cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Farhamzah
Contact Email
farhamzah@ubpkarawang.ac.id
Phone
+6281380007942
Journal Mail Official
buanafarma@ubpkarawang.ac.id
Editorial Address
JL. H.S. Ronggowaluyo Telukjambe Timur Karawang 41361
Location
Kab. karawang,
Jawa barat
INDONESIA
Jurnal Buana Farma
Published by Universitas Buana Perjuangan Karawang
ISSN : -     EISSN : 27972100     DOI : 10.36805
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
The major focus of Jurnal Buana Farma is to publish articles in the area of Experimental Pharmacology, Clinical Pharmacy, Pharmaceutical Technology, Pharmacoeconomy, Pharmacognosy, Pharmaceutical chemistry.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 253 Documents
 22   23   24   25   26 
FORMULASI DAN EVALUASI SEDIAAN LIPSTIK MENGGUNAKAN PEWARNA ALAMI DARI EKSTRAK ETANOL BUAH BIT (Beta vulgaris L.) Artanti, Elsan Fitri; Ginting, Astriani Natalia Br.; Kaban, Vera Estefania
Jurnal Buana Farma Vol 6 No 1 (2026): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v6i1.1665

Abstract

Lip color is a cosmetic preparation used to color the lips with an artistic touch, thereby enhancing facial aesthetics in makeup application. Long-term use of lipstick containing synthetic dyes such as Rhodamine B may cause cancer and impair liver and kidney function. One plant that can serve as a natural coloring source is beetroot (Beta vulgaris L.), which contains betalain pigments classified as antioxidants. This study aimed to determine whether ethanol extract of beetroot can be formulated into a lipstick preparation as a natural colorant. This experimental research was conducted through several stages, including plant identification, collection, simplicia preparation, characterization, extraction using 70% ethanol, thin-layer chromatography (TLC) analysis, formulation, and evaluation of product quality. The evaluation included organoleptic testing, homogeneity, pH, melting point, hardness, spreadability, irritation test, hedonic test, and stability test. The TLC results showed that ethanol extract of beetroot was positive for flavonoids, alkaloids, tannins, saponins, and steroids. Lipstick formulations containing 15%, 20%, and 25% ethanol extract of beetroot were semi-solid with brown and dark brown colors, homogeneous, and had pH values within the Indonesian National Standard (SNI) range of 4.5–7.0. The melting points ranged from 50–63°C. The spreadability was glossy and evenly distributed, the hardness met SNI requirements, and the formulations did not cause irritation. Formula F3 was most preferred by the panelists, and all formulations remained stable during storage at 4°C and 40°C. In conclusion, the ethanol extract of beetroot can be formulated into a lipstick preparation as a natural colorant and demonstrates good physical quality.
FORMULASI SEDIAAN HAND BODY GEL DENGAN SARI BUAH RAMBUTAN (Nephelium lappaceum L.) Azizah, Nailan; Simanjuntak, Nerly Juli Pranita; Bangar, Roy Indrianto
Jurnal Buana Farma Vol 6 No 1 (2026): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v6i1.1673

Abstract

Rambutan fruit (Nephelium lappaceum L.) contains vitamins A, B, and C, which act as antioxidants and are beneficial for skin health. The utilization of rambutan fruit juice in a hand body gel formulation aims to produce a natural moisturizing product that is safe for use. This study was conducted experimentally by formulating rambutan fruit juice into hand body gel at concentrations of 3%, 5%, and 7%, along with a blank formulation. Each formulation was evaluated for its physical properties, including organoleptic characteristics, homogeneity, pH, spreadability, and viscosity. In addition, skin irritation testing and skin moisture testing using a skin analyzer were performed over three weeks of use. The results showed that all formulations had good physical quality, pH values suitable for the skin, and did not cause irritation. Skin moisture testing indicated an increase in skin moisture in all formulations, with the 7% concentration showing the highest improvement. In conclusion, rambutan fruit juice can be formulated into a hand body gel that is safe and effective as a skin moisturizer, with the 7% concentration being the best formulation.
REVIEW: KETERSEDIAAN OBAT INDIKATOR DAN DISPARITAS WILAYAH PADA UPTD FARMASI DINAS KESEHATAN DI INDONESIA Rahmahwati, Dora Dewi; Hermanto, Faizal
Jurnal Buana Farma Vol 6 No 1 (2026): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v6i1.1675

