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INDONESIA
Indonesian Journal of Pharmacy and Natural Product
Published by Universitas Ngudi Waluyo
ISSN : 26563215     EISSN : 26156903     DOI : 10.35473
Core Subject : Health,
Medicine & Pharmacology
This journal is aimed as promoting principled approach to research on pharmacy that covers a broad range of topics engaging a good relationship in theoretical and practical. This journal covers: Pharmacology Pharmacognosy Analytical Chemistry Pharmaceutical Technology Social and Management Pharmacy
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 144 Documents
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Evaluasi Mutu Fisik, Stabilitas Mekanik dan Aktivitas Antioksidan Hand and Body Lotion Ekstrak Labu Kuning (Cucurbita moschata D.): Evaluation of Physical Quality, Mechanical Stability and Antioxidant Activity of Pumpkin Extract Hand and Body Lotion (Cucurbita moschata D.) Anasthasia Pujiastuti; Silva Hati Nurani
Indonesian Journal of Pharmacy and Natural Product Vol. 6 No. 01 (2023): Indonesian Journal of Pharmacy and Natural Product
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (368.704 KB) | DOI: 10.35473/ijpnp.v6i01.2235

Abstract

Damage to the skin can be caused by free radicals that come from sun exposure. Skin needs antioxidants to neutralize free radicals. Plants that have natural antioxidant power include pumpkin (Cucurbita moschata D.) which contains flavonoids. The purpose of this study was to evaluate the physical quality and mechanical stability of hand and body lotion preparations of pumpkin extract and antioxidant activity in the category of inhibitory concentration value (IC50). The laboratory research method used is the experimental method. The preparations were made in three formulas with different extract concentrations, namely 2,2%, 3,2% and 4,2%. Antioxidant activity test was carried out using the ABTS method. The results of the preparation evaluation were the value of viscosity (9.367-20.173 cP), pH 7, emulsion type (O/W), spreadability (4,5-7,7 cm), adhesion power (2,567-4,667 seconds), protection power (2,933 – 3,807 seconds) and in the mechanical stability test did not experience phase separation. The IC50 value of pumpkin extract obtained a value of 67,07 ppm (strong), formula I 84,05 ppm (strong), formula II 73,96 (strong), formula III 68,5 ppm (strong). Pumpkin extract hand and body lotion has good physical quality and mechanical stability and has strong antioxidant activity. ABSTRAK Kerusakan pada kulit dapat disebabkan karena adanya radikal bebas yang bersumber dari paparan sinar matahari. Kulit membutuhkan antioksidan untuk menetralkan radikal bebas. Tanaman yang mempunyai daya antioksidan alami antara lain labu kuning (Cucurbita moschata D.) dengan kandungan flavonoid. Tujuan penelitian ini yaitu untuk melakukan evaluasi mutu fisik dan stabilitas mekanik sediaan hand and body lotion ekstrak labu kuning serta aktivitas antioksidan dalam kategori nilai inhibitory concentration (IC50). Metode penelitian yang digunakan yaitu metode eksperimental laboratorium. Sediaan dibuat dalam tiga formula dengan perbedaan konsentrasi ekstrak yaitu 2,2%, 3,2% dan 4,2%. Uji aktivitas antioksidan dilakukan menggunakan metode ABTS. Hasil evaluasi sediaan yaitu nilai viskositas (9.367-20.173 cP), pH 7, tipe emulsi (M/A), daya sebar (4,5-7,7 cm), daya lekat (2,567-4,667 detik), daya proteksi (2,933-3,807 detik) dan pada uji stabilitas mekanik tidak mengalami pemisahan fase. Nilai IC50 ekstrak labu kuning diperoleh nilai 67,07 ppm (kuat), formula I  84,05 ppm (kuat), formula II 73,96 (kuat), formula III 68,5 ppm (kuat). Hand and body lotion ekstrak labu kuning memiliki mutu fisik dan stabilitas mekanik yang baik serta mempunyai aktivitas antioksidan dengan kategori kuat.
Analisis Pengaruh Edukasi Melalui Media Video terhadap Tingkat Pengetahuan Pasien Diabetes Melitus Tentang Perawatan Kaki di Puskesmas: Analysis of The Influence of Education Through Video Media on The Level of Knowledge of Diabetes Mellitus Patients About Foot Care at Puskesmas Almira Sekar Octaviana; Anita Kumala Hati
Indonesian Journal of Pharmacy and Natural Product Vol. 6 No. 02 (2023): Indonesian Journal of Pharmacy and Natural Product
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ijpnp.v6i02.2267

