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Luluk Rosida
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Universitas Aisyiyah (UNISA) Yogyakarta Kampus Terpadu: Jalan Siliwangi (Ring Road Barat) No. 63, Nogotirto, Gamping, Sleman, Yogyakarta 55292, Indonesia Telepon: (+62274) 4469199
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JHeS (Journal of Health Studies)
Published by Universitas Aisyiyah Yogyakarta
ISSN : 25493345     EISSN : 25493353     DOI : https://doi.org/10.31101/jhes
Core Subject : Humanities, Health, Education,
Humanities Education Health Professions Nursing Public Health
JHeS (Journal of Health Studies) published since March 2017 by Universitas Aisyiyah Yogyakarta. Published twice a year in March and September. Contains the writings of research results with the theme health. ISSN print: 2549-3345, ISSN Online: 2549-3353. JHeS (Journal of Health Studies) particularly focuses on the main problems: Midwifery, Nursing, Radiology, Physiotherapy, Health Analyst, Nutrition, Health Management, Health-Accounting, Health Communication, Health Education, Public administration in health, Health Psychology, Biotechnology Health, Health Architecture, Health Information Technology Anastesiologi, Material and Health Technology, other. This journal has been ACCREDITED by National Journal Accreditation (ARJUNA) Managed by Ministry of Research, Technology, and Higher Education, Republic Indonesia with Second Grade (Peringkat 3, Sinta 3) since year 2018 to 2022 according to the decree No. 23/E/KPT/2019. Every article that goes to the editorial staff will be selected through Initial Review processes by Editorial Board. Then, the articles will be sent to peer reviewers and will go to the next selection by Blind Review Process. After that, the articles will be returned to the authors to revise. These processes take a month for a maximum time. For each manuscript, peer reviewers will rate the substantial and technical aspects, peer reviewers who collaborate with JHeS (Journal of Health Studies).
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 180 Documents
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Relationship of acid–base imbalance with hemorrhage volume and mortality in intracerebral stroke hemorrhage Gavin Mukti; Iwan Setiawan; Metana Puspitasari; Sulistyani Sulistyani
JHeS (Journal of Health Studies) Vol. 10 No. 1 (2026): Maret
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jhes.4008

Abstract

This study aimed to evaluate the relationship between acid-base balance disturbances and intracerebral hemorrhage volume with mortality rates in hemorrhagic stroke cases. The research used an observational analytic design with a cross-sectional approach and was conducted at Dr. Soeratno Gemolong General Hospital, Sragen, from September to November 2024. The study population consisted of medical records of patients diagnosed with hemorrhagic stroke at the hospital between August 2021 and August 2024 who met the inclusion criteria. A total of 50 samples were selected using a purposive sampling technique. Data analysis included univariate analysis, bivariate analysis using the Chi-Square test, and multivariate analysis using logistic regression. The results showed a significant relationship between acid–base balance disturbances and intracerebral hemorrhage volume with mortality in hemorrhagic stroke cases (p=0.001). In addition, intracerebral hemorrhage volume was significantly associated with mortality (p=0.007). Multivariate analysis confirmed that both acid–base imbalance and hemorrhage volume significantly influence mortality outcomes. These findings indicate that acid–base imbalance and intracerebral hemorrhage volume greater than 30 ml are strong predictors of mortality in hemorrhagic stroke patients. Therefore, strict monitoring of arterial blood gases, neurological status, and hemodynamic stability is essential during the acute phase of care. Early detection of physiological deterioration and prompt intervention may help reduce the risk of adverse outcomes. Future research is recommended to use prospective multicenter designs with larger sample sizes to further clarify causal relationships and evaluate whether early correction of acid–base disturbances can improve mortality outcomes in hemorrhagic stroke patients.
The effect of slow deep breathing exercise on IL-6 and IL-10 levels in hypertensive elderly: a pre-experimental study Abdillah Choirul Chisholi
JHeS (Journal of Health Studies) Vol. 10 No. 1 (2026): Maret
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jhes.4299

