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Journal of Pharmaceutical and Sciences.

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Published by Universitas Tjut Nyak Dhien

ISSN : - EISSN : 26563088 DOI : https://doi.org/10.36490/journal-jps.com

Core Subject : Health, Science, Agriculture, Engineering,

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, Medicinal Chemistry, Molecular Pharmacology, Novel drug delivery system, Nanotechnology, Analytical Chemistry, Organic Chemistry, Natural Chemistry, Polymer Sciences, Clinical Pharmacy, pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, government policies related to pharmacy, pharmaceutical care, Medical Biotechnology, Biochemistry, food chemistry, health and applied sciences relevant to the field of pharmacy. Journal of Pharmaceutical and Sciences (JPS) accepts manuscripts in Indonesian Language (Bahasa Indonesia) with titles and abstracts in bilingual, both Indonesian and English. We accept article manuscripts in the form of original research, literature reviews, and systematic reviews. We do not accept articles in the form of case reports

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)

Articles 555 Documents

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KAJIAN KINETIKA PENENTUAN LAJU REAKSI PENETAPAN KADAR VITAMIN C PADA BROKOLI (Brassica oleracea L) DENGAN METODE TITRASI TITRIMETRI Ika Julianti Tambunan; Sulasmi Sulasmi; Siti Muliani Julianty
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Background: The damage to broccoli is caused by several factors, namely mechanical and biological. The value of freshness in broccoli can be seen from the rate of respiration, which will affect on weight loss, texture, moisture content, color changes, vitamin C content or increased physiological and microbiological activity. Methods of studying the kinetics of vitamin C oxidation reaction can be carried out through literature values, distribution turnover, distribution abuse tests, consumer complaints, and accelerated shelf-life testing. The objective of the research was to determine the effect of vitamin C levels on the reaction rate equation in terms of expired date. Objective: To determine the effect of vitamin C levels on the reaction rate equation in terms of the expiry date. Methods: This study uses a cross-sectional method, namely making observations by collecting data that has been going on and reviewing the results of research that has been going on. Results: showed that broccoli at room temperature storage had the highest vitamin C content, namely 7,216 mg, at 10C ± 2ºC broccoli contained vitamin C levels of 5.045 mg, at 5Cº ± 2ºC broccoli contained vitamin C levels of 4.283 mg and at temperature 0Cº ± 2ºC broccoli contains vitamin C levels of 4.713 mg. Conclusion: The conclusion of this study is that there is a relationship between vitamin C levels and the reaction rate equation in terms of expired date, from the results of the study it was found that there were changes in the reaction rate in the zero order, first order and second order based on storage temperature, the order that most affected the reaction rate equation was in zero order because the value of zero order r2 is close to 1

Identifikasi Cemaran Escherichia Coli Pada Makanan Jajanan yang Dijual di Kampus Universitas Abdurrab Asiska Permata Dewi; Reza Irma
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Snack food is the food processed and sold as ready-to-eat food. The snack food presented must notice sanitation and hygiene so that the food quality remains. This research aimed to identify the contamination of Eschericia Coli bacteria on snack food sold at Abdurrab University Campus. Eschericia Coli bacteria was used as an indicator of microbiological contamination on food. E. coli bacteria was non-pathogenic when it is in the digestive system and becoming pathogenic when it is outside the digestive sistem. The method used was culture method or bacteria breeding in enrichment media (Brain Hearth Infosion Broth), gram coloring, testing on selective media (Eosin Metilen Blue Agar) and test of biochemical reaction (Sulfur Indol Motility Media, Voges Pakauser, Metyl Red, Simon Citrat). The testing result on BHI broth media, 5 to 10 positive samples containing bacteria continued by gram coloring test. In the gram coloring pink color was formed which indicated that the sample contained negative gram bacteria. The test on selective media and biochemical reaction did not show the traits of Eschericia coli bacteria. Thereby, 10 types of snack food tested were not contaminated by Eschericia coli bacteria.

