cover
Contact Name
I Wayan Sudarsa
Contact Email
sudarsa@unud.ac.id
Phone
-
Journal Mail Official
globalpharmatechnology@gmail.com
Editorial Address
India
Location
Kota denpasar,
Bali
INDONESIA
Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
Lack of Association between Hypercholesterolemia and Obesity Status with the Gallstones type among Cholelithiasis Patients at Sanglah General Hospital, Bali, Indonesia Heru Sutanto Koerniawan
Journal of Global Pharma Technology Volume 11 Issue 04.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction: Gallstone disease is still one of the major health problems in the world. It is one of the most common diseases in developed countries associated with many factors. Increased total blood cholesterol, free cholesterol, LDL, triacylglycerol, obesity, and decreased HDL cholesterol levels also play an important role in the pathogenesis of gallstone formation. This study aimed to determine the relationship between hypercholesterolemia and obesity to types of gallstones. Methods: An observational cross-sectional study was conducted at Sanglah General Hospital from January-December 2017. The sample was obtained using consecutive sampling of patients with cholelithiasis that met inclusion and exclusion criteria. Data analysis was done with univariate and bivariate analysis using SPSS version 23 software. The confidence interval was set to 95% and p-value < 0.05 was considered statistically significant. Result: Twenty-six samples were included in this study. Majority of the sample was suffered from gall stone type cholesterol and was performed open cholecystectomy. There was no association found between gall stone type and obesity (p=0.618). In addition, recent findings also suggest no significant differences between gall stone type and total cholesterol status (p=0.211).Conclusion: There is no association between obesity and hypercholesterolemia with gall stone type in cholelithiasis patients.Keywords: Cholelithiasis, Gallstone, Hypercholesterolemia, Obesity.
Effect of Self Efficacy Training on Diet and Blood Glucose Compliance in Diabetes Type 2 Mellitus Patients Hariyono Hariyono
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Self-efficacy training is an effective way for people with diabetes mellitus to get improved blood glucose compliance and control. The purpose of this study was to analyze the effect of self-efficacy training on diet compliance and blood glucose. Methods: This study used a quasi-experimental pre-post-test with a control group. The population of this study was all Diabetes Mellitus patients in the Public Health Center area with 17 sample respondents for each group. The sampling technique was purposive sampling. The variables of this study were: self-efficacy training, diet compliance, and blood glucose. The way to collect data was by using questionnaires and laboratory examinations. Result:  The results showed that self efficacy training did not affect the adherence of diabetic patients in either the intervention group or the control group with the Wilcoxon test results showing the intervention group (p = 0.863 (p <0.05)), the control group (p = 0.677 (p < 0.05)) and the Mann-Whitney test (p = 0.909 (p> 0.05)). The second result showed that self-efficacy training had an effect on blood glucose in patients with Diabetes Mellitus in the intervention group but did not affect the control group, according to the Wilcoxon test results showed for the intervention group (p = 0.003 (p <0.05), the control group (p = 0.163 (p> 0.05) and the Mann-Whitney test (p = 0.080 (p> 0.05). Discussion: self-efficacy training can improve blood glucose control quite well, but still requires integration with other components related to the pillars of Diabetes Mellitus management. Self-efficacy training is not significant enough to improve the adherence of diabetic patients but with increased knowledge and behavior, it is hoped that they will be able to increase their motivation to support increased self-care abilities, change behavior and carry out activities to maintain glycemic control.Keyword: Self Efficacy Training, Diet Compliance, Blood Glucose, Glycemic Control, Diabetes Mellitus.
