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Giftania Wardani Sudjarwo
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INDONESIA
Journal of Pharmacy Science and Technology
Published by Universitas Hang Tuah
ISSN : -     EISSN : 26140993     DOI : https://doi.org/10.30649/pst
Core Subject : Health,
Medicine & Pharmacology
The Journal of Pharmaceutical Science and Technology is a journal for scientific publications on all pharmaceutical aspects including pharmaceutical science (pharmaceutical technology, pharmaceutical chemistry, pharmaceutical biology, pharmacognosy, microbiology and pharmaceutical biotechnology), community pharmacy, clinical pharmacy until explore the potential of marine biota. This journal is published twice a year to provide a means for pharmacists and other health professionals to share research results to improve the science of pharmaceuticals. The Journal of Pharmaceutical Science and Technology is intended to present the best quality research articles in pharmaceutical science, community pharmacy and clinical pharmacy to become scientific guides in fields related to science and pharmaceutical technology. This journal is a peer-reviewed journal and publishes original research articles on all aspects of science and pharmaceutical technology. This journal accepts original articles as well as for other categories such as review articles and case reports for all aspects of pharmaceutical science, pharmacy clinics and community pharmacy.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 48 Documents
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KAJIAN EFEK SAMPING ANTIDEPRESAN TERHADAP FUNGSI SEKSUAL Vita Manda; Amitasari Damayanti
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 3 No. 2: Desember 2022
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v3i2.49

Abstract

Depression is a mental health disorder that is a severe mood disorder characterized by the appearance of symptoms of a decrease in mood (mood), such as loss of interest, energy, concentration, and disturbances in appetite and sleep. One of the treatments for depression is the use of antidepressants. Still, sexual dysfunction has been reported as a side effect of using antidepressants, especially Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs), and other antidepressants, namely Tricyclic Antidepressants (TCAs) have also been reported. ). Research results on the side effects of using antidepressant drugs have been reported to have decreased sexual arousal and impaired orgasm (orgasm development). There are side effects that occur in the use of SSRI, SNRI, and TCA antidepressants on sexual function
REVIEW ARTIKEL STUDI FITOKIMIA DAN FARMAKOLOGI TEMU PUTIH (Curcuma zedoaria) Yuyun Rahmawati; Arista Wahyu Ningsih; Irvan Charles; Retha Amalia Rahma Dewi; Fina Agustin; Salsabilla Rohadatul A; Ervina Aryani
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Juli 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i1.54

Abstract

Indonesia, which is rich in biodiversity, is very much in harmony with the culture or habits of the people who still uphold hereditary values, especially in terms of herbal (traditional) medicine. Utilization of medicinal plants in Indonesia has begun to develop rapidly, where medicinal plants used can be used directly or through an extraction process to obtain compounds that have pharmacological and therapeutic effects. One of the medicinal plants that is often used by the Indonesian people is a type of rhizome that includes ginger, yellow turmeric, white ginger, ginger, and many more. One of the rhizomes that are efficacious for health is white ginger (Curcuma zedoaria). In the test white ginger extract (Curcuma zedoaria) was positive for the presence of flavonoids, alkaloids, tannins and saponins, curcumin. These compounds that make Temu Putih (Curcuma zedoaria) have pharmacological activities including antioxidant, anti-inflammatory, anticancer, antibacterial, as an immunodulator, anti-angiogenic and can act as an antitumor.
EKSTRAKSI TANAMAN OBAT KELUARGA TEMU HITAM (Curcuma aeruginosa Roxb.) SEBAGAI UPAYA PENAMBAH NAFSU MAKAN ANAK Yauwan Tobing Lukiyono; Ersalina Nidianti; Salfa Salsabilah Zain
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Juli 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i1.55

Abstract

Indonesia is one of the countries in the world that has very diverse and very large amounts of wealth, such as  plants. As for the wealth of plants in question, such as the existence of plants that have properties for body health and growth and development. Many mothers and caregivers complain about decreased appetite because if energy and nutritional needs are not met there will be a slowdown in physical growth, mental development and mental retardation. One of the plants that can be used to increase appetite is black temu (Curcuma aeruginosa Roxb). Black rhizome belongs to the Zingiberaceae family, contains black compounds including essential oils, tanim, curikumol, kurkumenol, isokurkumelon, kurzerenon, kurdion, kurkumolactone, germakron and curcumin. The purpose of this research is to find out further benefits and prove whether the content of black rhizome can increase appetite in children. This study uses the literature method by seeking various sources from previous studies. The results obtained show that the content of essential oils has the potential to reduce fat so that it can trigger appetite, while the content of curcuminoids can cause relaxation of the intestine in the gastrointestinal tract which can help digestion of food and absorption of food ingredients by increasing the work of the stomach so that the stomach feels empty. The conclusion obtained is that these two ingredients can increase appetite in children so that they can get their appetite back and the energy and nutritional needs of their ody will be fulfilled perfectly.
PENGARUH AROMATERAPI JAHE (Zingiber officinale) TERHADAP MUAL MUNTAH PASIEN KANKER PASCA KEMOTERAPI yauwan Tobing Lukiyono tobing; Ersalina Nidianti; Salfa Salsabilah Zain
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Juli 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i1.56

