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All Journal Pharmaciana: Jurnal Kefarmasian MUDARRISA Indonesian Journal of Islamic Education Studies Jurnal Biologi Tropis Indonesian Journal of Chemistry PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Social, Humanities, and Educational Studies (SHEs): Conference Series Pena : Jurnal Ilmu Pengetahuan dan Teknologi Jurnal Pengabdian kepada Masyarakat Nusantara Jurnal Insan Farmasi Indonesia Jurnal Farmasi Sasambo Journal of Pharmacy PENA ABDIMAS : Jurnal Pengabdian Masyarakat Jurnal Pengabdian Ilmu Kesehatan Journal of Pharmacy Science and Technology Benzena Pharmaceutical Scientific Journal Joong-Ki Medical Sains : Jurnal Ilmiah Kefarmasian Baktimu : Jurnal Pengabdian Kepada Masyarakat Joong-Ki Baktimu : Jurnal Pengabdian Kepada Masyarakat
Mahfur, Mahfur
Program Studi S1 Farmasi, Fakultas Farmasi, Universitas Pekalongan, Pekalongan, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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KONSEP PENDIDIKAN ISLAM MENURUT MOHAMMAD NATSIR Mahfur Mahfur
MUDARRISA: Jurnal Kajian Pendidikan Islam Vol 1, No 2 (2009)
Publisher : Prodi PGMI IAIN Salatiga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (399.042 KB) | DOI: 10.18326/mdr.v1i2.185-210

Abstract

The research objectives of this research are: (1) What is the concept Mohammad Natsir of Islamic education?, (2) What are the cornerstone concept of thought Mohammad Natsir in Islamic education?, (3) How relevant is the idea Mohammad Natsir on the thinking of Islamic education in Indonesia today?. To answer these questions, this study used literature research. Because here is a literature review of research, the author examines the concept of thought in Mohammad Natsir with the help of books in his own writings as well as books written by others that tell about the Islamic educational thought by Mohammad Natsir. The results showed that the concept Mohammad Natsir of Islamic education that Education should be able to bring man achieve his goal, which devote themselves to God, having good character (akhlakul karimah) and got a decent living in the world. While the foundation of Islamic education is to know God, to acknowledge the ones of God and not to consider as an ally of Him. Relevance thought Mohammad Natsir to education in Indonesia today, as evidenced by the existence of public schools and Islamic school (madrasah), even schools that combine general education and religious education, as well as coordination among the schools with the holding of the National exam together.
UJI SITOTOKSIK FRAKSI ETIL ASETAT EKSTRAK ETANOL AKAR PASAK BUMI (eurycoma longifolia jack) TERHADAP SEL KANKER T47D DENGAN METODE 3-(4,5 dimetiltiazol -2-il)2,5 difenil tetrazolium bromide (MTT) Mahfur Mahfur
Pena Jurnal Ilmu Pengetahuan Dan Teknologi Vol 30, No 2 (2016): Pena September 2016
Publisher : LPPM Universitas Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31941/jurnalpena.v30i2.497

Abstract

Cancer is one of the leading causes of death in the world, there were 14.1 million cancer cases and 8.2 million of them cause deaths occurred in 2012. The data from BPJS, in January-June 2014 were reported for outpatient treatment of cancer ranks second with 88.106 the number of cases, while for inpatient ranks 5th, with the number of 56.033 cases. Of the many types of cancer, breast cancer is a common malignancy and a major cause of death in women. Chemotherapy is a cancer treatment using a drug that destroy cancer cells. Anticancer drugs in question are cytotoxic drug (a chemotherapeutic agent) such as taxol, bleomycin, doxorubicin, 5-flurourasil, chlorambucil. The actifity of cytotoxic drug is not selective, because they are either toxic to cancer cells and normal cells. Other treatments that can be used to terapy of cancer is using natural product. Eurycoma longifolia Jack is one plant native of Indonesia which has anti-cancer potential. One of The compounds that have the ability cytotoxic is euricomanone. This study aims to determine Cytotoxic effects of ethyl acetate fraction ethanol extract of Eurycoma longifolia Jack to T47D cancer cells by the method of MTT. The sample used are the roots of Eurycoma longifolia Jack, as much as 500g sample were extracted with ethanol. The extract obtained is then fractionated using ethyl acetate solvent. The fractions obtained tested cytotoxic ability by the method of 3- (4,5 dimetiltiazol -2-yl) - 2,5 diphenyl tetrazolium bromide (MTT) to determine IC50 value. The yield resulting from the extraction process was 2.99% or 14,95 g. ethyl acetate soluble fraction amounted to 19.73% from the totally extract. MTT assay results showed IC50 ethyl acetate fraction of ethanol extract Eurycoma longifolia Jack at 340 µg / ml
Profil Metabolit Sekunder Senyawa Aktif Minyak Atsiri Jinten Hitam (Nigella sativa L.) dari Habasyah dan India Mahfur Mahfur
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 15 No. 01 Juli 2018
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pharmacy.v15i1.2274