Study of the Psychosocial Aspects of Epileptic Patient Attending the Middle Euphrates Neurological Sciences Center in AL-Najaf AL-Ashraf Province in Iraq Salma KJ
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The findings of the present study indicated that the overall domains have an effect on patients with epilepsy among those domains social isolation which was the highest. Objectives: are to identify the demographic characteristics of the sample, also find out the impact of the epilepsy on patient psychosocial aspects, and Find out the relationship between the demographic characteristics of the patient and the impact of the epilepsy. Methodology: A descriptive Cross-sectional study was conducted on a non probability (purposive sampling) which consists of (100) patients with epilepsy who attending the Middle Euphrates Neurological Sciences Center in AL-Najaf AL-Ashraf Province, from September 16th 2016 to October 20th 2017.Results: The results of the study found that majority of participants are males and aged between (20-30) years old, most of them are married, high percentage of the sample was illiterate and regarding sample monthly income, it was found that patients were satisfied; age disease of onset found to be at (21-more) years old,  the majority them were non-smokers, the pathology of epilepsy is idiopathic more than symptomatic in clinical data. Finally there was no significant relationship between the overall patient’s psychosocial aspects and their clinical data also demographic data. Conclusion: The study concludes that social isolation is one of the psychosocial aspects that scored severs effect in many of the items, no significant relationship was found between the overall patient psychosocial aspects and the family and social support. Recommendations: Patients can be given more chances to share the health care providers with their experiences and all the issues related to the attack. It's better to provide the patients with an identification card clarifying some information about the particular patient.Keywords: Psychosocial aspects, Stigma, Epilepsy, Pathology of epilepsy.
Molecular Detection of Fungal Species in a Sample of Iraqi Patients with Meningitis Ahmed Sahib Abdulamir
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Infections of the central nervous system (CNS) with fungi can cause devastating consequences. Although, several fungi may result in infection of normal humans, most of them are opportunistic and influence immuno-compromised hosts. Invasion of the CNS with fungi can cause one or more the symptoms such as acute or chronic meningitis, abscesses or granuloma encephalitis, stroke, parenchymal brain, or myelopathy. Objective: To assess the frequency of fungal infection as causative agents of meningitis. Patients and methods: Two hundred patients with meningitis, who admitted to three hospitals (name hospitals) in Baghdad, were enrolled in this study from May 2016 to January 2017.The detection methods based on clinical and laboratory criteria and PCR using primers sequence for ITS gene for identification of fungus at species level. Results: The current study showed that, the percentage of aseptic meningitis among immune-compromised patients   was 31 samples. The age ranged between (1-78) years. The male to female ratio was 1:1.08. The prevalence of ITS gene was 15.5% detected by PCR, rRNA gene sequencing provides accurate identification information, with the best results obtained of ITS1, ITS4 sequencing. Candida albicans and Cryptococcus neoformans had the highest positive percentage among other species. Conclusion:  molecular technique by using PCR is sensitive and accurate tool for diagnosis fungal meningitis. ITS gene is important for detection of fungus in CSF sample. Candida albicans and Cryptococcus neoformans are most commen species caused fungal meningitis.Keywords: Cryptococcus, Candida, Aspergillus, molecular detection of fungal meningitis.
Evaluate the Effect of Biosynthesized Silver Nanoparticles on Wound Healing in Experimental Mice Neihaya H. Zaki
Journal of Global Pharma Technology Volume 11 Issue 07
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Biosynthesized silver nanoparticles showed a change in solution color from light yellow to dark brown after 24hr incubation. Results of Ag-NPs characterized by Scanning electron microscopy showed oval, rectangle particles and the average size is 35.1 nm. X-ray diffraction shows one high peak at 2ø (32.5°) as standard XRD data of nano-silver crystals. Antibacterial activity of Ag-Nps against pathogenic isolates of E. coli, P. aeruginosa, Klebsiella pneumoniae and Staph. aureus was shown as inhibition zones (11, 12, 14 and 11) mm respectively. There are no toxicity of Ag-Nps in treated mice, and no significant changes nor clinically significant changes observed in the body. Ag-Nps (10mM) showed significant reduction in incision wound for 7 days. Actions of Ag-Nps on wound healing in mice provided a new therapeutic direction for wound treatment in clinical apply. Keywords: Biosynthesis of Ag-Nps, E.coli, Antibacterial activity, Wound Healing.
