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Journal of Pharmaceutical and Sciences.

jps
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Published by Universitas Tjut Nyak Dhien

ISSN : - EISSN : 26563088 DOI : https://doi.org/10.36490/journal-jps.com

Core Subject : Health, Science, Agriculture, Engineering,

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, Medicinal Chemistry, Molecular Pharmacology, Novel drug delivery system, Nanotechnology, Analytical Chemistry, Organic Chemistry, Natural Chemistry, Polymer Sciences, Clinical Pharmacy, pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, government policies related to pharmacy, pharmaceutical care, Medical Biotechnology, Biochemistry, food chemistry, health and applied sciences relevant to the field of pharmacy. Journal of Pharmaceutical and Sciences (JPS) accepts manuscripts in Indonesian Language (Bahasa Indonesia) with titles and abstracts in bilingual, both Indonesian and English. We accept article manuscripts in the form of original research, literature reviews, and systematic reviews. We do not accept articles in the form of case reports

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)

Articles 616 Documents

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Perbandingan Aktivitas Antioksidan Infusa dan Dekokta Tanaman Galling (Cayratia trifolia (L.) Domin) Angel Mangiwa; Mirna Maulidah; Tipalmaton R Patulen; Dhea K Kende; Ismail Ismail; Desy A Lestari; Maulita Indrisari; Lukman Muslimin
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

The number of patients with neurodegenerative disorders increased, especially in the productive age. The neurodegenerative disorder can be prevented by synthetic and natural antioxidants such as from plants. The herb of galling, Cayratia trifolia (L.) Domin), has long been traditionally used to prevent degenerative diseases by drinking decoction. The current study aimed to compare the antioxidant capability between infusion and decoction of galling against DPPH. The herbs were extracted with two methods, namely infusion, and decoction. This study used 7 different serial concentrations ranging 7.81 till 500 µg/mL, while the optical density was recorded at 515 nm using a spectrophotometer. The results demostrated that both infusion and decoction have antioxidant activity against DPPH with IC50 values of 87.55±1.01 (strong category) and 65.38±2.26 µg/mL (strong category), respectively. There was a statistically significant (p<0.05) between the IC50 values of infusion and decoction. In conclusion, galling is efficacious as an antioxidant source for preventing and treating degenerative diseases.

Uji Cemaran Bakteri E. coli dan Salmonella sp. Pada Daging Sapi Di Pasar Tradisional Kecamatan Hamparan Perak Silvi Eka Putri; Kurniawan Sinaga; Alfath Rusdhi
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Indonesian people prefer beef as a source of meat. More production and focus on high quality beef to meet the increasing demand for beef. The purpose of this study was to ascertain whether beef at the local market in Hamparan Perak District was contaminated with Salmonella sp. and E. coli. This research was conducted in January and February 2023 and is a descriptive study. Five samples of beef sold at the Klumpang Inpres Market, Hamparan Perak District, were used in this study. The findings revealed 18 bacterial isolates, most of which were round with intact edges, most of which were flat in height, and almost all of which were white. Seller 3 has the largest total number of microorganisms with a sample number of PS3 4.8 106 CFU / g, while seller 5 has the lowest number of PS5 samples 1.3 106 CFU / g. Contamination test results for Salmonella sp. and E.coli showed that all meat samples tested positive for Salmonella sp. and E. coli. A total of 4 isolates of gram-positive bacteria with purple color were found in the findings of bacterial staining, while there were 14 isolates of gram-negative bacteria with red and pink colors.

Perbandingan Efektivitas dan Keamanan Obat Flutikason dan Amoksisilin dalam Mengatasi Sinusitis Akut pada Anak-Anak: Sebuah Tinjauan Sistematik Mini Munir Alinu Mulki; Eriyanti Astika; Sulistiawati Sulistiawati; Aldila Divana Sarie; Anisa Aula Rahma; Fikri Aldebaran Misbah Azizi; Karlina Dwi Samratul Jannah
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Acute sinusitis (AS) can be defined as inflammation of the nose due to infection of the preanal sinus. Sinusitis is a common condition that occurs in children. Children experience an average of 6-8 colds per year with 0.5-5% developing acute sinusitis infection. Nasal corticosteroid drugs that are often used for sinusitis therapy are fluticasone. Not only that, antibiotic class drugs can also be used for the treatment of acute sinusitis, one of which is amoxicillin. The purpose of making this systematic review is to determine the effectiveness and combination of fluticasone and amoxicillin drugs in dealing with acute sinusitis treatment problems. The literature search was conducted electronically at PUBMED and was in accordance with the protocol made by PRISMA in conducting this systematic review. The literature search was conducted electronically for articles published in the last 10 years (from January 2013 to May 2023) and specific keywords 1. "acute sinusitis", OR 2. "fluticasone", OR 3. "amoxicillin", AND 4. "children" were used in the search. Inclusion criteria included experimental study design (randomized controlled trial). Articles were excluded according to case-control, cohort or qualitative study types. The data to be retrieved were the study population, type of intervention performed, study design, control variables, as well as the conclusions of the study. The article found 22 journals in the search strategy. In the end, there were 3 journals that met the eligibility criteria and were included in this systematic review. The three studies explained that the combination of fluticasone and amoxicillin had a more effective effect than monotherapy.