Abstract

Hypertension is a major risk factor for cardiovascular disease and is often associated with chronic inflammatory processes. Pro-inflammatory cytokines such as Interleukin-6 (IL-6) play a role in the pathogenesis of hypertension, whereas anti-inflammatory cytokines such as Interleukin-10 (IL-10) can inhibit inflammatory effects. Slow Deep Breathing Exercise (SDBE) has been linked to improved autonomic nervous system regulation and potential anti-inflammatory effects. This study used a one-group pretest-posttest design involving 35 pre-elderly and elderly participants with hypertension. Subjects underwent SDBE intervention for six weeks, three sessions per week, with each session lasting 10–15 minutes. IL-6 and IL-10 levels were measured using the ELISA method, and blood pressure was measured before and after the intervention. Data analysis was performed using the Wilcoxon Signed Rank Test. There was a significant increase in IL-10 levels after the intervention (p = 0.000), but IL-6 levels showed no significant change (p = 0.108). Systolic and diastolic blood pressure significantly decreased from 158.54±13.86 mmHg to 149.69±13.90 mmHg (p = 0.005) and from 88.80±15.08 mmHg to 84.66±8.99 mmHg (p = 0.005), respectively. In older adults with hypertension, slow deep breathing exercise can lower blood pressure and raise IL-10 levels, an anti-inflammatory cytokine, while IL-6 levels did not significantly change. This intervention can be used as a non-pharmacological therapy to help manage hypertension.
Effects of handgrip strength training on menopausal symptoms among active and inactive elderly community women Arkana Shalihat Agraj'ma; Siti Nadhir Ollin Norlinta; YuChuan Tsai; Suci Muqodimatul Jannah
JHeS (Journal of Health Studies) Vol. 10 No. 1 (2026): Maret
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jhes.4704

Abstract

Menopausal symptoms can reduce quality of life in elderly women and their severity is influenced by physical activity levels. In European regions approximately 70-80% women experiencing menopausal symptoms, whereas in America the proportion is around 60% and in Asia, reports indicate that approximately 10% of women in Japan and Indonesia experience menopausal symptoms. Hand grip training as a form of resistance training has the potential to increase muscle strength and help reduce menopausal symptoms. This study aims to evaluate the effect of hand grip training on menopausal symptoms in active and inactive elderly women in the community. The study used a  quasi-experimental pre-test and post-test two-group design consisting of 34 elderly women aged 50–60 years who were divided into active and inactive groups based on their physical activity levels using the International Physical Activity Questionnaire Short Form (IPAQ-SF) questionnaire. The hand grip training intervention was given for 4 weeks with a frequency of 3 times per week for 12 training sessions. Menopausal symptoms were measured using the Menopause Rating Scale (MRS). Data were analyzed using the Wilcoxon Signed Rank Test for the active group and Paired Sample T-Test for the inactive group. In the active group, the median MRS scored decreased from 7.00 to 6.00 (p=0.001). In the inactive group, the mean MRS scored decreased from 12.24±3.80 to 8.53±3.52 (p=0.000). Hand grip training siginificantly reduces menopausal symptoms in both active and inactive elderly with greater improvement observed in the inactive group. This simple exercise can be effectively implemented in community-based settings to help manage menopausal symptoms among postmenopausal elderly women.
The Relationship Between Cancer Stage And Quality Of Life In Cancer Patients Vita Setyaningsih; Hamudi Prasestiyo; Wantonoro Wantonoro
JHeS (Journal of Health Studies) Vol. 10 No. 1 (2026): Maret
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jhes.4714