Abstract

Video media is effectively used as an effort to increase one's knowledge of information, media can show images that can move and have sound. The purpose of this study was to analyze the effectiveness of education about foot care using video on the level of knowledge of DM patients. This study used quasy-experimental design, pretest and posttest with control group, as many as 30 samples at Bawen Health Center and 30 samples at Suruh Health Center, which were taken by total sampling technique. Data were analyzed with the Wilcoxon test and Mann-Whitney with a 95% confidence level. The results of this study showed that most DM patients aged 56-65 years, with 12 men and 48 women. The results of the Wilcoxon test before and after in the treatment group were 0,000 which means that there was a significant difference after being given educational videos, and for the control group was 1,000 which means there was no significant difference. The results of the Mann-Whitney test before being given an educational video was 0.957 which means that there was no significant difference between the treatment and control groups, while after being given an educational video was 0.000 which means that there was a significant difference between the treatment and control groups. Providing education with video had been significantly increased foot care knowledge in type 2 DM patients. ABSTRAK Media video dapat membantu meningkatkan pengetahuan seseorang tentang informasi karena memiliki gambar bergerak dan suara. Tujuan penelitian ini yaitu untuk menganalisis efektivitas edukasi tentang perawatan kaki terhadap tingkat pengetahuan pasien DM. Penelitian ini menggunakan quasy-experimental design, pretest and posttest with control group, sebanyak 30 sampel di Puskesmas Bawen dan 30 sampel di Puskesmas Suruh, yang diambil dengan teknik total sampling. Data dianalisis dengan uji Wilcoxon dan Mann-Whitney dengan taraf kepercayaan 95%. Hasil penelitian ini menunjukkan pasien DM paling banyak usia 56-65 tahun, dengan jenis kelamin laki-laki 12 orang dan perempuan 48 orang. Hasil Uji Wilcoxon sebelum dan sesudah pada kelompok perlakuan didapatkan (0.000) artinya terdapat perbedaan yang signifikan setelah diberi video edukasi, dan pada kelompok kontrol didapatkan (1.000) artinya tidak terdapat perbedaan yang signifikan. Hasil Uji Mann-Whitney sebelum diberi video edukasi didapatkan (0.957) artinya tidak terdapat perbedaan yang signifikan antara kelompok perlakuan dan kontrol, sedangkan sesudah diberi video edukasi didapatkan (0.000) artinya terdapat perbedaan yang signifikan antara kelompok perlakuan dan kontrol. Pemberian edukasi dengan media video secara signifikan meningkatkan pengetahuan perawatan kaki pada pasien DM tipe 2.
Hubungan Tingkat Pengetahuan, Kepatuhan Minum Obat, dan Kadar Gula Darah Puasa Pasien Diabetes Melitus di Puskesmas X Kabupaten Batang: Correlation Between Level Of Knowledge, Medication Adherence, and Fasting Blood Glucose Levels Among Diabetes Mellitus Patients at Community Health Center X Batang Regency Ramadhani, Asna Fania; Hati, Anita Kumala
Indonesian Journal of Pharmacy and Natural Product Vol. 7 No. 01 (2024): Indonesian Journal of Pharmacy and Natural Product
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ijpnp.v7i01.2282

