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Ahmed Abdillah
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INDONESIA
Journal of Advances in Medicine and Pharmaceutical Sciences
Published by Lamintang Education & Training Centre
ISSN : 2964268X     EISSN : 29634253     DOI : https://doi.org/10.36079/lamintang.jamaps-xxxx.xxx
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Medicine & Pharmacology Nursing Public Health
Journal of Advances in Medicine and Pharmaceutical Sciences (JAMAPS) scope are including but not limited to: ☛ Drug ☛ Chemistry ☛ Herbal Medicine ☛ Pharmaceutical Science ☛ General and Internal Medicine ☛ Pathology and Forensic Medicine ☛ Pharmacology, Toxicology and Pharmaceutics
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 38 Documents
 1   2   3   4 
Nursing Intervention in Handling Covid-19 Hypoxia Patients in the Isolation Room of Covid-19 Hospital Badaruddin Kasim Tanjung South Kalimantan Mohammad Basit Basit; Irwani Sunardi
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 2 No 1: May 2023
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0201.478

Abstract

Coronavirus 2019 (Covid-19) is an infectious disease caused by the acute respiratory syndrome of coronavirus 2 (Sars-CoV-2). Some complaints appear in patients who are confirmed to be covid-19, one of which is hypoxia, hypoxia is a condition of low levels of O2 contained in cells / tissues to below the physiological level. Nursing intervention activities against clients with hypoxia that nurses must do is to adjust the position of the client's body to reduce lung workload, teach correct breathing techniques, pay attention to the environment, collaboration on O2 administration. The research aims to find out nursing interventions in handling Covid-19 hypoxia patients in the Covid-19 Isolation Room of H. Badaruddin Kasim Tanjung Hospital. This study used qualitative methods with interview techniques that explained the implementation of nursing interventions with hypoxia clients with COVID-19 in the Isolation Room of Badaruddin Kasim Tanjung Hospital. Sampling using purposive sampling techniques. Data is analyzed through the results of interview recordings in the form of verbatim transcripts or descriptions of recordings in the form of written descriptions or narative texts. based on the results of the interview produced 6 sub themes, namely changing the position of semifowler patients in maximizing breathing, oxygen administration, monitor respiration status, observation of the respiratory department, monitor symptoms of hypoxia & happy hypoxia, and airway monitor.
The Effect of Banjar Language-Based Education on Hypertension Knowledge Level Raihana Rabiatul Adawiyah; Rian Tasalim; Bagus Rahmat Santoso
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 2 No 1: May 2023
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0201.487

Abstract

Uncontrolled hypertension makes the results worse. Knowledge of hypertension is a strong predictor of preventing complications. Increased knowledge can be provided through education. Language that is difficult for the public to understand when delivering information affects the success of education. So that the provision of education needs to pay attention to cultural aspects, one of which is the local language used by the community. This study aims to identify the respondent's characteristics of the history of hypertension, identify the influence before and after the provision of banjar language-based education on increasing knowledge of hypertension. The type of research design is Pre-Experimental one group pretest-posttest. The sample in this study amounted to 12 people. Sampling using total sampling technique. Data collection using the CAHE questionnaire with data analysis using the Wilcoxon statistical test. The results showed that before the intervention was given the level of knowledge was mostly not good 50.0% after being given the intervention there was an increase in knowledge of hypertension to 83.3%. Wilcoxon test results show that the value of = 0.002 < 0.05 so that H1 is accepted. The conclusion that nurses act as educators can make banjar language-based education one of the methods of health education in an effort to increase knowledge in hypertension sufferers
Relationship between Family Health Behavior with Improving Patient Functional Capacity Post Stroke in the Dwikora Area Ristika Julianty Singarimbun
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 2 No 1: May 2023
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0201.496

Abstract

Stroke is the biggest disease that causes paralysis of the limbs. Stroke patients require comprehensive treatment, including long-term recovery and rehabilitation efforts, even for the rest of the patient's life. The family plays an important role in this recovery phase, so from the start of treatment the family is expected to be involved in patient care. Family knowledge in the care of post-stroke patients is very important to be able accelerate the independence of post-stroke patients. This study aims to analyze the relationship between family health behavior and increasing the functional capacity of post-stroke patients in the Dwikora Area. The research was conducted in October 2021 - February 2022 the type of research is cross sectional. The study population was a family of post-stroke patients, totaling 30 people. The sampling technique used total sampling. Data collection in the study was carried out by distributing questionnaires directly to families. The statistical test used is the spearman rank. Based on the results of research conducted in the Dwikora Region, the majority of family knowledge in increasing the functional capacity of post-stroke patients was sufficient, 15 people 56.7%, both 13 people 43.3% and less than 2 people 6.7%. The attitude of the family in increasing functional capacity after stroke was a good majority of 15 people 50%, quite a number of 11 people 36.7% and less a number of 4 people 13.3%. Family action in increasing unctional capacity after stroke is sufficient for the majority of 17 people 56.7%, good for 11 people 36.7% and less for 2 people 6.7%, It is hoped that the family will carry out its role by increasing knowledge, attitudes and actions, so that the patient can independently carry out his own activities.
Relationship of Mother's Behavior with Basic Immunization at Public Health Center Pekanbaru City Aspiati; Julianty Singarimbun, Ristika
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 2 No 2: November 2023
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0202.528

