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The International Journal of Medical Science and Health Research
ISSN : 30481376     EISSN : 30481368     DOI : -
Core Subject : Health,
The International Journal of Medical Science and Health Research, published by International Medical Journal Corp. Ltd. is dedicated to providing physicians with the best research and important information in the world of medical research and science and to present the information in a format that is understandable and clinically useful. Committed to publishing multidisciplinary research that spans the entire spectrum of healthcare and medicine access, The American Journal of Medical Science and Health Research aims at an international audience of pharmacists, clinicians, medical ethicists, regulators, and researchers, providing an online forum for the rapid dissemination of recent research and perspectives in this area.
Articles 529 Documents
The Analysis Study of Prevalence, Diagnosis and Management of Gestational Diabetes: A Comprehensive Years Systematic Review Bayu Setyo Nugroho
The International Journal of Medical Science and Health Research Vol. 8 No. 4 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/gpgfhp26

Abstract

Background: Gestational diabetes mellitus (GDM), a common endocrine disorder during pregnancy, is associated with the placental secretion of diabetogenic hormones, increasing insulin resistance. The worldwide prevalence of GDM is believed to be between 7% and 10% of all pregnancies, with diagnostic heterogeneity affecting prevalence and outcome estimates. The absence of globally recognized gold standards for GDM diagnosis leads to variability in identifying affected women. Methods: This systematic review complied with PRISMA 2020 requirements, concentrating solely on full-text papers published in English from 2014 to 2024. Editorials and review articles lacking a DOI were eliminated to guarantee the use of high-quality sources. A literature review was performed using esteemed databases such as ScienceDirect, PubMed, and SagePub to discover pertinent studies. Result: The initial database search identified more than 300 relevant publications on the topic. Following a comprehensive three-stage screening process, eight studies were selected that met the specified inclusion criteria for in-depth analysis. The studies were subjected to a thorough critical evaluation, enabling an in-depth analysis of the prevalence, diagnosis, and management of gestational diabetes. This targeted methodology ensured that the analysis employed strong evidence closely aligned with the study's objectives. Conclusion: GDM is a common medical complication in pregnancy that has a significant effect on both maternal and neonatal health outcomes globally. The prevalence ranges from 2% to 24.5%, demonstrating a continuous correlation between maternal glucose levels and adverse outcomes. Lifestyle interventions, dietary modifications, and regular physical activity are essential for the management of GDM.
A Comprehensive Systematic Review of Risk Factor and Management Approach of Gout Arthritis in General Practice Rini Armaida Purba; Charles Sanjaya Seikka
The International Journal of Medical Science and Health Research Vol. 9 No. 1 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/jacyfa67

Abstract

Background: Gout arthritis is a chronic inflammatory joint disease caused by the accumulation of monosodium urate (MSU) crystals. The main factor that triggers the formation of MSU crystals is high serum uric acid levels (hyperuricemia). This systematic review aims to identify and analyze the risk factors, management, and prevention of gout arthritis based on literature published in the last ten years. Methods: This study followed the PRISMA 2020 standard, examining English-language literature from 2015 to 2025. This study excluded editorials, reviews from the same journal, and submissions without DOI. PubMed, SagePub, SpringerLink, and Google Scholar were used as literature sources. Results: Initially obtaining 360 articles from online databases (PubMed, SagePub, SpringerLink, and Google Scholar), eight relevant papers were selected after three rounds of screening for full-text analysis. Conclusions: Treatment of gouty arthritis is done through a combination of pharmacological therapy and lifestyle changes. Prevention involves managing risk factors such as hypertension, obesity, and alcohol consumption. Education and appropriate long-term treatment can reduce attacks and improve the patient's quality of life.
The Analysis Study of Diet and Lifestyle Interventions for Insulin Resistance Patients with Nonalcoholic Fatty Liver: A Comprehensive Systematic Review Aprilia Indah Purnomo; Charles Sanjaya Seikka
The International Journal of Medical Science and Health Research Vol. 9 No. 1 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/x8xtak54