Abstract

Drug availability is one of the main indicators of the quality of health services in Indonesia. Effective drug planning and distribution in the Regional Technical Implementation Unit (UPTD) of the Health Office Pharmacy is key to ensuring public access to essential drugs. This review aims to evaluate drug planning and distribution indicators in the UPTD Pharmacy of Health Offices throughout Indonesia based on recent published studies. A narrative review was conducted through a systematic search of academic databases for the period 2024-2025. Inclusion criteria included studies that evaluated drug planning, distribution, and availability in Indonesian health facilities. Data extracted included study location, study design, sample size, drug availability rate, planning accuracy, and stock-out rate. Of the 12 studies analyzed, drug availability rates varied between 78.5% and 95.2%, with an average of 87.5%. Medicine planning accuracy ranged from 75.2% to 98.5%. Stock-out rates showed significant variation between 4.1% and 22.1%, with an average of 13.7%. The study in Medan with the implementation of Distribution Requirement Planning showed the best results with 95.2% availability and 98.5% planning accuracy. Eastern Indonesia, such as Keerom and East Sumba, showed lower performance with availability below 85%. There are significant disparities in drug planning and distribution between regions in Indonesia. The implementation of integrated information systems and data-based planning methods such as Distribution Requirement Planning can improve drug availability and reduce stockouts. Special attention is needed in remote and eastern regions of Indonesia to improve access to essential drugs.
EVALUASI PENGGUNAAN OBAT PADA PASIEN DISPEPSIA MENGGUNAKAN METODE ATC/DDD DI RUMAH SAKIT ROYAL PRIMA TAHUN 2022 Hutabarat, Rachel Epifanes; Harahap, Daimah Wirdatus Sananun; Ginting, Astriani Natalia Br
Jurnal Buana Farma Vol 6 No 1 (2026): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v6i1.1677

Abstract

Dyspepsia is a common non-communicable disease that requires pharmacotherapy management according to clinical guidelines. Evaluation of drug use can be conducted using the ATC/DDD (Anatomical Therapeutic Chemical/Defined Daily Dose) and DU90% (Drug Utilization 90%) methods to describe prescribing patterns in healthcare facilities. This study aimed to evaluate drug use in dyspepsia patients at Royal Prima Hospital Medan in 2022 using a retrospective descriptive design using medical records of 180 patients from January–December 2022. Drugs were classified based on the WHO 2023 ATC system and analyzed using DDD calculations and the DU90% method. The results showed that four drugs included in the DU90% segment were omeprazole (tablets and injections) and ranitidine (tablets and injections), with a total contribution of 90.4% of the total DDD. The pattern of drug use is dominated by proton pump inhibitors and H₂ receptor antagonists, which are the main therapies in the management of dyspepsia based on the 2022 National Consensus on the Management of Dyspepsia and Helicobacter pylori Infection, so that the distribution of drug use obtained in this study shows compliance with national therapy recommendations.
UJI AKTIVITAS EKSTRAK ETANOL DAUN SIRIH CINA (PEPEROMIA PELLUCIDA L.) TERHADAP BAKTERI PSEUDOMONAS AERUGINOSA DAN PROPIONIBACTERIUM ACNES Sinaga, Helsi Herdiani; Ginting, Astriani Natalia br; Simanjuntak, Nerly Juli Pranita
Jurnal Buana Farma Vol 6 No 1 (2026): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v6i1.1678

Abstract

The Chinese betel leaf plant (Peperomia pellucida L.), a herbal plant belonging to the Piperaceae family, has antibiotic properties against the growth of acne-causing bacteria. The Chinese betel leaf plant is also known to have antibacterial activity. This study aimed to determine the antibacterial activity of the ethanol extract of Chinese betel leaf against Pseudomonas aeruginosa and Propionibacterium acnes. The method used was disc diffusion with varying concentrations of 10%, 20%, and 30%. Inhibition zone data were analyzed using a One-Way ANOVA test. The results showed that the ethanol extract of Chinese betel leaf was able to inhibit the growth of both bacteria and there was a significant difference between extract concentrations (p < 0.05). The ethanol extract of Chinese betel leaf has the potential as a natural antibacterial.
EFEKTIVITAS DAN IMPLEMENTASI REJIMEN BERBASIS DOLUTEGRAVIR PADA PASIEN HIV DI INDONESIA: TINJAUAN TERHADAP OUTCOME KLINIS DAN TANTANGAN PELAYANAN Hermanto, Faizal; Octora Dewi, Sylvia
Jurnal Buana Farma Vol 6 No 1 (2026): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v6i1.1679