Effects Mixture Powder of Black Rice, Red Beans and Moringa Leaves on Blood Glucose in Hyperglycemic Rats Lalu Juntra Utama
Journal of Global Pharma Technology Volume 12 Issue 09 (2020) Sept. 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction: The increase in blood sugar or hyperglycemia is a metabolic disorder known as diabetes mellitus and is associated with the rise of oxidative stress and complications in the vascular system. Further, it will cause alteration in carbohydrate and fat metabolism leads to a reduction of the antioxidant defense system. Black rice, red beans and moringa leaves contain oleic acid, butyric amino acid, antioxidants, phytic acid and arginine which can improve insulin sensitivity and blood glucose homeostatis. This study aims to identify the effect of mixture powder (black rice, red beans, and moringa leaves) based feeding against the blood glucose level in rats. Methods: The study was an experimental research with pre and post control group design. A total of 20 Sprague Dawley female rats were divided into four groups, namely standard feed (PS), 80% mixture powder feeding (PB8), 50% mixture powder feeding (PB5) and 20% mixture powder feeding (PB2). The mixture powder intervention was executed about 5% of body weight for 28 days. Fasting blood glucose was measured using the GOD-PAP method. The data obtained was conducted the statistical analysis using the Analysis of Variance (ANOVA) at a 95% confidence level. If it showed a significant effect on the response variable, then Duncan's Multiple Range Test would be conducted. Results: There were significant differences in fasting blood glucose among groups after the mixture powder intervention. The results revealed that after 28 days, mixture powder might lower the serum glucose concentration from 122.69 mg/dL to 97.70 mg/dL (20.37%) in the PB8 group and from 123.91 mg/dL to 113.28 mg/dL (8.58%) in the PB5 group, but vice versa, the blood glucose in the PS group, intervened by standard-based feeding increased by 5.73%. According to these results, mixture powder can be considered to reduce blood glucose in people with obesity and metabolic syndrome. Conclusion: The intervention of a mixture of black rice, red beans, and Moringa leaves may significantly influence the fasting blood glucose in rats. Keywords: Black rice, red beans, moringa leaves, fasting blood glucose
Antimicrobial Effect of the Crude Phenolic, Alkaloid and Terpenoid Compounds Extracts of Myrtus Communis L. against Human Gram-Negative Pathogenic Bacteria Ali Hussein Al-Marzoqi
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Objective: To reveal the effect of the crude phenol, alkaloid and torpedoed compounds extracts of Mitres Communes L. on some Human gram-negative Pathogenic Bacteria. Methods Antibacterial activities of the crude Phenol, Alkaloid and Torpedoed of medicinal plant were determined in vitro by agar well diffusion-method against some human pathogenic bacteria. Results obtained results showed that active compounds of Mitres Communes L. had wide spectrum antibacterial activity against gram- gram-negative bacteria Conclusion This study demonstrates that we can conclude that the effect of active compounds in same plant has different effect on different pathogenic organisms in different concentrations.Keywords: Antimicrobial, Myrtus Communis, L Pathogenic Bacteria, Gram-negative Bacteria.
Reduce Graphene Decorated with Iron Oxide/ Polymer Composite for Photo-Fenton Pollutants Dye Degradation Sara Abdul Karim Dawai
Journal of Global Pharma Technology Volume 11 Issue 09: (2019) September 2019
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The treatment processes for industrial wastewater contains organic pollutants and removal of heavy metal ions remain challenging. In this work,   photo Fenton reaction activity was used to degrade the organic pollutants by functional composite hydrogel. The hydrogel is made up of Fe3O4 particles, reduced graphene oxide (RGO) and polyacrylamide (PAM). It is prepared from rGO/Fe3O4 and by precipitation method, GO has been prepared from graphite by Hummers method. And exhibits the outstanding mechanical strength, Photo-Fenton activity by different decomposition data that were affected differently; pH, H2O2 concentration, dye concentration, temperature, irradiation time. The morphology of the composite and the average diameter was studied by Atomic Force Microscopy (AFM). The degradation of M.B dye by Fe3O4/rGO/PAM hydrogel composite was reached to 100% after 60 min under UV irradiation. Meanwhile, COD (Chemical Oxygen Demand) decreased to 21 mg/l after one hour's visible irradiation and became low (under range) after 2 hours. This study provides a new pathway to process the industrial wastewater of high consistence and difficult decomposition.Keywords: Photo- Fenton reaction, RGO/Fe3O4/PAM composite, Methylene Blue, COD.
