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INDONESIA
SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN
Published by Universitas Islam Sultan Agung
ISSN : 20851545     EISSN : 2339093X     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Sains Medika is journal of medicine and health, is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from Biomedical Sciences, Public Health, Clinical Sciences, and Medical Education to integrate researches in all aspects of human health. This journal publishes original articles, reviews article, and also interesting case reports.
Arjuna Subject : -
Articles 7 Documents
 1 
Search results for , issue "Vol 14, No 1 (2023): June 2023" : 7 Documents clear
Disaster Prone Areas and Stunting Prevalence in Indonesia: Ecological Study of 34 Provinces Lestari, Endah Febri; Sudaryo, Mondastri Korib
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 14, No 1 (2023): June 2023
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v14i1.30466

Abstract

Indonesia has a high intensity of disaster events. The prevalence of under-five stunting in Indonesia is also high. One of the targets of the Ministry of Health's Medium-Term Development Plan for 2020-2024 is to reduce stunting in children by 14% in 2024. This study aims to look at the relationship between disaster risk and the prevalence of stunting in 34 provinces in Indonesia. The study design is an ecological study approach sourced from the 2021 Indonesian Disaster Risk Index (IRBI), the 2021 Indonesian Nutritional Status Survey (SSGI), the 2018 Basic Health Research and the 2021 National Socioeconomic Survey (Susenas). This study conducted a spatial analysis, scatter plots, pearson correlation test and multivariable linear regression. From the results, it found that the higher risk of disaster increased the tendency for the prevalence of under-five stunting. It was concluded that disaster risk has a positive relationship with the prevalence of under-five stunting in Indonesia. We suggest that a disaster management program can be considered to reduce stunting in Indonesia.
Case Study: Disseminated intravascular coagulation at autopsy of a child with severe burns resulting in death Arrozhi, Muhammad Yusuf; Suriyanto, Rusyad Adi; Widagdo, Hendro
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 14, No 1 (2023): June 2023
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v14i1.30098

Abstract

Childhood is a time of growth and development, both intellectually and emotionally. The Indonesian Child Protection Commission has observed a growing number of cases of violence against children, including physical and verbal abuse, which require special attention and handling. Physical violence can include burns, which are particularly dangerous in developing countries, where the mortality rate is high. Severe burns can result in inhalation injury and sepsis, which can cause coagulation disorders, making it easier for Disseminated Intravascular Coagulation (DIC) to occur. This study aims to describe the coagulation function of severely burnt patients, investigate the potential causes of DIC, and examine other clinical data. The study used a case study approach, analyzing the corpse of a child who suffered from severe burns. An autopsy was performed and supporting examinations were conducted to determine the cause of death. The examination of the patient's laboratory results, treatment records, corpse, and anatomical pathology revealed the presence of DIC. The autopsy of the child's corpse showed severe burns, pale coloring in the tissues under the nails, and blood clots in the epidural, left ventricle, right ventricle, and veins. The cause of death was determined to be severe burns causing multiple organ dysfunction.
Potential therapy of umbilical cord mesenchymal stem cells (UC-MSC) in renal fibrosis Lusiana, Evi; Legiran, Legiran
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 14, No 1 (2023): June 2023
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v14i1.22458

Abstract

Renal fibrosis (RF) is a severe kidney pathology defined by myofibroblast anomalies that create extracellular material on the interstitial and glomerular surfaces. The current therapy for treating renal disease has not achieved excellent results. A new theory about applying umbilical cord mesenchymal stem cells (UC-MSC) to treat renal fibrosis and other fibrosis-affected organs has been developed. This review aims to elucidate the role of UC-MSC in the therapy of renal fibrosis and summarize the numerous biological mechanisms involved. A search was undertaken using PubMed and Google Scholar from 2003 to 2021 to gather information regarding the Potential therapy with UC-MSC in renal fibrosis. Multiple studies on rat models of renal fibrosis have demonstrated a considerable improvement in fibrotic kidneys following UC-MSC treatment. It can transfer functional proteins and genetic information to recipient cells that suppress the fibrosis process. UC-MSC is considered a superior approach to MSC for therapeutic purposes due to its straightforward collection, minimum immunogenicity, and solid paracrine potency. The UC-MSC cellular treatment for renal impairment is a feasible option in the future.
Drug utilization of corticosteroid in post-operative cataract patients at Klinik Mata Utama (KMU) Madura Solihah, Riyadatus; Rahmadani, Rizal Umar; Puspitasari, Dianita Rahayu
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 14, No 1 (2023): June 2023
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v14i1.28054

