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JPS (Jurnal Pharma Saintika)
Published by Akademi Farmasi Dwi Farma Bukittinggi
ISSN : -     EISSN : 2580684X     DOI : 10.51225
Core Subject : Health,
Health Professions
Jurnal ini menyajikan hasil penelitian dibidang Farmasi.Jurnal ini bertujuan untuk menjembatani kesenjangan antara penelitian dan praktik, memberikan informasi, ide-ide dan pendapat, selain analisis kritis kemajuan dalam penelitian Farmasi.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 58 Documents
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OPTIMASI WAKTU EKSTRAKSI DAUN PECUT KUDA (Stachytarpheta jamaicensis) DENGAN METODE DIGESTI DAN NILAI RENDEMEN EKSTRAKNYA Amin, asni; Risda Waris; Devita
Journal Pharma Saintika Vol. 8 No. 2 (2025): Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v8i2.76

Abstract

Abstract: Extraction of natural medicines can not only extract chemical components from the sample, but also be a guideline in determining yield value (extract). One of the extraction methods is digestion. The purpose of this research is to optimize the digestion extraction time and determine the high yield value of blue porterweed (Stachytarpheta jamaecensis) leaf extract obtained. Horse whip leaf extract (EPK) was obtained by digestion at 2 (D1), 4 (D2) and 6 (D3) hours at 40oC using 70% ethanol solvent, the ethanol extract was evaporated with a rotary vaccum-evaporator 10 degrees below its boiling point to become a thick extract. Each extract was weighed and the yield value was calculated. The results of digestion extraction obtained the yield value of EPK in D1 = 12,4%; EPK in D2 =  15,36%, and EPK in D3 = 12.3%. Extraction optimization using the digestion method can be used as a reference for the development of herbal medicines for  traditional medicine manufacturers.
IDENTIFIKASI LENGKUAS (Alpinia galanga) SECARA KLT DALAM JAMU PEGAL LINU YANG BEREDAR DI KOTA PINRANG, SULAWESI SELATAN Nirmayani Abd. Kadir; Amin, asni; Mamat Pratama; A. Amaliah Dahlia
Journal Pharma Saintika Vol. 8 No. 2 (2025): Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v8i2.77

Abstract

Abstract: Jamu pegal linu (tradisional Indonesia medicine)  is one of the herbs used to treat aches and pains by the Indonesian people. The galangal  is often found in the composition of jamu pegal linu (JPL). The purpose of this study was to identify by TLC the presence of galangal  (Alpinia  galanga/AG) in JPL  from the  Pinrang city, Province of South Sulawesi. Methods:   Jamu pegal linu that included  AG  in the label was collected from jamu shops in Pinrang city. Each jamu sample was extracted with 96% ethanol for 24 hours, as well as  AG. The extracts were then evaporated until thick. Each viscous extract was analyzed  on a plat TLC (thin layer chromatography) plate with a stationary phase of silica gel GF254, and a mobile phase of n-hexan-ethyl acetate (8:2), then detected using UV lamp 254 nm and 366 nm wavelenght, and calculated the Rf (Rate of flow) value. The results showed that herbs A, B, C, D, and E were identified as containing at Rf 0,38; 0,87 dan 0,95 after detection in UV 366 nm, and AG at Rf ..... in UV 254 nm detection. The identification of these herbs can be used as a reference for producers and consumers to confirm the correctness of the composition of AG  rhizome  in jamu pegal linu.
BIOAKTIFITAS ANTIINFLAMASI EKTRAK METANOL RIMPANG SIJANGKANG (Hornstedtia scyphifera var. Fusiformis Holttum) TERHADAP TIKUS PUTIH JANTAN Mevy Trisna; Renatalia Fika; Ilza Fitri Handayani; Ainun Naim; Muhajri Agusfina
Journal Pharma Saintika Vol. 8 No. 2 (2025): Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v8i2.78