REVIEW : TINGKAT EFEKTIVITAS IMUNISASI CAMPAK DAN FAKTOR-FAKTOR YANG MEMPENGARUHI KEJADIAN CAMPAK DI INDONESIA Faizal Auladi Rivianto; Indah Laily Hilmi; Salman Salman
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Measles is a disease caused by Morbillivirus measles virus which is an RNA virus from the Paramyxovirus group. This disease attacks the respiratory and immune systems of a person and is contagious. Measles is easy to recognize because it has characteristic clinical symptoms and has become a universal disease. This makes measles a concern of various countries because the disease can cause death if not treated and prevented from spreading. The purpose of this study is to analyze the factors that can influence the incidence of measles in Indonesia by using a literature study in the last 6 years (2016-2022). The method used is a literature review which includes the literature search process, exclusion inclusion criteria and study selection and literature quality assessment. The total literature used is 14 samples of research articles. The results showed that there were various factors that influenced the incidence of measles, but the dominant factors influencing the level of knowledge of parents regarding measles immunization and measles immunization status. It is hoped that the public will gain insight regarding measles immunization and understand how to prevent measles and maintain a clean environment so that it does not become a breeding ground for disease

FORMULASI PELEMBAB BIBIR ALAMI DARI SARI BUAH JERUK KALAMANSI (Citrofortunella microcarpa) DAN EKSTRAK BUNGA ROSELLA (Hibiscus sabdariffa) Dwi Dominica; Delia Komala Sari; Dian Handayani; Dinda Zulkarnain; Anggi Triphosa Simanjuntak; Dinah Khairunisah; Fahma Shufyani
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Background : Exposure to UV rays from the sun can damage the lip keratin cells which protect the lips. The cosmetic used to moisturize the lips is lip balm. One of the natural ingredients that contain high antioxidants are Kalamansi oranges and rosella flowers. This study aims to make Lip Balm preparations with a concentration of F1 4% of calamansi orange juice, F2 with a concentration of 5% of rosella flower extract, F3 with a combination of calamansi orange juice and rosella flower extract. Flower extraction was obtained by maceration using ethanol. The experimental method was used in this study, and the physical stability of the lip balm was carried out for approximately 4 weeks. The results of testing the physical properties of the calamansi citrus juice and rosella flower extract have a homogeneous composition, have a pH range of 6.0-6.3, have a melting point of 51-54 ℃, and are stable in storage for 28 days, that is, there is no change on texture, aroma, taste, and color. Has a percent increase in lip moisture F0, F1, F2, and F3 respectively, namely 48.5%, 59.1%, 130.7%, and 136.4%. In this study, continued with the analysis using SPSS version 24, the value of p <0.05 was obtained at 84 hours. The conclusion is that calamansi orange juice and rosella flower extract can be formulated in the manufacture of lip balm with various concentrations.

REVIEW : POTENSI PENGGUNAAN BAHAN ALAM SEBAGAI TERAPI KOMPLEMENTER ALTERNATIF PADA PENDERITA DEMAM BERDARAH DENGUE (DBD) Fitri Aida; Salman Salman; Indah Laily Hilmi
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

DHF (Dengue Hemorrhagic Fever) is a disease that frequently occurs in tropical and subtropical climates. This disease is caused by infection with dengue virus (DENV) through the bite of the Aedes aegypty or Aedes albopictus mosquito as the primary vector. The death rate for DHF cases in Indonesia since January 2022 has increased by 89 cases compared to 2020. The main factors causing death in DHF cases are platelet deficiency and plasma leakage, which are not immediately treated. The main principle in managing DHF (Dengue Hemorrhagic Fever) is symptomatic therapy and supportive therapy, such as raising the platelet count. This study aimed to find various natural ingredients that have the potential as complementary therapies in patients with dengue hemorrhagic fever (DHF). The method used was a literature review. The results obtained were red dragon fruit skin (Hylocereus polyrhizus), sweet potato leaves (Ipomoea batatas. L), god leaves (Gynura pseudochina (L), black turmeric rhizome (Curcuma aeruginosa Roxb.), horsetail fern leaves (Equisetum hyemale), date fruit (Phoenix dactylifera), bark of Chinese castor oil (Jatropha multifida), papaya leaves (Carica papaya L), patikan kebo leaves (Euphorbia hirta), guava leaves (Psidium guajava), Wegio nutmeg (Myristica fatua) , and Sambiloto leaves (Andrographis paniculate) have the potential as a complementary therapy in DHF patients