Abstract

Introduction: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease globally, affecting 20–30% of adults in developed countries and rising to 75% in individuals with obesity and 50–75% in those with type 2 diabetes mellitus (T2DM). The disease ranges from simple steatosis to non-alcoholic steatohepatitis (NASH) and may progress to fibrosis, cirrhosis, and liver failure. Insulin resistance (IR) plays a central role in its progression. This review examines the effects of diet and lifestyle interventions on IR and liver function in NAFLD patients. Methods: A systematic review adhering to PRISMA 2020 guidelines was conducted. Studies from 2015 to 2025 focusing on dietary or lifestyle interventions in NAFLD patients were included. Outcomes assessed included changes in IR (via HOMA-IR) and liver function (ALT, AST, GGT). Results: Eight relevant studies were included. Dietary interventions, such as the Mediterranean diet and calorie restriction, along with physical exercise, showed significant improvements in IR and liver function. Combined interventions yielded better outcomes compared to single-modality approaches. Discussion: Dietary interventions (Mediterranean diet, low-fat diet) and exercise (aerobic and resistance) significantly impact IR and liver function. The findings highlight the importance of individualized, comprehensive lifestyle interventions for NAFLD management. Conclusion: This review shows the effectiveness of diet and lifestyle interventions in managing NAFLD through improvements in insulin sensitivity and liver health. Combined approaches should be prioritized to optimize patient outcomes and long-term adherence to treatment.
Screening and Etiology of Congenital Heart Disease in Developing Countries : A Comprehensive Systematic Review Dzakiyyah Fiddin; Dhanista Hastinata Sukarna Putra; Irkhamyudhi Primasakti
The International Journal of Medical Science and Health Research Vol. 9 No. 1 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/6e8xxb74

Abstract

Introduction: The increasing number of newborns with congenital heart disease (CHD) shows that the global burden of CHD is still significant. This indicates that screening and prevention have not been carried out optimally. This study aims to determine the differences of screening and etiology of congenital heart disease (CHD) between developed and developing countries. Methods: A systematic review adhering to PRISMA 2020 guidelines was conducted. Studies from 2015 to 2025 focusing on the screening and etiology of CHD in developing and developed countries were included. Results: Twenty-three relevant studies were included. Combination of pulse oximetry (PO) and auscultation, or PO alone were the most common postnatal screening tools in developed and developing countries. For prenatal screening, ultrasound was commonly used. Artificial intelligence and genetic testing were only used in developed countries. The etiology such as genetics, maternal lifestyle or conditions were discussed. Conclusion: The urgent need for affordable early detection of congenital heart disease (CHD) in developing countries cannot be overstated, as it holds the potential to significantly reduce the global burden of this condition. By implementing comprehensive prenatal and postnatal screening programs, we can identify at-risk infants early, enabling timely interventions and improved health outcomes. Addressing this critical issue not only enhances individual lives but also strengthens healthcare systems and fosters healthier communities.
Diagnostic Imaging of Severe Pneumonia COVID-19: A Comprehensive Systematic Review Claudia Bella Laurentia; Tri Harjanto; Tiarma Saulina
The International Journal of Medical Science and Health Research Vol. 9 No. 2 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/esrc1540

Abstract

Background: COVID-19, caused by SARS-CoV-2, has become a global health crisis since its emergence in December 2019. Severe pneumonia is a critical manifestation of the disease, often necessitating diagnostic imaging for effective management. This systematic review evaluates the diagnostic imaging features of severe pneumonia in COVID-19 using chest X-ray (CXR), computed tomography (CT), lung ultrasound (LUS), and magnetic resonance imaging (MRI). Methods: This review follows PRISMA 2020 guidelines. Studies from 2019–2024 were screened for peer-reviewed evaluations of imaging findings in severe COVID-19 pneumonia. Results: Eight studies were included. Key findings demonstrated the utility of LUS in detecting early abnormalities like B-lines, critical for bedside monitoring. CXR served as a prognostic tool with radiographic severity scores correlating with adverse outcomes. CT provided detailed anatomical insights, identifying ground-glass opacities (GGO), consolidations, and disease severity markers. MRI, while less commonly used, showed comparable sensitivity and specificity to CT, with advantages in radiation-free imaging for specific populations. Discussion: The reviewed studies highlight the complementary roles of imaging modalities in managing COVID-19 pneumonia. Key imaging features include ground-glass opacities, consolidations, and crazy-paving patterns, predominantly in peripheral and lower lung regions.        Conclusion: Imaging modalities play complementary roles in managing severe COVID-19 pneumonia. LUS is ideal for bedside assessments, CXR aids in prognostication, CT remains the gold standard for detailed evaluation, and MRI offers a viable alternative for radiation-sensitive cases. Understanding these modalities' applications can enhance diagnostic accuracy and clinical outcomes.
The Analysis Study of Underlying Disease, Symptoms and Mortality Rate of COVID-19: A Comprehensive Systematic Review Anissa Paranoan; Anelsa Paranoan; Adeline Arung
The International Journal of Medical Science and Health Research Vol. 9 No. 2 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/xh7ka962

