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INDONESIA
SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN
Published by Universitas Islam Sultan Agung
ISSN : 20851545     EISSN : 2339093X     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Sains Medika is journal of medicine and health, is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from Biomedical Sciences, Public Health, Clinical Sciences, and Medical Education to integrate researches in all aspects of human health. This journal publishes original articles, reviews article, and also interesting case reports.
Arjuna Subject : -
Articles 7 Documents
 1 
Search results for , issue "Vol 15, No 1 (2024): June 2024" : 7 Documents clear
Management of restrictive and obstructive lung disease in intensive care unit: a review Listiarini, Dian Ayu; Jufan, Akhmad Yun; Wisudarti, Calcarina Fitriani Retno
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2024): June 2024
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v15i1.35660

Abstract

Lung disease is broadly divided into obstructive lung disease (OLD) and restrictive lung disease (RLD). The latter is a disorder of the parenchyma, pleura, thorax, or neuromuscular walls of the lungs, characterized by decreased total lung capacity due to reduced lung distensibility. Meanwhile, OLD causes increased resistance to flow due to the blockage of part or all of the respiratory tract from the trachea to the terminal bronchioles. These two diseases' initial symptoms and signs are common, such as shortness of breath, coughing, cyanosis, respiratory muscle retractions, snoring, and fever. Early detection is needed to recognize differences in symptoms and signs, establish a diagnosis, and carry out appropriate treatment. It is essential to differentiate between RLD and OLD because they have different therapeutic management. This review aims to discuss the management of restrictive and obstructive lung disease in intensive care unit It is drawn upon various sources, including case reports, literature reviews, systematic reviews, and meta-analyses, to provide an overview of the difference between RLD and OLD to help clinicians differentiate between RLD and OLD and provide appropriate therapeutic management. Although RLD and OLD have similar signs and symptoms, they have different pathologic processes. The leading cause of RLD is a pathological condition that causes a decrease in lung compliance. Meanwhile, the primary pathological process of OLD is an increase in airway resistance, which causes typical obstructive symptoms. Addressing this area of interest can help clinicians to provide appropriate management of both pharmacotherapy and mechanical ventilation and monitoring of respiratory mechanisms
Corneal edema after cataract surgery in diabetic and non-diabetic patients Indrajati, Christina; Rahmawati, Atik; Mahardika, Nabila Ayu
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2024): June 2024
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v15i1.34177

Abstract

Patients with diabetes mellitus undergoing phacoemulsification cataract surgery face an elevated risk of corneal edema, primarily due to metabolic disturbances that impair endothelial cell function, leading to delayed post-operative recovery. This prospective cohort study aimed to examine the relationship between diabetes mellitus and the incidence of corneal edema following phacoemulsification. A total of 180 cataract patients scheduled for surgery at Sultan Agung Eye Center, Semarang, and Dr. R. Soedjati Soemodiardjo Regional Public Hospital, Purwodadi, Indonesia, between July and August 2023, were enrolled. Participants were divided into two groups based on the presence or absence of diabetes mellitus. Corneal edema and visual acuity were evaluated on post-operative days 1 and 7. Statistical analyses assessed the association between diabetes mellitus and post-operative corneal edema, with a significance threshold set at p < 0.05. The results indicated that pre-operative visual impairment was significantly worse in non-diabetic patients compared to diabetic patients (p = 0.000). However, post-operative visual improvement was significantly greater in non-diabetic patients on both day 1 (p = 0.02) and day 7 (p = 0.00) compared to diabetic patients. Additionally, the incidence of corneal edema was significantly higher among diabetic patients on both day 1 (p = 0.004) and day 7 (p = 0.001) post-surgery. These findings suggest that diabetes mellitus is associated with a higher risk of corneal edema and delayed visual recovery following phacoemulsification cataract surgery.
Knowledge, religiosity, and decision to use Sharia hospital services among residents in Central Java, Indonesia Wilda, Amelia; Putri, Sabrina Mutiara; Vinalisa, Bintang Ananda Afrilianti; Salsabila, Reefa Dyah; Nafisatussalimah, Putri Sirry; Santoso, Arifin; Sulistyaningrum, Indriyati Hadi
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2024): June 2024
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v15i1.33510