Abstract

An investigation examined the anti-inflammatory effects of the methanol extract from the Sijangkang rhizome (Hornstedtia scyphifera var. Fusiformis Holttum) on male albino rats that were induced with 1% carrageenan at a volume of 0.2 ml/rat. The tool used in this test is a Plethysmometer with a working principle using Archimedes' law. A Plethysmometer is a tool used to measure edema volume. The way it works is based on measuring the volume of fluid due to the immersion of the organ whose degree of inflammation is measured into mercury liquid. The working principle is that if an object is dipped into a liquid, the object will get an upward pressure equal to the liquid that is pushed by the object. From the results of the research that has been done, it can be concluded that the methanol extract of sijangkang rhizome has anti-inflammatory activity. The research conducted is an experimental study using 12 test animals consisting of 4 treatment groups, namely 1 negative control group (aquadest), and 3 groups of test substances methanol extract of sijangkang rhizome. The doses used were 2 mg/200 g BW/5 ml, 4 mg/200 g BW/5 ml, and 8 mg/g BW/5 ml. The negative control group and the test group with doses of 4 mg/200 g BW and 2 mg/200 g BW showed a very high and continuously increasing percentage of edema formation. This was due to the fact that the negative control group received only distilled water, while the test group was administered a small amount of the test substance that failed to prevent edema formation. In contrast, the test substance, at a dose of 8 mg/200 g body weight/5 ml, exhibited anti-inflammatory properties.
GAMBARAN PERENCANAAN OBAT DENGAN METODE ANALISIS ABC DI APOTEK ALETHEIA SEMARANG PERIODE JANUARI - DESEMBER 2024 Solichah, Ayu Ina; Anggun Ayuningtias Putri; Eleonora Maryeta Toyo
Journal Pharma Saintika Vol. 8 No. 2 (2025): Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v8i2.79

Abstract

Medication planning is a crucial component of the medication management process in pharmacies. Poor drug planning can lead to budget inefficiencies in procurement, resulting in ineffective spending and unavailability of medicines in the right quantity and at the right price. This study aims to analyze the ABC classification of medications at Aletheia Pharmacy, Semarang. A quantitative descriptive method was used by collecting and analyzing all sales data to describe how drug planning and procurement are conducted, using retrospective data and available sales documents from January to December 2024. The ABC method begins with collecting pharmacy sales data, followed by calculating the percentage contribution of each item to the total sales value. The medications are then grouped into three categories: Category A for high-value items, Category B for medium-value items, and Category C for low-value items. Planning is then carried out by prioritizing Category A medications, while Categories B and C are managed with simpler approaches. From the analysis, a total of 1,260 medication items were identified. Category A consisted of 369 items (29.3%) with an investment value of Rp. 271,123,000 (70.96%). Category B included 425 items (33.7%) with an investment value of Rp. 76,369,000 (19.99%). Category C comprised 466 items (37%) with an investment value of Rp. 34,422,100 (9.01%).
HUBUNGAN BAURAN PEMASARAN (MARKETING MIX) DENGAN OMSET APOTEK: TINJAUAN LITERATUR Meridona; Sari, Seftika; Frimayanti, Neni
Journal Pharma Saintika Vol. 9 No. 1 (2025): Oktober : Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v9i1.81

Abstract

Abstract: In recent years, the pharmaceutical and healthcare industries have undergone significant changes, marked by increasing competition among service providers, including pharmacies. Pharmacies must adapt their marketing plans in response to regulatory changes, service digitization, and increasing public health awareness. The purpose of this study is to conduct a systematic review of the existing literature on the relationship between pharmacy turnover success and marketing mix tactics. Databases including Google Scholar, PubMed, and Sciencedirect were searched, analyzing English and Indonesian-language publications published between 2015 and 2025 using the PRISMA method for systematic literature review. Of the 745 articles found, five were eligible for inclusion and further analysis. The results indicate that the key elements of the 7Ps of marketing—competitive pricing, product availability, and high-quality service involving both human resources and processes—have a significant impact on purchasing decisions and consumer loyalty. The study suggests that digital-based marketing initiatives and consumer education are important complementary elements in improving pharmacy performance. Overall, this study concludes that to maximize pharmacy turnover and competitiveness in the ever-changing healthcare environment, the 7P marketing mix must be implemented in an integrated and customer-oriented manner.
ANALISIS EFEKTIFITAS TERAPI KOMBINASI ANTIPLATELET ASPIRIN-CLOPIDOGREL DENGAN ASPIRIN-TICAGRELOR PADA PASIEN SINDROM KORONER AKUT: SYSTEMATIC LITERATURE REVIEW Anwar, Andrian Hoerul
Journal Pharma Saintika Vol. 8 No. 2 (2025): Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v8i2.84