Technical Factors Affecting to the Dried Mango (Mangifera Indica) Leaf Tea Production Nguyen Phuoc Minh
Journal of Global Pharma Technology Volume 10 Issue 08: (2018) August 2018
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Mango (Mangifera indica L.) was a juicy stone fruit belongs to the family of Anacardiaceae. Mango fruits were an important source of micronutrients, vitamins and other phytochemicals. Mango (Mangifera indica) leaf was used as astringent, refrigerant styptic, vulnerary and constipating. They are also useful in vitiated conditions of cough, hiccup, hyperdipsia, burning sensation, hemorrhages, haemoptysis, haemorrhoids, wounds, ulcers, diarrhoea, dysentery, pharyngopathy, scorpion string and stomachopathy. The ash of burnt leaves was useful in burns and scalds. The smoke from burning leaves was inhaled for relief of throat diseases. Tea is among the most consumed natural beverages worldwide due to its great benefits. Young leaves of mango (Mangifera indica) could be dried into herbal tea for aqueous extraction. Mangiferin is a major constituent of the leaves and stem bark of Mangifera indica. Objective of this search focused on investigating different processing aspects regarding to mango leaf tea while maintaining the most mangiferin content. Results were shown that the dried mango leaf would preserve mangiferin content by blanching the fresh mango leaf at 95oC, 4 seconds at size 2cm, then drying at 30oC by heat pump, and finally packing in PET/AL/PE bag at 4oC. By this approach, the dried mango leaf tea could be kept until 12 months without significant deterioration of mangiferin content.Keywords: Mango leaf, Mangiferin, Blanching, Drying, Packing, Tea.
Synthesis, Spectral Characterization, Theoretical Evaluation of New Cu (II) and Ni (II) Complexes of Flavon Omar H. Al-Obaidi
Journal of Global Pharma Technology Volume 11 Issue 03
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

A new series of Cu (II) and Ni (II) complexes with the Flavone ligand were prepared and spectroscopic method and elemental analysis verified their structures. All the prepared complexes have been identified by available spectroscopic tools (UV-Visible and IR) in addition the structure of complexes was characterized by  magnetic moments and molar conductance in DMSO solution .From the above of these studies and measurements suggest an tetrahedral geometry around Cu(II) and Ni(II). A theoretical treatment of the formation of complexes in the gas phase was studied; this was done using the Hyperchem-6 program for the Molecular mechanics and Semi-empirical calculations. Keywords: Flavone, Metal complexes, Synthesis, Spectral, Theoretical Evaluation.