Abstract

Dolutegravir-based regimens, including TLD (Tenofovir-Lamivudine-Dolutegravir), have become the first-line therapy recommended by WHO for HIV treatment. Indonesia has adopted this regimen in accordance with the Minister of Health Regulation No. 23/2022. This review analyzes the clinical effectiveness and implementation of dolutegravir-based regimens in HIV patients based on data from various health facilities in Indonesia. The purpose of this review article is to analyze the clinical outcomes of dolutegravir-based regimens, including viral load suppression, quality of life, and patient adherence. This review was conducted through a comprehensive search in the PubMed and Google Scholar databases for the period 2015-2025. The search query included the keywords “TLD regimen”, “dolutegravir”, “HIV”, “viral load suppression”, “Indonesia”, “clinical effectiveness”, “tenofovir”, and “lamivudine”. Articles were selected based on studies conducted in Indonesian healthcare facilities, involving adult HIV patients receiving dolutegravir-based regimens, and reporting clinical outcomes or program implementation. Six articles met the inclusion criteria and were analyzed. Results showed that dolutegravir-based regimens have good clinical outcomes in various health facilities in Indonesia. Studies in Palembang demonstrated high viral load suppression among patients receiving antiretroviral therapy. Multi-center studies showed significant improvement in quality of life after switching from nevirapine-based to dolutegravir-based regimens. Studies at the primary care level underscored the importance of medication adherence and adequate monitoring. The review concluded that dolutegravir-based regimens demonstrated good clinical effectiveness with diverse outcomes in HIV patients in Indonesia. Implementation requires strengthening viral load monitoring, adherence management, and capacity building at the primary care level.
SYSTEMATIC REVIEW RASIONALITAS ANTIHIPERTENSI PADA PREEKLAMSIA DI BEBERAPA RUMAH SAKIT DI INDONESIA MENGGUNAKAN PENDEKATAN PRISMA Nurfauziah, Yastin; Hermanto, Faizal
Jurnal Buana Farma Vol 6 No 1 (2026): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v6i1.1681

Abstract

Globally, preeclampsia is one of the main contributors to maternal mortality. In Indonesia, discrepancies between clinical practice and guideline recommendations for antihypertensive use in preeclampsia cases remain relatively high, potentially increasing risks for both mothers and fetuses. This study is a PRISMA-based systematic review that aims to evaluate the rational use of antihypertensive drugs in preeclampsia patients across various hospitals in Indonesia. A literature search was conducted in PubMed and Google Scholar for the period 2015–2025, identifying 76 articles, of which 11 met the inclusion and exclusion criteria. Most studies assessed three parameters of rationality—appropriate drug, appropriate indication, and appropriate dose—with mean adherence rates of 92.55%, 91.69%, and 86.73%, respectively. Nifedipine was the most commonly used first-line agent, while methyldopa was frequently used as an alternative or in combination; however, several hospitals still reported the use of drugs that are not recommended, such as candesartan. Variations in practice were mainly related to limited availability of first-line drugs and inconsistent implementation of dosing protocols, as reflected by one hospital where dose appropriateness reached only 5.3%. Overall, the use of antihypertensive therapy for preeclampsia in Indonesia is generally in line with existing guidelines; nevertheless, equitable access to essential medicines and ongoing training for healthcare workers are still needed to address therapy discrepancies arising from resource limitations.
UJI AKTIVITAS ANTIOKSIDAN TERHADAP DAUN BAKUNG (CRINUM ASIATICUM L.) DENGAN PELARUT ETANOL DENGAN METODE DPPH (2,2-DHIPHENYL-1-PIRCYLHYDRAZYL) Louisa, Natasya; Ginting, Astriani Natalia Br; Simanjuntak, Nerly July Pranita; Simbolon, Marlina L
Jurnal Buana Farma Vol 6 No 1 (2026): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v6i1.1682

