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Jurnal Buana Farma
Published by Universitas Buana Perjuangan Karawang
ISSN : -     EISSN : 27972100     DOI : 10.36805
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
The major focus of Jurnal Buana Farma is to publish articles in the area of Experimental Pharmacology, Clinical Pharmacy, Pharmaceutical Technology, Pharmacoeconomy, Pharmacognosy, Pharmaceutical chemistry.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 18 Documents
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Search results for , issue "Vol. 5 No. 1 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi" : 18 Documents clear
TINJAUAN SISTEMATIS PENGELOLAAN OBAT DI BERBAGAI FASILITAS KESEHATAN INDONESIA: SEBUAH REVIEW ARTIKEL Nusantara, Julius; Sutjiatmo, Afifah B
Jurnal Buana Farma Vol. 5 No. 1 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i1.1250

Abstract

This study aims to analyze drug management in various healthcare facilities in Indonesia, including hospitals, primary healthcare centers (puskesmas), and other health institutions. The primary focus is on the implementation of policies and drug management practices, as well as the role of healthcare professionals, particularly pharmacists, in ensuring drug availability in accordance with the National Formulary and pharmaceutical service standards. This study employs a review article approach with a descriptive-analytic method and qualitative analysis, reviewing 40 relevant journals obtained from databases such as PubMed, Google Scholar, and Sinta. The findings indicate that 90% of the reviewed journals report suboptimal drug management, with major challenges including drug unavailability, price fluctuations, and weaknesses in drug management systems. Therefore, this study recommends enhancing training for healthcare professionals, optimizing resource allocation, and developing a more efficient drug management information system to improve drug availability and efficiency in Indonesian healthcare facilities.
EFEK ANTIMIKROBA EKSTRAK Arcangelisia flava, Curcuma longa, Curcuma zanthorrhiza TERHADAP Bacillus DAN Pseudomonas PENYEBAB DIARE Hujjastusnani, Noor; Amin, Astuti muh.; Nirmalasari, Ridha; Awaluddin, Annisa Maharani; Latifah, Nadia Dwi Nur; Riana, Rifa; Nisa, Khairun`; Ningsih, Ira Wahyu; Anisa, Nor
Jurnal Buana Farma Vol. 5 No. 1 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i1.1256

Abstract

Diarrhea is a major health issue often caused by Bacillus sp. and Pseudomonas aeruginosa. This study aims to evaluate the antibacterial activity of a combination of Arcangelisia flava, Curcuma longa, and Curcuma zanthorrhiza extracts against these bacteria. The research was conducted in vitro using a Completely Randomized Design (CRD) with extract concentrations of 30%, 50%, 75%, and 100%, along with positive and negative controls. Antibacterial tests were carried out using the disk diffusion method to measure the inhibition zones after 24, 48, and 72 hours of incubation. The results showed the highest inhibition zones at 100% concentration, reaching 1.38 mm for Bacillus sp. and 1.33 mm for Pseudomonas aeruginosa after 72 hours. This antibacterial activity is supported by active compounds such as flavonoids, alkaloids, and curcumin. In conclusion the combination of these extracts effectively inhibits diarrhea-causing bacteria and has potential as a safe herbal alternative to address antibiotic resistance.
UJI AKTIVITAS ANTIOKSIDAN RUMPUT JUKUT PENDUL (Kyllinga nemoralis) Nabila, Regina Syifa; Soemarie, Yulistia Budianti; Ramadhani, Juwita
Jurnal Buana Farma Vol. 5 No. 1 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i1.1267