Review Article : Daun Jamblang (Syzygium cumini L.) Digunakan Sebagai obat Himyatul Hidayah; Refriyanti Irma; Tasya Putri Pratiwi; Elista Indah Susanti
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Jamblang (Syzigium cumini L) is a plant that almost all parts of the plant have many benefits including the leaves. Jamblang leaves contain compounds such as flavonoids, antioxidants, alkaloids, tannins, quercetin, myricetin, kaempferol, polyphenols, quinones, Lupeol, 12-oleanen-3-ol-3β-acetate, Stigmasterol, ß-sitosterol, terenoid, ß-sitosterol, Betulinic. acid, flavonol which has medicinal properties. This study aims to determine the usefulness or efficacy of jamblang leaves as medicine. This research method uses the type of Literature Review Article research with database results taken from various articles via Google Scholar, Sciendirect, and Pubmed. The results of various studies show that jamblang leaves have medicinal properties as antioxidants, anti-diarrhea, antimicrobial, anti-fungal, antihyperuremic, cariovascular, larvicidal and anti-inflammatory.

Review Article: Penggunaan Nanopartikel Kitosan sebagai Penghantar Obat Baru Iin Lidia Putama Mursal; Ainun Maratus Putri Warsito; Dyah Kharisma Ariyanti; Elista Indah Susanti; Refriyanti Irma
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Nanoparticle technology is beneficial as a drug carrier is high stability, and high carrier capacity. This carrier system can be designed to allow continuous drug release from the matrix, a polymer used for the formation of nanoparticles, one of which is chitosan. Chitosan is a polymeric substance that is used to form nanoparticles. The research method used is to review articles from several Google Scholar databases, ScienceDirect, pubmed. The advantage of chitosan is that processing it into nanoparticles allows chitosan to be used as a more effective delivery agent for pharmaceutical compounds or drugs.

Pengembangan Berbagai Metode Analisis Kadar Natrium Siklamat Pada Minuman Ringan Vriezka Mierza; Isyana Salsabila; Chalisya Vanya Advaita; Alfina Oktavianti; Sri Rahayu
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Sodium cyclamate is an artificial sweetener that is often circulated in the community. Sodium Cyclamate has the advantage of a higher sweetness level ± 30 times that of cane sugar or sucrose at a price that is relatively more affordable than natural sweeteners. However, excessive use of cyclamate can cause health problems. The maximum level of cyclamate use regulated in Permenkes 772/Menkes/Per/IX/88 is 3g/L for food and beverages. This article review aims to find out the various methods that can be used in determining the level of sodium cyclamate in soft drinks. The method used in this article review is a literature study with primary data in the form of national journals from the Google Scholar databases that have inclusion and exclusion criteria. The keywords used in the literature search process are "Cyclamate Sodium Level Analysis" and "Soft Drinks". Based on 23 journals with 12 main journals thoroughly reviewed, it is known that there are several methods for determining sodium cyclamate levels in soft drinks, namely Alkalimetry, Gravimetry, UV-Vis spectrophotometer, and High-Performance Liquid Chromatography (HPLC). The best method for analyzing sodium cyclamate levels in soft drinks is KCKT because the KCKT method has high sensitivity and specificity and is very applicable to be used in various fields, one of which is the food industry.