UJI AKTIVITAS KRIM ANTI JERAWAT EKSTRAK ETANOL DAUN SEROJA (Nelumbo nucifera G.) TERHADAP BAKTERI Propionibacterium acnes DAN Staphylococcus aureus Khairani Fitri; Tetty Noverita Khairani; Muhammad Andry; Nidia Rizka; Muhammad Amin Nasution
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Background; Lotus leaves (Nelumbo nucifera G.) is one of the plants that are potentially in the field of treatment, like antibacterial antiacne. Lotus leaves contain alkaloids, saponins, tannins, flavonoids and steroids are compounds of secondary metabolites in plants that are effective as an antibacterial. Objective; The study aimed to determine the antibacterial activity of lotus leaves ethanol extract against bacteria of Propionibacterium acnes and Staphylococcus aureus. Method; The ethanol extract of lotus leaves was made by maceration method using 96% ethanol as a solvent. The in-vitro antibacterial activity test used the well method with a concentration of 10%, 20% and 30%. Results; The results of the study with concentration of 10%, 20% and 30% have the inhibition zone on the bacteria Propionibacterium acnes where the concentration of 10% of 8.7mm, a concentration of 20% of 12.4mm and a concentration of 30% by 14.5mm. And the zone of inhibition on Staphylococcus aureus bacteria has a 10% concentration of 8.1mm, the concentration of 20% of 11.1mm and a concentration of 30% of 14.1mm. Concentration is the cream of the ethanol extract of the leaves of lotus at a concentration of 30%. Conclusion; The conclusion of this study showed that the ethanol extract of lotus leaves could be formulated in a cream dosage form and has antibacterial activity against Propionibacterium acnes and Staphylococcus aureus bacteria. It is suggested to the next researchers to do fractionation to get better dosage results.

Review Artikel: Hubungan Antara Tingkat Pengetahuan terhadap Perilaku Penggunaan Antibiotik Secara Rasional pada Masyarakat Shafa Qotrunnada Widyatamaka; Indah Laily Hilmi; Salman Salman
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Antibiotics are a class of drugs that have a role in treating infections caused by bacteria. Inaccurate use of antibiotics can result in antibiotic resistance. A good level of knowledge will affect behavior so that the actions taken are more directed. This study aimed to determine the relationship between the level of knowledge on the behavior of using antibiotics in society. This study uses a systematic literature review method by selecting 11 interrelated journals and discussing the same topic. The results obtained are the knowledge of the behavior of using antibiotics in the community with a relationship. The community needs to increase knowledge about the use of antibiotics to optimize antibiotic use behavior, know the side effects, dosage, use and how to store antibiotics themselves and reduce the occurrence of antibiotic resistance in the community.