Abstract

Immunization is a way to actively increase a person's immunity against an antigen, so when he is later exposed to a similar antigen, disease does not occur. The purpose of immunization is prevent the occurrence of certain diseases in group of people or even eliminate certain diseases from world, such as measles immunization. Mother's behavior about immunization form a positive attitude towards immunization activities. With the good knowledge, attitudes and actions that mother has, the awareness to immunize the baby will increase. The knowledge, attitudes and actions possessed by mother will raise the mother's confidence in health of baby and affect status of immunization in Indonesia. The research conducted is correlational quantitative data with a cross sectional design. The research was conducted at Pekanbaru City Health Center in August - December 2021. The study population was mothers who visited Pekanbaru City Health Center to immunize their babies, namely as many as 60 people. Sampling was done total sampling. The data collected in this research is of primary data which is collected directly from the respondents using a questionnaire. The results showed that mother's behavior regarding basic immunization was good for 20 people 33.3%, sufficient behavior for 13 people 21.7%, and poor behavior for 27 people 45.0%. From the results of study it is hoped that the Public Health Center can provide information about immunization to mothers who have babies and visit the Pekanbaru City Health Center to be more active and many mothers are enthusiastic about bringing their children to Integrated Healthcare Center every month.
Study of the Impact of Side Effects of Using Off-Label Drugs in Patients with Systemic Lupus Erythematosus on Health Costs Yuwindry, Iwan; Yusri; Tangkas, Hansel Hens
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 2 No 2: November 2023
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0202.529

Abstract

The main problem in conducting lupus treatment is that most drugs for the therapy provided have not been authorized so that they are still included in the class of off-label drugs for the treatment of lupus. The use of off-label drugs can carry the potential for side effects in Lupus patients which have an impact on increasing health costs. This study aims to determine the impact of side effects of using off-label drugs on health costs in lupus patients, as an integrated evaluation in seeking to improve the quality of life and ensure proper care in Lupus patients. This study was conducted using a cross-sectional method by means of a survey using the Naranjo Algorithm instrument (PESO Book) to determine the incidence rate of side effects that exist in LSE therapy using off-label drugs and calculate the health costs of lupus patients. The results showed that the most respondents were in adulthood (19 respondents or 47.5%), then the most respondents were female (37 respondents or 92.5%). Data on the incidence of side effects obtained the most respondents in the Probable category (most likely to occur ROM) of 14 respondents or 35%. In addition, data on health costs incurred by more respondents experienced an increase, namely 23 respondents or 57.5%. The research data shows the calculated r value is 0.3044 and the Sig (2-tailed) value is 0.000 with a confidence level (CI) of 0.05. The results of the analysis clearly show that there is a significant relationship between the side effects of using off-label drugs on the health costs of lupus patients, in this correlation there is a unidirectional relationship, where if the value of side effects experienced by respondents is high, the value of respondents' health costs is also high.
Effect of Guava Leaf Extract on Aeromonas Hydrophila Bacteria Pornpromlikit, Jamsuwan; Suchart, Komhom
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 2 No 2: November 2023
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0202.568

Abstract

Guava leaves (Psidium guajava L.) contain terpenoids, alkaloids, flavonoids, saponins and tannins, which are believed to have antibacterial properties against Aeromonas hydrophila. Aeromonas hydrophila bacteria are bacteria that are pathogenic and cause systemic disease. This research was conducted to determine the effectiveness of guava leaves in inhibiting Aeromonas hydrophil bacteria. The method used in the antibacterial activity test was the diffusion method using the paper disc technique. The results of the One-Way ANOVA test at the 5% level and followed by the Tukey test showed that the effective inhibitory concentration was 7900 ppm with a moderate antibacterial category.
The Hepatoprotective Effects of Phak Khom in Hepatitis Treatment Vanphanom, Sychareun; Chanthavongsa, Phimmasone; Phoudthavong, Sackdavong
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 2 No 2: November 2023
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0202.582

