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Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Published by Asosiasi Riset Ilmu Kesehatan Indonesia
ISSN : 3031013X     EISSN : 30310148     DOI : 10.61132
Core Subject : Health,
Health Professions Nursing Public Health
Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Alam, Biokimia, Analisis Kimia, Kimia Fisika, Biologi, Mikrobiologi, Jaringan Budaya, Botani dan Hewan terkait Produk Farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Gizi dan Kesehatan Masyarakat.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 424 Documents
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Penerapan Pijat Bayi terhadap Penurunan Kadar Bilirubin pada Bayi Hiperbilirubinemia : Studi Kasus Reno Cahyo; Citra Setyo Dwi Andhini; Endah Sari Purbaningsih
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i1.2380

Abstract

Hyperbilirubinemia is a common condition in newborns characterized by yellow discoloration of the skin and sclera due to elevated serum bilirubin levels. If untreated, severe hyperbilirubinemia can lead to kernicterus and permanent brain damage. Phototherapy as the main treatment has limitations such as dehydration and skin rashes, necessitating complementary therapies such as infant massage. This study aimed to identify the application of infant massage in reducing bilirubin levels in an infant with hyperbilirubinemia. A descriptive case study method was applied to 1 male infant aged 2 days with total serum bilirubin of 9.87 mg/dL undergoing phototherapy at Dahlia Room, Kardinah Hospital, Tegal. Infant massage was performed for 10-15 minutes once daily for 4 consecutive days using pure coconut oil with moderate pressure. Bilirubin levels were measured daily using a Transcutaneous Bilirubinometer JM-105. Results showed a progressive decrease in bilirubin levels from 9.87 mg/dL to 5.20 mg/dL (total reduction of 4.67 mg/dL). Bowel movement frequency increased from 2 to 4-5 times/day, sleep quality improved from restless to restful, body temperature remained stable within normal range, and infant comfort improved. The combination of infant massage and phototherapy demonstrated synergistic effects in accelerating bilirubin excretion through enhanced intestinal peristalsis and disrupting enterohepatic circulation. Infant massage is effective, safe, and low-cost as a complementary therapy for hyperbilirubinemia and can be performed by trained healthcare providers or parents after proper education. This study provides daily clinical descriptions of changes in bilirubin levels, defecation frequency, sleep quality, and infant comfort during the implementation of baby field massage combined with phototherapy.
Penerapan Terapi Relaksasi Tarik Nafas dalam untuk Mengurangi Ansietas Pasien Intradyalitic dengan Gagal Ginjal Kronis: Studi Kasus Fidia Az-Zahra; Dwiyanti Purbasari
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i1.2381

Abstract

Background: Chronic Kidney Disease (CKD) is a progressive health problem that often requires long-term hemodialysis therapy. The hemodialysis process may cause psychological problems, particularly anxiety, which can affect treatment adherence, emotional well-being, and quality of life. Deep breathing relaxation therapy is a non-pharmacological nursing intervention that can help reduce anxiety and promote relaxation. Objective: To describe the implementation of deep breathing relaxation therapy in reducing anxiety among intradialytic patients with chronic kidney disease. Methods: This study employed a case study approach using the nursing care process, including assessment, nursing diagnosis, planning, implementation, and evaluation. Deep breathing relaxation therapy was administered during hemodialysis sessions, and anxiety levels were evaluated before and after the intervention using appropriate anxiety indicators. Results: The implementation of deep breathing relaxation therapy showed a reduction in patients’ anxiety levels. Patients appeared calmer, were able to control anxious feelings more effectively, demonstrated improved emotional responses, and reported greater comfort during hemodialysis procedures. Implications: Deep breathing relaxation therapy is a simple, safe, and effective non-pharmacological nursing intervention for reducing anxiety in patients with chronic kidney disease undergoing hemodialysis. This intervention may improve patient comfort, support psychological well-being, and enhance the quality of holistic nursing care.
Intervensi Non-Farmakologis untuk Menurunkan Fatigue ada Pasien Gagal Ginjal Kronik Sri Alifia Anjani Yahya; Erida Fadila; Dwiyanti Purbasari
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i1.2382