Abstract

The increasing tendency of society to apply Sharia principles in all aspects of life today is supported by the presence of Sharia hospitals that integrate Sharia values in administration, healthcare services, and patient care standards as regulated in the fatwa of the National Sharia Council (Dewan Syariah Nasional) No. 107/DSN-MUI/X/2016. Knowledge refers to everything known by an individual that can affect behavior. Meanwhile, religiosity is an individual's level of religious commitment that reflects the extent of belief in the values and expectations of the religion they adhere to or practice; in this study, it is the Muslim community. This research aims to examine the effect of the community's knowledge about Sharia hospitals and the religiosity of the Central Java community on their decision to seek medical treatment at Sharia hospitals. The research method used in this study was analytical observational with a cross-sectional study approach. Data was collected through direct questionnaires from the Central Java community using the snowball sampling technique. The research results indicate that knowledge and religiosity, both partially and simultaneously, affect the decision of the Central Java community to choose Sharia hospitals for medical treatment, with a p-value of 0,000. Partially, it is found that knowledge has an effect of 10,2%, while religiosity has an effect of 23% on the community's decision to seek medical treatment at Sharia hospitals. The conclusion of this study suggests that knowledge and religiosity significantly impact the Central Java community's decision to opt for Sharia hospitals for medical treatment.
Ovarian cyst mimicking acute appendicitis in children: a case report Noor, Hafni Zuchra; Wahyuni, Alfaina; Retnowati, Sulistiari
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2024): June 2024
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v15i1.31564

Abstract

Pediatric acute appendicitis is common; however, it is different from torsion ovarian cysts. The estimated incidence of ovarian torsion in children is 5 per 100,000 girls. Herein, we report two cases of ovarian torsion mimicking pediatric acute appendicitis mimicking ovarian cyst. In the first case, a girl who was being assessed for acute appendicitis was identified to have torsion of the ovarian cyst during the surgery. In the second case, a girl experienced a ruptured ovarian cyst but then got severe appendicitis following the surgical procedure. The simultaneous occurrence of appendicitis and ovarian cysts is rare. These two patients' acute gastrointestinal complaints and symptoms exhibit similarities and may coincide. Both patients underwent salpingo-oopherectomy and appendectomy. Both patients were healthy on hospital discharge in a healthy condition. Female patients with severe abdominal pain and amenorrhea should be evaluated for ovarian torsion. Diagnosing the condition may be challenging due to non-specific clinical signs.
Surveillance of pathogenic Leptospira among rodents and small mammals in enzootic areas of plague in Pasuruan Indonesia Febriani, Siti Amanah; Dhanti, Kurnia Ritma; Kurniawan, Kurniawan; Ristiyanto, Ristiyanto; Junaedi, Arief; Sukowati, Caecilia Hapsari Ceriapuri; Handayani, Farida Dwi
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2024): June 2024
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v15i1.37499

Abstract

Leptospirosis is a globally significant yet often overlooked zoonotic infection. Several regions in Indonesia are endemic for leptospirosis, including East Java. Pasuruan a region located in the East Java province of Indonesia, has been recognized as an enzootic area of plague infection. However, the presence of other rodent-borne diseases has not been reported. This study aims to detect the presence of pathogenic Leptospira in rats and small mammals in the enzootic plague area of Pasuruan in Indonesia. This study belongs to the type of observational analytic research with a cross-sectional study design. Simple random sampling was conducted to trap a total of 119 forms 107 rats and 12 small mammal kidneys were analyzed molecularly (PCR) to detect Leptospira bacteria with the LipL32 gene as the target. The study revealed that 7.6% (9/119) of rats in the enzootic areas of plague (Sedaeng, Tosari, Surorowo, Petren, Pakis Bincil, Kutukan) were found to carry Leptospira DNA, indicating a significant difference between infection rates per region (p < 0.0001).  Rattus tanezumi was identified as the Leptospirosis reservoir in settlements habitats with a percentage of 13.2%, Rattus tiomanicus was detected at 28.6% in forest habitats, and Rattus exulans was found at 4.4% in both habitats. The findings in our study, it is crucial for the community to increase awareness of the spread of rodent-borne diseases, including Leptospirosis.
Effect of Nigella sativa extract on nasal mucosal inflammation in rats exposed to cigarette smoke Alamanda, Fathika; Dewi, Anna Mailasari Kusuma; Marliyawati, Dwi; Santosa, Yanuar Iman
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2024): June 2024
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v15i1.22833