Abstract

This study investigated the hepatoprotective effects of Phak Khom (Andrographis paniculata) using in vitro and in vivo models. Phak Khom extract showed dose-dependent cytotoxicity on hepatocyte cells, significantly reducing cell viability at concentrations above 100 µg/mL. In addition, the extract showed a reduction in oxidative stress markers, with a 40% reduction in reactive oxygen species (ROS) and inhibition of pro-inflammatory cytokines (TNF-α and IL-6). In vivo, Phak Khom treatment in rats resulted in a significant reduction in liver enzyme levels (ALT and AST), indicating improved liver function. Histopathological analysis revealed decreased liver necrosis and fibrosis, while oxidative stress markers such as malondialdehyde (MDA) were decreased, and superoxide dismutase (SOD) activity was increased. Statistical analysis confirmed the efficacy of the extract at both low and high doses. These findings validate the traditional use of Phak Khom in liver-related disorders and support its potential as an adjunct therapy for hepatitis. However, further clinical studies, especially randomized controlled trials, are essential to confirm its safety and efficacy in humans, and to explore its synergy with conventional treatments.
Evaluating Gene Therapy and Immunotherapy for Cancer and Genetic Disorders Iliyas, Ahmad Mukhlis; Elkington, Albert; Wahab, Othman Abdul
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 2 No 2: November 2023
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0202.583

Abstract

Gene therapy and immunotherapy have emerged as revolutionary treatments in medicine, offering hope for previously untreatable diseases, particularly cancer and genetic disorders. This study aims to analyze the progress and challenges in gene therapy and immunotherapy in the US healthcare system during 2022 and 2023, with a focus on their effectiveness, barriers to implementation, and regulatory hurdles. The methodology used in this study is a descriptive qualitative approach, using literature reviews, case study analysis, and data from clinical trials at institutions such as the NIH and Mayo Clinic. The findings highlight significant advances in gene therapies such as CRISPR for genetic disorders and cancer treatment, as well as the success of CAR-T cell therapy in hematologic cancers. However, both therapies face challenges, including high treatment costs, regulatory delays, and limited accessibility. Despite these challenges, this study highlights the promising future of these therapies, with advances in gene editing and immunotherapy expected to expand their applications. Future research should focus on long-term safety and efficacy, cost reduction strategies, and improved delivery systems for both therapies. Addressing these gaps will be critical to the widespread adoption of gene therapy and immunotherapy in clinical practice.
Evaluating the Effectiveness of Thai Basil Extract in Managing Type 2 Diabetes Charoensup, Nathirat; Ruksiriwanich, Loryuenyong; Juruwan, Maneeton
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 3 No 2: November 2024
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0302.584

Abstract

This study investigated the potential of Ocimum basilicum var. thyrsiflora (Thai basil) extract as a natural adjunct therapy for the management of type 2 diabetes. The increasing prevalence of diabetes globally and the limitations of conventional therapies require alternative approaches, especially in regions where Thai basil is culturally accepted. The objective was to evaluate the effects of Thai basil on blood glucose levels and glycemic control in patients with type 2 diabetes. A randomized controlled trial was conducted in 2024 with 200 participants, aged 30–65 years, diagnosed with type 2 diabetes. Participants were assigned to either the Thai basil extract group (500 mg daily) or the placebo group, with clinical data collected at baseline, mid-intervention, and post-intervention. Findings showed that the intervention group experienced significant reductions in fasting blood glucose and HbA1c levels, indicating improved long-term glycemic control. In addition, lipid profiles, including cholesterol and triglyceride levels, were positively affected. However, no significant weight loss was observed. This review highlights the therapeutic potential of Thai basil bioactive compounds, including flavonoids and essential oils, which have antioxidant, anti-inflammatory, and antidiabetic properties. Limitations such as sample size and study duration are noted, indicating the need for further studies with larger, more diverse populations and longer duration. Future studies should explore the optimal dosage, formulation, and long-term effects of Thai basil. This study supports the inclusion of Thai basil in diabetes care, especially in regions where basil is widely available and culturally accepted.
Cissus quadrangularis in Bone Healing and Oxidative Stress Charoensup, Nathirat; Sangthong, Kittisak; Kongcharoen, Watis
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 3 No 1: May 2024
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0301.585

Abstract

Cissus quadrangularis is a plant known for its traditional use in bone healing, has shown potential in modern pharmacological applications due to its bioactive compounds. This study investigates the therapeutic effects of Cissus quadrangularis extract on bone healing, antioxidant activity, and gastric protection. The primary objective was to evaluate its efficacy in accelerating bone regeneration, mitigating oxidative stress, and protecting the gastric mucosa from NSAID-induced damage. The methodology involved a series of in vivo experiments using rats, with treatment groups receiving the extract and control groups given a placebo. Bone healing was assessed radiographically, antioxidant activity was measured using the DPPH assay and SOD enzyme activity, and gastric protection was evaluated by counting gastric lesions. The findings revealed a 40% improvement in bone healing, a 25% increase in SOD activity, and a 60% reduction in gastric lesions in the treatment group compared to controls. These results suggest that Cissus quadrangularis has significant potential as a natural remedy for bone fractures, oxidative stress, and gastric ulcers. Future research should focus on human clinical trials, molecular mechanisms, and long-term safety to support its broader medical application.

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