International Journal of Health, Engineering and Technology
International Journal of Health, Engineering and Technology (IJHET) is to provide research media and an important reference for the progress and dissemination of research results that support high-level research in the field of Health, Engineering and technology. Original theoretical work and application-based studies, which contribute to a better understanding of all areas of Health, Engineering and Technology , the journal publishes articles six times a year in May, July, September, November, January and March. Scope: International Journal of Health, Engineering and Technology (IJHET) is to provide a research medium and an important reference for the advancement and dissemination of research results that support high-level research in the fields of Health, Engineering and Technology Research. Original theoretical work and application-based studies, which contributes to a better understanding all fields of Health, Engineering and Technology Research. Healt : Clinical Nutrition, Community Nutrition, Institutional Nutrition, Food Technology, Food Security, Pediatric Physiotherapy, Geriatric Physiotherapy, Cardiovascular and Pulmonary Physiotherapy, Musculoskeletal Physiotherapy, Sports Physiotherapy, Public Health, Community Sanitation, Environmental Health, Nursing, Biology, Medicine, Pharmacy. Engineering : The field of mechanical Engineering include expertise in energy conversion, construction machinery, manufacturing and materials. The field of Electrical Engineering which includes skills power engineering, telecommunications engineering and information, as well as control and instrumentation. The field of Chemical Engineering which includes expertise in the field of new and renewable energy, the environment field. The field of Civil Engineering which includes expertise in the fields of structural, geotechnical, transportation and water. The field of Metallurgical Engineering which includes expertise in extraction, manufacturing and characterization of materials. The field of Industrial Engineering which includes enterprise management system, working system and the ergonomics and manufacturing systems. Technology: Open Source Application, Information Management, Information System, IT & Social Impact, Geographical Information System, Web Engineering, Database Design & Technology, Data Warehouse, Network Security, Data Mining, Computer Architecture Design, Mobile Programming.
Articles
438 Documents
<![CDATA[Posterior Ischaemic Optic Neuropathy (Pion) Secondary To Distal Segment Stenosis Of The Left Ophthalmic Artery: A Rare Case Report ]]>
<![CDATA[Iswara, Delta]]>;
<![CDATA[Asyrofi, Hasna Okta]]>;
<![CDATA[Hernawan Hernawan]]>
<![CDATA[ International Journal of Health Engineering and Technology Vol. 5 No. 1 (2026): IJHET MAY 2026 ]]>
Publisher : <![CDATA[CV. AFDIFAL MAJU BERKAH ]]>
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DOI: 10.55227/ijhet.v5i1.733
<![CDATA[Ischaemic optic neuropathy (ION) is a vision-threatening condition caused by impaired arterial blood supply to the optic nerve. Posterior ischaemic optic neuropathy (PION) is a rare subtype that often presents without funduscopic abnormalities in the acute phase, making diagnosis challenging. We report a case of a 50-year-old man who presented with sudden, painless monocular visual loss in the left eye, accompanied by hemisensory deficits. Ophthalmic examination revealed no optic disc abnormalities, while automated perimetry demonstrated an inferior arcuate visual field defect. Brain magnetic resonance imaging showed a right corona radiata infarction, and digital subtraction angiography confirmed stenosis of the distal branches of the left ophthalmic artery. These findings supported the diagnosis of PION secondary to ophthalmic artery stenosis, an uncommon etiology of ION. The patient had uncontrolled hypertension as a major vascular risk factor and was treated with antiplatelet therapy, resulting in clinical improvement of visual acuity. This case highlights the importance of comprehensive vascular evaluation in patients with suspected PION and emphasizes ophthalmic artery stenosis as a rare but significant cause of ischaemic optic neuropathy. Early recognition of the underlying vascular pathology may facilitate appropriate management and help prevent further ischemic complications.]]>