Abstract

Chemotherapy is a medical procedure used to stop the growth of cancer cells. Chemotherapy involves injecting or ingesting chemicals. Cytotoxic chemotherapy cause unpleasant side effects like nausea and vomiting. Non-pharmacological therapies, such as combination therapy with ginger aromatherapy and progressive muscle relaxation, can be used to treat nausea and vomiting. By lowering or stopping nausea and vomiting, ginger aromatherapy can be comforting. This study used the literature method by analyzing various sources from previous  research which are then used as reference material for making this article. The results obtained were that the ginger aromatherapy inhibits serotonin receptors, which prevents serotonin released and contractions of the stomach muscles, hence reducing nausea and vomiting. The conclusion obtained is that ginger aromatherapy has been proven to have a calming effect and make a person relax. The compounds present in ginger such as zingiber and zingiberol have anti-emetic effects which can prevent nausea and vomiting.
SKRINING FITOKIMIA DAN ANALISIS KADAR FLAVONOID TOTAL FRAKSI ETIL ASETAT KULIT BUAH DURIAN MERAH (Durio graveolens Becc.) Dengan METODE SPEKTROFOTOMETRI Uv-VIS : SKRINING FITOKIMIA DAN ANALISIS KADAR FLAVONOID TOTAL FRAKSI ETIL ASETAT KULIT BUAH DURIAN MERAH (Durio graveolens Becc.) Dengan METODE SPEKTROFOTOMETRI Uv-VIS Tri Esti Kusuma Bakti; Mahfur Mahfur
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Juli 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i1.57

Abstract

Flavonoids are natural compounds found in durian. One of the most important components known as natural compounds, which have the potential as anti-inflammatory and antioxidant. The secondary metabolites of flavonoids in the skin of plants can be affected by the process of photosynthesis. The purpose of this study was to measure the total flavonoid content and ethyl acetate fraction of red durian skin using the Uv-Vis spectrophotometry method. This research uses a type of descriptive research method. Extraction of red durian fruit skin (Durio graveolens Becc) using maceration method with 70% ethanol solvent. Fractionation was carried out using the liquid-liquid fractionation method using ethyl acetate. Thin Layer Chromatography (TLC) was used to identify flavonoids with the stationary phase of silica gel GF254 and the mobile phase of methanol:ethyl acetate 7:3 for flavonoid compounds. Quantitative analysis was carried out using the UV-Vis Spectrophotometry method, to determine the total flavonoid content. The results showed that the ethyl acetate fraction sample was positive for containing alkoloid compounds, flavonoids and did not contain saponins and tannins. The results of the assistance for spots on the TLC plate obtained an Rf value of 0.75-0.81.  the total flavonoid test results using the Uv-Vis spectrophotometry method of the ethyl acetate fraction of the red durian rind sample yielded a total flavonoid content of 5.706 mg QE/g.
KAJIAN PERBANDINGAN TABLET TAMBAH DARAH HARIAN DAN MINGGUAN PADA IBU HAMIL TERHADAP KADAR HEMOGLOBIN Yagi Dimas Nuryanto; Ana Khusnul Faizah; Effendi Rachmat
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Juli 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i1.61

Abstract

The prevalence of anemia in pregnant women is still high. According to the RISKESDAS 2018, the prevalence of anemia in pregnant women is 48.9%. The impact caused by anemia is low birth weight and bleeding in pregnant women and premature babies. Compliance in consuming daily Iron Folic Acid (IFA) is still a significant obstacle to date, so it is hoped that weekly IFA supplementation can improve compliance in pregnant women. This study aimed to determine the effect of daily versus weekly use of IFA in pregnant women on hemoglobin levels. The method used is a literature review. The search strategy used uses a database (Pubmed, Google Scholar, and Science Direct) with the keywords Pregnancy (Population), Iron supplementation (Intervention), Daily and Weekly (Comparison), and Hemoglobin (Outcome). The study obtained nine journals as study material. The nine journals showed that daily iron supplementation in non-anemic pregnant women gave better results in terms of adherence, and hemoglobin levels showed an increase that was not significantly different from daily. Weekly iron supplementation can be ensured in non-anemic pregnant women because it can increase hemoglobin levels to prevent anemia in pregnant women.
EVALUASI TINGKAT KEPATUHAN MINUM OBAT PASIEN HIPERTENSI DI PUSKESMAS KENJERAN MENGGUNAKAN METODE MMAS-8 Jala Kesit Dewayani; Ana Khusnul Faizah; Angelica Kresnamurti
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Juli 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i1.62

