putrimalu (mimosa pudica) and jatropha curcas leaves (jatropha curcas) which meets the requirements of an ointment preparation by means of a physical test of the ointment. This type of research was experimental, which was carried out by making 3 ointment formulations combining Putri Malu and Jatropha leaves using the ointment base Vasellin Album and Adeps Lanae. Physically tested ointment preparations include organoleptic tests, homogeneity tests, pH tests, viscosity tests, spreadability tests, and adhesiveness tests. Based on testing of a combination of ointment preparations from the extract of putrimalu (mimosa pudica) and jatropha leaves (jatrooha cuscas) with a base of vasellin album and adeps lanae, the organoleptic results were blackish brown, distinctive odor, semi-solid consistency, homogeneous ointment with a Ph value of 5 and viscosity test. adhesion and spreading power in accordance with ointment preparation standards. The best formulation of the ointment combination of the extract of the mollusk (mimosa pudica) and jatropha curcas (jatropha cusrcas) leaves is formulation 2 with a ratio of (2:2).
KAJIAN RASIONALITAS PENGGUNAAN ANTIBIOTIK PADA ANAK DENGAN INFEKSI SALURAN KEMIH DI RSUD Dr. MOEWARDI SURAKARTA Agustiningrum, Frisda Ayu; Amrullah, Adhi Wardhana; Rahardjoputro, Rolando
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1118

Abstract

Urinary tract infection (UTI) is the second highest infectious disease among children in Indonesia. Management of UTI requires antibiotic therapy, but the irrational use of antibiotics makes this disease one of the contributors to the high rate of antibiotic resistance. Therefore, there is a need for a study to measure the rationality of antibiotic use in children with UTI. This study is a descriptive observational study with a cross sectional design. Data were collected retrospectively using a purposive sampling technique based on medical record data of pediatric patients at Dr. Moewardi Surakarta Hospital in 2021-2023. The results showed that out of 100 medical records of pediatric patients with UTI, 68.00% were women and 32.00% were men. Based on age, the highest incidence of UTI occurred in the age range of 10-18 years as much as 52.00%. The most common antibiotic use was ampicillin 68.00%. The results of the rationality study showed 69.00% in category 0 (rational use of antibiotics). Irrationality occurred in category IIA (antibiotic use is not the right dose) 17.00%, IIIA (antibiotic use with too long duration) 1.00%, IIIB (antibiotic use with too short duration) 4.00%, IIA & IIIB (antibiotic use is not the right dose & duration is too short) 2.00%, IVA (there are other more effective antibiotic options) 4.00%, IIIB & IVA (antibiotic use is too short duration & there are other more effective antibiotic options) 3.00%. It can be concluded that the rational use of antibiotics needs to be improved.
EVALUASI PENGGUNAAN TERAPI OBAT KARDIOVASKULAR PADA PASIEN HIPERTENSI YANG DIRAWAT DI RSUP DR. M. DJAMIL PADANG Marsellinda, Elsa; Aulia, Dhea Suci
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1121

Abstract

Hypertension is one of the major modifiable risk factors associated with cardiovascular disease, and its prevalence and severity increase with age. The purpose of this study was to look at the description of the use of hypertension drug therapy, gender and age level of patients treated at dr. M. Djamil Padang Hospital October-December 2023 period. Data were collected retrospectively from the medical records of hypertensive patients admitted to the internal medicine ward. period October to December 2023 analyzed descriptively. Based on the results of the study of 131 hypertensive patients who were treated at DR. M.Djamil Padang Hospital in the October-December 2023 period, it was concluded that male sex patients were more than female, based on the age of patients with an age range of 56 - 65 years and the use of the most widely used antihypertensive therapy was 3 combinations.
KAJIAN INTERAKSI OBAT PASIEN DIABETES DI BEBERAPA RUMAH SAKIT DI INDONESIA Aeni, Siti Nur; Sukandar, Elin Yulinah; Hermanto, Faizal
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1123

