cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Marisa
Contact Email
admin@multitechpublisher.com
Phone
+6285359562521
Journal Mail Official
admin@multitechpublisher.com
Editorial Address
Jl Veteran gg Cahaya, No 103 Berastagi
Location
Kab. karo,
Sumatera utara
INDONESIA
International Journal of Applied and Scientific Research (IJASR)
Published by MULTITECH PUBLISHER
ISSN : -     EISSN : 30257670     DOI : https://doi.org/10.59890/ijasr.v2i2
Core Subject : Religion, Science, Social, Engineering,
Religion Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Decision Sciences, Operations Research & Management Social Sciences
International Journal of Applied and Scientific Research (IJASR) is a multidisciplinary peer reviewed Journal aimed to publish original research papers in all main branches of science (All scientific disciplines) with a double-blind peer reviewed refereed journal that publishes empirical, conceptual, and review papers of exceptional quality that contribute to enrich the humans life.
Arjuna Subject : Umum - Umum
Articles 106 Documents
 7   8   9   10   11 
Evaluation of the Histological Effects of Allium Cepa Administration on the Prostate Histology and Prostate Specific Antigen of Male Albino Rats Induced with Ciprofloxacin Mathew, Uwuigbe; Ohiwerei Wisdom Omogbai; Edebiri Ogbemudia E; Ajanwachukwu Ogbonna Wilson; Oriahoghen E E
International Journal of Applied and Scientific Research Vol. 2 No. 11 (2024): November 2024
Publisher : MultiTech Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The primary objective of this study is to assess the histological impact of Allium cepa administration on prostate histology and prostate-specific antigen (PSA) levels in male albino rats that were induced with ciprofloxacin. A total of 100 albino rats, each weighing between 150–250g, were used in the experiment. The experimental group was further divided into four subgroups, each containing 10 rats, labeled as Groups A, B, C, D, and E. Group A served as the control, while Group B received only ciprofloxacin. Group C was administered ciprofloxacin along with 100mg of Allium cepa extract, whereas Group D received ciprofloxacin and 200mg of Allium cepa extract. Group E was treated solely with Allium cepa extract. Groups B, C, and D were given 22.86 mg/kg of oral ciprofloxacin (500 mg/tablet), manufactured by Fidson Health Care Ltd. The ciprofloxacin was obtained from a reputable pharmaceutical store in Ekpoma, Edo State, and administered via gavage. The control group was provided with only water and food. The PSA levels in control and test subjects were recorded as Mean ± SEM. For the control group, the PSA level was 0.6250 ± 0.085 ng/ml. The PSA levels for test groups B, C, D, and E were 1.575 ± 0.417 ng/ml, 1.200 ± 0.123 ng/ml, 1.125 ± 0.048 ng/ml, and 3.300 ± 0.835 ng/ml, respectively. Notably, only Group E exhibited a significant increase (P<0.05) in PSA levels when compared to the control group.In conclusion, this study indicates that exposure to ciprofloxacin and Allium cepa at mild or moderate doses can lead to severe histopathological changes in the testis, prostate, and epididymis, with the exception of the brain
Biochemical Changes Associated with Abortion: A Review Omogbai, Ohiwerei Wisdom; Eseigbe Emmanuel Ebosetale
International Journal of Applied and Scientific Research Vol. 2 No. 12 (2024): December 2024
Publisher : MultiTech Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Abortion, whether spontaneous or medically induced, triggers a range of physiological and biochemical changes in the female body. The termination of pregnancy influences hormonal balance, metabolism, and enzymatic activity, which can affect reproductive health. This review explores the biochemical impacts of abortion, including hormonal disruptions, oxidative stress, inflammatory responses, immune system alterations, neurotransmitter imbalances, and potential long-term metabolic effects
Histomorphological and Hormonal Changes in the Testes of Albino Rats Treated with Herbal Aphrodisiac Formular Wilson, Ajanwachukwu Ogbonna; Ohiwerei Wisdom Omogbai; Olugbenga Mary; Echekwube Marylyn E; Obeagu E I