Abstract

Medication adherence is one of the factors supporting the control of clinical parameters in patients with diabetes mellitus (DM). Medication adherence is influenced by disease conditions, education, knowledge, medication, age, perceptions, and beliefs. This study aims to analyze the relationship between education level and level of knowledge with medication adherence and control of fasting blood glucose levels (FBG) in DM patients. The study was a descriptive correlative analytic with a cross-sectional approach including 47 respondents using a total sampling technique from X Public Health Center. The data was collected by DKQ-24 questionnaire, MARS-5 questionnaire, GDP inspection results with documentation. The data was analyzed using Spearman-rank. The results of the study with the highest respondent characteristics were female (53.2%), entrepreneurial work (55.3%), junior high school education level (36.2%), good level of knowledge (46.8%), high compliance level ( 66%) and controlled fasting blood sugar levels (53.2%). The relationship between the level of knowledge and the level of medication adherence is in the strong relationship category (coefficient correlation = 0.562). The relationship between the level of medication adherence and FBG levels is classified as a very strong relationship (coefficient correlation=0.766). There is a strong relationship between education level and knowledge level to medication adherence in patients with diabetes mellitus at X Public Health Center, Batang Regency   ABSTRAK Kepatuhan minum obat merupakan salah satu faktor pendukung kendali parameter klinis pasien diabetes melitus (DM). Kondisi penyakit, tingkat pendidikan, pengetahuan, obat, usia, persepsi dan keyakinan pasien dapat mempengaruhi kepatuhan minum obat. Penelitian ini hendak menganalisa hubungan tingkat pengetahuan dengan kepatuhan minum obat dan hubungan kepatuhan minum obat dengan kendali kadar gula darah puasa (GDP) pasien DM. Penelitian ini dilakukan di Puskesmas X Kabupaten Batang. Desain penelitian ini adalah deskriptif korelatif pendekatan cross sectional. Responden yang terlibat dalam penelitian ini sejumlah 47 pasien yang diperoleh dengan teknik total sampling. Instrumen pengukuran tingkat pengetahuan menggunakan kuesioner DKQ-24, kepatuhan minum obat menggunakan kuesioner MARS-5, dan hasil pemeriksaan GDP. Analisis data menggunakan uji spearman- rank. Hasil menunjukkan responden yang terlibat dalam penelitian ini paling banyak berjenis kelamin perempuan (53,2%), pekerjaan responden paling banyak sebagai wirausaha (55,3%), mayoritas responden memiliki tingkat pengetahuan baik (46,8%) dan tingkat kepatuhan tinggi (66%), serta responden dengan kadar gula darah puasa yang terkontrol sebesar 53,2%. Hubungan tingkat pengetahuan dengan tingkat kepatuhan minum obat tergolong kategori kuat (koefisien korelasi = 0,562). Hubungan tingkat kepatuhan minum obat dengan kadar GDP tergolong kategori sangat kuat (koefisien korelasi = 0,766). Terdapat hubungan tingkat pengetahuan dengan kepatuhan minum obat dan hubungan kepatuhan minum obat dengan kadar GDP pada pasien diabetes melitus di Puskesmas X Kabupaten Batang dengan korelasi kuat.
Tepung Tapioka, Kentang, dan Jagung sebagai Purifikasi Minyak Goreng Bekas (Kajian Kadar Malondealdehid, Asam Lemak Bebas, dan Tingkat Kekeruhan): Tapioca, Potato, and Corn Starch as Purifying Agent of Used Cooking Oil (Study Of Malondialdehyde, Free Fatty Acids and Turbidity Levels) Susilo, Jatmiko; Siswanta Jaka Purnama; Salsabiela Dwiyudrisa Suyudi
Indonesian Journal of Pharmacy and Natural Product Vol. 6 No. 02 (2023): Indonesian Journal of Pharmacy and Natural Product
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ijpnp.v6i02.2294

