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International Journal of Health and Pharmaceutical (IJHP)

IJHP
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Published by CV. Inara

ISSN : - EISSN : 2808845X DOI : https://doi.org/10.51601/ijhp

Core Subject : Health,

Nursing Public Health

International Journal of Health and Pharmaceutical (IJHP) e- ISSN : 2808-845X is a communication media and scientific publication in the health and pharmaceutical fields published by Inara Publisher. International Journal of Health and Pharmaceutical (IJHP) contains articles from research focusing on basic medicine, clinical medicine, epidemiology, preventive medicine (social medicine), pharmacy, and other medical fields. International Journal of Health and Pharmaceutical (IJHP) is published periodically four times a year (February, May, August and November).

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)

Articles 517 Documents

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Effectiveness Of Incision Wound Healing Of Pandanus Amaryllifolius Roxb In Wistar Rats Putri, Muna Soraya; Girsang, Ermi; Chiuman, Linda; Ginting, Chrismis Novalinda
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 2 (2022): May 2022
Publisher : CV. Inara

The incision is a condition of tissue discontinuity that is commonly encountered with the risk of prolonged healing time, imperfect wound healing, infection, etc. Assessment of the wound healing activity of the incision is the purpose of this research, which includes an examination of wound contraction, the thickness of collagen fibers, and the number of new blood vessels formation. In total, 25 rats will be divided into 5 test groups, each consisting of 5 rats; the control group (cream base treated), standard group (Povidone Iodine), followed by the treated group with 10%, 20%, and 30% pandan leaf extract ointment. The preliminary screening of phytochemical analysisshowed the presence of alkaloids, saponins, flavonoids, tannins, triterpenoids, and steroids and glycosides, with the total content of phenols and flavonoids from the ethanolic extract of Pandan Wangi is 20.95 GAE mg/gram extract, and 23.57 TAE mg/gram extract. Wound contraction examination result showed a significant difference between the treatment groups on day 16 and a sign the pairs of groups after being given the ointment with each concentration (p <0.05), especially in the group with 30% fragrant leaves extract and the standard group. Examination of new blood vessels showed a significant difference (p <0.05), especially with 30% of the leaves extract ointment. There was also a significant difference in collagen density in the group given pandanus ethanol ointment, especially at the 30% pandanus extract content against the group that was only given the ointment base. This research strongly suggests that the fragrant pandan leaf extract ointment is effective in healing incisional wounds and promises the potential for further studies on the pharmacological aspects.

Evaluation Of Planning And Implementation Occupational Safety And Health In Hospital Embung Fatimah Batam In 2021 Noni Rokaya Pasaribu; Ermi Girsang; Sri Lestari Ramadhani Nasution; Chrismis Novalinda Ginting
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 2 (2022): May 2022
Publisher : CV. Inara

Hospital occupational health programs have not been fully implemented in hospitals such as evaluation of the work environment, documentation of special and periodic health checks, the risk of occupational diseases (PAK). This type of research is qualitative with 10 informants selected purposively. on the input component: HR K3, the budget, and safety facilities provided are still lacking. In the process component: Risk management, hospital safety and security efforts, occupational health services, and B3 management are good. There are not enough fire prevention and control facilities. Infrastructure management is good with water sources, backup electricity, and periodic maintenance. Management of medical equipment and disaster preparedness is good. In the output component: Supervision is carried out by internal hospitals cases of work accidents are still found, and there is still a shortage of human resources, budget, and K3 facilities. It is recommended to the management of the hospital to add human resources in the field of work safety according to standard.

