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Giftania Wardani Sudjarwo
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Journal of Pharmacy Science and Technology
Published by Universitas Hang Tuah
ISSN : -     EISSN : 26140993     DOI : https://doi.org/10.30649/pst
Core Subject : Health,
Medicine & Pharmacology
The Journal of Pharmaceutical Science and Technology is a journal for scientific publications on all pharmaceutical aspects including pharmaceutical science (pharmaceutical technology, pharmaceutical chemistry, pharmaceutical biology, pharmacognosy, microbiology and pharmaceutical biotechnology), community pharmacy, clinical pharmacy until explore the potential of marine biota. This journal is published twice a year to provide a means for pharmacists and other health professionals to share research results to improve the science of pharmaceuticals. The Journal of Pharmaceutical Science and Technology is intended to present the best quality research articles in pharmaceutical science, community pharmacy and clinical pharmacy to become scientific guides in fields related to science and pharmaceutical technology. This journal is a peer-reviewed journal and publishes original research articles on all aspects of science and pharmaceutical technology. This journal accepts original articles as well as for other categories such as review articles and case reports for all aspects of pharmaceutical science, pharmacy clinics and community pharmacy.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 48 Documents
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EVALUASI WAKTU TUNGGU PELAYANAN RESEP PASIEN RAWAT JALAN DI RUMAH SAKIT ANWAR MEDIKA Erviani Dinda Mahmudah Sari; Khurin In Wahyuni; Puspita Raras Anindita
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 2 Nomor 1
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v2i1.100

Abstract

The waiting time for finished drug service is the grace period from the time the patient submits the prescription until receiving the finished drug with a minimum standard set by the Ministry of Health is ≤ 30 minutes, while the waiting time for concoction drug service is the grace period from the time the patient submits the prescription until receiving the concoction drug that is ≤ 60 minutes. This study aims to determine the average waiting time for outpatient prescription services at Anwar Medika Hospital. This research was conducted with a cross sectional descriptive method. Primary data was collected through direct observation and recording of prescription service waiting times in the waiting time recording form on February 10, 2020 to February 11, 2020. Data taken were 384 outpatient prescriptions consisting of 346 non-concoctions and 38 prescription concoctions. In this study, 384 recipes were used as the research sample consisting of 346 for non-concoction recipes and 38 for recipe concoctions. The average time needed to complete a non-concoction recipe is 18.7 minutes and the time required to complete a recipe concoction is 30.9 minutes. Based on the results of research that has been done, it is found that the average waiting time for prescription services at Anwar Medika Hospital has fulfilled the requirements according to the minimum service standards at the hospital.
PENGARUH PELAYANAN KEFARMASIAN TERHADAP KEPUASAN PASIEN HIPERTENSI RAWAT JALAN DI RUMAH SAKIT ANWAR MEDIKA Rosi Maya Andriani; Khurin In Wahyuni; Puspita Raras Anindita
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 2 Nomor 1
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v2i1.102

Abstract

This study aims to determine the satisfaction of outpatient hypertension patients at Anwar Medika Hospital and to determine the effect of pharmaceutical services on outpatient hypertension patient satisfaction at Anwar Medika Hospital. This research method is an observational research with a descriptive research design using quantitative analysis. This research at Anwar Medika Hospital was conducted in March 2020. This research approach uses a survey approach where the data collection process is carried out by distributing questionnaires and interviews to respondents. For easy data processing, SPSS version 20 was used. The results of the study were 200 respondents. This study concluded that the respondents expressed very dissatisfaction with 1.2%, the respondents stated that they were not satisfied with 4.8%, the respondents stated that they were satisfied with 27.9%, the respondents stated that they were very satisfied with 66.2%. The effect of the level of pharmaceutical services on the satisfaction of hypertensive patients is y = 35.869 + 0.460x.
EFEK PENGGUNAAN KAPSUL MARINE OMEGA-3 TERHADAP KADAR TRIGLISERIDA PADA PASIEN HIPERLIPIDEMIA Ana Khusnul Faizah; Lestiono Lestiono; Amitasari Damayanti
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 2 Nomor 1
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v2i1.101