Abstract

Consumption of repeating heated cooking oil, and its fumes cause a high incidence of genotoxic, mutagenic, tumorogenic, and various types of cancer. Amylose affects oil absorption by interfering with the structural evolution of starch or by interacting directly with lipids during frying. This study aimed to analyze the effect of tapioca, potato, and corn flour on improving the quality of used cooking oil by studying malondialdehyde (MDA) levels. Free fatty acids (ALB) and turbidity levels. Experimental research with pre-test and post-test designs, using tapioca, potatoes and corn fluor (5; 10 and 20 g) as purifiers in 100 ml of used cooking oil. Flour frying is carried out at a temperature of 160-165 °C for 5 minutes. MDA levels were determined using the spectrophotometric TBARs method at λmax: 532 nm, alkalimetry to determine ALB levels, while the turbidity level was spectrophotometric at λmax: 448 nm with comparison to fresh cooking oil. The three types of flour were able to reduce levels of MDA, ALB, and turbidity (p<0.001). The type of flour decreased (p>0.5), while the amount of flour decreased MDA and turbidity levels (p<0.0001), but ALB levels (p>0.5). This research has proven that flour (tapioca, wheat and corn) can improve the quality of used cooking oil by reducing MDA, ALB and turbidity levels. ABSTRAK Konsumsi minyak goreng yang dipanaskan berulang kali dan asapnya menyebabkan tingginya insiden genotoksik, mutagenik, tumorogenik, dan berbagai jenis kanker. Amilosa mempengaruhi penyerapan minyak dengan mengganggu evolusi struktural amilum atau dengan berinteraksi langsung dengan lipid selama penggorengan Penelitian bertujuan untuk menganalisis pengaruh tepung tapioka, kentang, dan jagung terhadap peningkatan kualitas minyak bekas goreng dengan kajian kadar malondealdehid (MDA). Asam lemak bebas (ALB) dan tingkat kekeruhan. Penelitian eksperimental dengan desain pre-test dan post-test, menggunakan tepung tapioka, kentang dan jagung (5 ; 10 dan 20 g) sebagai pemurni dalam 100 ml minyak bekas goreng. Penggorengan tepung dilakukan pada suhu 160-165 °C selama 5 menit. Kadar MDA ditetapkan menggunakan metoda TBARs spektroforometri pada λmaks:532 nm, alkalimetri untuk menetapkan kadar ALB, sedangkan tingkat kekeruhan dengan spektrofotometri pada λmaks:448 nm dengan pembanding minyak goreng baru. Hasil penelitian ini adalah ketiga jenis tepung mampu menurunkan kadar MDA, ALB, dan kekeruhan (p<0,001). Jenis tepung mengalami penurunan (p>0,5), sedangkan jumlah tepung mengalami penurunan kadar MDA dan kekeruhan (p<0,0001), tetapi kadar ALB (p>0,5). Penelitian ini telah membuktikan tepung (tapioka, terigu, dan jagung) mampu meningkatkan kualitas minyak goreng bekas dengan menurunkan kadar MDA, ALB dan tingkat kekeruhan.
Evaluasi Sistem Penyimpanan Sediaan Farmasi Berdasarkan Standar Pelayanan Kefarmasian Rumah Sakit dan Syariat Islam di RSI Sultan Agung Semarang: Evaluation of the Pharmaceutical Preparation Storage System Based on Hospital Pharmaceutical Service Standards and Islamic Sharia at RSI Sultan Agung Semarang Zulfitri; Yanna Sagitasari; Atina Hussana
Indonesian Journal of Pharmacy and Natural Product Vol. 7 No. 01 (2024): Indonesian Journal of Pharmacy and Natural Product
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ijpnp.v7i01.2301

Abstract

Pharmaceutical services are the main maintenance services for a hospital. RSI Sultan Agung Semarang is a hospital that has been certified according to Islamic law and has pharmaceutical installations, especially pharmaceutical logistics, which are responsible for pharmaceutical preparations, medical devices and consumable medical materials to avoid damage and maintain the quality of pharmaceutical preparations. The aim of this research is to determine the harmony of the spatial layout and storage system for pharmaceutical preparations at the Pharmacy Logistics RSI Sultan Agung Semarang based on the Standard Instructions for Pharmaceutical Services in Hospitals and Islamic Sharia. This descriptive observational research method uses prospective data collection techniques in the February-March period through interviews with the pharmacist in charge of the pharmacy warehouse. The data taken includes the spatial layout and storage system for pharmaceutical preparations and the data acquisition score is calculated using the Guttman scale. The results of data analyzed descriptively show that there is a balance in the spatial planning checklist of 94.75% (very good) and a storage system of 90.91% (very good) and conformity based on Islamic law of 25% (not good). The storage system for pharmaceutical preparations in pharmaceutical logistics at RSI Sultan Agung Semarang is based on pharmaceutical service standards in hospitals and Islamic law with an average percentage of 70.22% in the (good) category.   ABSTRAK Pelayanan kefarmasian merupakan pelayanan penunjang utama bagi suatu rumah sakit. RSI Sultan Agung Semarang merupakan rumah sakit yang telah tersertifikasi secara syariat Islam dan memiliki Instalasi farmasi khususnya farmasi logistik yang bertanggung jawab terhadap sediaan farmasi, alat kesehatan, dan bahan medis habis pakai agar tetap terhindar dari kerusakan serta menjaga mutu sediaan farmasi. Tujuan penelitian ini adalah untuk mengetahui kesesuaian tata ruang dan sistem penyimpanan sediaan farmasi di logistik farmasi RSI Sultan Agung Semarang berdasarkan Petunjuk Standar Pelayanan Kefarmasian di Rumah Sakit dan Syariat Islam. Metode penelitian observasional deskriptif ini menggunakan teknik pengumpulan data secara prospektif pada periode Februari-Maret melalui wawancara kepada Apoteker Penanggung Jawab logistik farmasi. Data yang diambil meliputi tata ruang dan sistem penyimpanan sediaan farmasi. Skor perolehan data dihitung menggunakan skala guttman. Hasil data yang diperoleh dianalisis secara deskriptif menunjukkan bahwa terdapat kesesuaian ceklist tata ruang sebesar 94,75 % (sangat baik) dan sistem penyimpanan sebesar 90,91 % (sangat baik) serta kesesuaian berdasarkan syariat Islam sebesar 25 % (kurang baik). Sistem penyimpanan sediaan farmasi di logistik farmasi di RSI Sultan Agung Semarang berdasarkan standar pelayanan kefarmasian di Rumah Sakit dan syariat Islam dengan hasil rata-rata presentase sebesar 70,22 % masuk dalam kategori (baik).
Evaluasi Penerapan Pelayanan Konseling Berbasis Syariah terhadap Kepuasan Pasien di Puskesmas Srondol Semarang : Evaluation of the Implementation of Syariah-Based Counseling Services on Patient Satisfaction at the Srondol Semarang Community Health Center Yuyun Darma Ayu Ningrum; Anik Moeljani; Desi Renianti
Indonesian Journal of Pharmacy and Natural Product Vol. 6 No. 02 (2023): Indonesian Journal of Pharmacy and Natural Product
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ijpnp.v6i02.2304