Abstract

Free radicals are one of the main factors causing oxidative stress, which contributes to various degenerative diseases. Natural antioxidants derived from plants have the potential to serve as safer alternatives to synthetic antioxidants. One plant with potential as a natural antioxidant source is bakung (Crinum asiaticum L.), which has long been traditionally used, although scientific studies on it remain limited. This study aimed to determine the antioxidant activity of the ethanol extract of bakung leaves (Crinum asiaticum L.) using the DPPH method and to examine its secondary metabolite profile. This experimental research employed maceration extraction using 96% ethanol, followed by phytochemical screening to identify classes of compounds and antioxidant activity testing using the DPPH method expressed as IC₅₀ values. The results showed that the ethanol extract of bakung leaves contains alkaloids, flavonoids, tannins, saponins, and triterpenoids/steroids. The antioxidant activity test indicated that the extract exhibited strong antioxidant activity with an IC₅₀ value of 13.73 µg/mL, although it was still lower than vitamin C as the positive control, which had an IC₅₀ value of 8.56 µg/mL. Based on these findings, it can be concluded that the ethanol extract of bakung leaves (Crinum asiaticum L.) has potential as a natural antioxidant source and holds promise for further development in the fields of pharmacy and natural product chemistry.
FORMULASI DAN UJI AKTIVITAS SEDIAAN KRIM DARI EKSTRAK DAUN JAMBU BIJI (PSIDIUM GUAJAVA L.) SEBAGAI PENGOBATAN LUKA DIABETES Hieronima Vivin Triana Sinaga
Jurnal Buana Farma Vol 6 No 1 (2026): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v6i1.1683

Abstract

Introduction: Bacterial infections, especially Staphylococcus aureus, often accompany diabetic wounds, which are chronic consequences of diabetes mellitus. These infections slow the healing process and raise the risk of further problems. As a safe and useful supportive therapy, topical formulations based on natural ingredients must be developed. Objective: To formulate a cream preparation with an ethanolic extract of guava leaves (Psidium guajava L.) and assess its physical characteristics and antimicrobial efficacy against Staphylococcus aureus. Methods: 96% ethanol was used to macerate the extract, which was then screened for bioactive compounds utilizing phytochemicals. An oil-in-water (O/W) basis was used to create the cream in three extract concentrations (10%, 20%, and 30%). Organoleptic characteristics, homogeneity, pH, and spreadability tests were among the physical assessments. Antibacterial activity was assessed using the disc diffusion method. Results: Phytochemical screening confirmed the presence of flavonoids, tannins, saponins, and steroids. All cream formulations met the physical quality requirements for topical application. Both the extract and cream exhibited strong antibacterial activity against Staphylococcus aureus. Conclusion: The guava leaf ethanolic extract cream shows potential as a supportive topical therapy for controlling infections in diabetic wounds; however, further studies are required to evaluate long-term stability, broader antibacterial spectrum, and in vivo effectiveness.
UJI EFEKTIVITAS FORMULASI SEDIAAN SALEP FRAKSI ETIL ASETAT DAUN KOPASANDA (Chromoleana odorata L.) TERHADAP PENYEMBUHAN LUKA SAYAT PADA TIKUS JANTAN WISTAR (Rattus norvegicus) Nurasni; Neswita, Elfia; A’la, Nurul
Jurnal Buana Farma Vol 6 No 1 (2026): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v6i1.1687

Abstract

This study aimed to test the effectiveness of an ointment made from the ethyl acetate fraction of cotton apple (Chromoleana odorata L.) leaves in accelerating the healing of cut wounds in male white mice. Empirically, cotton apple leaves have long been used as a traditional medicine to treat wounds and infections. The objectives of this study were to assess the healing time, determine the most effective concentration, and compare the effectiveness of the ethyl acetate fraction ointment with a commercially available product. This was a laboratory experimental study with a post-test only control group design. Ointment formulations were prepared in three extract concentrations: FI (5%), FII (10%), and FIII (15%), each containing 1 gram, 2 grams, and 3 grams, respectively, and included positive and negative control groups. Effectiveness testing was conducted on experimental animals, comparing all treatment groups. Observed parameters included erythema, edema, and wound closure, measured by wound length using a ruler. The results showed that the FI formulation with a 10% concentration provided the fastest healing time, with wounds healing on average on the 10th day. Statistical analysis using ANOVA test (p < 0.005) showed that the ointment preparation of ethyl acetate fraction of cottonwood leaves was effective in accelerating the healing of cuts. Tukey's further test showed a significant difference between FI with KTP, KE, K-, FII, and FIII, but there was no significant difference between FII and povidone iodine ointment.

Page 25 of 26 | Total Record : 253

 22   23   24   25   26 

Filter by Year

2021 2026


Reset
Filter By Issues
All Issue Vol 6 No 1 (2026): Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 5 No. 2 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 5 No. 1 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 4 No. 2 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 4 No. 1 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 3 No. 4 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 3 No. 3 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 3 No. 2 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 3 No. 1 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 2 No. 4 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 2 No. 3 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 2 No. 2 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 2 No. 1 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 1 No. 4 (2021): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 1 No. 3 (2021): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 1 No. 2 (2021): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 1 No. 1 (2021): Jurnal Buana Farma : Jurnal Ilmiah Farmasi More Issue