Abstract

Adherence is an important factor in controlling blood pressure in hypertensive patients. This study aimed to evaluate the level of medication adherence in hypertensive patients at the Kenjeran Health Center. The research method used was observational analysis with a cross-sectional design and evaluation through a questionnaire to measure the level of adherence and the MMAS-8 questionnaire to measure medication adherence. The results obtained for the level of medication adherence based on the MMAS-8 method showed that 52 patients (64%) were in the low MMAS-8 adherence category, 21 patients (26%) were in the moderate MMAS-8 adherence category, and 8 patients (10%) included in the high MMAS-8 compliance category. The conclusion of this study is that the level of adherence to medication use in hypertensive patients at the Kenjeran Health Center is at low adherence.
UJI AKTIVITAS ANTIDIARE INFUSA BIJI PAPAYA (Carica papaya) PADA MENCIT JANTAN (Mus musculus) TERINDUKSI Oleum ricini Rizka Laila Fitriyah; Ni Wayan Putri Utami; Husnul Qarina; Rizky Ayu Apriliana; Zulhi Shepiana Pasti; Nurjihad Nurjihad; Siti Rahmatul Aini
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Juli 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i1.64

Abstract

Diarrhea is a major health problem in Indonesia, and West Nusa Tenggara (NTB) is the province with the highest prevalence of diarrheal disease in Indonesia. Papaya (Carica papaya) is empirically used for the management of diarrhea. This study aims to determine the effective empirical dose of infused papaya seeds which were tested in vivo in castor oil-induced mice. This study used 5 treatment groups, namely papaya seeds infusion 1,3 g/kg body weight dan 2,6 g/kg body weight, normal control, negative control, and positive control capsule x containing guava leaf, turmeric rhizome, mojokeling fruit, and pomegranate peel extract. All groups of mice except the normal control group were induced orally with castor oil. LSIR, ALSG, and DI were measured and analyzed using the One Way Anova and post-hoc LSD tests with SPSS v.25 software. Infusion of papaya seeds (Carica papaya) has been shown to have anti-diarrheal efficacy at an empirical dose of 1.3 g/kg body weight in terms of the Average Loose Stool Grade parameter and diarrhea index comparable to capsule X.
A PHYTOCHEMICAL STUDY OF KENCUR (Kaempferia galanga L) ETHANOL EXTRACT AS ANTI-BACTERIAL, ANTI-INFLAMMATORY, ANTI-OXIDANT, AND ANTI-FUNGAL tobing, yauwan Tobing Lukiyono; Adriansyah, Agus Aan; Setianto, Budhi; Munawwaroh, Ahsantul; Ilmia, Fadhilatul; Wulansari, Febrianti; Rahmania, Almanda Putri
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Desember 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i2.76

Abstract

Kaempferia galanga L or kencur is widely used as a raw material for traditional medicine (herbal medicine), phytopharmaceuticals, the cosmetics industry, spices, as well as a mixture of sauces, cigarettes in the kretek cigarette industry. Kencur or Kaempferia galanga L has anti-inflammatory activity which has been tested in acute inflammation (Kumar, 2020)The writing of this article is based on a study of literature obtained online in the form of articles, journals and other research results. The purpose of writing this article was to determine the effectiveness of the ethanolic extract of Kaempferia galanga L using the diffusion method in order to show significant inhibition on the growth of various types of microbes at a concentration of 10 L / disc as antibacterial, anti-inflammatory, antioxidant and anti-herbal. The conclusion obtained is that kencur (Kaempferia galanga L) has many benefits ethnobotanically from kempferia galanga L, but regarding its bioactivity it proves the activity of Kampferia galanga L as antifungal, anti-oxidant, anti-inflammatory and anti-bacterial.
REVIEW ARTIKEL : ANALISIS KANDUNGAN ASAM ASKORBAT PADA BEBERAPA TANAMAN Lukman, Hilmia; Shofia, Vivi
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Desember 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i2.88

Abstract

Ascorbic acid or vitamin C is an essential organic compound for the body and has many health benefits. Vitamin C cannot be produced by the body, so it must be obtained from outside the body through food consumption. The vitamin C in plants varies considerably depending on the type, the part of the plant, and the growing environment. Vitamin C analysis can be carried out using qualitative and quantitative methods. This article review aims to review qualitative and the quantitative analysis of vitamin C using plant samples. The plants used in the study are plants that are widely consumed in Indonesia, namely matoa fruit (Pometia pinnata), water spinach (Ipomoea reptana Poir), spinach (Amaranthus spinosus), cucumber (Cucumis sativus L.), enau fruit (Arenga pinnata Merr.) and katuk leaves (Sauropus Androgynus). The qualitative analysis of vitamin C used FeCl3, KMnO4, Methylene blue and AgNO3 reagents, while the qualitative analysis uses the UV-Vis spectrophotometry method and several titration methods.

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