Abstract

Background: The prevalence of underlying diseases in 22% of the global population increases their risk of severe COVID-19 outcomes. These conditions, often indicating a decline in physiological systems, compromise health and increase susceptibility to severe complications. A holistic approach is needed to understand their collective influence. Methods: This systematic review adhered to PRISMA 2020 guidelines, focusing exclusively on full-text articles published in English between 2014 and 2024. Editorials and review articles without a DOI were excluded to ensure the utilization of high-quality sources. A literature review was conducted utilizing reputable databases including ScienceDirect, PubMed, and SagePub to identify relevant studies. Result: The initial database search yielded approximately 1,300 publications relevant to the topic. Following a rigorous three-stage screening process, eight studies met the predefined inclusion criteria and were selected for in-depth analysis. Each study underwent a comprehensive critical evaluation, allowing for a detailed examination of the relationships between underlying diseases, symptoms, and COVID-19 mortality rates. This systematic approach ensured that the analysis was based on high-quality evidence, directly aligned with the study’s objectives, and contributed to a more precise and reliable understanding of the subject. Conclusion: The study highlights the impact of underlying diseases on COVID-19 outcomes, highlighting the need for proactive management strategies. The study also highlights the global trend in symptomatology and risk factors, emphasizing the need for region-specific healthcare policies. Understanding the interplay between diseases and outcomes is crucial for effective disease management.
Cardiac Rhabdomyoma in 9 Months Infant: From Echocardiography Perspective Jordy Liong; Andi Alief Utama Armyn; Rheza Rivaldi Salam; Jauhar Mario; Herwin Irawan
The International Journal of Medical Science and Health Research Vol. 9 No. 2 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/cpth0d34

Abstract

Background: The most prevalent benign cardiac tumor in neonates, cardiac rhabdomyoma, is frequently associated with tuberous sclerosis complex (TSC). Based on their dimensions and positioning, these tumors may result in obstructive cardiac lesions, arrhythmias, or hemodynamic instability. Echocardiography is the primary diagnostic instrument for detecting and monitoring cardiac rhabdomyomas, as well as for differentiating them from other intracardiac malignancies. Case Report : This case report describes a 9-month-old newborn diagnosed with cardiac rhabdomyoma, focusing on the echocardiographic findings, clinical presentation, and therapy strategy. Echocardiographic imaging identified many hyperechoic masses within the ventricles; further echocardiographic evaluations demonstrated spontaneous regression, thereby corroborating the diagnosis. Conclusion : The absence of genetic evidence between MRI and TSC hinders a definitive connection. This case underscores the importance of non-invasive imaging in guiding the diagnosis and treatment of pediatric cardiac cancers. 
The Analysis Study of Relationship of Psoriasis and Hypertension: A Comprehensive Systematic Review Melinda Angelin; Muhammad Faiz Haidar Rafi
The International Journal of Medical Science and Health Research Vol. 9 No. 3 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/1v8p7373

Abstract

Background: Psoriasis patients have a higher prevalence of hypertension, a significant risk factor for cardiovascular disease. The association between psoriasis and hypertension is complex, with psoriasis often presenting with additional risk factors. Treatment approaches are complex, and understanding the bidirectional relationship between psoriasis and hypertension is crucial for optimizing treatment strategies and improving patient care. Methods: This systematic review adhered to PRISMA 2020 guidelines, focusing exclusively on full-text articles published in English between 2014 and 2024. Editorials and review articles without a DOI were excluded to ensure the utilization of high-quality sources. A literature review was conducted utilizing reputable databases including ScienceDirect, PubMed, and SagePub to identify relevant studies. Result: The initial database search yielded over 1,000 relevant publications on the topic. Following a rigorous three-stage screening process, eight studies met the predefined inclusion criteria and were selected for in-depth analysis. Each study underwent a comprehensive critical evaluation, enabling a thorough examination of the relationship between psoriasis and hypertension. This systematic approach ensured that the analysis was grounded in high-quality evidence, closely aligned with the study's objectives, and capable of providing meaningful insights into this complex association. Conclusion: Psoriasis and hypertension are linked due to various factors, including confounding variables, shared inflammatory pathways, and treatment-related factors. Further research is needed to understand causal mechanisms and the impact of disease severity on hypertension risk. Understanding these factors will help healthcare providers develop personalized treatment approaches and improve patient outcomes for those affected by both conditions.
Omega-3 and DHA Supplementation in Pregnancy: A Systematic Review of Its Role in Preventing Preeclampsia and Gestational Diabetes Deni Wirhana; Bayu Setyo Nugroho; Tuswandi Ahmad Waly
The International Journal of Medical Science and Health Research Vol. 9 No. 3 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/2909pd25

