cover
Contact Name
Rico Nur Ilham
Contact Email
radjapublika@gmail.com
Phone
+6281238426727
Journal Mail Official
radjapublika@gmail.com
Editorial Address
Jl. Cempaka Putih, Sp. Tiga Blang Rayeuk, Dsn. Angsana, Kelurahan Hagu Barat Laut, Kec. Banda Sakti, Lhokseumawe, Provinsi Aceh, 24315
Location
Kota lhokseumawe,
Aceh
INDONESIA
MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation
ISSN : -     EISSN : 29867754     DOI : https://doi.org/10.59733/medalion
Core Subject : Health,
MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation | ISSN (e): 2986-7754 is a peer-reviewed, open access journal which publishes original research articles and review articles in all areas of nursing and midwifery, research and education. The aim of the journal is to contribute to the growing field of nursing practice and provide a platform for researchers, physicians and healthcare professionals. Topics of interest include: Nursing education Community nursing Specialist nursing topics Policies in nursing and healthcare Ethical issues Healthcare systems Healthcare management Pediatrics nursing
Articles 205 Documents
BREAKTHROUGH IMMUNOMODULATION THERAPY IN IDIOPATHIC PULMONARY FIBROSIS: A NARRATIVE LITERATURE REVIEW Amiruddin; Faridj Maulana Amir
MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation Vol. 6 No. 4 (2025): December
Publisher : PT. Radja Intercontinental Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59733/medalion.v6i4.250

Abstract

Background: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with a poor prognosis. Several antifibrotics such as pirfenidone and nintedanib have been shown to slow the decline in lung function but cannot stop the ongoing or existing fibrosis process. Recent evidence suggests that immune dysregulation, including macrophage activation and PD-L1 expression on fibroblasts, plays a key role in the pathogenesis of IPF, thus encouraging the emergence of potential immunomodulation therapies. Methods: This paper attempts to review several English-language literature from 2015–2025 through PubMed, Scopus, and ClinicalTrials.gov. Articles relevant to immunotherapy, immunomodulators, or immune mechanisms in IPF were included, while non-scientific or non-immune-related publications were ignored. Results: A total of 15 primary publications were identified. Immunotherapy approaches such as PD-L1 inhibition, Treg activation, and IL-4/IL-13 blockade have shown antifibrotic and immunoregulatory effects. New agents such as the TNIK inhibitor (ISM001-055), the peptide LTI-03, and CAR-Treg therapy have shown promising early results in translational models and early-phase clinical trials. Conclusion: Immunotherapy has the potential to be a novel approach to IPF management by targeting the immune microenvironment. Further trials are needed to ensure safety and efficacy for long-term treatment.
FACTORS RELATED TO OCCUPATIONAL SAFETY AND HEALTH SYSTEMS AMONG COAL HANDLING WORKERS AT MEULABOH SEAPORT Dedek Kasmiyanda; Marniati; T. Alamsyah; Firman Firdaus Saputra; Zakiyuddin
MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation Vol. 6 No. 4 (2025): December
Publisher : PT. Radja Intercontinental Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59733/medalion.v6i4.254

Abstract

Coal loading and unloading workers at Meulaboh Seaport are at high risk of accidents and health problems due to dust exposure, heavy workloads, and unsafe working conditions. Although the Occupational Safety and Health (OSH) management program has been implemented, its execution remains low. Many workers are not disciplined in using Personal Protective Equipment (PPE), OSH training is not optimal, and supervision is still weak. This study aims to analyze the factors associated with the implementation of OSH management programs among loading and unloading workers at Meulaboh Seaport. The study used a quantitative method with a cross-sectional design and involved 32 respondents. Data analysis was conducted using univariate and bivariate techniques. The results showed a significant relationship between work discipline (p = 0.005), training (p = 0.010), supervision (p = 0.022), and OSH evaluation (p = 0.010) with the implementation of the OSH management program. It is recommended that the management of Meulaboh Seaport, as the company’s policy maker, continuously improve the existing OSH management system to ultimately enhance worker performance, which will bring both financial and non-financial benefits to the seaport. For workers, it is advised to prioritize occupational safety and health by complying with the established OSH management system.
THE RELATIONSHIP BETWEEN FAMILY HYGIENE PRACTICES AMONG FISHING HOUSEHOLDS AND STUNTING AMONG UNDER-FIVE CHILDREN IN PADANG SEURAHET VILLAGE Rupiana; Teungku Nih Farisni; Fakhrurradhi Luthfi; T. Alamsyah; Yulizar
MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation Vol. 6 No. 4 (2025): December
Publisher : PT. Radja Intercontinental Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59733/medalion.v6i4.255