International Journal of Applied and Scientific Research Vol. 2 No. 12 (2024): December 2024
Publisher : MultiTech Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Herbal supplements, commonly referred to as botanicals, are plant-derived products utilized for their therapeutic properties. This study aims to examine the histomorphological and hormonal changes in the testes of albino rats treated with a herbal aphrodisiac formula. A total of eight male and two female rats were used in the study, with the males divided into control and test groups, while the females were used for mating with the test groups. Group A (Control) received only normal feed (growers’ mash) and distilled water daily for four weeks. Group B was administered 0.2 ml of Men’s Formula supplement and sacrificed on day 7, whereas Group C was administered 0.2 ml of Men’s Formula supplement and sacrificed on day 14. The body weights of the animals were measured before and after acclimatization, and similar weight assessments were performed at the end of each phase, with the average weights recorded accordingly. At the end of the procedure, the testes of each rat were excised under chloroform anesthesia and fixed in 10% formal saline for subsequent histological examination. Blood samples were collected via cardiac puncture into plain bottles, and sera were later separated for hormonal analysis. The results indicated that the herbal aphrodisiac formula enhanced testosterone levels and increased testis weight. However, no significant change (P > 0.05) was observed in body weight, and testicular histology remained unaffected. Further studies with prolonged usage of the herbal aphrodisiac formula are recommended to determine potential long-term effects
Assessment of the Effect of Graded Doses Alligator Pepper on Uterus of Female Albino Rats Mathew, Uwuigbe; Ohiwerei Wisdom Omogbai; Amina Momodu; Ogbe O Clementina
International Journal of Applied and Scientific Research Vol. 2 No. 12 (2024): December 2024
Publisher : MultiTech Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The aim of this study is to determine the histological effects of alligator on the uterus of wistar rats, as a result of different doses of alligator administered orally. Fifty (50) adult female wistar rats were use for this study for a period of 28 days (14 days for aclimitization and 14 days for administration). The rats were randomized and divided into five groups (A, B, C, D and E) of ten (10) animals each. the animals were sacrificed two times. All animals were sacrificed by cervical dislocation at least three hours after the last administration of alligator pepper. The results showed the weight before acclimatization, after acclimatization, before sacrifice of control and test subjects in which the Mean±SEM of weight before acclimatization, after acclimatization, before sacrifice were 247±3.00, 226±2.00 and 226±2.00 respectively for control subjects. None of the test groups were found statistically significant (p<0.05) when compared with their respective control. The micrograph result showed that ovary group A in the photomicrograph had a normal histological features. Uterus group B administered with 100mg/kg of aqueous extracts of alligator pepper showed clear carcinoma (neoplastic changes) of the endomentry uterus. Uterus group C (200mg of Alligator pepper) and group D (300mg of Alligator pepper) showed hyperplasic cells of the endomentry uterus. Uterus group E (400g of Alligator pepper) photomicrograph showed andenomyosis endoutrolysis internal. In conclusion, hyperplasic cells ( a condition suggestive of Hyperplasia) was found to be more common in groups with moderate doses. This study suggests that the oral administration of Alligator pepper at mild or moderate doses could cause severe histopathologic changes in the uterus without having any adverse effect on body weight
Histological Effect of Ultra Violet (UV) Light on the Testis of Albino Wistar Rats Uwuigbe Mathew; Ohiwerei Wisdom Omogbai; Ogbe O Clementina; Ajanwachukwu Ogbonna Wilson; Obeagu E I
International Journal of Applied and Scientific Research Vol. 2 No. 12 (2024): December 2024
Publisher : MultiTech Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