Abstract

Dyslipidemia is a lipid disorder characterized by the abnormal value in lipid in blood plasma. The objective of this study was to analyze the effect of short term marine omega-3 supplement capsules on triglyceride level in outpatients with dyslipidemia in Teaching Hospital Surabaya. This was a cohort prospective study. There were two groups, namely pre and post intervention group. The intervention group was given capsule of marine omega-3 for a month. The TG value was measured in pre and post using marine omega-3 capsule. We had 12 outpatients in every group. There were no significant difference in plasma TG level within control and intervention group (p>0.05).
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL 96% DAUN MIMBA (Azadirachta indica A. Juss. ) DENGAN METODE EKSTRAKSI PERKOLASI TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus Yanu Andhiarto; Rina Andayani; Nur Hidayatul Ilmiyah
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 2 Nomor 1
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v2i1.99

Abstract

Skin infections most often found in developing countries, especially in the tropics, are purulent skin inflammation (pyoderma), the main cause of Staphylococcus aureus. The increasing number of cases of bacteria that are resistant to antibacterial can encourage the extraction of sources of antibacterial drugs from natural ingredients. One of the plants that is thought to have the antibacterial activity of Staphylococcus aureus is the Neem plant. In this study an antibacterial activity test was carried out with the well diffusion method from 96% ethanol extract of Mimba leaves extracted by percolation method. Phytochemical screening tests obtained 96% ethanol extract of Mimba leaves containing alcaloid, saponins, tannins, steroids / terpenoids and flavonoids. The results of the study on the antibacterial activity test showed a concentration of 75% ethanol extract of 96% Mimba leaves classified as having strong activity, at a concentration of 50% and 25% classified as having moderate activity. It concluded that the three concentrations of 96% ethanol extract of Mimba leaves were able to inhibit the growth of Staphylococcus aureus bacteria.
ANALISIS KEPUASAN PASIEN RAWAT JALAN DALAM PELAYANAN RESEP DI INSTALASI FARMASI RUMAH SAKIT UMUM LIRBOYO TAHUN 2019 Djembor Sugeng Walujo; Krisogonus Ephrino S; Nurul Utami
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 2 No. 2: Desember 2021
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v3i1.106