Abstract

Nigella sativa L. atau yang biasa disebut jinten hitam, jinten ireng, black cumin, merupakan tanaman asli dari Eropa Selatan yang mempunyai beragam kandungan. Tanaman ini tumbuh di berbagai belahan dunia tetapi paling banyak ditemukan di daerah Timur Tengah, Asia, dan Afrika. Tanaman jinten hitam mempunyai banyak manfaat bagi dunia pengobatan. Secara historis, biji jinten hitam telah digunakan di era Mesir Kuno dan diresepkan oleh dokter Yunani untuk mengobati sakit kepala, hidung tersumbat, sakit gigi, cacing usus, diuretic, dan untuk meningkatkan produksi susu. Aktifitas farmakologi biji jinten hitam adalah antibakteri, antioksidan, antitumor, anti- inflamasi, sitotoksik, dan imunostimulan. Mutu dari minyak atsiri Nigella sativa dapat dilihat dari kelengkapan metabolit sekunder aktifnya. Industri herbal tanah air Indonesia kebanyakan mendapat sumber bahan baku yang berasal dari India dan Habasyah. Perbandingan jinten hitam dari berbagai daerah tersebut menjadi salah satu faktor yang mempengaruhi kualitas sediaan minyak atsiri jinten hitam. Oleh karena hal tersebut, maka perlu dilakukan penelitian yang melihat kandungan metabolit sekunder aktif dari jinten hitam yang berasal dari India dan Habasyah. Penelitian ini merupakan penelitian deskriptif, dimana sampel yang digunakan didapat dari distributor, kedua sampel tersebut berasal dari Habasyah dan India. Biji jinten hitam dari Habasyah dan India didestilasi terlebih dahulu menggunakan metode destilasi uap dan air. Minyak atsiri yang didapat dianalisis metabolit profilnya dengan menggunakan GC-MS. Hasil penelitian menunjukkan biji jinten hitam dari Habasyah dan India mempunyai kelengkapan metabolit sekunder aktif yang sama, akan tetapi kadar dari masing-masing metabolit sekunder berbeda.
MULTIVITAMIN SEBAGAI UPAYA PENCEGAHAN STUNTING DAN PERTOLONGAN PERTAMA PADA ANAK TERSEDAK DI DESA KARANGANYAR BATANG Mahfur Mahfur; Anik Indriyono
PENA ABDIMAS : Jurnal Pengabdian Masyarakat Vol 4, No 1 (2023): Januari 2023
Publisher : LPPM Universitas Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31941/abdms.v4i1.2816

Abstract

Karanganyar adalah salah satu desa di Kabupaten Batang dengan luas wilayah yang tidak terlalu  luas akan tetapi jumah balita yang dimiliki tergolong tinggi. Pemerintah desa sangat aktif dalam melaksanakan program program yang berkaitan dengan tingkat kesehatan kepada masyarakat. Kegagalan pertumbuhan dapat disebabkan oleh kurangnya asupan gizi dalam seribu hari pertama kehidupan. Kondisi kegagalan pertumbuhan tersebut dapat dilihat dari anak tampak lebih pendek dibandingkan anak seusianya. Kondisi demikian dinamakan stunting. Stunting dialami pada tiga dari sepuluh anak balita. Tersedak merupakan kondisi gawat darurat yang harus cepat di tangani, bila terlalu lama akan mengakibatkan kekurangan oksigen dan mengakibatkan kematian karena kondisi tersumbatnya saluran pernafasan oleh benda asing yang berupa makanan, mainan, dan lain-lain (Putra, 2015). Tujuan dan target spesifik kegiatan ini adalah untuk menambah pehaman masyarakat desa karanganyar tentang penggunaan multivitamin sebagai upaya untuk penanggulangan stunting dan pertolongan pertama pada anak tersedak. Masyarakat lebih mengetahui berdasarkan pretest dan postest dengan hasil yang signifikan. Hasil yang diperoleh menunjukan bahwa terdapat penambahan pengetahuan dari para peserta pengabdian kepada masyarakat berkaitan dengan multivitamin, stunting, dan pertolongan pertama kasus tersedak, yang ditunjukan dari peningkatan nilai pos-test dan pre-testKata Kunci : desa Karanganyar, multivitamin, tersedak, stunting
mprovement of Speaking Skills Sending Responses through Image Assistant Talking Stick Model in Class III Students of SDN Rimbukidul 1, Karangawen District, Demak Regency Mahfur Mahfur
Social, Humanities, and Educational Studies (SHES): Conference Series Vol 4 (2021): Social, Humanities, and Educational Studies (SHEs): Conference Series (Special Issue 1
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (525.659 KB) | DOI: 10.20961/shes.v4i5.65958