Abstract

Cancer transcends physical pathology, manifesting as a chronic condition that imposes profound psychological, social, and spiritual burdens, often compromising the patient's quality of life (QoL). Recognizing that disease progression is a potential predictor of this decline, this study aims to analyze the correlation between cancer staging and quality of life. Conducted at PKU Muhammadiyah Gamping Hospital using an observational cross-sectional design, the study involved 75 cancer patients recruited via purposive sampling based on Slovin’s formula. Cancer staging data were validated through medical records and interviews, while QoL was assessed using the EORTC QLQ-C30 instrument. Data analysis using the Spearman Rank correlation test revealed that the majority of respondents presented with advanced-stage cancer and reported moderate-to-low QoL. A significant correlation was found (p-value 0,001), indicating an inverse relationship where advanced cancer stages are associated with lower quality of life. These findings underscore the urgency of early detection and comprehensive symptom management, including the optimization of palliative care. Consequently, this study recommends the integration of routine QoL assessments into clinical practice and the reinforcement of the nurse's role in the holistic management of cancer patients.
Aromatherapy for menstrual pain and premenstrual symptoms in women and adolescent girls: a scoping review Dwi Indah Wulandari; Catur Setyorini; Anita Dewi Lieskusumastuti; Lilik Hanifah
JHeS (Journal of Health Studies) Vol. 10 No. 2 (2026): September
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jhes.4734

Abstract

Dysmenorrhea is one of the most common gynecological disorders among women and can negatively affect quality of life. Its prevalence varies across regions, reaching 75.9% in Zimbabwe, 92.9% in France, 91.27% nationally in Indonesia, and approximately 74% among 43 adolescent girls in Denpasar. Aromatherapy is a complementary intervention used to alleviate menstrual pain and premenstrual symptoms. This scoping review aimed to identify the effectiveness of aromatherapy in reducing menstrual pain and premenstrual symptoms among adolescent girls and women. A scoping review was conducted using four databases: PubMed, ScienceDirect, Google Scholar, and ResearchGate. Articles were selected based on the following inclusion criteria: original research articles published between 2015 and 2025, written in Indonesian or English, involving participants aged 12–24 years who experienced premenstrual symptoms, and addressing aromatherapy for menstrual pain. Of 6,859 identified articles, seven met the inclusion criteria. Methodological quality was assessed using the Mixed Methods Appraisal Tool 2018 (MMAT) and Joanna Briggs Institute (JBI) appraisal tools. The seven included studies showed that aromatherapy can reduce dysmenorrhea intensity and menstrual symptoms. Lavender and rose aromatherapy demonstrated beneficial effects, whereas the effects of lemon and grapefruit aromatherapy varied. Dysmenorrhea intensity was also associated with several factors, including stress, anxiety, age at menarche, and body mass index. Aromatherapy has potential as a complementary non-pharmacological therapy to help reduce menstrual pain. However, physical and psychological factors should also be considered, and further research involving comparable participant groups across diverse populations and settings globally is needed.
Effectiveness of red spinach (Amaranthus tricolor) extract as an alternative to eosin in histological staining Yuyun Nailufar; Aji Bagus Widyantara; Yastifani Ilisne Kaka Mesa; Dritantiara Suci Manikum
JHeS (Journal of Health Studies) Vol. 10 No. 2 (2026): September
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jhes.4949

