cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Farhamzah
Contact Email
farhamzah@ubpkarawang.ac.id
Phone
+6281380007942
Journal Mail Official
buanafarma@ubpkarawang.ac.id
Editorial Address
JL. H.S. Ronggowaluyo Telukjambe Timur Karawang 41361
Location
Kab. karawang,
Jawa barat
INDONESIA
Jurnal Buana Farma
Published by Universitas Buana Perjuangan Karawang
ISSN : -     EISSN : 27972100     DOI : 10.36805
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
The major focus of Jurnal Buana Farma is to publish articles in the area of Experimental Pharmacology, Clinical Pharmacy, Pharmaceutical Technology, Pharmacoeconomy, Pharmacognosy, Pharmaceutical chemistry.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 226 Documents
 19   20   21   22   23 
PENGARUH KONSENTRASI EKSTRAK WORTEL (Daucus carota L.) DALAM FORMULASI LOTION TERHADAP EFEKTIVITAS PENCERAHAN KULIT Fitri, Ely Nurul; Nawangsari, Desy; Kurniasih, Khamdiyah Indah
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1527

Abstract

Carrot (Daucus carota L.) is a natural source rich in β-carotene, an antioxidant compound that may inhibit melanin formation through the tyrosinase inhibition mechanism. This study aimed to determine the effect of varying concentrations of carrot extract in lotion formulations on skin-brightening effectiveness. This experimental laboratory study used four lotion formulations: a negative control, Formula 1 (5%), Formula 2 (10%), Formula 3 (15%), and a positive control (Kojie San® commercial lotion). The formulations were evaluated for physical characteristics (organoleptic, homogeneity, pH, spreadability, adhesion, and viscosity), safety through skin irritation testing, and skin-brightening effectiveness using a human skin tone set for 14 days on 25 female respondents. The results showed that all formulations met the physical property parameters, except for spreadability and adhesion, which were below the standard. No skin irritation was observed. Based on the skin-brightening test, 16% of respondents showed an improvement in skin brightness after 14 days of application, with Formula 3 (15%) exhibiting the highest effect, where 8% of respondents experienced a one-level increase on the skin tone scale compared to other formulations and the negative control. It can be concluded that the variation in carrot extract concentration affected the skin-brightening effectiveness, with the 15% formulation showing the highest result. These findings indicate that β-carotene in carrot extract has potential as a safe and effective natural active ingredient in cosmetic skin-lightening formulations.
HUBUNGAN TINGKAT PENGETAHUAN DENGAN KEPATUHAN MINUM OBAT DAN LUARAN KLINIS PASIEN HIPERTENSI DI PUSKESMAS SETU 1 KABUPATEN BEKASI TAHUN 2025 Putri, Intan Auliya; Marselina, Marselina; Dewi, Masita Sari; Adiwisastra, Nuzul Gyanata
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1534

Abstract

Hypertension is a non-communicable disease that is a major health problem in Indonesia, especially in industrial areas such as Bekasi Regency. Patient knowledge of hypertension affects adherence to treatment and the success of therapy as measured by clinical outcomes in the form of blood pressure achievement. This study aims to determine the relationship between the level of knowledge with medication adherence and clinical outcomes in hypertensive patients at the Setu 1 Community Health Center in Bekasi Regency. This study used a quantitative design with a cross-sectional approach, involving 91 respondents selected using a purposive sampling technique. The instruments used included the HK-LS questionnaire to assess knowledge, the MMAS-8 for adherence, and medical record data for clinical outcomes. The analysis results showed a significant relationship between the level of knowledge with medication adherence (p = 0.009) and clinical outcomes of blood pressure (p = 0.003). It can be concluded that the higher the patient's level of knowledge, the higher the adherence to treatment and the success of achieving target blood pressure.
HUBUNGAN EFIKASI DIRI DAN KEPATUHAN PADA PASIEN HIPERTENSI DI RSUD KARAWANG Arfania, Maya; Nuraeni, Eni; Frianto, Dedy; Amal, Andi Nurzakiah; Fatmala, Widya; Nurhapit, Evi Riszka; Alfarizzy, Ali
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1536