<![CDATA[Near-Fatal Asthma With Severe Hypercapnic Respiratory Failure Requiring Mechanical Ventilation In A Resource-Limited Setting: A Case Report ]]>
<![CDATA[Triagustina, Sinta]]>;
<![CDATA[Iswara, Delta]]>;
<![CDATA[Karera, Anggita Dian]]>;
<![CDATA[Hasyim, Rois]]>;
<![CDATA[Saksana, Rachmad Aji]]>
<![CDATA[ International Journal of Health Engineering and Technology Vol. 5 No. 1 (2026): IJHET MAY 2026 ]]>
Publisher : <![CDATA[CV. AFDIFAL MAJU BERKAH ]]>
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DOI: 10.55227/ijhet.v5i1.734
<![CDATA[Near-fatal asthma (NFA) is a life-threatening manifestation of acute severe asthma characterized by hypercapnia, respiratory acidosis, altered consciousness, and the need for invasive mechanical ventilation. Early recognition and timely airway stabilization are essential to prevent respiratory arrest and mortality, particularly in resource-limited settings. A 41-year-old woman with a history of asthma was brought to the emergency department with decreased consciousness and severe respiratory distress. On arrival, her Glasgow Coma Scale score was 5, respiratory rate was 35 breaths per minute, and oxygen saturation was 46% on room air. Arterial blood gas analysis demonstrated life-threatening hypercapnic respiratory failure (pH 6.954; PaCO₂ 95.4 mmHg; P/F ratio 87). Due to worsening respiratory failure and decreased level of consciousness, the patient underwent immediate endotracheal intubation and invasive mechanical ventilation and was admitted to the intensive care unit. She received systemic corticosteroids, repeated bronchodilator therapy, aminophylline infusion, and broad-spectrum antibiotics. Lung-protective ventilatory strategies with prolonged expiratory time were applied. The patient improved rapidly and was successfully extubated on the second day of mechanical ventilation, with subsequent discharge in stable condition. Appropriate ventilatory strategies combined with guideline-based pharmacological therapy are essential to improve outcomes in patients with near-fatal asthma presenting with severe hypercapnic respiratory failure, even in resource-limited settings.]]>
<![CDATA[Changes In The Level Of Knowledge And Attitudes Of Adolescent Girls After Providing Health Education About Fluor Albus At Gunungjati Twin Middle School ]]>
<![CDATA[Nanda Rida Wihasti]]>
<![CDATA[ International Journal of Health Engineering and Technology Vol. 5 No. 1 (2026): IJHET MAY 2026 ]]>
Publisher : <![CDATA[CV. AFDIFAL MAJU BERKAH ]]>
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DOI: 10.55227/ijhet.v5i1.830
<![CDATA[Vaginal discharge (fluor albus) is a reproductive health problem frequently experienced by adolescent girls and is often considered a normal condition, thus receiving little attention. Lack of appropriate knowledge and attitudes can influence reproductive hygiene behavior and increase the risk of pathological fluor albus. This study aims to determine changes in the level of knowledge and attitudes of adolescent girls after health education about fluor albus was provided at Gunungjati Kembaran Junior High School. The study used a quantitative approach with a pre-test design.‑One Group Pretest–Posttest experimental study. The population was all female adolescents at Gunungjati Kembaran Junior High School with a total sample of 29 respondents. Data collection was conducted using a knowledge and attitude questionnaire, then analyzed descriptively using univariate analysis, paired sample t-test, and Wilcoxon Signed Rank Test. The results showed an increase in the average knowledge score from 56.62 before the intervention to 74.62 after the intervention (p = 0.000). All respondents had a positive attitude after the intervention with no remaining negative attitudes. In conclusion, health education about fluor albus had a significant effect in improving the knowledge and attitudes of female adolescents in maintaining reproductive organ hygiene, thus proving this intervention effective.]]>