Abstract

Tujuan penelitian ini adalah untuk meningkatkan keterampilan berbicara melalui model talking stick dengan bantuan media gambar pada peserta didik kelas III SDN Rimbukidul 1 Demak. Mendeskripsikan peningkatan aktivitas peserta didik kelas III SDN Rimbukidul 1 Demak dalam pembelajaran keterampilan berbicara bahasa Indonesia. Mendeskripsikan peningkatan keterampilan berbicara peserta didik kelas III SDN Rimbukidul 1 Demak dalam pembelajaran keterampilan berbicara bahasa Indonesia. Hasil penelitian menunjukkan bahwa aktivitas peserta didik siklus I memperoleh skor rata-rata 2,6 dalam kategori baik dan siklus II memperoleh rata-rata 3,24 dalam kategori sangat baik. Pada siklus III diperoleh rata-rata 3,66 dengan kategori sangat baik. Hasil belajar peserta didik pada siklus I persentase ketuntasannya sebesar 44%. Siklus II persentase ketuntasan mencapai 72%. Siklus III persentase ketuntasan mencapai 100%. Kesimpulan akhir dari hasil belajar menggunakan metode tongkat bicara adalah adanya peningkatan peserta didik di SDN Rimbukidul 1.
Comparison of the total phenolic and flavonoid contents of Amomum compactum Sol. Ex Maton from districts Linggo Asri and Paninggaran, Pekalongan Regency Mahfur Mahfur; Kharismatul Khasanah; Metha Anung Anindhita; Safira Galuh Chandra; Alfiana Nur Hidayah
Sasambo Journal of Pharmacy Vol. 4 No. 1 (2023): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v4i1.212

Abstract

Cardamom (Amomum compactum Sol. Ex Maton) is one of the largest contribution in biopharmaceutical production plants in Indonesia that is equal to 12.22% and yield reaching 105.735 kg/year in Pekalongan Regency. The largest cardamom production in Pekalongan Regency is in 2 districts, namely Linggo Asri and Paninggaran. Cardamom is used in traditional medicines, because it has chemical compounds such as flavonoids and phenolics. The aim of this study was to compare total flavonoids and total phenolics content in Amomum compactum Sol. Ex Maton extract originates from Linggo Asri and Paninggaran district, Pekalongan Regency. The samples were extracted by water extraction, and then phytochemical contents were identified with HCl and FeCl3 reagent. The samples were calculated of total flavonoids and total phenolics content by spectrometric using aluminum chloride colorimetric assay and Folin–Ciocalteu method. The result showed a significant difference in the levels of total phenolic content between Amomum compactum Sol. Ex Maton extract origin from Linggo Asri district 41.43±0.54 µg/mg and Paninggaran district 120.55±1.89 µg/mg, but it was not found in total flavonoid content where from Linggo Asri district 289.06±4.1 µg/mg and Paninggaran district 303.81±0.5 µg/mg. The conclusion is Amomum compactum Sol. Ex Maton extract originates from Linggo Asri and Paninggaran district of Pekalongan city showed a significant difference in the levels of total phenolic content, but it was not found in total flavonoid content.
OPTIMASI WAKTU FERMENTASI JAMUR SIMBION DARI SPONGE Rhabdastrella SP. DAN UJI AKTIVITAS ANTIBAKTERINYA Mahfur Mahfur; Khafidz Mahbub; Nada Safira Salsabila; Maulida Nur Istiqomah
Jurnal Insan Farmasi Indonesia Vol 6 No 1 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i1.1333