Abstract

Patient satisfaction is an assessment of the good and bad quality of health services received by patients. Patients will feel satisfied if the performance of the health services they receive is the same as or exceeds their expectations. The level of patient satisfaction is very important and is closely related to the level of patient return visits so that this can be used as an indicator of the quality of health services. This study aims to determine the application of sharia-based counseling services to patient satisfaction at the Srondol Semarang health center. The method used in this research is an observational method, carried out by collecting data on the research object by administering a questionnaire stating patient satisfaction with sharia-based counseling services for Srondol Health Center patients. The results of the validity test produce an r value for each statement > 0.361 (valid). The reliability test was carried out using the Cronbach Alpha test> 0.6 (reliable) for each questionnaire item. The results of testing using a questionnaire obtained an average result of 47.6% satisfied patients, 40.67% very satisfied and 11.67% dissatisfied with sharia-based counseling services at the Srondol Health Center. Evaluation of the implementation of sharia-based counseling services on patient satisfaction at the Srondol Semarang Community Health Center is based on Islamic law. ABSTRAK Kepuasan pasien merupakan penilaian terhadap baik buruknya kualitas pelayanan kesehatan yang diterima oleh pasien. Pasien akan merasa puas apabila kinerja pelayanan kesehatan yang diperoleh sama atau melebihi harapannya. Tingkat kepuasan pasien sangat penting dan berhubungan erat dengan tingkat kunjungan kembali pasien sehingga hal ini dapat digunakan sebagai indikator terhadap kualitas pelayanan kesehatan. Penelitian ini bertujuan untuk mengetahui penerapan pelayanan konseling berbasis syariah terhadap kepuasan pasien di puskesmas Srondol Semarang. Metode yang digunakan pada penelitian ini adalah metode observasional, dilakukan dengan pengumpulan data terhadap objek penelitian dengan cara memberikan kuesioner pernyataan kepuasan pasien terhadap pelayanan konseling berbasis syariah pasien Puskesmas Srondol. Hasil uji validitas menghasilkan nilai r untuk masing-masing pernyataan > 0,361 (valid). Tes reliabilitas dilakukan dengan menggunakan uji Cronbach Alpha >0,6 (reliabel) untuk masing-masing item kuesioner. Hasil pengujian menggunakan kuesioner didapatkan hasil rata-rata pasien merasa puas sebanyak 47,6%, sangat puas 40,67% dan tidak puas sebanyak 11,67% terhadap pelayanan konseling berbasis syariah di puskesmas srondol. Evaluasi penerapan pelayanan konseling berbasis syariah terhadap kepuasan pasien di Puskesmas Srondol Semarang telah dilandasi syariat islam. 
Evaluasi Sistem Penyimpanan Sediaan Farmasi Berdasarkan Standar Pelayanan Kefarmasian Rumah Sakit dan Syariat Islam di RSI Sultan Agung Semarang : Evaluation of the Pharmaceutical Preparation Storage System Based on Hospital Pharmaceutical Service Standards and Islamic Sharia at RSI Sultan Agung Semarang Zulfitri; Yanna Sagitasari; Atina Hussana
Indonesian Journal of Pharmacy and Natural Product Vol. 6 No. 02 (2023): Indonesian Journal of Pharmacy and Natural Product
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ijpnp.v6i02.2305