Abstract

Stunting remains a major public health problem in Indonesia, particularly in coastal areas where family sanitation and hygiene conditions are inadequate. Padang Seuraheut Village, Johan Pahlawan Subdistrict, West Aceh, is a coastal area predominantly inhabited by fishing families with limited environmental sanitation, restricted access to clean water, and suboptimal hygiene practices. This study aimed to analyze the relationship between family hygiene practices and the incidence of stunting among under-five children in the village. This study employed a quantitative approach with a cross-sectional design and was conducted from August to December 2025. The study population comprised all children aged 12–59 months totaling 1,442, with a sample of 94 children selected using simple random sampling. Data on family hygiene practices were collected through mothers as respondents using questionnaires and observation checklists. Data were analyzed using the Chi-Square test. The results showed that all hygiene and sanitation variables were significantly associated with the incidence of stunting (p < 0.05). Poor handwashing practices with soap were strongly associated with stunting (100%), as were inadequate latrine conditions (75.0%), unhygienic food storage and preparation (76.6%), and improper waste and wastewater disposal (73.1%). These findings indicate that family hygiene practices and environmental sanitation play a substantial role in increasing the risk of stunting among under-five children. Improvements in sanitation facilities, family hygiene education, and community-based interventions in coastal areas should be prioritized as strategic measures for stunting prevention.
DETERMINANTS OF HOME ENVIRONMENTAL HEALTH RELATED TO PULMONARY TUBERCULOSIS SCORE IN THE WORKING AREA OF UPTD JOHAN PAHLAWAN PUBLIC HEALTH CENTER Cut Fidha Balkis; Mardi Fadillah; Ernawati; T.M Rafsanjani
MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation Vol. 6 No. 4 (2025): December
Publisher : PT. Radja Intercontinental Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59733/medalion.v6i4.256

Abstract

This study aims to analyze the relationship between determinants of home environmental health, including ventilation, lighting, residential density, temperature and humidity, and home sanitation with the incidence of Pulmonary Tuberculosis in the working area of the Johan Pahlawan Community Health Center (UPTD). The research method uses a quantitative approach with a correlational design. The study population is households that have family members with pulmonary TB based on the Puskesmas medical records, with a sample of 50 respondents determined using a purposive sampling technique . Data were collected through questionnaires and home observations, then analyzed using descriptive statistical tests, validity and reliability tests, classical assumption tests, and multiple linear regression analysis with the help of SPSS software version 26. The results of the study indicate that residential density has a positive and significant effect on the incidence of pulmonary TB, while home sanitation has a negative and significant effect on the incidence of pulmonary TB. Meanwhile, ventilation, lighting, and temperature and humidity do not show a statistically significant relationship with the incidence of pulmonary TB. The conclusion of this study confirms that residential density and home sanitation are the main determinants of the incidence of pulmonary TB, so that prevention efforts based on improving the home environment are needed to reduce the risk of pulmonary TB transmission in the community.
THE EFFECTIVENESS OF COMMUNICATION, INFORMATION, AND EDUCATION ON PARENTAL KNOWLEDGE OF PEDIATRIC RESPIRATORY INFECTION PATIENTS AT JOHAN PAHLAWAN HEALTH CENTER Ayu Mardhana Lisa
MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation Vol. 6 No. 4 (2025): December
Publisher : PT. Radja Intercontinental Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59733/medalion.v6i4.257

Abstract

Acute Upper Respiratory Infections (ARI) are among the leading infectious diseases contributing significantly to global morbidity and mortality, particularly among children under five years of age. Each year, an estimated four million deaths of children under five are attributed to ARI. Successful management of ARI can be improved when caregivers possess adequate knowledge about the disease and the correct use of medications. One approach to strengthening the role of caregivers is through the provision of Communication, Information, and Education (CIE). This study aimed to evaluate the effectiveness of CIE in improving the knowledge of caregivers of pediatric ARI patients at the Johan Pahlawan Community Health Center, West Aceh Regency. This study employed a quantitative approach with a pre-experimental design. The total sample consisted of 33 respondents, including parents or caregivers of pediatric ARI patients who visited the Johan Pahlawan Community Health Center. Data analysis was conducted using univariate analysis to describe the distribution of respondents’ knowledge levels and bivariate analysis using the Paired Sample t-test to assess the effectiveness of the CIE intervention. The results showed a p-value of 0.000 (p < 0.05), indicating a significant difference in knowledge levels before and after the CIE intervention. Therefore, it can be concluded that the provision of CIE is significantly effective in improving the knowledge of caregivers of pediatric ARI patients at the Johan Pahlawan Community Health Center, West Aceh Regency. Consequently, CIE should be implemented regularly and continuously as part of health promotion efforts to prevent and reduce the incidence of ARI among children.