Abstract

Medication adherence can affect patient health, one of the factors that can influence medication adherence in patients is self-efficacy. Self-efficacy has a positive relationship, so it is very important for hypertensive patients to maintain their treatment. Self-efficacy is very important for hypertensive patients during their treatment because it has a positive relationship. This study aims to determine how the influence of self-efficacy on medication adherence in hypertensive patients at Karawang Regional Hospital using a cross-sectional method based on a questionnaire (Medication Adherence Rating Scale). The questionnaire data (Medication Adherence Rating Scale) medication adherence and self-efficacy were analyzed using the chi-square test method which can determine the influence and relationship between medication adherence and self-efficacy. Based on the research that has been done, self-efficacy in hypertensive patients at Karawang Regional Hospital with a good self-efficacy level of 72.8%, with compliant compliance of 63.7% and non-compliant patients of 36.3%. There is no significant relationship between self-efficacy and adherence in hypertensive patients at Karawang Regional Hospital.
TINGKAT PENGETAHUAN DAN KEPATUHAN TERHADAP KUALITAS HIDUP PASIEN TUBERKULOSIS DI PUSKESMAS CIKARANG Damayanti, Nanda; Dewi, Masita Sari; Adiwisastra, Nuzul Gyanata; Rosiana, Rosiana
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1542

Abstract

Tuberculosis (TB) remains a major public health problem in Indonesia, including Bekasi Regency, which has a high disease burden. A decline in quality of life is commonly experienced by TB patients due to clinical symptoms, social stigma, and adverse drug effects. Although patient knowledge and treatment adherence are widely believed to influence therapeutic outcomes, evidence regarding their impact on quality of life remains inconsistent and limited, particularly in the Cikarang region. This study aimed to examine the relationship between knowledge level and treatment adherence with the quality of life of pulmonary tuberculosis patients at Puskesmas Cikarang Utara. A cross-sectional design was employed involving 93 outpatient pulmonary TB patients who met the inclusion criteria, including age 17–65 years, undergoing category I/II therapy, able to communicate, and willing to participate, as well as exclusion criteria of having significant comorbid conditions. Participants were selected using purposive sampling. Data were collected using a structured knowledge questionnaire, the Morisky Medication Adherence Scale (MMAS-8), and the Short Form-36 (SF-36). Statistical analysis was performed using the Chi-Square test. The majority of respondents demonstrated good knowledge (86%), moderate to high treatment adherence (86%), and a high quality of life (55.9%). Chi-Square analysis indicated no significant association between knowledge level and quality of life (p = 0.468), nor between treatment adherence and quality of life (p = 0.962). These findings suggest that knowledge and adherence alone are insufficient determinants of quality of life among pulmonary TB patients. Therefore, improving patients’ quality of life requires comprehensive interventions. Beyond treatment adherence.
PERAN AMILITE GCK-12H SEBAGAI SURFAKTAN PADA FORMULA SHAMPO: KAJIAN STABILITAS BUSA DAN EFEKTIVITAS PEMBERSIHAN Yuniarsih, Nia; Gunarti, Neni Sri; Mursal, Iin Lidia Putama; Angeline, Tiara Maharani; Abriyani, Ermi
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1543

Abstract

Shampoo functions to clean hair and scalp and is generally formulated using Sodium Lauryl Sulfate (SLS) surfactants, which are associated with irritation and unstable foam. Surfactant selection is therefore a critical factor in shampoo formulation, as it influences foam production, softness, hair moisture retention, environmental friendliness, and cleansing effectiveness. Amino acid–based surfactants such as Amilite GCK-12H offer advantages including low irritation potential, good foam stability, and biocompatibility. This study aimed to evaluate the effect of Amilite GCK-12H concentration on cleaning power and foam stability in shampoo formulations. The study was conducted by formulating shampoos and performing accelerated stability testing, including pH, viscosity, organoleptic properties, spreadability, homogeneity, foam stability, and cleaning effectiveness. Four formulations were prepared: F0 without Amilite GCK-12H, F1 containing 5%, F2 containing 10%, and F3 containing 15% Amilite GCK-12H. Organoleptic evaluation showed stable odor and homogeneity in all formulations, although color changes occurred in samples exposed to sunlight. pH testing indicated that all formulations remained within the acceptable range of 5.0–9.0, despite slight decreases under certain storage conditions. Viscosity increased at room temperature but decreased at elevated temperatures. Homogeneity and spreadability tests met standard requirements for shampoo preparations. Formulation F3 demonstrated the best performance in foam stability and cleaning effectiveness, achieving a cleaning efficiency of 62% on day 30. Overall, Amilite GCK-12H proved effective in producing a stable shampoo formulation with improved foam characteristics and cleansing performance. These findings support its potential application as a mild, high-performance surfactant for sustainable cosmetic shampoo development in future industrial formulations globally.
POTENSI FRAKSI DAUN SIRIH MERAH (Piper crocatum) MENGHAMBAT JAMUR PENYEBAB KEPUTIHAN Puspitasari, Dewi Fitriani; Kresnawati, Yani; Sebtiana K, Rika
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1547