Abstract

Pharmaceutical services are the main maintenance services for a hospital. RSI Sultan Agung Semarang is a hospital that has been certified according to Islamic law and has pharmaceutical installations, especially pharmaceutical logistics, which are responsible for pharmaceutical preparations, medical devices and consumable medical materials to avoid damage and maintain the quality of pharmaceutical preparations. The aim of this research is to determine the harmony of the spatial layout and storage system for pharmaceutical preparations at the Pharmacy Logistics RSI Sultan Agung Semarang based on the Standard Instructions for Pharmaceutical Services in Hospitals and Islamic Sharia. This descriptive observational research method uses prospective data collection techniques in the February-March period through interviews with the pharmacist in charge of the pharmacy warehouse. The data taken includes the spatial layout and storage system for pharmaceutical preparations and the data acquisition score is calculated using the Guttman scale. The results of data analyzed descriptively show that there is a balance in the spatial planning checklist of 94.75% (very good) and a storage system of 90.91% (very good) and conformity based on Islamic law of 25% (not good). The storage system for pharmaceutical preparations in pharmaceutical logistics at RSI Sultan Agung Semarang is based on pharmaceutical service standards in hospitals and Islamic law with an average percentage of 70.22% in the (good) category. ABSTRAK Pelayanan kefarmasian merupakan pelayanan penunjang utama bagi suatu rumah sakit. RSI Sultan Agung Semarang merupakan rumah sakit yang telah tersertifikasi secara syariat Islam dan memiliki Instalasi farmasi khususnya farmasi logistik yang bertanggung jawab terhadap sediaan farmasi, alat kesehatan, dan bahan medis habis pakai agar tetap terhindar dari kerusakan serta menjaga mutu sediaan farmasi. Tujuan penelitian ini adalah untuk mengetahui kesesuaian tata ruang dan sistem penyimpanan sediaan farmasi di logistik farmasi RSI Sultan Agung Semarang berdasarkan Petunjuk Standar Pelayanan Kefarmasian di Rumah Sakit dan Syariat Islam. Metode penelitian observasional deskriptif ini menggunakan teknik pengumpulan data secara prospektif pada periode Februari-Maret melalui wawancara kepada Apoteker Penanggung Jawab logistik farmasi. Data yang diambil meliputi tata ruang dan sistem penyimpanan sediaan farmasi. Skor perolehan data dihitung menggunakan skala guttman. Hasil data yang diperoleh dianalisis secara deskriptif menunjukkan bahwa terdapat kesesuaian ceklist tata ruang sebesar 94,75 % (sangat baik) dan sistem penyimpanan sebesar 90,91 % (sangat baik) serta kesesuaian berdasarkan syariat Islam sebesar 25 % (kurang baik). Sistem penyimpanan sediaan farmasi di logistik farmasi di RSI Sultan Agung Semarang berdasarkan standar pelayanan kefarmasian di Rumah Sakit dan syariat Islam dengan hasil rata-rata presentase sebesar 70,22 % masuk dalam kategori (baik).
Analisis Efektivitas Biaya Penggunaan Metformin dan Metformin- Glimepirid Pada Pasien Diabetes Melitus Tipe 2 di Dua Puskesmas Kulon Progo Yogyakarta: Mellitus Patients at the Two Public Health Centers Kulon Progo Yogyakarta Cost-Effectiveness Analysis of Metformin and Metformin-Glimepiride Use In Type 2 Diabetes Lastrie, Astry; Dyah Aryani Perwitasar; Woro Supadmi
Indonesian Journal of Pharmacy and Natural Product Vol. 6 No. 02 (2023): Indonesian Journal of Pharmacy and Natural Product
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ijpnp.v6i02.2306