<![CDATA[Formulation And Evaluation Of Instant Drink Powder Preparation With A Combination Of Vitamin C And Zinc Sulfate Monohydrate ]]>
<![CDATA[Faneshia Nabil Ayushita]]>;
<![CDATA[Halyza Nada Kirana]]>;
<![CDATA[Embun Larasati Kuncoro]]>;
<![CDATA[Fauzi Rizki Fadhilah]]>;
<![CDATA[Zefanya Yoga Permana Purba]]>
<![CDATA[ International Journal of Health Engineering and Technology Vol. 5 No. 1 (2026): IJHET MAY 2026 ]]>
Publisher : <![CDATA[CV. AFDIFAL MAJU BERKAH ]]>
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DOI: 10.55227/ijhet.v5i1.833
<![CDATA[Vitamin C and Zinc Sulfate Monohydrate is a combination of active substances that play a role in improving the immune system and maintaining body health. This research aims to create a powder formulation of a combination of vitamin C and zinc sulfate that is safe for consumption. Vitamin C is a very sensitive substance and can be degraded into dehydroascorbic acid due to photooxidation and hydrolysis reactions. Vitamin C is easily degraded in aqueous media, at high pH, high temperatures, in the presence of oxygen and metal ions. Formulation in solid form such as powder is often chosen to increase the chemical stability and shelf life of vitamin C. Formulation of vitamin C and zinc in powder form also provides convenience for consumers who have difficulty swallowing in pill, tablet, or capsule form. The evaluation results showed that the preparation had good characteristics in most parameters, including white color, smooth texture, odorless, slightly sweet and sour taste, particle size of 0.7795 mm, flow time of 10 seconds, water content of 2.73%, angle of repose of 31.52°, dissolution time of 1 minute 29 seconds, bulk density of 0.64, tap density of 0.72, Hausner ratio of 1.12, and compressibility index of 11.11%. However, the preparation did not meet the requirements for particle size distribution due to the excessive number of fines and a pH value of 3.57 which was below the specified range (4–7). Therefore, the resulting formulation still requires further optimization to improve compliance with the preparation quality standards.]]>
<![CDATA[Overview of Insulin Leaf Tea Administration on Blood Sugar People in Kemutug Kidul Village ]]>
<![CDATA[Putri, Rizka Intan Amelia]]>;
<![CDATA[Endiyono Endiyono]]>;
<![CDATA[Meida Laely Ramdani]]>
<![CDATA[ International Journal of Health Engineering and Technology Vol. 5 No. 1 (2026): IJHET MAY 2026 ]]>
Publisher : <![CDATA[CV. AFDIFAL MAJU BERKAH ]]>
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DOI: 10.55227/ijhet.v5i1.837
<![CDATA[This study was initiated by the high incidence of hyperglycemia and the need for simple, safe, and easily implemented complementary therapies in the community. The aim of this study was to analyze the effectiveness of insulin leaf tea on blood glucose levels in the community in Kemutug Kidul Village. This study used a quasi-experimental design with a one-group pretest-posttest model. The population consisted of 36 diabetes mellitus sufferers, while the sample was selected using purposive sampling of 5 respondents. The research instruments included a glucometer, observation sheets, and intervention guidelines, while the data were analyzed descriptively by comparing pre- and post-intervention values. The results showed that all respondents experienced a decrease in blood glucose levels after consuming insulin leaf tea for 10 days, with an average decrease of 131.2 mg/dl. It was concluded that insulin leaf tea has the potential to be a non-pharmacological complementary therapy in helping control blood glucose, although this finding is still limited by the small sample size and the lack of a control group.]]>
<![CDATA[Systematic Literature Review: The Effect Of Different Binders On Paracetamol Tablets ]]>
<![CDATA[Nadine Ayu Syaima Gustaf Prins]]>;
<![CDATA[Iqlima Farah Novantri]]>;
<![CDATA[Jessica Putri Sinaga]]>;
<![CDATA[Clarissa Zuha Swari]]>
<![CDATA[ International Journal of Health Engineering and Technology Vol. 5 No. 1 (2026): IJHET MAY 2026 ]]>
Publisher : <![CDATA[CV. AFDIFAL MAJU BERKAH ]]>
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DOI: 10.55227/ijhet.v5i1.840
