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Tirtayasa Medical Journal
Published by Universitas Sultan Ageng Tirtayasa
ISSN : -     EISSN : 28095111     DOI : -
Core Subject : Health, Agriculture,
Agriculture, Biological Sciences & Forestry Health Professions Medicine & Pharmacology Nursing Public Health
Tirtayasa Medical Journal provides a forum for publishing the original research articles, review articles, and study case from contributors and the novel technology news related to medicine and health. This journal encompasses original research articles, review articles, and case study, Scope : Medical; Biomedical; Nursing; Nutrition and Food Sport and health Occupational Health Public Health
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Articles 57 Documents
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Implementasi Proses Asuhan Gizi Terstandar pada Pasien Diabetes Melitus dengan Berbagai Komorbiditas: Study Kasus Betty Yosephin Simanjuntak; Lydia Fanny; Derie Erawan; Titi Enyliana
Tirtayasa Medical Journal Vol 5, No 2 (2026): May
Publisher : Universitas Sultan Ageng Tirtayasa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62870/tmj.v5i2.39621

Abstract

Diabetes mellitus is a metabolic disorder characterized by chronic and sustained elevations in blood glucose levels. Type 2 diabetes mellitus is the most common type and is often accompanied by complications such as hypertension, anemia, and urinary tract infections. This study aims to assess the results of implementing a standardized nutritional care process in patients with type 2 diabetes mellitus with complications of hypertension, anemia, and urinary tract infections. This study used an observational design with a case study approach in an inpatient (Tn H, 56 years) at Harapan Doa Hospital in Bengkulu City for three days of observation. The nutritional care process included assessment, diagnosis, intervention, and monitoring and evaluation. Data collected included dietary intake, anthropometry, biochemistry, and the patient's clinical physical condition. The results showed a gradual increase in energy and protein intake during the intervention, as well as a decrease in random blood sugar levels from 363 mg/dL to 157 mg/dL. In addition, there was an improvement in clinical condition, characterized by stabilization of vital signs and a decrease in blood pressure to near normal. Thus, the implementation of standardized nutritional care through a diabetes mellitus diet and the DASH dietary approach is effective in helping improve the patient's metabolic and clinical conditions.
Infeksi Cacing dan Akses Jamban serta Air Bersih pada Anak Usia Sekolah Dasar Munirah Siregar; Silvia Fitrina Nasution; Minsarnawati Minsarnawati; Mukhlidah Hanun Siregar
Tirtayasa Medical Journal Vol 5, No 2 (2026): May
Publisher : Universitas Sultan Ageng Tirtayasa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62870/tmj.v5i2.38425

Abstract

Soil-transmitted helminthiasis (STH) remains a public health problem among school-aged children, particularly in marginalized urban settlements with inadequate sanitation. Objective: To describe the prevalence of helminth infection and household access to latrines and clean water among school-aged children in Yayasan Nanda Dian Nusantara, Ciputat Timur, South Tangerang. A descriptive cross-sectional study was conducted (October–December 2011). Consecutive sampling recruited 35 elementary-school-aged children. Data on sanitation and water were collected using questionnaires and household observations. Stool samples were examined using wet mount smear and Harada–Mori culture to identify helminth eggs/larvae. Overall, 9 of 35 children (25.7%) were positive for helminth infection. None of the participants had ever taken deworming medicine. Hookworm infection was the most common (5/9; 55.6%), followed by Fasciolopsis buski (1/9; 11.1%) and Strongyloides stercoralis (1/9; 11.1%). Two cases (22.2%) could not be identified to the species level. Most households lacked a private latrine (28/35; 80.0%) and reliable access to clean water (29/35; 82.9%). The prevalence of helminth infections was substantial and coincided with poor access to sanitation and clean water. Integrated school- and community-based strategies combining periodic deworming, hygiene promotion, and Water, Sanitation, and Hygiene (WASH) improvements are needed to reduce transmission and reinfection.
Hipoksia Intermiten sebagai Pemicu Disfungsi Mitokondria: Tinjauan Naratif Mekanisme Seluler Dwi Widyawati; Ghea Farmaning Thias Putri
Tirtayasa Medical Journal Vol 5, No 2 (2026): May
Publisher : Universitas Sultan Ageng Tirtayasa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62870/tmj.v5i2.39071

