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Fakultas Kedokteran dan Ilmu Kesehatan Universitas Warmadewa Gedung F2 Lantai 3, Jl. Terompong No.24 , Sumerta Kelod, Kec. Denpasar Tim., Kota Denpasar, Bali 80239
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Aesculapius Medical Journal
Published by Universitas Warmadewa
ISSN : 28290712     EISSN : 28086848     DOI : https://doi.org/10.22225
Core Subject : Health, Science, Education,
Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
AMJ (Aesculapius Medical Journal) is a peer-reviewed medical journal that published research articles and theoretical articles in medical science. This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. It aims is to provide a place for academics and practitioners to publish original research articles, review articles, and book reviews. The scope of this journal area any topics concerning medical studies in all aspects. AMJ (Aesculapius Medical Journal) published by Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa 3 times a year. AMJ (Aesculapius Medical Journal) is available in print and online version. AMJ (Aesculapius Medical Journal) is Available online at https://www.ejournal.warmadewa.ac.id/index.php/amj/index, since Volume 1 No 1 October, 2021.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
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Search results for , issue "310-318" : 1 Documents clear
Pektin Dan Potensinya Sebagai Intervensi Nutrisi Anti Kolesterol Pada Pencegahan Penyakit Kardiovaskular Septian Aulia Najwa; Feni Rahmawati Putri; Muhammad Rifqi Aminullah
Aesculapius Medical Journal 310-318
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.6.1.2026.310-318

Abstract

Abstract Cardiovascular disease remains a leading cause of mortality worldwide, with dyslipidemia, particularly elevated total cholesterol and LDL-C, as one of the most significant risk factors. This study aims to review the role of pectin, a soluble fiber from fruits and vegetables, as a non-pharmacological nutritional intervention in the prevention of cardiovascular disease. A narrative literature review was conducted using PubMed and Scopus databases, covering publications from 2020 to 2025. The findings indicate that consuming 6–15 g/day of pectin can reduce LDL levels by up to 7% without affecting HDL-C. The main mechanisms include increasing intestinal viscosity to inhibit lipid absorption, binding bile acids to enhance cholesterol excretion, and fermentation by gut microbiota to produce short-chain fatty acids (SCFAs), particularly propionate, which suppresses hepatic cholesterol synthesis. In addition, pectin improves glycemic control, insulin sensitivity, and exerts anti-inflammatory effects, contributing to overall cardiometabolic health. In conclusion, pectin shows promise as a nutritional strategy for lowering cholesterol and preventing cardiovascular disease risk, although further standardized long-term clinical studies are needed to confirm its effectiveness and consistency. Keywords: Pectin, soluble fiber, cholesterol, dyslipidemia, cardiovascular disease

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