UV light, or ultraviolet light, is a type of radiation that falls between the visible light and X-ray regions of the electromagnetic spectrum. It is a form of electromagnetic radiation emitted by the sun and artificial sources, such as tanning beds and UV lamps. It has a shorter wavelength than visible light, ranging from 100 to 400 nanometers (nm). It is categorized into three types based on their wavelengths: UVA, UVB, and UVC. The aim of this study is to evaluate the histopathological effect of uv light on the testis of male Wistar albino rats. A total of fifty (50) adult Albino Wistar rats of comparable sizes were used for this study. They were divided into four equal groups (A – E) with ten (10) rats each. Group A served as the control and the rats were given distilled water and feed only. In addition to feed and water, Groups B rats were kept under Uv light for 30mins, Group C rats were kept under Uv light for 1hour twice daily, Group D rats were kept under Uv light for 2 hours thrice daily and Group E were kept under Uv light for 4 hours thrice daily. The administration was given daily for 14 days (2 weeks) and the weights of both the test and control animals was monitored before and after administration of Uv light. After the administration, the rats were put under light chloroform anaesthesia and the stomach was obtained. ANOVA was used to analyze the results of the weight and differences was considered significant at p<0.05 level of confidence. All data was expressed in table as mean ± standard deviation (SD). From the results, it was observed that Group B showed mild adenofibroma, Group C exhibited denatured testicular cells, indicating severe damage. Group D had adenocarcinoma and fatty tissue, suggesting potential malignancy and Group E presented fatty tissue. In conclusion, the exposure of testis to uv light cause significant alterations in testis histology
Sokoto Caliphate Literatures: Importance on Relieving or Remediating Drug Abuse in Northern Nigeria and Muslim Societies Tambari Abbas Bashar
International Journal of Applied and Scientific Research Vol. 2 No. 12 (2024): December 2024
Publisher : MultiTech Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Drug abuse is a menace ravaging in the modern societies. The dangers of drug abuse are plain and ubiquitous and all-pervasive. It causes effects on the body of abusers and non-users. Effects include deterioration of (physical and mental) health, school drop out, school absenteeism, crime, frauds, violence, joblessness, addiction, withdrawal effects, death, injuries, broken homes or families, and many other consequences. That is why it is pertinent to apply the lessons of Sokoto Caliphate literature in preventing drug absolutely abuse in society. The Northern Nigeria Muslims, others Muslims, and even other societies can learn greatly in Sokoto Caliphate literature to tap lessons for preventing drug abuse. The Sokoto Caliphate literature is simple, practical, relevant, and is vast. Literatures in Sokoto Caliphate are due to the jihad orchestrated by Shehu Usmanu Danfodiyo and his friends in the 19th century Hausa states. Books such as Ihya'ussunah, Nurul Albab, WasiyyatuSshaikh, Ulumul Muamalah, Udadu dai, Lubabul madkhal are vital in drug abuse prevention for preferring solutions to the menace. The solutions include methods to purify soul and mind from filthy things such as anxiety, fear, depression, sadness, frustrations. The main thing to cure these is true Iman with Allah and stepping on the status of Ihsan. In the literatures, punishment for offenders for taking drugs is outline, need for parental care, sanitizing environments (by governments) are disclosed. The other methods were fully discoursed. It is important to apply the lessons from the Sokoto Caliphate literatures to solve the prevailing drug abuse menace in the environments (societies)

Page 11 of 11 | Total Record : 106

 7   8   9   10   11 

Filter by Year

2023 2024


Reset
Filter By Issues
All Issue Vol. 2 No. 12 (2024): December 2024 Vol. 2 No. 11 (2024): November 2024 Vol. 2 No. 10 (2024): October 2024 Vol. 2 No. 9 (2024): September 2024 Vol. 2 No. 8 (2024): August 2024 Vol. 2 No. 7 (2024): July 2024 Vol. 2 No. 6 (2024): June 2024 Vol. 2 No. 5 (2024): May 2024 Vol. 2 No. 4 (2024): April 2024 Vol. 2 No. 3 (2024): March 2024 Vol. 2 No. 2 (2024): February 2024 Vol. 2 No. 1 (2024): January, 2024 Vol. 1 No. 4 (2023): December 2023 Vol. 1 No. 3 (2023): November 2023 Vol. 1 No. 2 (2023): October 2023 Vol. 1 No. 1 (2023): September 2023 More Issue