Abstract

Chronic kidney failure patients undergoing hemodialysis often experience fatigue that impacts physical, psychological, and quality of life. The treatment of fatigue does not only depend on pharmacological therapy, but can also be done through non-pharmacological interventions that are safer and have fewer side effects. This study aims to analyze the effectiveness of non-pharmacological interventions in reducing fatigue in hemodialysis patients. The research method uses Systematic Literature Review (SLR) with the PRISMA approach. Articles were obtained from Google Scholar, PubMed, ScienceDirect, and Garuda databases. A total of 11 articles that met the inclusion criteria were analyzed in depth. The results of the study showed that various non-pharmacological interventions such as relaxation therapy, exercise, acupressure, music therapy, and recreational therapy were proven to be effective in reducing fatigue and improving the comfort, sleep quality, physical capacity, and quality of life of hemodialysis patients. These findings confirm that non-pharmacological interventions can be used as complementary, safe, and effective companion therapies in clinical practice. The implications of this study provide a basis for health workers to integrate non-pharmacological interventions in the treatment program for patients with chronic kidney failure, so that it is expected to improve the overall quality of life.
Penerapan Positioning Therapy terhadap Peningkatan Perfusi Serebral pada Pasien Stroke Iskemik Sindi Lailatul Muasanah; Erida Fadila; Dwiyanti Purbasari
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i1.2383

Abstract

Ischemic stroke is one of the neurological conditions that can cause cerebral perfusion disorders due to reduced blood flow to the brain. One of the evidence-based nursing interventions used to optimize cerebral perfusion is positioning therapy, specifically the 30° head up position. This study aims to determine the effectiveness of positioning therapy on increasing cerebral perfusion in ischemic stroke patients. The research method is in the form of literature review of 12 articles published in the 2020–2025 period, with data sources from Google Scholar, PubMed, ScienceDirect, and Garuda. The results of the study show that most studies support the effectiveness of the 30° head up position in improving cerebral perfusion. This is characterized by an increase in Cerebral Perfusion Pressure (CPP), an increase in the Glasgow Coma Scale (GCS), an increase in oxygen saturation (SpO₂), and a decrease in Intracranial Pressure (ICP). These findings confirm that positioning therapy is a simple, safe, and evidence-based nursing intervention to improve cerebral perfusion in ischemic stroke patients. The implication of this study is the need to apply positioning therapy as part of the standard nursing practice in the management of ischemic stroke patients to support the improvement of clinical conditions and quality of life.
Penerapan Evidance Based Nursing ROM Pasif untuk Meningkatkan Kekuatan Otot pada Pasien Post Operasi Fraktur Femur Saidah Saniyah; Erida Fadila; Dwiyanti Purbasari
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 2 (2026): Maret: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i2.2384

Abstract

Background: Patients undergoing Open Reduction and Internal Fixation (ORIF) for femoral fractures often experience impaired physical mobility due to pain, immobilization, and decreased muscle strength. Passive Range of Motion (ROM) exercises are one of the nursing interventions that can help improve muscle strength and accelerate the recovery of extremity function. Objective: To describe the implementation of passive ROM exercises in improving muscle strength among post-ORIF femoral fracture patients. Methods: This study used a descriptive case study design involving three post-ORIF femoral fracture patients with impaired physical mobility. Passive ROM exercises were administered for 3×24 hours and evaluated using Manual Muscle Testing (MMT). Results: All patients showed an improvement in muscle strength from an average score of 2/5 to 3/5. In addition, joint range of motion increased, pain decreased, and mobility gradually improved. Implications: Passive ROM exercises can be used as a nursing intervention to improve muscle strength and physical mobility while supporting the rehabilitation process in post-operative femoral fracture patients.
Penerapan Range of Motion (ROM) Pasif pada Asuhan Keperawatan Pasien Stroke dengan Gangguan Mobilitas Fisik di Ruang Stroke Unit RSD Gunung Jati Kota Cirebon Rama Sukma Diraja; Nonok Karlina
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 2 (2026): Maret: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i2.2385