Testing Antioxidant And Antibacterial Activity Of Andaliman Fruit (Zanthoxylum Acanthopodium Dc.) Ethanol Extract With Abts Method (2,2'-Azino-Bis(3-Ethylbenz-Thiazoline-6-Sulfonic Acid) And Minimum Resistant Concentration Agung Adha Witasa Dewana; Tan Suyono; Linda Chiuman; Sahna Ferdinand Ginting
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 1 (2022): February 2022
Publisher : CV. Inara

Antioxidants are chemical compounds that can donate one or more electrons to free radicals, so that these free radicals can be quenched. There are two sources of antioxidants, namely natural and synthetic antioxidants. Andaliman (Zanthoxylum acanthopodium DC.) is one of the many spice plants found in Toba Samosir and North Tapanuli Regencies, North Sumatra. Andaliman plants grow at an altitude of 1,500 m above sea level. Apart from North Sumatra. This research using method experimental research when collecting and processing andaliman fruit, making simplicia, making ethanol extracts and examining antioxidant activity tests using the ABTS free radical scavenging method (2,2'-azino-bis(3-ethylbenz-thiazoline-6-sulfonic acid) and antibacterial activity. using the minimum inhibitory concentration method. Testing the antioxidant activity of the ethanol extract of andaliman fruit with the ABTS method using a UV-VIS spectrophotometer with a wavelength of 734 nm. the regression equation (y = 0.4619 + 20.226) obtained an IC50 value of 64.4598 mg/mL which can be classified as a strong antioxidant activity. The results of the antibacterial activity test of the ethanol extract of the andaliman fruit showed that the extract had antibacterial activity in the moderate category at a concentration of 300 mg/ml with an inhibition zone of 10.

Test of Antioxidant And Antibacterial Activity of Ethanol Extract of Andaliman Fruit (Zanthoxylum Acanthopodium Dc.) With Dpph (1.1-Diphenyl-2-Picrylhydrazil) Trapping Method And Minimum Inhibitory Concentration Ira Syaputri; Ermi Girsang; Linda Chiuman
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 2 (2022): May 2022
Publisher : CV. Inara

Utilization of bioavailability according to World Health Organization (WHO) records is very large, it is estimated that almost 80% of mankind, especially in developing countries, still use plants as medicinal ingredients to maintain their health (Nugraheni, 2007). Andaliman (Zanthoxylum acanthopodium DC.) which belongs to the Rutaceae tribe which is one of the plants known to the Batak community, is classified as a wild plant and is a typical plant of Province North Sumatra. The method used in this research is experimental research. The research included collecting and processing andaliman fruit, making simplicia, making ethanol extracts, and examining antioxidant activity tests using the DPPH free radical scavenging method (1,1-diphenyl-2-picrylhydrazil) and antibacterial activity using the minimum inhibitory concentration method. The results of the antibacterial activity test of the ethanolic extract of andaliman fruit showed that the extract had antibacterial activity in the moderate category at a concentration of 300 mg/ml with an inhibition zone of 10.17 mm for Staphylococcus aureus bacteria and a moderate category for Staphylococcus epidermidis bacteria with an inhibition zone of 10.80 mm. The ethanol extract of andaliman fruit can inhibit Staphylococcus aureus and Staphylococcus epidermidis, effective at a concentration of 300 mg/ml with inhibitory diameters of 10.17 mm and 10.80 mm, respectively.

Analyzed Psychological Impact Of An Effect Of Covid-19 On Mental Health On Health Personnel In Hospital Putri Hijau Medan Dessy Series Ulina Ginting; Santy Siregar; Yolanda Eliza Putri Lubis; Chrismis Novalinda Ginting
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 1 (2022): February 2022
Publisher : CV. Inara

The performance of nurses in hospitals is closely related to reliable, skilled, and professional human resources. Many factors that make it difficult for a person to care for a child are, in fact, length of work, training, motivation, incentives, work environment, and supervision.This research is for the treatment of the factors that is used in the preparation of nurse performance an analytical study with a cross-sectional approach (cross sectional). The research was conducted at Raden Mattaher Hospital, Jambi Province was 406 people and a sample of 261 people. Sampling by purposive sampling. Analyze the data with univariate, bivariate with chi-square test, and multivariate with multiple logistic regression at 95% confidence level ( = 0.05). The results showed that The factors in the development of Rumar General Hospital Raden Mattaher Jambi Province are education and training (p = 0.000), motivation (p = 0.000), incentives (p = 0.020), and supervision (p = 0.002). The variable that has no effect is age (p = 0.584), education (p = 0.786), length of work (p = 0.421), and work environment (p = 0.166). The most dominant variable affecting the performance of nurses is motivation with a value of Exp (B) / OR = 5.626, meaning that nurses who have high motivation have a 5.6 times higher chance of good performance than nurses with low motivation.

