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INDONESIA
Journal of Food and Pharmaceutical Science
Published by Universitas Gadjah Mada
ISSN : 20897200     EISSN : 23390948     DOI : https://doi.org/10.22146/jfps.581
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
FOCUS AND SCOPE Journal of Food and Pharmaceutical Sciences offers scientists, researchers, and other professionals to share knowledge of scientific advancements. The journal will publish original research articles, review articles, short communication, and letter to editor. The area of focus should cover all aspects of food and pharmaceutical sciences. The range of topics covered in the journal include: New Horizons in Food Research Food Chemistry Integrated Food Science Health, Nutrition, and Food Food Engineering, Materials Science, and Nanotechnology Toxicology and Chemical Food Safety Food Microbiology and Safety Drug Discovery Computational Chemistry and Molecular Modeling Pharmaceutical Biotechnology and Protein-Peptide Chemistry Pharmaceutics, Biopharmaceutics, Drug Delivery, and Pharmaceutical Technology Pharmaceutical Nanotechnology Pharmacokinetics, Pharmacodynamics, and Drug Transport Metabolism Analytical and Bioanalytical Chemistry Pharmaceutical Chemistry Natural Medicine and Nutraceutical Chemical Processing of Pharmaceuticals including Crystallization, Lyophilization, and Chemical Stability of Drugs Immunology, Biochemistry, and Cell and Molecular Biology
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 291 Documents
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Dragon Fruit Stem Powder as a Suspending Agent in Ibuprofen Suspension: Formulation and Characterization Nellisa Salsabila; Ririn Suharsanti; Intan Martha Cahyani
Journal of Food and Pharmaceutical Sciences Vol 14, No 4 (2026): J.Food.Pharm.Sci (In Press)
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.29116

Abstract

Indonesia is one of the tropical countries that produces dragon fruit which is an antioxidant. The high market demand for dragon fruit encourages farmers to increase yields by pruning plant stems, thus increasing waste. Dragon fruit stem powder contains cellulose which has the potential to be a suspending agent in ibuprofen suspension preparations. This study aims to obtain information about the effect of different concentrations of dragon fruit stem powder as a suspending agent on the physical characteristics of ibuprofen suspensions and to determine the concentration of dragon fruit stem powder as a suspending agent that can provide good physical characteristics of ibuprofen suspensions. Ibuprofen suspensions were made with different concentrations of dragon fruit stem powder, namely 5%; 7.5%; 10%. The suspension preparation was tested for physical characteristics including organoleptic tests, pH, viscosity, sedimentation ratio, and particle size. The test results were analyzed using a statistical approach using parametric and non-parametric tests with a 95% confidence level. The results showed that there was an effect of different concentrations of dragon fruit stem powder as a suspending agent on the physical characteristics of ibuprofen suspensions. The results of statistical analysis showed that there were significant differences (Sig.<0.05) in the physical characteristics of ibuprofen suspension preparations including: pH and viscosity, while particle size and sedimentation ratio were not significantly different (Sig.>0.05) in Formula II and Formula III. The concentration of 7.5% dragon fruit stem powder as a suspending agent in ibuprofen suspension was the concentration that provided the best physical characteristics.

Page 30 of 30 | Total Record : 291

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