Abstract

Stroke is one of the degenerative diseases that is the main cause of death and disability in Indonesia. Based on WHO data in 2022, there are more than 12 million new cases of Stroke every year worldwide, while the prevalence of Stroke in Indonesia reaches 12.1 per 1,000 population (Riskesdas 2018). One of the nursing problems that often arise in Stroke patients is impaired physical mobility due to muscle weakness and immobilization. Range of Motion (ROM) exercises are a rehabilitation intervention that has been shown to be effective in increasing muscle strength and preventing joint stiffness. This study aims to describe the implementation of ROM exercises in Stroke patients with physical mobility disorders at Gunung Jati Hospital, Cirebon City in 2026. The research design was in the form of a qualitative descriptive case study with the subject Mr. A, a 48-year-old male with a diagnosis of non-hemorrhagic Stroke. Passive and active ROM interventions were carried out for three days in a structured manner. The evaluation showed an improvement in the patient's movement ability and muscle strength, so that nursing problems were partially resolved. The results of the study confirm that regular and repeated ROM exercises are effective in improving physical mobility and muscle strength in non-hemorrhagic Stroke patients. Education to patients and families also plays an important role in supporting the rehabilitation and recovery process.
Penerapan Alih Baring dan Pemberian Minyak Zaitun untuk Mencegah Gangguan Integritas Kulit pada Pasien Stroke Non Hemoragik: Studi Kasus di Ruang Stroke Unit RSD Gunung Jati Kota Cirebon 2026 Jeesyca Vivi Lianti Nova Hermanto; Dewi Erna Marisa; Ahmad Syaripudin
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 2 (2026): Maret: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i2.2386

Abstract

Background: Non-hemorrhagic Stroke often causes mobility impairment that increases the risk of impaired skin integrity and pressure ulcers due to prolonged bed rest. Repositioning and olive oil application are evidence-based nursing interventions that may help maintain skin integrity and prevent skin damage in immobilized patients. Objective: To determine the effectiveness of repositioning and olive oil application in preventing impaired skin integrity among patients with non-hemorrhagic Stroke. Methods: A case study was conducted on one patient with non-hemorrhagic Stroke who experienced impaired skin integrity in the Stroke Unit of Gunung Jati Regional Hospital, Cirebon City. Data were collected through interviews, observations, physical examinations, and documentation studies. Nursing interventions included repositioning every two hours and olive oil application to pressure-prone areas for three consecutive days. Results: The interventions resulted in decreased redness on bony prominence areas, improved skin moisture, and maintenance of intact skin integrity without signs of tissue damage or pressure ulcer development. Implications: Repositioning and olive oil application are effective nursing interventions for maintaining skin integrity and preventing pressure ulcers in non-hemorrhagic Stroke patients with limited mobility.
Penerapan Evidance Based Nursing Squeeze Ball Exercise terhadap Peningkatan Kekuatan Otot pada Pasien Stroke Non Hemoragik Nur Laeli; Citra Setyo Dwi Andini; Endah Sari Purbaningsih
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 2 (2026): Maret: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i2.2387