Abstract

Sponges are known have many metabolites compounds and potential to be used as raw materials for medicines. spongesare have the ability to form symbiosis with microorganisms. Rhabdastrela sp is have to contain various secondary metabolites, especially the Triterpenes group. The fermentation process is a method to produce abundant secondary metabolite from microorganisms such as symbiont fungi. This study aims to determine the optimal fermentation time for the symbiont fungus Rhabdastrella sp. by looking at the secondary metabolites produced and their antibacterial activity. This research is included of experimental research. Cultivation of the sponge Rhabdastrella sp. for the growth of symbiont fungi. Followed by a fermentation process with variations in time with 2,4,6,8,10,12, and 14 days to get the secondary metabolites produced. Liquid liquid extraction was carried out to obtain secondary metabolites. The final stage is TLC profile and test the antibacterial activity of extract using the well-diffusion method. The results showed that the long fermentation time affected the secondary metabolites obtained, and their antibacterial activity. The profile of secondary metabolites showed that the 12th day of fermentation had the most complex secondary metabolites and the highest yield and had a clear zone of 12.5 ± 0.26 mm.
SKRINING FITOKIMIA DAN ANALISIS KADAR FLAVONOID TOTAL FRAKSI ETIL ASETAT KULIT BUAH DURIAN MERAH (Durio graveolens Becc.) Dengan METODE SPEKTROFOTOMETRI Uv-VIS : SKRINING FITOKIMIA DAN ANALISIS KADAR FLAVONOID TOTAL FRAKSI ETIL ASETAT KULIT BUAH DURIAN MERAH (Durio graveolens Becc.) Dengan METODE SPEKTROFOTOMETRI Uv-VIS Tri Esti Kusuma Bakti; Mahfur Mahfur
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Juli 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i1.57

Abstract

Flavonoids are natural compounds found in durian. One of the most important components known as natural compounds, which have the potential as anti-inflammatory and antioxidant. The secondary metabolites of flavonoids in the skin of plants can be affected by the process of photosynthesis. The purpose of this study was to measure the total flavonoid content and ethyl acetate fraction of red durian skin using the Uv-Vis spectrophotometry method. This research uses a type of descriptive research method. Extraction of red durian fruit skin (Durio graveolens Becc) using maceration method with 70% ethanol solvent. Fractionation was carried out using the liquid-liquid fractionation method using ethyl acetate. Thin Layer Chromatography (TLC) was used to identify flavonoids with the stationary phase of silica gel GF254 and the mobile phase of methanol:ethyl acetate 7:3 for flavonoid compounds. Quantitative analysis was carried out using the UV-Vis Spectrophotometry method, to determine the total flavonoid content. The results showed that the ethyl acetate fraction sample was positive for containing alkoloid compounds, flavonoids and did not contain saponins and tannins. The results of the assistance for spots on the TLC plate obtained an Rf value of 0.75-0.81.  the total flavonoid test results using the Uv-Vis spectrophotometry method of the ethyl acetate fraction of the red durian rind sample yielded a total flavonoid content of 5.706 mg QE/g.
Skrining Fitokimia Dan Uji Kadar Kurkumin Pada Fraksi Etil Asetat Rimpang Kunyit (Curcuma Longa) Dengan Metode Klt Dan Spektrofotometri Uv-Vis Aprilya Kumala Shary; Mahfur Mahfur
Pena: Jurnal Ilmu Pengetahuan dan Teknologi Vol 37, No 2 (2023): PENA SEPTEMBER 2023 (ARTICLE IN PRESS)
Publisher : LPPM Universitas Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31941/jurnalpena.v37i2.3080