Abstract

Vaginal discharge is a condition suffered by many women, both adolescents and menopausal women. This is due to hormonal changes and imbalances in normal flora, as well as fungal infections such as Candida albicans. Several studies have tested the activity of red betel leaf fractions against Candida albicans using 70% and 80% ethanol solvents in the extraction process. This study aims to test the activity of n-hexane and ethyl acetate fractions of red betel leaf against Candida albicans extracted using 96% ethanol solvent. The study began with extraction using 96% ethanol solvent, followed by phytochemical screening of the extract. Fractionation was carried out with n-hexane, ethyl acetate, and water solvents. The n-hexane and ethyl acetate fractions were then tested for their activity against Candida albicans. The results showed that the n-hexane fraction exhibited greater inhibitory activity against Candida albicans than the ethyl acetate fraction (p<0.05), indicating that the n-hexane fraction is more potent in inhibiting Candida albicans.
HUBUNGAN TINGKAT PENGETAHUAN DAN KEPATUHAN DENGAN KEBERHASILAN PENGOBATAN PASIEN TUBERKULOSIS DI PUSKESMAS TELAGA MURNI, CIKARANG Salamah, Hanifah Ikka; Dewi, Masita Sari; Adiwisastra, Nuzul Gyanata; Marselina, Marselina
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1549

Abstract

Tuberculosis (TB) remains a public health problem in Indonesia, with treatment success rates that have not yet reached national targets, partly influenced by patient behavioral factors. Patient knowledge and medication adherence are considered important determinants of TB treatment outcomes. This study aimed to analyze the relationship between patients’ knowledge level and medication adherence with tuberculosis treatment success at Telaga Murni Community Health Center, West Cikarang District. This quantitative study employed a correlational analytical design using a cross-sectional approach. The study sample consisted of 80 adult pulmonary TB patients selected through total sampling. Data were collected through structured interviews using a knowledge questionnaire and the Morisky Medication Adherence Scale-8 (MMAS-8), as well as medical record reviews to assess treatment success. Data were analyzed using univariate and bivariate analysis with the Chi-square test. The majority of respondents were female (58.7%), aged 17–25 years (35%), had senior high school education (50%), and were unemployed (51.2%). Most respondents received treatment observer (PMO) assistance (58.8%), were in the advanced treatment phase (58.7%), and were classified under treatment category I (97.5%). Good knowledge levels were identified in 90% of respondents, while low medication adherence was observed in 85%. Treatment success was achieved in 12.5% of respondents. Chi-square analysis showed no statistically significant relationship between knowledge level and treatment success (p = 0.827), nor between medication adherence and treatment success (p = 0.365). In conclusion, patient knowledge level and medication adherence were not significantly associated with tuberculosis treatment success, suggesting the need for broader multidisciplinary intervention strategies.
AKTIVITAS ANTIOKSIDAN EKSTRAK KASAR DAN EKSTRAK TERPURIFIKASI DAUN KELOR (Moringa oleifera) DENGAN METODE DPPH Pertiwi, Krisna Kharisma; Imulda, Asih; Hesturini, Rosa J; Juliasari, Nindy Dwi
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1552

Abstract

Antioxidants play a crucial role in maintaining cellular integrity and preventing various biological damage processes that underlie the development of degenerative diseases. Moringa oleifera leaves are known to contain bioactive compounds with antioxidant activity; however, comparative data on the antioxidant potential of crude and purified extracts remain limited. This study aimed to compare the antioxidant activity of crude and purified Moringa oleifera leaf extracts using the DPPH method. Extraction was performed by maceration with 96% ethanol, followed by purification through liquid–liquid extraction using an ethanol–n-hexane mixture (1:1). Phytochemical screening was conducted on both extracts, and antioxidant activity was evaluated at concentrations of 20–100 ppm in triplicate. IC₅₀ values were determined using linear regression and statistically analyzed. The yields of the crude and purified extracts were 20.77% and 13.50%, respectively. Phytochemical analysis confirmed the presence of flavonoids, tannins, and saponins in both extracts. The purified extract exhibited stronger antioxidant activity (IC₅₀ = 68.040 ± 0.140 ppm) compared to the crude extract (IC₅₀ = 77.372 ± 0.312 ppm) (p < 0.05), although both were less potent than vitamin C as a positive control (IC₅₀ = 5.823 ± 0.128 ppm). These findings indicate that the purification process enhances the antioxidant potential of Moringa oleifera leaves by concentrating active components. This study provides scientific support for the potential use of purified Moringa leaf extract as an active ingredient in natural antioxidant supplements or cosmetic formulations.
OPTIMASI FORMULA DAN EVALUASI MASSA CETAK TABLET HISAP BERBAHAN YOGURT DENGAN METODE SIMPLEX LATTICE DESIGN Pujianti, Ayu; Nawangsari, Desy; Febrina, Dina
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1558