Abstract

Acute Coronary Syndrome (ACS) is one of the leading causes of cardiovascular morbidity and mortality, making dual antiplatelet therapy (DAPT) a crucial component of treatment. The combination of aspirin-clopidogrel has long been used, but its effectiveness is limited by genetic resistance, whereas aspirin-ticagrelor offers a faster and more consistent antiplatelet effect. This study aims to analyze the effectiveness and safety of both regimens through a Systematic Literature Review (SLR) by searching PubMed, Scopus, ScienceDirect, and Cochrane Library for articles published between 2015 and 2025. The results show that aspirin-ticagrelor is more effective in reducing Major Adverse Cardiovascular Events (MACE), including myocardial infarction, stroke, and cardiovascular mortality, but is associated with a higher risk of major bleeding and dyspnea. Conversely, aspirin-clopidogrel is considered safer and more affordable, although its effectiveness is relatively moderate. Therefore, the choice of DAPT should be individualized according to thrombotic and bleeding risks as well as patients’ economic conditions, to ensure appropriate therapy particularly in developing countries such as Indonesia.
PERAN TABLET CURCUMA DALAM MENURUNKAN RISIKO HEPATOTOKSISITAS PADA PASIEN TB PARU YANG MENJALANI TERAPI OAT DI RS PASAR REBO KOTA JAKARTA TIMUR Dini Permata Sari; Nhila Putri Evani; Rangki Astiani
Journal Pharma Saintika Vol. 9 No. 1 (2025): Oktober : Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v9i1.88

Abstract

Abstract: Curcuma is known to play a role in preventing the side effects of anti-tuberculosis drugs (OAT), including hepatotoxicity, by protecting liver cells from oxidative stress and inflammation induced by drugs. The objective of this study was to determine the relationship between Curcuma tablet supplementation and the level of liver damage (hepatotoxicity), as measured by AST, ALT, and total bilirubin levels in pulmonary tuberculosis patients at Pasar Rebo Hospital. This study was non-experimental and classified as an analytical study with a cross-sectional approach. Data collection was conducted retrospectively, by reviewing past medical data and events. The sample in this study consisted of a portion of pulmonary tuberculosis patients undergoing OAT therapy at Pasar Rebo Hospital, East Jakarta, during the period of January–December 2024. The results showed that Curcuma tablet supplementation provided significant benefits to the liver health of pulmonary TB patients, as indicated by a statistically significant decrease in AST, ALT, and total bilirubin levels (p < 0.05) after treatment. This decrease in liver enzyme and bilirubin levels reflects improved hepatic function and reduced hepatotoxicity. Thus, Curcuma tablets have been proven effective as a hepatoprotective agent in the context of OAT therapy..
ANALISIS POLA DAN EFEKTIVITAS TERAPI ANTIBIOTIK EMPIRIS TERHADAP PERBAIKAN KLINIS PADA PASIEN KERATITIS BAKTERIAL RAWAT JALAN Widya Ari Sandi; Seftika Sari; Neni Frimayanti
Journal Pharma Saintika Vol. 9 No. 1 (2025): Oktober : Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v9i1.90

Abstract

Abstract. Bacterial keratitis is a corneal infection that may lead to pain, visual impairment, and even permanent blindness if not promptly and appropriately treated. In outpatient settings, empirical antibiotic therapy is often chosen as the initial management because culture and sensitivity results require more time, whereas delays in therapy may worsen the clinical condition. This study aims to evaluate the effectiveness of empirical antibiotic therapy on clinical improvement and follow-up visits in patients with bacterial keratitis. A systematic literature review was conducted by searching PubMed and Google Scholar for articles published between 2015 and 2025. From 242 articles identified, 12 met the inclusion criteria and were analyzed further. The findings revealed that moxifloxacin and ciprofloxacin were the most frequently prescribed topical antibiotics, with treatment durations ranging from 7 to 21 days. Overall, empirical therapy was shown to accelerate clinical improvement, particularly within the first week of treatment. However, evidence supporting a reduction in follow-up visit frequency remains limited and presents varied results across studies, potentially due to differences in study design and patient conditions. Factors such as treatment regimen, duration of therapy, disease severity, and patient characteristics were also reported to influence the variability in outcomes. In conclusion, empirical antibiotic therapy appears to be clinically effective for bacterial keratitis. Nevertheless, to obtain a more comprehensive understanding of its impact on follow-up visits and implications for outpatient services in Indonesia, further research with larger sample sizes and prospective study designs is required.

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