An Effect Virgin Coconut Oil Oral And Topical On Volume Decrease Of Foot Edema Of Male Wistar Flows Induced By –Caragenan Dzil Fikri; Ermi Girsang; Ali Napiah Nasution; Linda Chiuman
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 1 (2022): February 2022
Publisher : CV. Inara

Virgin Coconut Oil(VCO) is virgin coconut oil that is made enzymatically. The content of saturated fatty acids and flavonoid compounds in VCO can be used as an anti-inflammatory drug. This study aims to determine the activity of VCO as an anti-inflammatory. Anti-inflammatory activity was tested using the method of calculating the percentage of inflammation inhibition in white rat paws induced by intraplantar 1% carrageenan solution. The decrease in edema in the rat's feet was measured using a plethysmometer for 360 minutes. The results showed that VCO at a dose of 0.4 ml/200 g BW and 0.8 ml/200 g BW gave anti-inflammatory activity with the percentage of inflammation inhibition of 64.34 ± 9.90 and 52.66 ± 8, respectively. 94. The anti-inflammatory activity of VCO at a dose of 0.4 ml/ 200 g BW and a dose of 0.

The Relationship Of Family Support With The Liveliness Of The Following Gymnastics In Patients With Diabetes Mellitus Type DuaDi Club Prolanis Diamen Barigas BPJS Office Palangka Raya Untung Halajur; Sri Widya; Aida Kusnaningsih
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 1 (2022): February 2022
Publisher : CV. Inara

Physical exercise is one of the pillars of diabetes management that needs to be cultivated, because there are many benefits that can be felt by people with DM. The number of benefits that can be felt by patients with DM, it is very necessary activeness of DM patients in doing one gym gymnastics. Activity of DM patients can also be influenced by several factors one of which is family support. This study aims to determine whether there is a relationship of family support with the activity of following gymnastics in people with diabetes mellitus type two. Thisused study observational research Cross Sectional. Instruments include family support questionnaires and liveliness forms. The population in this study were members of Club Prolanis Diamen Barigas BPJS Office Palangka Raya who experienced DM and samples in the study were two types of DM patients who followed the gymnastics activities as much as 30 respondents using sampling technique that is total sampling. Univariate analysis using frequency distribution table and bivariate analysis usingtest Chi-Square. The results showed that there was a significant correlation between family support and activeness following gymnastics in patients with type 2 diabetes mellitus At Club Prolanis Diamen Barigas BPJS Office Palangka Raya, with the result of statistical test of continuity correction known that significance p value of 0,046 with α < (0.05). There is a relationship between family support and active follow gymnastics in patients with type 2 diabetes mellitus at Club Prolanis Diamen Barigas BPJS Palangka Raya.

Direct Medical Costs Related To Clinical Outcomes And Patterns Of Ischemic Stroke Drug Therapy In Panti Rapih Hospital Yogyakarta Muslimah; Nina Anggraeni Noviasari; Nandhini Lawrence Anantaizaldy
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 2 (2022): May 2022
Publisher : CV. Inara