Abstract

Antioxidants are compounds that play an important role in preventing the impact of free radicals that cause various degenerative diseases. Synthesized antioxidants have carcinogenic properties over a long period of time, hence the need for natural sources of antioxidants that have fewer side effects. Jukut pendul grass (Kyllinga nemoralis) is one of the wild plants that has potential as a natural antioxidant. This study aims to compare the antioxidant activity of ethanol extract, n-hexane fraction, ethyl acetate fraction, and water fraction of jukut pendul grass (Kyllinga nemoralis). The steps of this research were samples of jukut pendul grass (Kyllinga nemoralis) obtained from Kota Baru, South Kalimantan in maceration with 70% ethanol then fractionated using 3 solvents of different polarity. Antioxidant activity testing was performed with a Uv-Vis spectrophotometer using the DPPH method at a wavelength of 515 nm. The results showed that the IC50 value of ethanol extract was 79,842 + 14,275 µg/mL, n-hexane fraction 95,632 + 8,152 µg/mL, ethyl acetate fraction 42,616 + 1,972 µg/mL and water fraction 67,384 + 11,678 µg/mL. Based on the IC50 value, jukut pendul grass (Kyllinga nemoralis) has antioxidant activity with the highest activity in the ethyl acetate fraction.
PENGARUH KONSENTRASI BEESWAX SEBAGAI EMULGATOR PADA KARAKTERISTIK DAN STABILITAS FISIK SEDIAAN KRIM PATI BENGKUANG (Pachyrhizus erosus L.) Puspitasari, Dewi Fitriani; Ratih, Sekar Wida
Jurnal Buana Farma Vol. 5 No. 1 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i1.1290

Abstract

Starch of bengkuang tuber (Pachyrhizus erosus L.) has antioxidant activity, is able to provide moisture, antiaging , relieve inflammation so that it is efficacious to prevent skin cell damage due to free radicals. The formulation of bengkuang starch in cream form is expected to make it easier to use. The main component that affects the physical characteristics of a cream preparation is the emulgator. Beeswax is an emulgator that can improve cream consistency and stabilise the preparation. This study aims to determine the effect of different concentrations of beeswax on the physical characteristics and stability of bengkuang starch cream preparation. The research method begins with the collection of starch which is done by filtering the juice of the bengkuang tuber. The results of the filter were precipitated 24 hours and then the precipitate was dried. The cream was made in 3 formulas namely FI, FII and FIII with variations of beeswax 5, 10 and 15%, then tested for characteristics and physical stability. The results showed that increasing the concentration of beeswax caused the viscosity value of the cream preparation to increase, the spreadability value decreased and the adhesion value increased. The concentration of beeswax also affects the pH value of the preparation, namely the higher the concentration of beeswax, the pH value increases. The results of the physical stability test using the cycling test method for 6 cycles show that the cream preparations that are still stable are formula II and III.
RIVIEW : TINGKAT PENGETAHUAN DAN FAKTOR YANG MEMPENGARUHI KEPATUHAN MINUM OBAT ARV iman, Sudirman; Wahyuningsih, Sri
Jurnal Buana Farma Vol. 5 No. 1 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i1.1292

Abstract

This review article aims to determine the level of knowledge & factors that influence compliance with taking antiretroviral (ARV) drugs in HIV patients. Human Immunodeficiency Virus (HIV) is a health problem that requires special & serious attention throughout the world.. With the high prevalence of HIV/AIDS, a good underst&ing of ARV treatment is crucial for enhancing patients' quality of life. The research method employs a literature review analyzing 15 articles from various relevant scientific sources. The results indicate a significant relationship between patients' knowledge levels & their adherence to ARV therapy. Factors such as education level, social support, availability of information, & societal stigma significantly impact adherence. Non-adherence to treatment can lead to drug resistance, making continuous education & support from healthcare providers essential. Recommendations for improving adherence include enhancing patient knowledge & providing social support. Thus, it is hoped that adherence to ARV medication can improve, contributing to better health outcomes for HIV/AIDS patients.
REVIEW: KEPATUHAN PENGGUNAAN OBAT ANTIHIPERTENSI PADA PASIEN HIPERTENSI DIBEBERAPA RUMAH SAKIT DAN PUSKESMAS DI INDONESIA Ardiansyah, Muhamad; Sukandar, Elin Yulinah
Jurnal Buana Farma Vol. 5 No. 1 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i1.1294