Abstract

The high usage of eosin as a cytoplasmic stain in histological preparations involves relatively high costs and poses potential environmental and toxicity risks, thereby necessitating a natural dye alternative. Red spinach (Amaranthus tricolor) contains anthocyanins, which have the potential to be used as a substitute for eosin. This study aim to compare the effectiveness of red spinach extract with eosin as a cytoplasmic stain in histological preparations. This study employed a quasi-experimental laboratory design with a descriptive quantitative approach involving 24 myoma tissue preparations divided into four groups: Hematoxylin-Eosin (control), and Hematoxylin combined with red spinach extract at concentrations of 10%, 20%, and 40%. Staining quality was assessed based on cytoplasmic staining intensity, nucleus-cytoplasm contrast, and tissue structure clarity by an anatomical pathologist. Statistical analysis was performed using the Kruskal-Wallis test followed by the Mann-Whitney test. The results showed a significant difference between the control group and all red spinach extract groups (p < 0.001). The Hematoxylin-Eosin group obtained the highest mean rank (21.50), while all red spinach extract groups shared the same mean rank (9.50). The findings indicate that red spinach extract at all tested concentrations has not been able to provide a staining quality equivalent to that of eosin. Unlike red spinach extract, which is a mixture of various natural compounds, eosin possesses more standardized chemical characteristics and usage, resulting in a more consistent dye. Staining histological preparations using hematoxylin combined with red spinach extract at concentrations of 10%, 20%, and 40% has not been able to produce a quality equivalent to eosin. This applies to the conditions of this study using extract concentrations of 10%, 20%, and 40% via the maceration method; therefore, it cannot yet be concluded that red spinach extract is generally unsuitable as an alternative to eosin. Future research is recommended to use higher extract concentrations, more optimal extraction methods, and longer staining durations.
Detection of Escherichia coli contamination in tofu, soaking water, and factory water sources Amelia Herlina; Nosa Septiana Anindita; Ika Afifah Nugraheni; Emanuel Kristanti
JHeS (Journal of Health Studies) Vol. 10 No. 2 (2026): September
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jhes.4711

Abstract

Indonesia is a country with rich diversity in the food sector, where small and medium enterprise (SME) tofu businesses grow rapidly. Tofu is highly popular due to its high nutritional value and affordability; however, manual processing and heavy water use make it susceptible to microbiological contamination, particularly by pathogenic Escherichia coli. This descriptive observational study aimed to determine the presence and microbiological quality of E. coli contamination in tofu, tofu soaking water, and factory water sources. The research was conducted from September 2023 - July 2024 across two tofu factories located in Kapanewon, Kasihan, Bantul Regency, Special Region of Yogyakarta. A total of 6 samples (comprising 2 samples tofu, 2 samples soaking water, and 2 samples water source samples) were evaluated using the Most Probable Number (MPN) method, morphological characterization, and biochemical testing. The results revealed that MPN values across all samples ranged from 6.8 to 120. All 6 samples (100%) exceeded the microbial contamination limit mandated by BPOM Regulation No. 13 of 2019 (<3 MPN/100 mL [atau g], SNI ISO 7251). Furthermore, morphological and biochemical tests confirmed that all 6 samples (100%) tested positive for E. coli. Consequently, the tofu processing, water sources, and sanitation practices at these production facilities do not meet the required microbiological hygiene standards, posing potential health risks to consumers.
Occurrence of colour doppler twinkle artifact in renal calculi with and without posterior acoustic shadowing Nursama Heru Apriantoro; Fatimah Putri Salfinah; Khairil Anwar
JHeS (Journal of Health Studies) Vol. 10 No. 2 (2026): September
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jhes.4912

Abstract

Nephrolithiasis affects approximately 7-15% of the global population. Conventional B-Mode ultrasonography has limitations detecting small renal calculi (<5 mm) or calculi lacking a distinct posterior acoustic shadow, whereas the Colour Doppler twinkle artifact has been reported to improve detection sensitivity; however, its occurrence across B-Mode sonographic patterns of nephrolithiasis remains unclear. This research aimed to describe the sonographic patterns (SP) of renal calculi on B-Mode ultrasonography and the occurrence of the Colour Doppler twinkle artifact within each pattern. A quantitative descriptive observational design combined primary and secondary data from 40 renal ultrasound images of patients with nephrolithiasis, collected consecutively from October 2025 to May 2026 at Hospital X. Data were analysed descriptively, and twinkle artifact occurrence between SP1 and SP2 was compared using Fisher's Exact Test. All 40 samples showed hyperechoic echogenicity on B-Mode, evenly divided into SP1 (hyperechoic with posterior acoustic shadow, 20 samples) and SP2 (hyperechoic without shadow, 20 samples). The twinkle artifact was detected in 37 of 40 samples (92.5%): 90% in SP1 and 95% in SP2 (p = 1.000). Three negative cases (7.5%), with stone sizes of 0.3-0.6 cm, were likely related to stone size and mineral composition. The Colour Doppler twinkle artifact may be a complementary feature to B-Mode ultrasonography, particularly in SP2 lesions without acoustic shadowing, and should be interpreted alongside B-Mode findings and clinical presentation; studies with a reference standard are needed.
Neuro-linguistic programming (NLP) self-talk reduces students’ academic anxiety Alifia Nita Ghumaishaa&#039; Basyar; Yasin Syarif Hidayatulloh; Zahro Varisna Rohmadani
JHeS (Journal of Health Studies) Vol. 10 No. 2 (2026): September
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jhes.5079

