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Published by Universitas Lampung
ISSN : 23373776     EISSN : 25990527     DOI : https://doi.org/10.59042/mj.v12i1.175
Core Subject : Health, Education,
Education Health Professions Medicine & Pharmacology Public Health
Jurnal Majority dalah peer-reviewed journal yang mempublikasikan artikel-artikel ilmiah bagi mahasiswa fakultas kedokteran, dosen maupun klinisi. Jurnal Majority menerima manuskrip atau artikel dalam bidang dalam lingkup bidang kedokteran dan kesehatan. Artikel-artikel yang dipublikasikan di Jurnal Majority mencakup artikel hasil penelitian, laporan kasus dan tinjauan pustaka.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 106 Documents
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PENGARUH PEMBERIAN TEH HITAM (Camellia sinensis) TERHADAP GAMBARAN HISTOPATOLOGI ARTERI KORONARIA TIKUS PUTIH GALUR WISTAR YANG DIINDUKSI MINYAK JELANTAH Yovani Rehuel Br Sitepu; Rizki Hanriko; Ari Wahyuni
MAJORITY Vol 12 No 1 (2023): MAJORITY
Publisher : Majority

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Abstract

Used cooking oil contains free radicals and free fatty acids which can cause damage to the coronary artery. Black tea contains flavonoids and theaflavins are antioxidants that can prevent coronary artery damage. This study aims to determine the effect of giving black tea (Camellia sinensis) on the coronary artery histopathology of Wistar white rats induced by used cooking oil. This study used a Post-test Control Group Design pattern using 25 rats which were divided into 5 groups with 28 days of treatment. The group K- was given 2 ml distilled water. The group K+ was given used cooking oil 1,5 ml/day. The group P1 was given used cooking oil of 1,5 ml/day and black tea 15 mg/day. The group P2 was given used cooking oil of 1,5 ml/day and black tea 30 mg/day. The group P3 was given used cooking oil 1.5 ml/day and black tea 45 mg/day. Observations were made using a microscope by looking at the circumference of the lumen diameter. The results of the mean coronary artery lumen diameter of the rats at K-=116,21±13,17 μm; K+=69,25±7,74 μm; P1=90,72±9,58 μm; P2=102,89±17,69 μm; and P3=125,06±9,67μm. This study used the one-way ANOVA parametric test (p<0,05) and continued with the post-hoc LSD test (p<0,05). There is an effect of giving black tea (Camellia sinensis) on the coronary artery histopathology of Wistar white rats induced by used cooking oil.
Identification of Physical Factors and Individual Characteristics Affecting The Event of Sick Building Syndrome (SBS) In Employees At The Class I Immigration Office of TPI Bandar Lampung Anisa Adelia; Khairun Nisa Berawi; Dwita Oktaria; Winda Trijayanthi Utama
MAJORITY Vol 12 No 1 (2023): MAJORITY
Publisher : Majority

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Abstract

Sick Building Syndrome (SBS) is a collection of symptoms that can be experienced by someone who works in a building. A person is declared to have Sick Building Syndrome (SBS) if they have complaints of at least two or three symptoms of the total symptoms (eye irritation such as sore, red or watery eyes, throat irritation, pain when swallowing, itchy throat, sneezing, dry cough, shortness of breath, heaviness in chest, dry, red and itchy skin, nausea, fatigue, difficulty concentrating, drowsiness, dizziness). SBS can be enforced if the various complaints that exist are felt by around 20% -50% of users of a building, and these complaints disappear when workers leave the building. This study was an observational analytic study with a cross sectional design. The sampling technique used was total sampling with a minimum sample size of 63 people. Data were collected using the The Miljo-Medicin 040 Questionnaires (MM040EA) questionnaire for individual characteristics and symptoms of SBS and direct measurements for physical factors. Data analysis used chi square test and logistic regression test. Based on the data obtained the p value of each variable which states a relationship, namely gender (0.102), age (0.028), length of work (0.002), smoking habits (0.006), psychosocial conditions (0.007), air flow rate (0.029 ), lighting (0.042). The results of the multivariate analysis test showed that the length of work variable was the most dominant factor on SBS with a p value (0.015). The variables that affect the incidence of SBS are age, length of work, smoking habits, psychosocial conditions, air flow rate, lighting and the most dominant variable is length of work.
Pengaruh Pemberian Ekstrak Biji Kopi Robusta (Coffea canephora) Lampung terhadap Aktivitas Enzim Katalase Hippocampus Tikus Putih (Rattus norvegicus) Jantan Galur Sprague dawley yang Diinduksi Monosodium Glutamat Syazili Mustofa; Ni Sayu Putu Desya Laksmi Putri; Lucky Togihon; Wayan Ferly Aryana; Rizki Putra Sanjaya; Tito Tri Saputra
MAJORITY Vol 12 No 1 (2023): MAJORITY
Publisher : Majority

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Abstract

Almost 60 million people worldwide have recovered from pulmonary tuberculosis since 2000, but many of them develop post-tuberculous lung disease. The disease results from a complex interaction between the disease-causing organism, the host, and environmental factors, and this affects the long-term airway. People with this disease have a shorter life expectancy and an increased risk of tuberculosis recurrence. Bronchiectasis is a disease of the dilation of the bronchial tubes which is characterized by decreased mucociliary transport function. It can also be caused by a bacterial infection with Post Tuberculosis Obstructive Syndrome (SOPT). SOPT is a lung disorder characterized by chronic airway obstruction due to complications arising from post-treatment pulmonary tuberculosis. This case describes a patient with bronchiectasis and SOPT who came with symptoms of shortness of breath accompanied by a long cough. From the results of the physical examination and supporting examinations, a working diagnosis was obtained in the form of infected brochiectasis accompanied by post-tuberculosis obstructive syndrome. The patient was then given therapy in the form of oxygenation, nebulized bronchodilators, corticosteroid injections, and antibiotics. In addition, patients are also given chest physiotherapy and a high-calorie, high-protein diet.
Karakteristik Penderita Adenokarsinoma Paru Di RSUD Dr. H. Abdul Moeloek Lampung Periode Tahun 2014-2019 Trixie Almira; Rizki Hanriko; Ari Wahyuni; Retno Ariza Soeprihatini
MAJORITY Vol 12 No 1 (2023): MAJORITY
Publisher : Majority