Abstract

Intermittent hypoxia is characterized by recurrent cycles of oxygen deprivation and reoxygenation, commonly observed in chronic diseases such as obstructive sleep apnea, respiratory disorders, and metabolic conditions. Compared to continuous hypoxia, it induces more dynamic cellular stress, particularly affecting mitochondrial function. This review aimed to analyze the cellular mechanisms by which intermittent hypoxia triggers mitochondrial dysfunction. A structured narrative literature search was conducted using PubMed, Scopus, ScienceDirect, and Google Scholar. A total of 104 articles were identified, of which 22 met the inclusion criteria and were included in the analysis. Selected studies were descriptively synthesized to identify key mechanisms. Intermittent hypoxia disrupts mitochondrial electron transport chain activity, especially at complexes I and III, leading to electron leakage and increased reactive oxygen species (ROS). Recurrent oxidative stress causes mitochondrial membrane damage, protein oxidation, mitochondrial DNA injury, reduced ATP synthesis, and impaired cellular bioenergetics. It also alters mitochondrial dynamics and weakens antioxidant defenses. Intermittent hypoxia is a major trigger of mitochondrial dysfunction through repetitive oxidative stress, contributing to metabolic disturbances and organ dysfunction.
Pengembangan Puding Sari Kacang Koro Pedang (Canavalia ensiformis) dan Sari Buah Naga Merah (Hylocereus polyrhizus Sebagai Makanan Tambahan Penyuluhan Balita Putri Faras Najibah; Rakhmi Setyani Sartika; Fahruddin Perdana
Tirtayasa Medical Journal Vol 5, No 2 (2026): May
Publisher : Universitas Sultan Ageng Tirtayasa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62870/tmj.v5i2.34991

Abstract

Balita dengan status gizi kurang perlu diberikan intervensi pemberian makanan tambahan seperti modisco. Pengembangan modisco dari kacang koro pedang serta pengembangan bentuk menjadi puding dengan penambahan pewarna alami untuk meningkatkan tingkat kesukaan dapat dijadikan pilihan sebagai makanan tambahan untuk balita gizi kurang. Penelitian ini bertujuan untuk mengetahui tingkat penerimaan terbaik dari formulasi puding modisco dengan substitusi kacang koro pedang dan penambahan buah naga merah. Metode penelitian ini adalah eksperimen dengan Rancangan Acak Lengkap (RAL) dengan empat kategori. Kategori tersebut ada F0, F1, F2, dan F3 dengan perbandingan susu dan kacang koro pedang pada masing-masing formula yaitu 1SS:0KKP, 3SS:1KKP, 1SS:3KKP, dan 1SS:1KKP. Tingkat kesukaan panelis berdasarkan parameter warna yang paling banyak disukai adalah F3, parameter aroma F0, parameter rasa F3, parameter tekstur F2 dan F3, serta untuk parameter keseluruhan F0. Berdasarkan uji De Garmo untuk menentukan formulasi terpilih dari parameter prioritas, F3 merupakan formulasi terpilih. Hasil uji proksimat pada F3 sebagai formula terpilih dari Puding Modisco dengan Substitusi Kacang Koro Pedang dan Penambahan Buah Naga Merah yaitu kadar karbohidrat by difference 11,75%, kadar protein 1,05% kadar lemak total 1,24%, kadar abu 0,15%, kadar air 85,82%, energi total per 100 gram berat pada Puding Modisco dengan Substitusi Kacang Koro Pedang dan Penambahan Buah Naga Merah adalah sebesar 62,32 kkal. Perbandingan kecukupan gizi makro dengan Acuan Label Gizi (ALG) kelompok 1-3 tahun dari formulasi terpilih produk puding modisco %ALG energi sebesar 5%, karbohidrat sebesar 5%, protein 5%, dan lemak 3%.
Lentigo Senilis (Solar Lentigo): Tinjauan Naratif tentang Epidemiologi, Patogenesis, Gambaran Klinis, Diagnosis, dan Penatalaksanaan Erika Agustianti; Luluk Hermawati; Nur Bebi Ulfah Irawati; Ratu Nadia; Firda Asma’ul Husna; Hilizza Awalina Zulfa
Tirtayasa Medical Journal Vol 5, No 2 (2026): May
Publisher : Universitas Sultan Ageng Tirtayasa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62870/tmj.v5i2.39252