Abstract

Cost-effectiveness analysis (CEA) is a pharmacoeconomic method that is described in terms of cost-effectiveness ratios in order to assist decision making in selecting drugs that are effective in terms of benefits and costs. The purpose of this study was to determine the effectiveness of the use of metformin and metformin-glimepiride in type 2 DM patients at the 2 Public Health Centers Kulon Progo Yogyakarta. This analytical descriptive observational research employed a retrospective cohort design. The analysis was carried out by comparing the total costs incurred with the effectiveness of the therapeutic outcomes were obtained. The cost-effectiveness analysis of therapy used the Average Cost Effectiveness Ratio (ACER) and Incremental Cost Effectiveness Ratio (ICER) calculation methods. The results showed that the therapeutic effectiveness of the therapy used metformin and metformin-glimepiride in 12 patients (80%) and 30 patients (66.67%) respectively. The average cost of drugs from each group were Rp 9,072 and Rp 18,634. The ACER values were Rp 113.4 and Rp 279.5, respectively. The ICER value was obtained Rp – 717,3. The results of the chi-square test showed that there was no relationship between the type of therapy and the effectiveness of therapy (P=0.329) and the value of RR 2 with confidence interval (CI) 95% about 0.489-8.182. It can be concluded that based on the calculation of the ACER and ICER analysis methods, metformin therapy is more cost effective than metformin-glimepiride. There was no significant relationship between the type of therapy with the effectiveness of therapy. ABSTRAK Analisis efektivitas biaya (CEA) merupakan metode farmakoekonomi yang digambarkan dalam rasio biaya-efektivitas agar dapat membantu pengambilan keputusan dalam memilih obat yang efektif secara manfaat dan biaya. Tujuan dari penelitian ini untuk mengetahui efektivitas biaya penggunaan metformin dan metformin-glimepirid pada pasien DM tipe 2 di 2 Puskesmas Kulon Progo Yogyakarta. Metode penelitian yaitu observasional deskriptif menggunakan desain kohort retrospektif. Analisis dilakukan dengan membandingkan total biaya yang dikeluarkan dengan efektivitas outcome terapi yang didapatkan. Analisis efektivitas biaya terapi menggunakan metode perhitungan Average Cost Effectiveness (ACER) dan Incremental Cost Effectiveness Ratio (ICER). Hasil penelitian menunjukkan efektivitas terapi penggunaan metformin dan metformin-glimepirid secara berurutan sebanyak 12 pasien (80%) dan 30 pasien (66,67%). Biaya rata-rata obat dari masing- masing kelompok adalah Rp 9.072,- dan Rp 18.634,-. Nilai ACER secara berurut adalah Rp 113,4 dan Rp 279,5. Nilai ICER diperoleh Rp - 717,3. Hasil uji chi-square menunjukkan tidak ada hubungan antara jenis terapi dengan efektivitas terapi (P = 0,329) dan nilai RR 2 dengan konviden interval 95% berkisar antara 0,489-8,182. Dapat disimpulkan bahwa berdasarkan perhitungan metode analisis ACER dan ICER, terapi metformin lebih cost effective dibandingkan metformin-glimepirid. Tidak terdapat hubungan signifikan antara jenis terapi dengan efektivitas terapi.
Evaluasi Ketepatan Penggunaan Obat Antihipertensi di Puskesmas Boyolali 1 Periode Januari - Juni 2022: Evaluation of the Appropriate Use of Antihypertensive Drugs at the Boyolali 1 Health Center for the Period January - June 2022 Dwi Jayanti Isnasari; Risma Sakti Pambudi; Khotimatul Khusna
Indonesian Journal of Pharmacy and Natural Product Vol. 6 No. 02 (2023): Indonesian Journal of Pharmacy and Natural Product
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ijpnp.v6i02.2319