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Abstract

Adenonacarcinoma of the lung is the largest type of lung carcinoma. Risk factors of lung adenocarcinoma are include age, gender and smoking history. Lung adenocarcinoma therapy generally consists of chemotherapy and developed targeted therapy, such as targeting genes that activate proliferation such as Epidermal Growth Factor Receptor (EGFR). The research is a descriptive and observational analytic study with a cross sectional approach. The number of samples obtained was 82 samples obtained using the Total Random Sampling technique. Analyze descriptive statistical test results showed that most patients with lung adenocarcinoma were found in the 40-60 years age group (61.0%), the most sex was found in men (64.6%), had a history of smoking (54.9%), some large were diagnosed at stage IV (80.5%), there was no EGFR gene mutation (54.9%), and had survival rate > 1 year diagnosed (62.2%). The results showed a relationship between gender (p value = 0.040), smoking history (p value = 0.002), survival rate (0.012) with EGFR gene mutations. Meanwhile, there was no significant corelation between sex (p value = 0.448) and the EGFR gene mutation. Lung adenocarcinoma is most commonly found in males in the adolescent age group of 40-60 years with a history of smoking, stage IV, no EGFR gene mutation and survival rate >1 year and there is an association between sex, smoking history, survival rate with EGFR gene mutations in patients lung adenocarcinoma.
Hubungan Tingkat Pengetahuan Gizi Ibu Hamil dengan Taksiran Berat Janin di Wilayah Kerja Puskesmas Kedaton Kota Bandar Lampung Desta Stallaza Alifka; Reni Zuraida; Efriyan Imantika; Ratna Dewi Puspita Sari
MAJORITY Vol 12 No 1 (2023): MAJORITY
Publisher : Majority

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59042/mj.v12i1.175

Abstract

One of the activities routinely carried out in antenatal care is the measurement of Fundus Uterine Height (FUH) to determine Estimated Fetal Weight (EFW). Fetal weight growth can be indirectly affected by the basic nutritional knowledge of  pregnant  women  about the  importance of  fulfillinf nutrition during pregnancy to  support the  health  and development  of the  fetus. The aim of the study was to determine the relation between the level of nutritional knowledge of pregnant women and the estimated fetal weight at Kedaton Primary Health Center Bandar Lampung City. The research design used was analytic observational with cross sectional approach using primary data by measuring the knowledge of pregnant  women  using  a  questionnaire  consisting of 28 question  items  and  secondary  data  in  the   form  of uterine fundal height in the KIA book. Sampling was conducted at the Kedaton Primary Health Center in 2020. The sample was taken using purposive sampling with a total sample of 46 samples that met the inclusion and exclusion criteria. Data analysis used Chi Square with α = 0.05 and CI = 95%. The results  showed  that  there  were  8.7%  mothers with good nutritional knowledge, 71.7% mothers with moderate nutritional knowledge and 19.6% mothers with poor nutrition knowledge. Then pregnant women with small EWF during pregnancy and large EFW during pregnancy consisted of 10.9% and 78.3% respectively of mothers with EFW according to gestational age. Bivariate analysis showed that there was a relationship between the level of nutritional knowledge in pregnant women and the estimated fetal weight at Kedaton Health Center with a value of p = 0.003. There is a correlation between the level of nutritional knowledge of pregnant women with the estimated fetal weight.
Penatalaksanaan Holistik Wanita Usia 48 Tahun Dengan Hipertensi dan Dispepsia Melalui Pendekatan Kedokteran Keluarga Sella Kintania Sari; Azelia Nusadewiarti
MAJORITY Vol 12 No 1 (2023): MAJORITY
Publisher : Majority

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Abstract

Hypertension is a condition where systolic blood pressure is ≥ 140 mmHg and/or diastolic is ≥ 90 mmHg. Dyspepsia is a collection of symptoms that lead to upper digestive tract disorders including pain or discomfort in the gastro-duodenal area, burning sensation, fullness, early satiety, nausea, and vomiting. This case report identifies risk factors, clinical problems, and provides management to patients by implementing holistic family doctor services based on evidence based medicine through a patient centered and family approach. Primary data were obtained through autoanamnesis, physical examination, and home visits to complete family data, psychosocial data, and environmental data. Secondary data was obtained from patient medical records at the Puskesmas. The assessment is based on a holistic diagnosis from the beginning, process, and end of the study both quantitatively and qualitatively. Holistic management was carried out, namely intervention using calendars, posters, and cups on a 48-year-old female patient who complained of headaches, heartburn, and nausea. The patient's internal risk factors include pre-elderly age, curative treatment patterns, overweight BMI, infrequent exercise & physical activity, inappropriate diet & eating habits, and wrong perceptions about the disease. The patient's external risk factors include stress, lack of family support and knowledge, and family history of hypertension. The evaluation obtained increased understanding of the disease and changes in behavior that have an impact on the success of therapy.

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