Abstract

Background: Omega-3 fatty acids, such as docosahexaenoic acid (DHA), plays a crucial role in fetal development and pregnancy maintenance, potentially reducing the risk of complications like gestational diabetes mellitus (GDM) and preeclampsia. Supplementation of these fatty acids may improve pregnancy outcomes by promoting fetal growth, prolonging gestational age, and positively influencing neonatal birth weight. However, the clinical evidence supporting the role of omega-3 supplementation in preventing preeclampsia and GDM remains inconclusive. Methods: A preliminary database search identified over 100 relevant studies. Following a rigorous three-stage screening process, eight studies meeting the predefined inclusion criteria were selected for in-depth analysis. Each underwent a comprehensive critical assessment to examine the impact of Omega-3 and DHA supplementation on preventing preeclampsia and gestational diabetes. This systematic approach ensured that the analysis was based on high-quality data, aligned with the study’s objectives, and provided meaningful insights. Result: The final selection comprised eight studies that met the inclusion criteria. A thorough evaluation of these studies allowed for an in-depth investigation of Omega-3 and DHA supplementation's role in preventing preeclampsia and gestational diabetes. This structured analysis reinforced the study’s reliability, ensuring that conclusions were drawn from robust and credible evidence. Conclusion: DHA supplementation plays a crucial role in pregnancy, supporting placental function and maternal metabolic health. However, its preventive role in preventing preeclampsia and GDM remains uncertain. Future research should explore potential benefits and evidence-based guidelines.
The Analysis Study of Surgical Intervention of Degenerative Lumbar Spinal Stenosis: A Comprehensive Systematic Review Muliagus Rimbana Chekmat; Imam Hidayat
The International Journal of Medical Science and Health Research Vol. 9 No. 3 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/7qxjfa10

Abstract

Background: Degenerative lumbar spinal stenosis (DLS) is a progressive condition characterized by narrowing of the spinal canal, leading to nerve compression and significant morbidity. Surgical intervention is often required for patients with refractory symptoms. Various surgical techniques have been developed, including laminectomy, discectomy, interspinous spacers, minimally invasive lumbar decompression (MILD), endoscopic decompression, and pedicle screw-rod instrumentation with fusion. However, the optimal surgical approach remains a subject of debate. Methods: This systematic review was conducted according to PRISMA 2020 guidelines. A comprehensive search was performed in PubMed, Embase, Cochrane Library, Web of Science, and Scopus to identify studies published between 2015 and 2025 that evaluated surgical interventions for DLS. Eligible studies included randomized controlled trials (RCTs), cohort studies, or case-control studies assessing surgical outcomes, including pain relief, functional improvement, complication rates, and reoperation rates. Results: After screening and full-text review, eight studies met the inclusion criteria. The results suggest that minimally invasive and endoscopic techniques are associated with improved postoperative recovery, lower complication rates, and enhanced functional outcomes compared to traditional open procedures. Laminectomy remains a widely used standard approach, but fusion techniques offer additional stability in select cases. The studies demonstrated a low risk of bias overall, particularly among RCTs, while retrospective studies exhibited greater methodological limitations. Conclusion: Minimally invasive and endoscopic surgical approaches for DLS offer promising outcomes in terms of pain relief, functional improvement, and recovery time. However, patient-specific factors, surgeon expertise, and long-term follow-up remain critical in determining the optimal surgical technique. Further high-quality, multi-center RCTs are necessary to strengthen the evidence base and guide clinical decision-making.

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