Abstract

Hypertension is better known as cardiovascular or heart disease. Hypertension is still a disease whose prevalence rate is increasing. The problem that is often found in the management of hypertension is the inappropriate use of antihypertensive drugs and dosages.This research was conducted to determine the accuracy of using the right antihypertensive drugs including the right drugs and dosages at the Boyolali 1 Health Center for the period January - June 2022. This research is a study that uses a retrospective descriptive research design by looking at the medical record data of hypertensive patients. The sample in this study were patients with a diagnosis of hypertension in the January-June 2022 period at the Boyolali 1 Public Health Center who fit the inclusion and exclusion criteria for a total of 102 patients. Analysis of the accuracy of drug use by looking at medical record data and JNC 8 guidelines and calculating the percentage of accuracy. Based on the results of the research conducted to obtain the advantage of using antihypertensive drugs in hypertensive patients at the Boyolali 1 Public Health Center for the January-June 2022 period based on the right criteria the drug obtained an accuracy of 76.47% and based on the correct dose obtained a percentage of 99.02%, the results can be purchased evaluation of the accuracy of using antihypertensive drugs at the Boyolali 1 Health Center for the January-June 2022 period shows that the level of accuracy of therapy has not reached 100%. ABSTRAK Hipertensi lebih dikenal sebagai penyakit kardiovaskular atau jantung. Hipertensi masih menjadi salah satu penyakit yang tingkat prevalensinya mengalami peningkatan. Masalah yang sering ditemukan pada penatalaksanaan penyakit hipertensi adalah ketidaktepatan penggunaan obat dan dosis antihipertensi. Penelitian ini dilakukan untuk mengetahui presentase ketepatan penggunaan obat antihipertensi yang meliputi tepat obat dan tepat dosis di Puskesmas Boyolali 1 periode Januari – Juni 2022.Penelitian ini merupakan penelitian yang menggunakan rancangan penelitian deskriptif secara retrospektif dengan melihat data rekam medik pasien hipertensi. Sampel dalam penelitian ini adalah pasien dengan diagnosa hipertensi pada periode Januari-Juni 2022 di Puskesmas Boyolali 1 yang sesuai dengan kriteria inklusi dan eksklusi sejumlah 102 pasien. Analisis ketepatan penggunaan obat dengan melihat data rekam medik dan guideline JNC 8 dan dihitung presentase ketepatannya. Berdasarkan hasil penelitian yang dilakukan diperoleh ketepatan penggunaan obat antihipertensi pada pasien hipertensi di Puskesmas Boyolali 1 Periode Januari-Juni 2022 berdasarkan kriteria  tepat obat diperoleh presentase ketepatan sebesar 76,47% dan berdasarkan kriteria tepat dosis diperoleh presentase sebesar 99,02%, maka dapat disimpulkan bahwa hasil evaluasi ketepatan penggunaan obat antihipertensi di Puskesmas Boyolali 1 Periode Januari-Juni 2022 menunjukan hasil ketepatan terapi yang belum mencapai 100%.
Penetapan Kadar Flavonoid Ekstrak Etanol Daun Gatal (Laportea decumana (Roxb.) Wedd) Dengan Menggunakan Metode Spektrofotometri UV-Vis: Determination of Flavonoid Level of Ethanol Extract of Laportea decumana (Roxb.) Wedd Using UV-Vis Spectrophotometry Method Mewar, Djulfikri; Sitti Hadijah; Nadila Bandian
Indonesian Journal of Pharmacy and Natural Product Vol. 6 No. 02 (2023): Indonesian Journal of Pharmacy and Natural Product
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ijpnp.v6i02.2400

Abstract

Laportea decumana (Roxb.) Wedd is a shrub from the uritaceae family which when applied to the whole body will cause a very itchy effect. Empirically, Maluku people use L.decumana leaves as a traditional medicine for soreness, anti-pain and headache. The purpose of this study was to determine the levels of flavonoid compounds contained in ethanol extract of L. decumana. Extraction of L decumana was done by maceration method using 70% ethanol. The extract yield was 4.92%. Determination of total flavonoid compounds was carried out based on the AlCl3 method with total flavonoids expressed in QE (Quersetin Equivalent using a UV-Vis spectrophotometer at a wavelength of 414 nm. The results showed that the average value of total flavonoid content was 3.189 mgQE/gr extract. ABSTRAK Daun gatal (Laportea decumana (Roxb.) Wedd) adalah sejenis tanaman perdu yang berasal dari family uritaceae dimana jika dioleskan ke seleruh tubuh akan menimbulkan efek yang sangat gatal. Secara empiris masyarakat maluku menggunakan daun gatal sebagai obat tradisional untuk pegal, anti nyeri dan sakit kepala. Tujuan dari penelitian ini adalah untuk menenetukan kadar senyawa flavonoid yang terdapat dalam ekstrak etanol  L decumana. Ekstraksi L decumana dilakukan dengan metode maserasi menggunakan etanol 70%. Hasil rendamen ekstrak sebanyak 4,92%. Penentuan senyawa flavonoid total dilakukan berdasarkan metode AlCl3 dengan total flavonoid yang dinyatakan dalam QE (Quersetin Ekuivalen dengan menggunakan spektrofotometer UV-Vis pada panjang gelombang 414 nm. Hasil penelitian  menunjukan bahwa nilai rata-rata kandungan flavonoid total adalah 3,189 mgQE/gr ekstrak

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