Abstract

Hipertensi merupakan penyakit yang umum ditemukan dalam kehidupan sehari-hari dan merupakan salah satu penyebab kematian di seluruh dunia. Komplikasi hipertensi dapat mengenai berbagai organ target, seperti jantung, otak, ginjal dan mata. Kerusakan organ tersebut bergantung pada tingginya tekanan darah pasien dan berapa lama tekanan darah tinggi tersebut tidak terkontrol dan tidak diobati. Artikel review ini bertujuan untuk mengidentifikasi tingkat kepatuhan minum obat antihipertensi pada pasien hipertensi dibeberapa Rumah Sakit dan Puskesmas di Indonesia. Metode yang digunakan adalah naratif literatur review melalui penelusuran 15 artikel dengan tahun penerbitan 2015-2024. Penelusuran literatur dilakukan pada database Google Scholar, PubMed, Research Gate dan ScienceDirect. Kata kunci yang digunakan pada penulusuran yaitu Antihipertensi, dan Medication adherence. Hasil tinjauan literatur ini menunjukan bahwa masih sangat rendah tingkat kepatuhan penggunaan obat antihipertensi pada beberapa Rumah Sakit dan Puskesmas yang ada di Indonesia dari 15 artikel yang dianalisis kepatuhan pasien hipertensi dibeberapa rumah sakit bervariasi dengan rata-rata kepatuhan tinggi 25,38%, kepatuhan sedang 27,14% dan kepatuhan rendah 49,50%, kepatuhan pasien hipertensi dibeberapa puskesmas dengan rata-rata kepatuhan tinggi 23%, kepatuhan sedang 31% dan kepatuhan rendah 46,6%. Kesimpulannya masih sangat banyak pasien hipertensi yang tidak patuh dalam minum obat, kepatuhan minum obat merupakan faktor utama keberhasilan terapi hipertensi. Untuk meningkatkan kepatuhan minum obat pasien hipertensi diperlukan peran penting Apoteker untuk mengintervensi, monitoring, dan juga meningkatkan pengetahuan pasien hipertensi guna tercapainya tekanan darah yang stabil
LITERATURE REVIEW: POTENSI FRAKSINASI PROPOLIS LEBAH KELULUT SEBAGAI PENELUSURAN AGEN ANTIDIABETES Sarah, Aulia; Kustiawan, Paula Mariana
Jurnal Buana Farma Vol. 5 No. 1 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i1.1295

Abstract

Diabetes mellitus is a metabolic disorder characterised by hyperglycaemia caused by abnormalities in insulin secretion and insulin action. Indications that arise in people with diabetes include polyuria, hyperphagia and polydipsia. Propolis or bee glue is a product made from plant sources by bees. This study aims to recognise the potential of propolis as an antidiabetic agent in diabetes mellitus. The research method in the literature study by applying journal searches on Google Scholar, PubMed, and ResearchGate databases published in 2010-2024. Based on the results of the article search, 7 suitable journals were identified. These articles consisted of 7 experimental articles. The results showed that propolis can be used as an effective antidiabetic agent to control blood glucose levels, repair damage to the islets of Langerhans, suppress oxidative stress and as an anti-inflammatory. Active compounds contained in kelulut bee propolis such as flavonoids and also other compounds such as phenolics, polyphenols and caffeic acid phenethyl ester (CAPE) compounds. It is also known that propolis treatment can reduce diabetic complications such as nephropathy, retinopathy, leg ulcers, and liver disease. propolis has great potential as a natural antidiabetic drug. The secondary metabolites in propolis, such as flavonoids, terpenoids and saponins, provide various properties including protecting pancreatic β-cells, reducing insulin resistance, and reducing oxidative stress. Fractionation can be one method of exploring the potential of propolis as an antidiabetic.
REVIEW: EVALUASI RASIONALITAS PENGGUNAAN OBAT ANTIHIPERTENSI DI BEBERAPA RUMAH SAKIT DI INDONESIA Gusdilla, Windy; Hermanto, Faizal
Jurnal Buana Farma Vol. 5 No. 1 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i1.1298