Abstract

Health care is an essential factor in improving the health and welfare era at every insane worldwide. Patient satisfaction is a crucial problem for health care providers. This is the word-of-mouth promotion for prospective patients to expect more favorable for the operation of hospitals. This study aims to determine the patient satisfaction of BPJS participants and the general patient satisfaction in service pharmacy prescriptions in the outpatient RSU Lirboyo Kediri. The samples in this study were selected patients with the accidental sampling method as many as 85 patients and 85 patients BPJS general. The analysis was done using a questionnaire RATER method using gap test, customer window, and test independent sample t-test. The quality of pharmaceutical services that in terms of the average value of five dimensions of reliability, collateral, direct evidence, empathy, and responsiveness to patient BPJS negative gap values obtained for -0012 with patient satisfaction is less satisfied. In terms of the average value of five dimensions of reliability, guarantees, direct evidence, empathy, and responsiveness to public patients, the quality of pharmaceutical services obtained a positive gap value of 0.032 with a satisfying degree of satisfaction. Test results Independent sample t- test available significant value of 0.620> 0.05. Thus, it can be said that satisfaction outpatients and patients BPJS general users significantly no difference.
AKTIFITAS ANTIOBESITAS EKSTRAK ETANOL JAMBU MAWAR (Syzygium jambos (L.) Alston) PADA TIKUS BETINA GALUR WISTAR Atun Qowiyyah; Setiadi Ihsan; Renggana Renggana; Maila N. Khoeriyah
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 2 No. 2: Desember 2021
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Obesity prevalence has increased in recent years and has caused severe health problems. This research was carried out to obtain alternative antiobesity therapy with more minimal side effects. The antiobesity activity of rose apple (Syzygium Jambos (L.) Alston) leaves on female Wistar rats induced by high carbohydrate food for 45 days and subcutaneously injecting MSG 2 g/kg BW. Extraction was carried out using the maceration method 96% ethanol. The test parameters observed were body weight, food intake, stool consistency and weight, liver and abdominal fat tissue weight. The results showed that high carbohydrate food and monosodium glutamate could induce obesity. Ethanol extract of rose apple leaves at doses of 25, 50, and 100 mg/kg BW body weight had antiobesity activity by inhibiting body weight gain significantly compared to a positive control group (p<0.05). The highest antiobesity effect was shown by the ethanol extract of rose apple leaves at doses of 50 mg/kg BW with % inhibition of body weight gain of 169.3% to a positive control group. Ethanol extract of rose apple leaves may reduce appetite but didn’t have a laxative effect and couldn’t reduce fat deposits in the liver and abdominal fat tissue.
PENGEMBANGAN VALIDASI METODE DAN PENETAPAN KADAR AKRILAMIDA PADA UBI JALAR GORENG SECARA KROMATOGRAFI LAPIS TIPIS-DENSITOMETRI Ayik Rosita P
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 2 No. 2: Desember 2021
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v3i1.107

Abstract

A thin-layer chromatography (TLC) Densitometric method for analyzing acrylamide in fried sweet potatoes is not reported before. The research aims to determine the development of acrylamide validation and acrylamide concentration in fried sweet potatoes. The retardation factor for evaluating acrylamide uses silica gel column 254 with range 0.4-0.5 and eluate by methanol: benzene (2:1) was analyzed in a maximum wavelength of 200 nm. Linear response of acrylamide standard was tested within a 120-300 ppm concentration range, and the correlation coefficient (r) more remarkable than 0,99, detection limit 17.45 ppm and quantitative limit 52.36 ppm. Sample preparation was performed by ethanol 70%. The precision resulted from 2,67%, and this result was less than 16% (literature). Percentage of recoveries 98,18 %, and in the literature, 98%-102%. The TLC densitometric method is selective, precise, and accurate. Finally, the research showed that fried sweet potatoes contain acrylamide less than 230,32 ng samples, so the selection is very safe to consume.
KARAKTER SPESIFIK EKSTRAK DAUN YODIUM (Jatropha multifida L.) DARI TIGA LOKASI TEMPAT TUMBUH DI JAWA TIMUR Dyah Aryantini; Erni Anika Sari; Dani Nanda S.W
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 2 No. 2: Desember 2021
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v3i1.109

Abstract

Jatropha multifida L. is a plant that has many medicinal properties. The active compounds of this plant include tannins, saponins, flavonoids, and phenols. However, the content of active compounds and the quality of extracts of a medicinal plant cannot be guaranteed to be in the same amount, and this is due to the influence of different growing sites. Therefore it is essential to do standardization. This study aims to characterize iodine leaf extracts from the cities of Kediri, Nganjuk, and Madiun. Specific parameter tests include the section's identity, organoleptic, content of soluble compounds in water and ethanol 96%, and screening for phytochemical flavonoids, tannin alkaloids, and saponins. This study can be concluded that extracts from Kediri, Nganjuk, and Madiun have a thick extract form with a blackish-brown color and have a distinctive odor and bitter taste. Based on phytochemical screening, all extracts contain alkaloids, flavonoids, tannins, saponins. Furthermore, the test levels of soluble compounds in ethanol 96% from Kediri, Nganjuk, and Madiun were 74; 77.70; 73.52%, and the class of soluble compounds in water were 40.90; 31,78, 41.87%.
STUDI IN SILICO DAN HUBUNGAN KUANTITATIF STRUKTUR TERHADAP AKTIVITAS TANAMAN MANGROVE (Avicennia marina (Forssk.) Vierh.) SEBAGAI ANTIDIABETES Arinil Hidayati; Siswandono Siswandono; Pramudita Riwanti
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 2 Nomor 1
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v2i1.98