Abstract

Cigarette smoke contains toxic compounds that can initiate an inflammatory reaction and infiltrate inflammatory cells. The nasal mucosa is the initial part of the respiratory system that comes into contact with irritating chemicals such as cigarettes. Prior studies indicated that Nigella sativa extract (NS) has thymoquinone, a bioactive compound with anti-inflammatory properties. Our study aims to determine the effect of different doses of NS on inflammation of the nasal mucosa in Wistar rats exposed to cigarette smoke. The study employed an experimental post-test-only control group design. Twenty-five Wistar rats were randomly assigned to one of the five groups: negative control (K-), positive control (K+), and three treatment groups of P1, P2, and P3 receiving NS at the dose of 0.5, 1, and 1.5 g/kg bw/day, respectively. All treatment groups and the positive control group were exposed to smoke from 4 cigarettes/day for 28 days. The degree of inflammatory cell infiltration was evaluated using a histological scoring : 0 if normal; 1 if infiltration was less than 1/3; 2 if infiltration was between 1/2 and 2/3, 3 if infiltration of more than 2/3 indicating normal, less than 1/3, 1/3 to 2/3, and more than 2/3, respectively. The degree of inflammatory cell infiltration in group: K(-): 1.00 ±0.00, K(+): 1.00±0.00, P1: 1.00±0.00, P2: 1.00±0.37, and P3: 1.00±0.33. The Kruskal-Wallis test showed a p-value of 0.001, indicating a significant difference. The Mann-Whitney test revealed significant differences between the K+ and P2 groups (p=0.032), K+ and P3 groups (p=0.013), and P1 and P3 groups (p=0.049). In conclusion, NS can decrease the presence of inflammatory cells in the nasal mucosa in Wistar rats exposed to cigarette smoke.
Peritoneal lavage with sterile water reduces IL-1 levels and postoperative adhesions following laparotomy in rats Fernandi, Ryan; Sudartana, I Ketut; Sueta, Made Agus Dwianthara; Mahayasa, I Made; Yasa, Ketut Putu; Wibawa, I Gusti Agung Bagus Krisna
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2024): June 2024
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v15i1.36698

Abstract

Peritoneal lavage with normal saline is common in abdominal surgeries, yet recent studies indicate that it increases intraperitoneal adhesion risks. This study compares the effects of peritoneal lavage with normal saline versus sterile water on interleukin-1 (IL-1) levels and intraperitoneal adhesion following laparotomy in rats. In this post-test control group study, 20 adult Wistar rats were subjected to laparotomy before being randomly divided into two groups to receive either intraperitoneal lavage with normal saline (0.9% NaCl) or sterile water. After 7 days, IL-1 level and degree of adhesion were evaluated. The saline group had higher adhesion levels (4 rats with grade 4, 5 with grade 3, 1 with grade 2) than the sterile water group, which had lower levels (2 rats with grade 3, 5 with grade 2, 3 with grade 1). There was a significant difference in IL-1 levels between the sterile water group (37,111.6 ± 6,535.61 pg/ml) and the normal saline group (57,456.3 ± 10,583.41 pg/ml). There was a significant correlation between IL-1 levels and adhesion grade (p=0.008). Intraperitoneal lavage with sterile water results in significantly lower adhesion grade and IL-1 levels than normal saline, suggesting its potential for reducing postoperative adhesions. Further studies are needed to elucidate the mechanism of reduced adhesion and inflammation associated with sterile water lavage.

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