Abstract

Turmeric (Curcuma longa) is a medicinal plant from the Zingiberaceae family which has the potential to be developed as a superior plant that has benefits and efficacy as a medicinal ingredient. Turmeric has a yellow dye called curcuminoids as much as 5% (50-60% curcumin, demethoxycurcumin and bisdemethoxycurcumin). The very basic content of turmeric is Curcuma or curcumin because it has the largest component. The purpose of this study was to determine the phytochemical content by conducting a screening test on the ethyl acetate fraction of turmeric rhizome using the TLC method and UV-Vis Spectrophotometry. This research method used descriptive method by means of observation or non-experimental. Phytochemical screening included tests for flavonoids, alkaloids, saponins, phenols, tannins and steroids/triterpenoids which carried out to determine the class of compounds contained in turmeric rhizome. The ethyl acetate fraction in turmeric rhizome suspected to contain curcumin, so a test for the levels of curcumin contained in turmeric rhizome was carried out. The results showed that the positive turmeric rhizome samples contained flavonoids, tannins, phenols and steroids. As well as negatively contain alkaloid compounds and saponins. The results of identification with TLC samples containing curcumin compounds according to the literature and the standard Rf value of curcumin is 0.75-0.80. The assay results using the UV-Vis Spectrophotometry method for the ethyl acetate fraction of turmeric rhizome samples yielded an average concentration of 159.79 mg⁄g.
Penyuluhan Dagusibu Kepada Dharma Wanita Pekalongan Barat Musa Fitri Fatkhiya; Muhammad Walid; Mahfur Mahfur
Joong-Ki : Jurnal Pengabdian Masyarakat Vol. 3 No. 1: November 2023
Publisher : CV. Ulil Albab Corp

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56799/joongki.v3i1.2607

Abstract

DAGUSIBU (Dapatkan, Gunakan, Simpan, dan Buang) adalah jenis program yang membahas terkait pengelolaan obat dengan baik dan benar yang diusung oleh Apoteker di seluruh Indonesia yang bertujuan untuk mengurangi kejadian atau kasus penyalahgunaan obat yang kerap terjadi di Indonesia. Pengetahuan terkait DAGUSIBU perlu diketahui oleh seluruh kalangan Masyarakat baik anak-anak, remaja ataupun dewasa khususnya pengetahuan yang baik dari seorang ibu rumah tangga. Masyarakat mendapatkan obat melalui resep dokter ataupun obat bebas dan obat bebas terbatas yang dapat dibeli tanpa resep dokter. Kegiatan ini bertujuan untuk meningkatkan pengetahuan ibu Dharma Wanita Pekalongan Barat terkait DAGUSIBU. Metode yang digunakan adalah ceramah dan diskusi. Kegiatan dilakukan di kelurahan Podosugih Kota Pekalongan pada tanggal 8 Agustus 2023 dan dihadiri sebanyak 50 peserta ibu-ibu dari Dharma Wanita Pekalongan Barat. Diharapkan melalui kegiatan ini, pengetahuan terkait pengelolaan obat dapat meningkat dan Masyarakat dapat mengimplementasikan secara langsung.
Co-Authors Abdul Aziz, Danang Achada, Dina Alfiana Nur Hidayah Ananda, Luthfiah Andre Kurniawan Anik Indriono Anik Indriyono Aprilya Kumala Shary Bintang Pratama, Kevin Dika, Ika Vina Ekayanti, Nonik Nur Erin Efrilia Evi Ulfiani , Riska Farchan Mushaf Al Ramadhani Fatkhiya, Musa Fitri Harwati, Wiwik Hasnawati Hasnawati Hery Ardianto Hidayah Syaro Abesah, Nur Hidayatullah, Adib Husain, Khafidz I Made Wisnu Adhi Putra Ilma Faza, Febi Julian, Rixzal Azis Julian, Rixzal Aziz Khafid Mahbub Kharismatul Khasanah Kitia Rani mahbub, khafid Maliah, Nabilatun Maulida Nur Istiqomah Maulidya, Dina Achada Metha Anung Anindhita Mochammad Ardy Wiyono Mohamad Ramzi Arkanie Muhammad Walid Muhammad Walid Mulyanti Shofaro Nada Safira Salsabila Nathania, Jacinda Caroline Nila Oktaviani noni Nur Ekayanti Nunung Hasanah Nur Ermawati, Nur Nyoman Suarjana Puji Nurhayati Quintanuha Meisa, Salsabiela Rizki Nur Fadilah Rohmah, Salis Alyatur Rohmaniah, Salis Alyatur Safira Galuh Chandra Salsabiela Quintanuha Meisa Salsabila Hanifatul Ariqoh Siska Rusmalina Sukma Sona Tri Esti Kusuma Bakti Wiyono, Mochamad Ardy