<![CDATA[This study aims to examine the effect of different binders on the physical quality of paracetamol tablets using the Systematic Literature Review (SLR) method. Paracetamol tablets are one of the preparations widely used as analgesics and antipyretics, so the choice of binder plays an important role in determining tablet quality, such as hardness, friability, disintegration time, dissolution, and physical and chemical stability. The method used is a literature study of various studies related to variations in binders in paracetamol tablet formulations and evaluation of their physical quality. The results of the study indicate that the type and concentration of binders have a significant effect on tablet characteristics. Binders such as PVP, gelatin, kawista pectin, konjac glucomannan, durian seed starch, cassava starch, pregelatinized corn starch phosphate, and various other natural starches show different effects on tablet hardness, friability, disintegration time, and dissolution. Natural binders such as pectin and modified starch show the most optimal results because they are able to produce tablets with good physical quality while maintaining optimal drug release. While synthetic binders such as PVP and gelatin provide strong binding strength and improve tablet stability, their use in high concentrations can prolong disintegration time and decrease dissolution. Overall, selecting the right binder is crucial for producing paracetamol tablets that meet pharmacopoeial requirements and provide optimal therapeutic efficacy.]]>
<![CDATA[Description Of Hemodynamic Status Of Conscious Extubation Of Patients With Tonsillectomy Procedures Using General Anesthesia ]]>
<![CDATA[Rohyaji, Cili]]>;
<![CDATA[Tati Hardiyani]]>
<![CDATA[ International Journal of Health Engineering and Technology Vol. 5 No. 1 (2026): IJHET MAY 2026 ]]>
Publisher : <![CDATA[CV. AFDIFAL MAJU BERKAH ]]>
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DOI: 10.55227/ijhet.v5i1.841
<![CDATA[Post-tonsillectomy awake extubation under general anesthesia has the potential to trigger hemodynamic fluctuations due to sympathetic stimulation, but prospective data in the Indonesian context is still limited. This study aims to describe the hemodynamic status in the post awake extubation period in tonsillectomy patients. Using a descriptive quantitative design, the population included 29 patients aged 12–35 years at Wijayakusuma Hospital III Purwokerto (December 2025–January 2026) with total sampling. Primary data were measured via bedside monitors and observation sheets, and univariate analysis was performed using SPSS. The results showed that the majority of respondents were 17–25 years old (51.7%) and female (65.5%). In the post-awake extubation period, hemodynamic findings demonstrated pre-hypertensive systolic and diastolic blood pressure (44.8% and 55.2%, ), while mean arterial pressure (79.3%), pulse rate (62.1%), respiratory rate (75.9%), and oxygen saturation (100%) remained within normal limits.]]>
<![CDATA[Literature Review Of Drug-Receptor Interactions Based On Molecular Docking From The Perspective Of Lock And Key Theory ]]>
<![CDATA[Saeful Amin, Saeful Amin]]>;
<![CDATA[Nazmie Nurtsalis]]>;
<![CDATA[Dina Sumida Rosydiana]]>;
<![CDATA[Andra Nadya Hidayat]]>
<![CDATA[ International Journal of Health Engineering and Technology Vol. 5 No. 1 (2026): IJHET MAY 2026 ]]>
Publisher : <![CDATA[CV. AFDIFAL MAJU BERKAH ]]>
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DOI: 10.55227/ijhet.v5i1.842
<![CDATA[Drug-receptor interactions are the primary basis for determining the effectiveness of a therapy. Understanding the mechanisms of these interactions continues to evolve with advances in computational technology, one of which is through the molecular docking approach. This method enables in silico analysis of ligand-receptor interactions, including predictions of binding affinity, complex stability, and the types of molecular interactions that occur. Furthermore, the lock and key theory is a fundamental concept in explaining the structural compatibility between drugs and receptors, which influences bond strength and specificity. The method used in this review is a literature review from various scientific databases such as PubMed, Google Scholar, and ScienceDirect, with journals published in 2020 or later as inclusion criteria. The results show that oseltamivir has high affinity for neuraminidase through specific interactions such as hydrogen bonding and electrostatic binding. However, mutations in the receptor can lead to drug resistance. Therefore, understanding the mechanisms of molecular interactions is crucial for the development of more effective antiviral drugs.]]>