Review Article: Body lotion Dari Berbagai Ekstrak Tanaman Nia Yuniarsih; Ainun Mar’atus Putri Warsito; Dinda Dinanti; Elista Indah Susanti; Mentari Mentari; Muhammad Zein Latif; Refriyanti Irma; Rifah Alena Rades
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Body lotion is an emulsion cosmetic preparation consisting of two liquids that do not mix with each other. Its function is to care for the body, both to protect and dehydrate the skin due to environmental influences. The mechanism of action of body lotion is to attract water in the air which enters the dehydrated stratum corneum due to the evaporation of water from the skin so that from this process the skin can be moisturized again. The method used in this research is to search databases taken from various scientific articles through PubMed, Science Direct, and Google Scholar. The results of this research show that from the various data obtained the result is that body lotion can be made from various plant extracts because plants have a lot of chemical compounds that are useful as antioxidants, vitamin C and others

Literatur Review : Metode Analisis Identifikasi Kualitatif dan Kuantitatif Morfin Dalam Sampel Urine Nina Elyyana; Sepvia Putri Sukma Wibowo; Tiara Nurayuni; Marsah Rahmawati Utami; Lina Nurfadhila
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Opioids are one type of narcotics that are depressant, function to reduce the functional activity of the body. Morphine is one of the classes of strong opioids that functions as a strong analgesic that is usually used in patients with severe pain such as postoperatively. Morphine has additive properties and can cause toxic effects, so it is necessary to analyze morphine in the sample. Morphine analysis is performed using biological samples such as urine. This study aims to provide an explanation of various methods in the analysis of morphine substances in urine samples both qualitatively and quantitatively. The method used in writing this scientific paper is in the form of a literature study conducted by collecting relevant journals in the period of February-June 2023. The databases used are Google Scholar and Pubmed. Based on the results of the journal review, morphine identification in biological urine samples can be done quantitatively and qualitatively by several methods, namely Rapid Diagnostic Test, Card Test, KLT, LC-MS, GC-MS, SPRi, CFIA, Spectrophotodensitometry, MS and HPLC. Methods can be adapted to each need and condition.

Efektivitas Minyak Jintan Hitam (Nigella Savita Linn) Terhadap Bakteri Staphylococcus epidermidis yang Terdapat Pada Ulkus Diabetik Indah Armaya Ningrum; Rena Meutia
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia (increased blood sugar levels) that occurs due to defects in insulin secretion, insulin action, or both. Black cumin oil (Nigella Savita Linn) is a species in the genus Nigella, which includes about 14 species of plants that contain oily solids, namely unsaturated fatty acids, arachidic acids and eicosadienoic acids, proteins, alkaloids, saponins, essential oil. The aim of this study was to determine the antibiotic activity of black cumin oil (Nigella Savita Linn) on Staphylococcus epidermidis bacteria and to determine the concentration of black cumin oil (Nigella Savita Linn) which can inhibit the growth of Staphylococcus epidermidis bacteria. The results obtained at concentrations with concentrations of 1 mg/mL, 0.75%, 0.5%, and 0.25% have an antibiotic effect on the growth of Staphylococcus epidermidis bacteria found in diabetic ulcers. The differences in the antibiotic effects of black cumin extract (Nigella Savita linn), namely concentrations of 1%, 0.75%, 0.5%, and 0.25%, have significant differences in inhibition so that it can be concluded that black cumin oil (Nigella sativa linn), significantly statistically significant (p and <0.05) inhibited the growth of Staphylococcus cholermidis in diabetic ulcers. The higher the concentration of black seed oil (Nigella sativa) the greater the inhibition zone formation.

Review Artikel: Formulasi Lipstik Dengan Menggunakan Bahan Alam Sebagai Pewarna Alami Nia Yuniarsih; Amelia Putriana; Dyah Kharisma Ariyanti; Ina Nurunnisa; Muhammad Gilang; Sahrul Setiawan; Tasya Putri; Tia Laelasari
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Lipstick is a cosmetic product used to color lips, giving an artistic effect on the face that can enhance the aesthetics of facial make-up. Besides being able to provide attractive colors, this lipstick must also contain dyes that are safe to use. As a natural ingredient in making lipstick, various natural ingredients can be used in the form of extracts such as leaves, flowers, fruit and others. The method used in this study consisted of database searches through Pubmed, Science Direct and Google Scholar for various scientific articles published between 2013 and 2023. And the purpose of this study was to determine the composition of lipsticks that use natural ingredients as natural dyes. Literature search results that meet these criteria yield up to 20 references. Based on a review of various scientific literature, extracts from natural ingredients can act as natural dyes.

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Salman

Contact Email salman.kimia@gmail.com

Phone +6285277011177

Journal Mail Official admin@journal-jps.com

Editorial Address Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123

Location Kota medan, Sumatera utara INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Salman

Contact Email
salman.kimia@gmail.com

Phone
+6285277011177

Journal Mail Official
admin@journal-jps.com

Editorial Address
Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123

Location
Kota medan,

Sumatera utara

INDONESIA