Filter by Year

2010 2026


Filter By Issues
All Issue Volume 18 Issue 01 (2026) Jan. 2026 Volume 17 Issue 12 (2025) Dec. 2025 Volume 17 Issue 11 (2025) Nov.2025 Volume 17 Issue 10 (2025) Oct. 2025 Volume 17 Issue 04 (2025) April 2025 Volume 17 Issue 03 (2025) March 2025 Volume 17 Issue 02 (2025) Feb. 2025 Volume 17 Issue 01 (2025) Jan 2025 Volume 16 Issue 12 (2024) Dec. 2024 Volume 16 Issue 11 (2024) November 2024 Volume 16 Issue 10 (2024) October 2024 Volume 16 Issue 09 (2024) September 2024 Volume 16 Issue 08 (2024) August 2024 Volume 16 Issue 07 (2024) July 2024 Volume 16 Issue 06 (2024) June 2024 Volume 16 Issue 05 (2024) May 2024 Volume 16 Issue 04 (2024) April 2024 Volume 16 Issue 03 (2024) March 2024 Volume 16 Issue 02 (2024) February 2024 Volume 16 Issue 01 (2024) January 2024 Volume 14 Issue 05 (2022) May 2022 Volume 13 Issue 05 (2021) May 2021 Volume 13 Issue 04 (2021) April 2021 Volume 13 Issue 03 (2021) March 2021 Volume 13 Issue 02 (2021) Feb. 2021 Volume 13 Issue 01 (2021) Jan. 2021 Volume 12 Issue 12 (2020) Dec. 2020 Volume 12 Issue 11 (2020) Nov. 2020 Volume 12 Issue 10 (2020) Oct. 2020 Volume 12 Issue 09 (2020) Sept. 2020 Volume 12 Issue 08 (2020) Aug. 2020 Volume 12 Issue 07 (2020) July 2020 Volume 12 Issue 06 (2020) June 2020 Volume 12 Issue 05 (2020) May 2020 Volume 12 Issue 04 (2020) April 2020 Volume 12 Issue 03 (2020) March 2020 Volume 12 Issue 02 (2020) Feb. 2020 Volume 12 Issue 01 (2020) Jan. 2020 Volume 12 Issue 08 Volume 11 Issue 12 (2019) December 2019 Volume 11 Issue 11 (2019) November 2019 Volume 11 Issue 10 (2019) October 2019 Volume 11 Issue 09: (2019) September 2019 Volume 11 Issue 09 (2019) September 2019 Volume 11 Issue 08 (2019) Aug. 2019 Volume 11 Issue 07 (2019) July 2019 Volume 11 Issue 06 (2019) June 2019 Volume 11 Issue 05 (2019) May 2019 Volume 11 Issue 04 (2019) April 2019 Volume 11 Issue 03 (2019) March. 2019 Volume 11 Issue 02 (2019) Feb. 2019 Volume 11 Issue 01 (2019) Jan. 2019 Volume 11 Issue 2: 2019 Volume 10 Issue 12. Volume 11 Issue 6. Volume 10 Issue 12 (2018) December 2018 Volume 10 Issue 11 (2018) November 2018 Volume 10 Issue 10 (2018) October 2018 Volume 10 Issue 09: (2018) September 2018 Volume 10 Issue 08: (2018) August 2018 Volume 10 Issue 07: (2018) July 2018 Volume 10 Issue 06: (2018) June 2018 Volume 10 Issue 05: (2018) May2018 Volume 10 Issue 04: (2018) April 2018 Volume 10 Issue 02: (2018) Feb 2018 Volume 10 Issue 01: (2018) Jan. 2018 Volume 10 Issue 10: 2018 Volume 10 Issue 01 Volume 09 Issue 12 Volume 09 Issue 11 Volume 9 Issue 11 . Vol. 9 Issue 7 : 2017 Volume 9 Issue 10 Volume 09 Issue 09 Volume 09 Issue 08 Volume 9 Issue 07 Volume 09 Issue 05 Volume 09 Issue 04 Volume 09 Issue 03 Volume 09 Issue 02 Volume 08 Issue 11 Volume 08 Issue 07 Volume 08 Issue 06 Volume 08 Issue 05 Volume 08 Issue 04 Volume 08 Issue 03 Volume 08 Issue 02 Volume 08 Issue 01 Volume. 9 Issue 6 Volume 08 Issue 10: (2016) October 2016 Volume 08 Issue 09: (2016) September 2016 Volume 12 Issue 01 Volume 11 Issue 07 Volume 11 Issue 05. Volume 11 Issue 04. Volume 11 Issue 03 Volume 11 Issue 01. Volume 08 Issue 08 Volume 04 Issue 02: (2012) February 2012 Volume 03 Issue 06: (2011) June 2011 Volume 03 Issue 04: (2011) April 2011 Volume 02 Issue 10: (2010) Oct.2010 Volume 02 Issue 07: (2010) July 2010 Volume 02 Issue 05: (2010) May 2010 Volume 02 Issue 03: (2010) March 2010 More Issue