Abstract

The research is applied to 20 compounds contained into Avicennia marina which is : 4',5-dihydroxy-3',5',7-trimethoxyflavone, isorhamnetin 3-O-rutinoside, quercetin, stenocarproquinone B, avicennone C, avicennone E, avicennone F, avicennone D, 4'5-dihydroxy-3',7-dimethoxyflavone, chrysoeriol 7-O-glucoside, naphta(1,2-b)furan-4,5-dione, 3-hydroxy-naphtal (1,2-b)furan-4,5-dione, kaempferol, 5-hydroxy-4',7-dimethoxyflavone, avicequinone C, 2-[2'-(2'-hydroxy)propyl]-naphta[1,2-b]furan-4,5-dione,4',5,7-trihydroxyflavone, luteolin 7-O-methylether, luteolin 7O-methylether 3'-O-beta-D-glucoside,5,7-dihidroxy-3',4',5'-trimethoxyflavone which are expected to have an effect as antidiabetics agent. It is undertaken to find out the linier or nonlinier relationship of the structure activity (QSAR), the physicochemical characters (lipophilic, electronic, and steric) to the activitychanging (rerank score). Moreover, it is also undertaken to find out which one of those 20 Avicenia marina compounds are predicted to possess the activity as the best antidiabetics agent by the comparison of pioglitazon. It is arranged through computerized methods through some progrmas such as used to make prediction of the activity by using Molegro Virtual Docker 20`11.5.0.0 from CLCBio. by using the peroxisome proliferator-activated receptor-gamma (PPAR) in code of PDB : 2XKW. The compound of isorhamnetin 3-O-rutinoside, , chrysoeriol 7-O-glucoside, dan senyawa luteolin 7-O-methylether 3'-O-beta-D-glucosdie are predicted to have the best antidiabetics agent if it is compared with comparing drug pioglitazon.
ANALISIS PENGGUNAAN GLIBENKLAMID DAN GLIMEPIRID BERDASARKAN PERESEPAN OBAT MENGGUNAKAN METODE ATC/DDD) Elva Asmiati; Shafelia Nata Aji Kusuma; Ika Ratna Hidayati; Rizka Novia Atmadani
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 3 No. 1: Juli 2022
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v3i1.32

Abstract

Diabetes Mellitus is a non-contagious disease in which insulin cannot be produced optimally by the pancreas, characterized by hyperglycemia. Glibenclamide and glimepiride are sulfonylurea antidiabetic drugs. To analyze the use of Glibenclamide and Glimepirid drugs at the Sekupang Public Health Center in 2020 using the ATC/DDD method. The result of DDD/1000 KPRJ/Day Glibenclamide 5 mg was 10.29 mg for the highest on April, and the lowest was 0.57 mg on February. The one-year average was 2.97 mg. The result of DDD//1000 OPV/Day Glimepiride 2 mg was 16.80 mg is the highest on February, and the lowest was 2.79 mg on June. The one-year average was 6.77 mg. The results of DDD/1000 KPRJ/Day Glimepiride 4 mg were highest on October 23,48 mg, and the lowest was on January 3.45 mg, with 13.15 mg average per year. The one-year average of DDD value of Glibenclamide 5 mg does not surpass the 10 mg WHO DDD value, so it can be concluded that the use of Glibenclamide has not been widely used in the community. For Glimepiride 2 mg and 4 mg, the DDD value obtained exceeds the WHO DDD value of 2 mg, it can be concluded that Glimepirid is widely used in the community.

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