Abstract

The university years represent a transitional phase from adolescence to adulthood, characterized by various changes and demands in the academic, social, and psychological spheres. Course-related burdens such as assignments, examinations, and presentations frequently trigger psychological stress in the form of anxiety; if left unaddressed, this can impair concentration, diminish learning motivation, and negatively affect a student's overall mental health. This study aims to examine the effectiveness of the Neuro-Linguistic Programming (NLP) self-talk technique in reducing academic anxiety among students at Universitas 'Aisyiyah Yogyakarta. This study used a quantitative, quasi-experimental pretest-posttest control-group design involving 21 students: 11 in the intervention group and 10 in the control group. Data were collected using the Hamilton Rating Scale for Anxiety and analyzed through the Paired Samples T-Test and Mann-Whitney U Test. The findings indicated that the mean anxiety score in the intervention group decreased from 33.73 before the intervention to 15.73 after the intervention, while the control group showed a slight decrease from 34.10 to 34.00. The statistical analysis produced a p-value of 0.000 (p < 0.05), demonstrating a significant difference in anxiety levels between the two groups. Therefore, the NLP self-talk technique was found to be effective in reducing academic anxiety among students at Universitas 'Aisyiyah Yogyakarta. This study contributes to providing an alternative psychological intervention for managing academic anxiety and may support the development of counseling services in educational settings. The findings may also serve as practical input for applying self-talk techniques to assist students in managing negative thoughts and academic anxiety.
Treatment adherence, glucose monitoring behavior, and diabetic ulcer status in type 2 diabetes patients Putri Agustin; Arif Surjadi; Dini Sri Damayanti
JHeS (Journal of Health Studies) Vol. 10 No. 2 (2026): September
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jhes.5103

Abstract

Type 2 diabetes mellitus (T2DM) can lead to diabetic ulcers, and adherence to antidiabetic treatment and blood glucose monitoring behavior are modifiable components of its management. This study aimed to analyze the association of antidiabetic treatment adherence and blood glucose monitoring behavior with diabetic ulcer status in patients with T2DM at RSUD dr. Mohammad Zyn Sampang. This analytical observational study used a cross-sectional design involving 96 patients with T2DM recruited by consecutive sampling between May and July 2026. Treatment adherence was assessed using a modified eight-item Morisky Medication Adherence Scale, monitoring behavior using a structured questionnaire, and diabetic ulcer status from medical records. Data were analyzed using the Chi-square test, and odds ratios (OR) with 95% confidence intervals (CI) were calculated. Diabetic ulcers were present in 57 patients (59.4%). Non-adherence was found in 66 patients (68.8%) and inadequate monitoring behavior in 15 patients (15.6%). Adherence was not associated with ulcer status (57.6% vs 63.3% with ulcers; OR 0.79; 95% CI 0.32–1.91; p=0.594). Patients with inadequate monitoring behavior had a lower proportion of ulcers than those with adequate monitoring (33.3% vs 64.2%; OR 0.28; 95% CI 0.09–0.89; p=0.025). Age, diabetes duration, and comorbidity were not significantly associated with ulcer status. Treatment adherence was not associated with diabetic ulcer status, and the inverse association with monitoring behavior most likely reflects more frequent monitoring after ulcer onset rather than a protective effect of poor monitoring. Prospective studies are needed to clarify the temporal relationship.

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