<![CDATA[The Impact Of Stunting Prevention Counseling Through Education On The Importance Of The First 1,000 Days Of Life ]]>
<![CDATA[Riza Savita, Riza Savita]]>;
<![CDATA[Nadya Nuraini Putri]]>;
<![CDATA[Dea Amanda Budi Lestari]]>;
<![CDATA[Natasya Ayu]]>
<![CDATA[ International Journal of Health Engineering and Technology Vol. 5 No. 1 (2026): IJHET MAY 2026 ]]>
Publisher : <![CDATA[CV. AFDIFAL MAJU BERKAH ]]>
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DOI: 10.55227/ijhet.v5i1.843
<![CDATA[Stunting remains a public health issue in Indonesia, including Tanjung Gunung Village, Central Bangka Regency. Limited maternal knowledge of nutrition during the first 1,000 days of life (1,000 HPK), suboptimal breastfeeding practices, and cultural food taboos contribute to stunting risk. This community service aims to improve nutritional knowledge among high-risk pregnant women (4T) as a stunting prevention effort. A descriptive design with a participatory educational approach was applied through interactive counseling and discussion. The activity involved 25 high-risk pregnant women using leaflets and audiovisual media. Evaluation was conducted descriptively through observation of participation and responses. The results showed good acceptance of the material and high participant engagement. Community-based 1,000 HPK nutrition education is feasible as a promotive and preventive strategy for stunting prevention.]]>
<![CDATA[Review Of Natural Compounds And Medicinal Chemistry Approaches In Drug Development ]]>
<![CDATA[Amin, Saeful]]>;
<![CDATA[Hilna Putri Herlina]]>;
<![CDATA[Wulandari Wulandari]]>;
<![CDATA[Miela Agustin]]>
<![CDATA[ International Journal of Health Engineering and Technology Vol. 5 No. 1 (2026): IJHET MAY 2026 ]]>
Publisher : <![CDATA[CV. AFDIFAL MAJU BERKAH ]]>
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DOI: 10.55227/ijhet.v5i1.844
<![CDATA[The increasing prevalence of degenerative and infectious diseases has encouraged the development of more effective, selective, and safer therapeutic agents. Natural compounds and medicinal chemistry approaches have demonstrated considerable potential in modern drug discovery due to their diverse pharmacological activities and structural complexity. This study aims to review the role of bioactive natural compounds and computational approaches in contemporary drug development. The method employed was a literature review based on recent scientific publications discussing medicinal chemistry, molecular docking, quantitative structure–activity relationship analysis, artificial intelligence-assisted drug design, and nanoformulation strategies. The findings indicate that several natural compounds, particularly flavonoids and quercetin, exhibit promising anticancer, antidiabetic, antioxidant, and antibacterial activities through interactions with various biological targets. Computational approaches such as molecular docking, virtual screening, predictive modeling, and deep QSAR were shown to improve the efficiency of lead identification and molecular optimization. Furthermore, nanoformulation systems contribute to enhancing bioavailability, molecular stability, and therapeutic effectiveness of bioactive compounds. Despite these advantages, challenges including compound complexity, ADMET limitations, and the necessity for experimental validation remain important considerations in drug development. In conclusion, the integration of natural compounds, medicinal chemistry, and computational technologies provides significant opportunities for accelerating and optimizing modern drug discovery and development.]]>