Abstract

A cataract is contributed to 51% of blindness in the world. Cataract surgery is needed to restore the normal eye function. Therapeutic management post cataract operative is generally carried out 1-4 weeks by administering antibiotics, corticosteroids or NSAIDs by oral or topical routes. Corticosteroids administration increase intraocular pressure (IOP), therefore should be taken into account in post-operative cataract. The aim of this study was to observe the pattern of corticosteroid use in post-cataract surgery patients at the Klinik Mata Utama (KMU) Madura. Observational retrospective research involved 153 patients who consumed corticosteroids during their post operative cataract period. The results showed that 122 patients (79.7%) received combination therapy of topical dexamethasone and oral methylprednisolone, while 31 (20.3%) received combination therapy of topical dexamethasone and oral prednisone. 140 Patients (91,6%) showed good recovery with corticosteroids, and 13 patients (8,4%) experienced the IOP as a side effect of topical corticosteroids. In conclusion, the corticosteroids therapy for post-operative cataract patients should be managed properly to prevent the side effects of increasing IOP.
Factors influencing infections caused by Extended Spectrum Beta Lactamase (ESBL) producing bacteria in patients with urinary tract infections at RSUD dr. R. Soetijono Blora Endrawati, Endrawati; Sutiningsih, Dwi; SA, Mateus
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 14, No 1 (2023): June 2023
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v14i1.31066

Abstract

Urinary tract infection (UTI) is a bacterial infection that is often found in pediatric patients. The prevalence of infections due to ESBL-producing Enterobacterales is increasing worldwide. This study aims to identify and analyze the factors that influence Extended Spectrum Beta Lactamase (ESBL) producing bacteria in UTI patients at RSUD dr. R. Soetijono Blora. A cross-sectional study has been carried out at RSUD dr. R. Soetijono Blora in January-March 2023. The results of this study showed that 58 respondents with urine culture results found Enterobacterales pathogenic bacteria. Based on the sensitivity test for the Extended Spectrum Beta Lactamase (ESBL) enzyme producer, 39 people (67.2%) were categorized as ESBLs and 19 people (32.8%) Non-ESBLs. The study variables included age, gender, history of catheter insertion, history of stones or urinary tract surgery and history of taking antibiotics in the last 6 months. The chi-square test to determine the relationship between variables was used to determine significant risk factors. Bivariate logistic regression showed that history of catheter insertion and history of use of antibiotics in the last 6 months were significant risk factors. Prevalence of UTIs due to ESBL-producing Enterobacterales in RSUD dr. R. Soetijono Blora is high and the wise use of antibiotics, especially the third generation cephalosporins as therapy, is needed for preventive strategies to reduce antibiotic resistance
Effect of nasal irrigation on eosinophil and recurrence in allergic rhinitis Sulistyanto, Agung; Wardani, Andriana Tjitria Widi; Maharani, Virgi Mayang
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 14, No 1 (2023): June 2023
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v14i1.31474

Abstract

Until now, the treatment of allergic rhinitis has not been satisfactory. Patients with allergic rhinitis are highly dependent on medical pharmacological treatment. Nasal irrigation is expected to help reduce symptoms due to decreased eosinophil counts and recurrence of allergic rhinitis. This study aims to determine the effect of nasal irrigation on eosinophils and the recurrence of allergic rhinitis—experimental research by pre – post-test group design. Twenty samples of allergic rhinitis patients were trained to wash their nose once a day at home—nasal mucosal secretion was collected to count eosinophils before and after intervention. The degree of recurrence was assessed based on the symptoms of nasal congestion, runny nose, sneezing, and itchy nose. The degree is divided into three groups: decrease, remain, and increase. The statistical analysis used in this study for bivariate analysis was Wilcoxon Test. There was a significant decrease in eosinophil count (p = 0.00) and recurrence of nasal congestion (p = 0.00), runny nose (p = 0.00), sneezing (p = 0.001) and itchy nose (p = 0.00) in allergic rhinitis after nasal irrigation intervention. Nasal irrigation treatment can help decrease eosinophil count and recurrence of allergic rhinitis.
Effect of triamcinolone acetonide injection on pterygium recurrence in postoperative subconjunctival patients Bellarinatasari, Nika
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 14, No 1 (2023): June 2023
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v14i1.2202

Abstract

Pterygium is an eye disorder characterized by fibrovascular tissue from the bulbar conjunctiva encroaching on the cornea. Inflammation has been suggested to play a role in the pathogenesis of pterygium, indicated by elevated levels of anti-inflammatory cells and markers. Triamcinolone acetonide is a steroid commonly used to treat eye diseases. This study evaluated the effects of anti-inflammatory triamcinolone acetonide injection after the pterygium surgery. This study included 71 eyes of 71 patients. The patients were divided into two groups: triamcinolone and control group. Each eye received a subconjunctival triamcinolone injection of 2.5 mg/ 0.1 ml or no after pterygium surgery with bare sclera technique. The infusion was done around the excision area. Before and after the surgery, the ocular pressure was evaluated. Topical steroid antibiotics and oral analgesics were administrated. The outcomes were assessed one day, week, three weeks, and one month after surgery under slit-lamp examination and noncontact tonometry. The evaluated outcomes were the presence of fibrovascular tissue and intraocular pressure. This study was done by a surgeon and assisted by a nurse. There are 71 eyes in this study; 10 eyes are lost during follow-up. The 61 eyes were divided into 28 triamcinolone and 33 control group. The recurrence of pterygium was found in 2 (39. 3%) of the triamcinolone group and in (10.7%) of the control group (p=0.16). Eight eyes showed increased ocular pressure, and one patient developed granuloma. Subconjunctival triamcinolone injection after pterygium surgery did not significantly reduce pterygium recurrence.

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