Penggunaan Bahan Alam Sebagai Terapi Pereda Nyeri Dysminorrhea Pada Remaja : Review Artikel Shipa Paujiah; Salman Salman; Indah Laily Hilmi
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Dysmenorrhea is a monthly problem for women because it can interfere with activities. Dysmenorrhea is a condition of cramping pain in the lower abdomen accompanied by other symptoms, such as headaches, nausea, et cetera, that occur 24 hours before menstruation and can last 24-36 hours. The prevalence of dysmenorrhea in Indonesia is 64,25%, with 54,89% as primary dysmenorrhea and 9,36% as secondary dysmenorrhea. Management of dysmenorrhea can be done with pharmacological and non-pharmacological. Therapy pharmacological can use NSAIDs, hormonal drugs, and pain medications. At the same time, therapy with non-pharmacological can use warm water, exercise, and natural materials as complementary therapy for dysmenorrhea pain relief therapy in a teenager. The goal is to determine what natural materials can be used for dysmenorrhea pain relief in teenagers by analyzing the frequency of pain degrees before and after being given natural materials. A methodological literature review of using natural materials as a complementary therapy for pain relief in a teenager with dysmenorrhea. The result is a change in the frequency of pain in each natural material given to teenagers. The conclusion is that temulawak, butterfly pea, soybean, tamarind, turmeric, ginger, carrot, pineapple, honey, coconut, and white turmeric extract have the potential as a complementary therapy for dysmenorrhea pain relief.

Pengaruh Konsumsi Minuman Jahe (Zingibers officinale) Saat Dismenore Pada Kalangan Remaja Angel Novia Fransiska; Indah Laily Hilmi; Salman Salman
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Ginger is a bioactive compound that has shogaol and gingerol compounds. Ginger has the activity inhibiting the enzymes cyclooxygenase and lipoxygenase from hormones. The effect of consuming ginger drinks is speedy, helping for 2-3 days after mass dysmenorrhea occurs; the relief of dysmenorrhea and giving ginger drinks is more effective for 72 hours. Dysmenorrhea is a symptom during menstruation that significantly interferes with daily activities. Dysmenorrhea can occur due to excessive hormone formation, which can cause faster contractions resulting in the narrowing of the blood lumen. Dysmenorrhea occurs from teenagers to adults. The aim of the effect of ginger drinks on dysmenorrhea is to provide adolescents with information on production health problems and the effects of consuming herbal drinks when dysmenorrhea occurs. Adolescents are the mass where puberty is from youth to adulthood. Adolescent mass often occurs from physical, psychological, and social changes. All adolescent changes are in the form of mind to the process of growing up to be productive with the first menstruation. I know the effect of ginger consumption during dysmenorrhea among adolescents by collecting several published journals from Google Scholar sources.

Review Artikel : Analisis Pengaruh Kepatuhan Dalam Mengonsumsi Tablet Fe Pada Ibu Hamil Christina Febiola Lubis; Indah Laily Hilmi; Salman Salman
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Anemia in pregnant women is a condition of iron deficiency in the blood during pregnancy. The adverse effects of anemia in pregnant women on the fetus are stunted fetal growth, premature birth, babies with congenital defects, low birth weight (LBW), and fetal death in the womb. Meanwhile, the impact of anemia on pregnant women is difficulty breathing, fatigue, fast heartbeat, high blood pressure, insomnia, and an increased risk of bleeding. This research was conducted using a literature review study method. Data search was carried out using internet searches with references that match the criteria that will be used as a source for further research. To reduce the rate of anemia in pregnant women and reduce the adverse effects on mothers and babies due to anemia, this can be overcome by dutifully consuming Fe tablets. Compliance of pregnant women in consuming Fe tablets in dosage accuracy, method accuracy, and frequency accuracy. Consuming iron tablets will not reduce anemia if adherence to the consumption of Fe tablets is still low. Consuming Fe tablet supplementation based on the right time and method can increase the amount of haemoglobin.

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Home Page

OAI Link

Editorial Team

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Contact Name Salman

Contact Email salman.kimia@gmail.com

Phone +6285277011177

Journal Mail Official admin@journal-jps.com

Editorial Address Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123

Location Kota medan, Sumatera utara INDONESIA

Abstract

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Contact Name
Salman

Contact Email
salman.kimia@gmail.com

Phone
+6285277011177

Journal Mail Official
admin@journal-jps.com

Editorial Address
Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123

Location
Kota medan,

Sumatera utara

INDONESIA