Abstract

Lebih dari 451 juta orang di seluruh dunia pada tahun 2017 diperkirakan menderita diabetes, suatu kelainan metabolik yang umum, dan diperkirakan akan meningkat menjadi 693 juta orang pada tahun 2045, atau 49,7% dari populasi orang dewasa (IDF Diabetes Atlas). Diabetes merupakan penyakit kronis yang seringkali memerlukan penggunaan kombinasi obat-obatan, sehingga meningkatkan risiko terjadinya interaksi obat. Tujuan dari penelitian ini adalah untuk menganalisis kemungkinan terjadinya interaksi obat potensial pada pasien diabetes melitus yang pernah berkunjung ke beberapa rumah sakit di Indonesia antara tahun 2014 dan 2024. Penelusuran pustaka dilakukan pada basis data Google Scholar, Pubmed dan jurnal-jurnal lainnya. Kriteria inklusi untuk publikasi artikel yang dipublikasikan selama dekade terakhir, artikel yang dipilih harus mengamati kasus-kasus interaksi obat pada pasien diabetes di rumah sakit. Penelusuran pustaka menghasilkan 10 jurnal yang relevan dan memenuhi kriteria. Hasil penelitian menyajikan potensi interaksi obat diabetes dengan berbagai obat lain berdasarkan mekanisme kerja, efek yang ditimbulkan, klasifikasi dan tingkat keparahan serta solusi yang ditampilkan. Obat diabetes yang paling banyak digunakan adalah Glimepirid dari golongan sulfonil urea. Studi interaksi obat sebagian besar bekerja secara farmakodinamik dengan tingkat keparahan sedang. Pentingnya pemantauan dan pengelolaan interaksi obat untuk meningkatkan efektivitas pengobatan dan keamanan pasien diabetes
ANALISIS KADAR ALKALOID DAN FLAVONOID SEDUHAN RAMBUT JAGUNG (Zea mays L. ) DENGAN METODE SPEKTROFOTOMETRI UV-VIS Al Azzahra, Yunita; Hidayat, Taufik Septiyan; Dewi, Lisna; Saepudin, Syumillah; Kartikawati, Endah; Rahayu, Iseu; Ajeng, Nurtina Dwi; Widiyaningrum, Eva Mutba
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1126

Abstract

Corn silk is generally a waste of sweet corn plants after being harvested and is rarely used, however, on the other hand, corn silk is also used by the community as herbal medicine and is believed to reduce the risk of hypertension and other types of chronic diseases such as kidney infections. Corn silk is thought to contain metabolite compounds such as flavonoids, essential oils, steroids, and alkaloids. Alkaloid compounds can function as drugs and strong activators for immune cells that can destroy bacteria, viruses, fungi, and cancer cells. Flavonoid compounds are compounds that have various bioactive effects such as anti-inflammatory, antiviral, cardioprotective, anti-diabetic, anti-cancer, anti-aging, and antioxidants. it is necessary to measure the levels of alkaloids and flavonoids from corn silk infusion to determine the levels of alkaloid and flavonoid compounds in corn silk infusion. The method used in this study is the Uv-Vis spectrophotometry method. The alkaloid content was calculated using the regression formula y = 0.0895x - 0.3046, the results obtained in the corn hair infusion extract were 46.36 mg / g extract, and the flavonoid content was calculated using the regression formula y = 0.0144 x - 0.025 and the results obtained in the corn hair infusion extract were 85.42 mg / g extract. So it can be concluded that corn hair infusion contains more flavonoid compounds, namely with alkaloid compound levels of 46.36 mg / g extract and flavonoid compounds of 85.42 mg / g extract.
EVALUASI PENGGUNAAN OBAT ANTITUBERKULOSIS PARU DIPUSKESMAS: NARRATIVE LITERATURE REVIEW Rohendiputri, Isyaura Bellafasya; Wahyuningsih, Sri
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1127