Abstract

Lentigo senilis, also known as solar lentigo, is a common benign hyperpigmented lesion that is closely associated with chronic ultraviolet (UV) exposure and the skin aging process. Although non-malignant, lentigo senilis represents an important manifestation of photoaging and often causes cosmetic concerns, particularly among older individuals. This review aims to summarize current evidence regarding the epidemiology, pathogenesis, clinical characteristics, diagnostic approaches, and management of lentigo senilis using a thematic narrative review approach. A comprehensive literature search of major electronic databases identified relevant studies published between 2015 and 2025. The findings indicate that the prevalence of lentigo senilis increases significantly after the age of 50 years, particularly in individuals with cumulative sun exposure and lighter skin phototypes. The pathogenesis involves UV-induced melanocyte activation, dysregulation of melanogenesis signaling pathways, oxidative stress, and age-related decline in epidermal repair capacity. Clinically, lentigo senilis presents as flat, well-demarcated hyperpigmented macules on sun-exposed areas of the skin. Diagnosis is primarily established through clinical examination and dermoscopy to exclude malignant lesions with similar appearances. Management options include topical depigmenting agents, chemical peels, cryotherapy, laser-based therapies, and intense pulsed light, tailored to lesion characteristics and patient preferences. Preventive strategies emphasizing sun protection remain essential in reducing the incidence and progression of lentigo senilis.
Hubungan Tingkat Pengetahuan Dengan Sikap Lansia Dalam Pencegahan Osteoporosis di Desa Ketanjung Karanganyar Demak Mukhlishoh Mukhlishoh; Akhmad Safi'i; Athi’ Linda Yani; Devin Prihar Ninuk
Tirtayasa Medical Journal Vol 5, No 2 (2026): May
Publisher : Universitas Sultan Ageng Tirtayasa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62870/tmj.v5i2.36382

Abstract

Osteoporosis is a common condition among the elderly that can be reduced through improved knowledge and a positive attitude toward prevention. This study used a quantitative cross-sectional design to examine the relationship between knowledge level and attitude toward osteoporosis prevention among elderly residents of Ketanjung Village, Karanganyar, Demak. A total of 64 participants meeting the inclusion criteria—female elderly, willing to participate, not in an emergency condition, registered at the community health center as osteoporosis patients, able to carry out activities independently, and fully conscious—were selected using purposive sampling. Exclusion criteria included absence during the activity or not being registered at the health center. Data were collected using a validated and reliable closed-ended questionnaire, and analyzed with the Chi-Square test. Results showed that 70% of respondents had good knowledge of osteoporosis prevention, and 61% had a positive attitude toward preventive measures. Statistical analysis revealed a significant relationship between knowledge and attitude (p = 0.02), indicating that higher knowledge levels are associated with more positive attitudes. These findings suggest that structured, ongoing health education can enhance awareness and promote positive behavior toward bone health in the elderly. The study’s limitations include its restriction to one village and a small sample size, so further research with larger, more diverse populations is recommended to improve generalizability.
Asuhan Keperawatan Pada Pasien Gout Arthritis Dengan Ketidakpatuhan Diet Rendah Purin Muazam Nurfai Hardiansyah; Agung Eko Hartanto; Heru Wiratmoko; Yustina Purwaningsih; Gandes Widya Hendrawati
Tirtayasa Medical Journal Vol 5, No 2 (2026): May
Publisher : Universitas Sultan Ageng Tirtayasa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62870/tmj.v5i2.32372

Abstract

Gout Arthritis is an acid formed due to purine metabolism in the body. Purine comes from foods containing protein. To maintain uric acid levels within the normal range, individuals must improve compliance with a low-purine diet supported by Health Education. The purpose of this study was to determine how nursing care is provided to gout arthritis patients with low-purine diet non-compliance. The research design was descriptive qualitative with a case study approach. Nursing interventions focused on diet education using leaflet media which showed a significant increase in the level of patient diet compliance, namely the compliance score increased from 2 (non-compliant) to 10 (compliant) within 7 days and resulted in a decrease in uric acid levels from 8.9 mg/dl to 5 mg/dl. The provision of this research education confirms that structured health education and appropriate educational media can improve diet compliance and health outcomes in gout arthritis patients.

Page 6 of 6 | Total Record : 57

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