Abstract

Nonhemorrhagic stroke is a disruption of blood flow to the brain due to blockage of blood vessels that has an impact on muscle weakness, impaired physical mobility, and limitations in daily activities. One of the nonpharmacological interventions that can be applied to improve upper extremity motor function is squeeze ball exercise. This study aims to describe the application of squeeze ball exercise in nonhemorrhagic stroke patients with physical mobility disorders in the stroke room. The research method is in the form of a descriptive case study with a nursing care approach in one patient. Data was collected through interviews, observations, physical examinations, documentation, and the application of squeeze ball exercises for four days with a duration of 5–10 minutes per session. Evaluation was carried out through observation of changes in the patient's muscle strength, grasping ability, and mobility. The results showed an increase in upper extremity muscle strength based on Manual Muscle Testing (MMT), from a scale of 2 to a scale of 4 after the intervention. The improvement was characterized by better grasping of rubber balls, more active hand movements, and increased patient independence in daily activities. During implementation, the patient shows a cooperative attitude and gradual motor improvement. This case study confirms that squeeze ball exercise can be used as a supportive therapy in the rehabilitation of nonhemorrhagic stroke patients because it contributes to increasing muscle strength, grasping ability, and physical mobility.
Penerapan Pursed LIP Breathing terhadap Penurunan Sesak Napas pada Pasien Penyakit PPOK di Ruang HCU Mudrikah AZ; Liliy Wahyu Romadhon; Citra Setyo Dwi Andini
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 3 (2026): Mei : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i3.2388

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory disorder characterized by persistent airflow limitation and commonly associated with dyspnea. Uncontrolled dyspnea may decrease patients' functional capacity and quality of life. One of the non-pharmacological interventions that can be applied to reduce dyspnea is the Pursed Lip Breathing (PLB) technique. This Final Nursing Scientific Project aimed to describe the application of Pursed Lip Breathing in reducing dyspnea among COPD patients at Gunung Jati Regional Hospital, Cirebon. This study used a descriptive case study approach through the nursing process, including assessment, nursing diagnosis, intervention, implementation, and evaluation. The Pursed Lip Breathing technique was implemented according to the standard operating procedure in COPD patients with an ineffective breathing pattern nursing diagnosis. The results showed an improvement in respiratory status, indicated by decreased dyspnea, reduced respiratory rate, increased oxygen saturation, and decreased use of accessory respiratory muscles. The patient also appeared more comfortable and was better able to control breathing patterns following the intervention. In conclusion, the Pursed Lip Breathing technique is an effective non-pharmacological nursing intervention for reducing dyspnea in patients with COPD.
Penerapan Terapi Murottal Surah Ar-Rahman terhadap Penurunan Ansietas pada Pasien Stroke Hemoragik di Ruang Stroke Unit : Studi Kasus Nurul Arsy Azizah; Citra Setyo Dwi Andhini; Endah Sari Purbaningsih
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 3 (2026): Mei : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i3.2389

Abstract

Hemorrhagic stroke is a condition of bleeding in the brain that can cause neurological disorders as well as psychological problems, one of which is anxiety. Unresolved anxiety can affect physiological conditions and hinder the patient's recovery process. Murottal therapy is a spiritual-based non-pharmacological intervention that can be used to help reduce anxiety levels. This study aimed to describe the implementation of murottal therapy in reducing anxiety among patients with hemorrhagic stroke in a stroke unit.This study employed a descriptive method with a case study approach involving a hemorrhagic stroke patient experiencing anxiety. Data were collected through nursing assessment, observation, the Zung Self-Rating Anxiety Scale (ZSAS), and the implementation of Surah Ar-Rahman murottal therapy. The therapy was administered for 10–15 minutes daily for three consecutive days.The results showed a 24.1% reduction in anxiety levels following the administration of murottal therapy. This was indicated by a decrease in the ZSAS score from 58 to 44 after three days of intervention. The patient appeared calmer, more relaxed, more comfortable, and was able to rest better. Murottal therapy can be used as a complementary nursing intervention to help reduce anxiety and support the recovery process in patients with hemorrhagic stroke. These findings suggest that Surah Ar-Rahman murottal therapy has the potential to become a simple, safe, cost-effective, and easily applicable spiritual nursing intervention as a complementary therapy for patients with hemorrhagic stroke.

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