Abstract

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. While it primarily affects the lungs, it can also impact other organs. In Indonesia, pulmonary TB remains a significant health issue. This study aims to evaluate the use of anti-tuberculosis medications at various community health centers (puskesmas) in Indonesia through a literature review. The research method employed involves a literature review with searches conducted on Google Scholar and PubMed databases. Out of 360 articles found on Google Scholar and 13,026 articles on PubMed, 8 relevant articles were identified for this study. The results indicate that the most commonly used treatment regimen is Category 1, which includes a 2-month intensive phase with a combination of Isoniazid 75 mg, Rifampicin 150 mg, Pyrazinamide 400 mg, and Ethambutol 275 mg, followed by a 4-month continuation phase with Rifampicin 150 mg and Isoniazid 150 mg. This medication regimen aligns with the Tuberculosis Control Guidelines issued by the Indonesian Ministry of Health in 2016. The evaluation shows that Indonesian puskesmas generally adhere to the established treatment guidelines but still require further monitoring to ensure adherence and effectiveness of the treatment.
A KAJIAN POTENSI INTERAKSI OBAT PADA PASIEN GERIATRI DENGAN GAGAL JANTUNG DI RSUD Dr. MOEWARDI SURAKARTA TAHUN 2023 Safira, Della Anggun; Amrullah, Adhi Wardhana; Rahardjoputro, Rolando
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1129

Abstract

Geriatric patients with heart failure generally receive more than 1 type of drug therapy, called polypharmacy, which typically involves at least four types of treatment: ACEI (Angiotensin Converting Enzyme Inhibitors), diuretics, beta blockers, and digoxin. This causes an increase in the occurrence of drug interactions. This study aims to determine the potential drug interactions that occur in geriatric patients with heart failure who undergo hospitalization at Dr. Moewardi Surakarta Hospital from January to December 2023. This study is a descriptive observational study with a cross-sectional design, and the data were collected retrospectively using a purposive sampling technique based on the medical records of geriatric patients at Dr. Moewardi Surakarta Hospital in 2023. The inclusion criteria were inpatients aged ≥55 years who were diagnosed with heart failure. The exclusion criteria were patients with incomplete or illegible medical record data or who died during treatment. Drug interaction research was conducted based on Drugs.com and Medscape. The results showed that out of the 100 patients, 98 experienced drug interactions. The incidence of drug interactions was 252 minor cases (21.65%), 818 moderate cases (69.50%), and 106 major cases (9.00%). The mechanism of drug interaction was pharmacodynamic in 919 cases (65.50%), pharmacokinetic in 213 cases (30.40%), and unknown in 44 cases (4.10%).
PENGARUH KONSELING APOTEKER TERHADAP KEPATUHAN TERAPI PASIEN DIABETES MELITUS DI BEBERAPA PUSKESMAS DAN RUMAH SAKIT Putri, Mareta Ananda; Sukandar, Elin Yulinah
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1130

Abstract

Diabetes mellitus is a global health issue that requires a comprehensive management approach. Pharmacist interventions have proven effective in enhancing patient adherence to medication and improving clinical outcomes. This study aims to systematically review pharmacist interventions for diabetes mellitus patients and their impact on medication adherence and glycemic control. The research method used was a narrative literature review, analyzing 188 articles from PubMed and 200 articles from Google Scholar, with 20 studies meeting the inclusion criteria, including 12 studies conducted in community health centers (puskesmas) and 8 studies in hospitals. The findings indicate that pharmacist counseling interventions significantly improve medication adherence and lower HbA1c levels. In community health centers, adherence increased from 9.2% to 61%, and HbA1c decreased from 8.5% to 7.2%. In hospitals, the average HbA1c reduction was between 1.5% and 2%. The multifaceted counseling approach was more effective compared to telephone counseling, which showed an HbA1c reduction of 0.3%. These findings highlight the critical role of pharmacists in managing type 2 diabetes mellitus.

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