Abstract

Approximately 1 billion people, or about a quarter of the world's adult population, are estimated to suffer from hypertension, and this number continues to grow. By 2025, the number of people with hypertension is predicted to reach 1.6 billion. Inaccuracy in the use of drugs can lead to increased morbidity and mortality, especially in patients with chronic diseases. Therefore, the selection of drugs must always follow the established treatment standards. This review article aims to evaluate the rationality of the use of antihypertensive drugs in several hospitals in Indonesia. The method used is a narrative literature review through a search of 11 articles with publication years 2019-2024. Literature searches were conducted on the Google Scholar, PubMed, and ScienceDirect databases. The keywords used in the search are "Antihypertension and "Rationality". The results of the literature review indicate that the use of antihypertensive drugs in the hospital has been rational based on accurate diagnosis, accurate indication, accurate drug selection, accurate dosage, accurate method of administering drugs, accurate interval of administration, accurate duration of administration, and accurate assessment of patient conditions in accordance with existing therapy guidelines. Evaluation of the rationality of the use of antihypertensive drugs shows that the practice of this treatment in several hospitals in Indonesia is in accordance with the established standards, the use of antihypertensive drugs in the hospital is quite effective and safe for patients.
MENGIDENTIFIKASI KEPATUHAN MINUM OBAT PADA PASIEN DIABETES MELITUS TIPE 2 DI BERBAGAI PUSKESMAS DI INDONESIA Efadri, Yoky; Sutjiatmo, Afifah B.
Jurnal Buana Farma Vol. 5 No. 1 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i1.1300

Abstract

Diabetes mellitus is a chronic disease that sufferers suffer from throughout their lives and is a global problem. Non-compliance in taking medication in diabetes mellitus patients worsens the quality of life of patients. This article aims to identify the level of medication compliance in patients with diabetes mellitus. The method used in this article is a narrative literature review through a search of the PubMed, Google Scholar, and ScienceDirect. By identifying related articles, 1258 articles were obtained. Filtered based on inclusion criteria and 20 articles met the criteria. The results of the study showed low compliance in taking medication in patients with diabetes mellitus. Based on the article search, the lowest level of medication compliance was 94.4%. To improve compliance in taking medication in patients with diabetes mellitus, an important role of pharmacists is needed to intervene, monitor, and also increase knowledge of patients with diabetes mellitus in order to achieve stable glucose levels.
REVIEW : PENGARUH KONSELING APOTEKER TERHADAP KEPATUHAN TERAPI PASIEN HIPERTENSI DI BEBERAPA RUMAH SAKIT DI INDONESIA Anggraini, Villia; Wahyuningsih, Sri
Jurnal Buana Farma Vol. 5 No. 1 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i1.1305

Abstract

Hypertension is one of the chronic diseases that requires long-term treatment. Adherence to medication is key to controlling hypertension. Pharmacist counseling can play an important role in improving patient adherence to medication. This study aims to analyze the influence of pharmacist counseling on therapy adherence and therapy outcomes in hypertensive patients through a literature review. The method used is a literature review approach. The literature search was conducted through Google Scholar and PubMed with a publication year range of 2014-2024. The selected articles must meet the inclusion and exclusion criteria. Out of the 424 articles found, 10 articles were selected for further analysis. The analysis results show that pharmacist counseling improves patient adherence to hypertension treatment. Studies show that counseling can lower patients' blood pressure, increase their knowledge, and improve their behavior during therapy. The effectiveness of counseling is also influenced by the patient's education. Pharmacist counseling helps lower blood pressure and improve adherence in hypertensive patients. Therefore, in the treatment of hypertension, pharmacist counseling should be used to improve the quality of life of patients and reduce the risk of hypertension complications.

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