Abstract

Yocanserah® yogurt contains peanuts, ginger, and lemongrass, which have potential anti-diabetic properties. Yocanserah has a limited shelf life and sour taste, so it needs to be developed into a more acceptable lozenge formulation with a longer shelf life. The purpose of this study is to optimize the formulation of yogurt-based lozenge tablets using the simplex lattice design method. The materials or factors used in the optimization were Avicel PH 102, isomalt, and SSG, with the response being flow rate and compressibility. The data were analyzed using Design Expert software with the simplex lattice design method. The yogurt-based lozenge tablet mass was made using the wet granulation method with gelatin solution as a binder. The results showed that the tablet mass with variations in Avicel PH 102, isomalt, and SSG made using the wet granulation method produced flow rate and compressibility in accordance with the specifications. The use of variations in these three ingredients had a significant effect on the flow rate and compressibility of the tablet mass with a p-value < 0.05. The optimal formula for yogurt-based lozenge molding mass was obtained with a proportion of 49% Avicel PH 102, 1% isomalt, and 5% SSG, which produced a flow rate of 5.58 g/s and compressibility of 6.69% with a resulting desirability value of 0.311.
PENGARUH PERBANDINGAN FASE GERAK PADA ANALISIS DEKSAMETASON MENGGUNAKAN HPLC : NARRATIVE REVIEW Hening, Putik Titian Citra; Rahayu, Ihsanti Dwi; Iqbal, Muhammad; Triyandi, Ramadhan
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1561

Abstract

Dexamethasone is a synthetic glucocorticoid widely used in the treatment of inflammatory, allergic, and autoimmune diseases; therefore, accurate analytical methods are required to ensure its quality and safety. High Performance Liquid Chromatography (HPLC) is an analytical technique that is currently widely applied due to its high sensitivity, selectivity, and reliability for pharmaceutical analysis. In HPLC method development, the selection of the mobile phase can significantly influence separation quality, resolution, column efficiency, retention time, sensitivity, and analytical reproducibility. Consequently, appropriate mobile phase selection is a major concern in achieving accurate, precise, and efficient analytical methods. However, to date, no review article has comprehensively compiled and discussed the effect of mobile phase variations specifically on dexamethasone analysis using HPLC. This review article aims to evaluate the effect of variations in mobile phase composition in HPLC analytical methods on the quality of dexamethasone analysis. A literature search was conducted using Google Scholar, PubMed, and Scopus databases, with inclusion criteria consisting of full-text articles published between 2015 and 2025 in Indonesian or English. Based on the selection and screening process, ten articles met the eligibility criteria and were included for further analysis. The results of this review indicate that mobile phase composition plays a crucial role in chromatographic separation performance and method validation parameters. Mobile phases containing a high proportion of organic solvents, particularly acetonitrile, tend to produce shorter retention times, improved peak symmetry, and sharper peak shapes. Meanwhile, the addition of buffer systems to the mobile phase improves pH stability, sensitivity, and linearity.

Page 22 of 23 | Total Record : 226

 19   20   21   22   23 

Filter by Year

2021 2025


Reset
Filter By Issues
All Issue Vol 5 No 4 (2025): Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 5 No. 2 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 5 No. 1 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 4 No. 2 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 4 No. 1 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 3 No. 4 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 3 No. 3 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 3 No. 2 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 3 No. 1 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 2 No. 4 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 2 No. 3 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 2 No. 2 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 2 No. 1 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 1 No. 4 (2021): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 1 No. 3 (2021): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 1 No. 2 (2021): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 1 No. 1 (2021): Jurnal Buana Farma : Jurnal Ilmiah Farmasi More Issue