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Journal of General Procedural Dermatology and Venereology Indonesia
Published by Universitas Indonesia
ISSN : -     EISSN : 24607991     DOI : https://doi.org/10.19100/jdvi.v1i1.8
Core Subject : Health,
Medicine & Pharmacology
Journal of General-Procedural Dermatology & Venereology Indonesia is an open access and peer-reviewed journal that focuses on dermatology and venereology. This journal publishes original articles, reviews, case reports, and brief communications which contain short features of medicine, current developments in diagnostic procedures, treatments, or other health issues that are relevant and important.
Arjuna Subject : Kedokteran - Dematologi
Articles 164 Documents
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Serial Excision of a Nevus Sebaceous of Jadassohn on the Scalp Sugiatno, Belladikna Brillianty; Widiatmoko, Arif; Dani, Adinda Amalia; Retnani, Diah Prabawati
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 9, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: Nevus sebaceous of Jadassohn (NSJ) is a non-hereditary hamartoma of the skin’s adnexal structures. The incidence of NSJ in newborns is estimated at 0.1-0.3% with no gender or ethnic propensity. Surgical excision is a common treatment for NSJ, although there is no definite consensus on the timing or recommendations for the removal. This article aims to present the advantages of serial excision therapy in a case of NSJ. Case Illustration: A 14-year-old male presented with a complaint of a bump on the scalp since birth, which had progressively enlarged during puberty. Dermatological examination revealed a well-demarcated, yellow-orange verrucous plaque with irregular borders measuring 3x3.5 cm. The diagnosis was confirmed through dermoscopy and histopathology. The patient underwent a three-stage serial excision at 3-4-week intervals. Discussion: The excision technique for NSJ excision was selected based on the location and size of the lesion. Serial excision is a widely used and straightforward method. This method was chosen due to the lesion’s large area. However, NSJ excision on the scalp presents its own challenges due to limited soft tissue flexibility, hair-bearing skin, and a convex surface, which may affect reconstruction outcomes. Conclusion: The three-stage serial excision resulted in complete removal of the NSJ, minimal scarring without significant alopecia, and no recurrence during the 6-month follow-up.
Psoriasis Genomics: A Review Hutasuhut, Magna; Budianti, Windy Keumala; Indriatmi, Wresti; Setyorini, Mirawati
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 9, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: Psoriasis is a dermatological condition influenced by genetic and epigenetic factors, environmental triggers, as well as immune responses. Genomics refers to the study of individual genes (genomes) and their interactions with environmental influences. In the context of psoriasis genomics, the interplay between genetic predisposition and environmental factors contributes to the manifestation and variations of the disease. With advancements in molecular genotyping technology and genome-wide association studies (GWASs), researchers have identified 50 genetic markers linked to psoriasis. Discussion: Several genetic loci associated with psoriasis have been identified, including PSORS 1-15. The genetics of psoriasis is also linked to its onset, precipitating factors, associated comorbidities, and clinical variations. Advances in psoriasis genomics are leading to more targeted and innovative treatment approaches. The latest therapeutic developments for psoriasis mainly focus on the interleukin-23 (IL-23)/T-helper 17 (Th17) pathways. Conclusion: The development of GWASs provides new knowledge about psoriasis, including its pathogenesis and specific treatments.
Effectiveness of 5% Channa Striata Extract Gel in Wound Healing: A Double-blind Randomized Controlled Trial Yahya, Yulia Farida; Kurniawati, Yuli; Bahar, Erial; Toruan, Theresia Lumban; Kartowigno, Soenarto; Purwoko, Muhammad Izazi Hari; Octyvani, Tiar Marina
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 9, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: Snakehead fish (Channa striata, CS) has traditionally been used in Indonesia as a nutrient to promote wound healing. It contains protein highly similar to human protein, which may be involved in wound healing via biological pathways. We aim to determine the effectiveness of the topical 5% CS extract gel in promoting wound healing. Methods: A double-blind, placebo-controlled randomized clinical trial was conducted from June to August 2022 at the Department of Dermatology, Venereology, and Aesthetics of Dr. Mohammad Hoesin Hospital. We allocated 32 post-skin surgery participants with grade I acute superficial wounds on the face, neck, trunk, and extremities into 2 groups with one receiving 5% CS (n=16) and the other receiving placebo (n=16). Both groups applied the treatments twice daily. Assessments of wound healing using modified REEDA (redness, edema, ecchymosis, drainage, approximation) score, wound size, and adverse effects were done at follow-up days 1, 3, and 7. Results: Both groups showed REEDA score improvements on days 1, 3, and 7, with significant difference between both groups identified on day 3 (p=0.038). Wound size improved at each follow-up in all participants, with the 5% CS group being slightly better than the placebo group on day 3 (p>0.05). A mild adverse event was found in only one participant in the 5% CS group (3.1%). Conclusion: Both 5% CS extract gel and placebo had good safety profile and were effective in promoting wound healing. 5% CS extract gel was better at reducing REEDA score.
Skin Rejuvenation with Microbotox: A Review Malinda, Ifen Ayu; Jusuf, Nelva Karmila
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 9, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: Skin aging is characterized by a gradual loss of tissue and organ function. Skin aging can be classified into two types: intrinsic aging, associated with the aging process itself, and extrinsic aging, which is linked to external factors. Microbotox—an intradermal injection of diluted botulinum toxin—has emerged as a promising technique for rejuvenation by improving skin texture, pore size, and sebum control. This review aims to provide a comprehensive overview of the microbotox technique in the context of skin aging, emphasizing its mechanisms, indications, and clinical outcomes. Discussion: In Asia, intradermal injection of botulinum toxin or microbotox has been widely adopted. The technique involves injecting microdroplets of onabotulinumtoxin type A (ONA) into the intradermal layer at lower concentrations compared to conventional methods. Microbotox is highly sought after for its ability to improve skin texture, address enlarged pores, control sebum, and rejuvenate the skin without the stiffness often associated with conventional botox. Conclusion: Microbotox provides multiple dermatological benefits, including improved skin texture, pore reduction, oil control, and fine line softening, with minimal side effects. As an intradermal technique, it offers a safer and subtler alternative to traditional botox. It provides rapid results lasting up to 3-4 months, making it a valuable tool in aesthetic dermatology. This has made microbotox one of the most popular skin rejuvenation treatments today.

Page 17 of 17 | Total Record : 164

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