This study aimed to analyze clinical outcomes related to direct medical cost and the pattern of drug therapy. This was an analytical observational study with retrospective and concurrent data through observation from the perspective of the hospital. A total of 42 stroke ischaemic patients were enrolled in this study. Data were collected with a period of 1 year after the first stroke occurrence, which began on May 15th, 2019 until June 15th, 2020. Data sources used in this study include medical records, financial data, and drug data from pharmacies. Data were analyzed using the Mann-Whitney U test and the Kruskal-Wallis test. This study findings showed the highest sociodemographic data on age 41-70 years (54,76%), male (59,52%), length of stay of 5-10 days (66,60%), comorbid of hypertension (88,10%), complication of urinary tract infection (19,05%), CCI 3-5 (85,71%), condition at hospital admission of hemiparesis (83,72%), and Antiplatelet drug therapy (90,48%). Clinical outcomes of disability mostly occurred in males (59,52%), age 41-70 years (54,76%), and length of stay of 5-10 days (66,67%). There were 48 events of clinical outcomeincluding 14,29% recurrent stroke and disability (n=6), 100% disability (n=42) and no mortality (n=0). Recurrent stroke and disability were not associated with a direct medical cost per year, neither inpatient nor outpatient cost. This might be due to the severity of stroke at the hospital admission which not be considered in this study. In conclusion, this study’s findings could be used as consideration in the determination of health policy, health insurance, and data source for pharmacoeconomic.

Stunting Risk Factors In Children Under 5 Years Old In Indonesian Border Regions (North Kalimantan-Malaysia) Yulianti, Ika; Nurasmi, Nurasmi; Padlilah, Rahmi
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 2 (2022): May 2022
Publisher : CV. Inara

Stunting in children becomes a health problem that gets priority and must be addressed immediately, especially at the border. Stunted development, decreased cognitive function and immune function as well as the risk of diabetes mellitus, coronary heart disease, hypertension and obesity are the effects of stunting. The aim of the study was to systematically find out the risk factors for stunting on the North Kalimantan-Malaysia border. Methods of using systematic review. Research from as many as 454 articles later in PRISMA analysis into 10 articles came from databases such as Pubmed, Science Direct, google scoolar. The results showed that the risk factors for stunting are Birth Length, Exclusive breast milk companion food, exclusive breastfeeding, family opinion, maternal factors namely age, attitude, occupation, knowledge, education and height.

Analysis of Efficiency Of KDT-OAT and Removal Preparations on The Recovery of Pulmonary Tuberculosis Duha, Kristin Berlianta; Lestari Ramadhani Nasution, Sri; Girsang, Ermi; Suyono, Tan
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 2 (2022): May 2022
Publisher : CV. Inara

Background: Tuberculosis is one of the 10 most common causes of death and is the single most common cause of infection and causes illness every year in millions of people. The etiology of tuberculosis is the bacteria Mycobacterium tuberculosis and Mycobacterium bovis. These germs have a size of 0.5-4 microns x 0.3-0.6 microns with thin rods, straight or slightly bent, granular or have no sheath, but have a thick outer layer consisting of lipoids (especially mycolic acid). Based on data from the Riset Kesehatan Dasar in 2018 conducted by the Kementerian Kesehatan RI, the prevalence rate of pulmonary TB by doctors in Indonesia in 2018 was the same as in 2013 which was 0.4%. Based on the OAT guidelines used in Indonesia, there are two OAT drug preparations, namely OAT-KDT or (FDC) and the Kombipak package. Comparison of the efficacy of this drug in curing pulmonary TB also varies. Objective: To determine the efficacy of KDT-OAT and removal preparations on the cure rate of pulmonary TB. Methods: This type of research is a retrospective cohort study, which is a time-period approach. This study was conducted in October-November 2020. Results: There was no significant difference in treatment outcomes in pulmonary TB patients who received OAT-KDT or OAT-release preparations.

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Arman Harahap

Contact Email armanhrahap82@gmail.com

Phone +6285370005518

Journal Mail Official armanhrahap82@gmail.com

Editorial Address Jl. SM. Raja, No 27, Kab. Labuhanbatu, Provinsi Sumatera Utara, 21419

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Abstract

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Contact Name
Arman Harahap

Contact Email
armanhrahap82@gmail.com

Phone
+6285370005518

Journal Mail Official
armanhrahap82@gmail.com

Editorial Address
Jl. SM. Raja, No 27, Kab. Labuhanbatu, Provinsi Sumatera Utara, 21419

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