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Media Penelitian dan Pengembangan Kesehatan
Published by Politeknik Kesehatan Kemenkes Bandung
ISSN : 08539987     EISSN : 23383445     DOI : DOI: https://doi.org/10.34011/jmp2k.v34i3.2287
Core Subject : Health, Science, Social,
Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Environmental Science Medicine & Pharmacology
Media of Health Research and Development is a journal that was developed to disseminate and discuss scientific papers on health development and other research of health. The journal is intended as a medium of communication for those who were interested to study health, among others, for researchers, educators, students, practitioners Department of Health, Public Health Service, and public generally who have an interest in it. The journal is trying to meet the growing need to study health. Vision: Being a leading national journals in the field of health research and leading a reputable international journals. Mission: Providing scientific communication media in health research in order to advance science and technology in related fields. Publishing scientific journal in the field of medical research that seeks to achieve a high impact factor in the development of science and technology.
Arjuna Subject : Kedokteran - Kesehatan Masyarakat, Kesehatan Lingkungan dan Pekerjaan
Articles 402 Documents
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“Cafree Patch” formulation and physical characterization of acne patch based on decaffeinated arabica coffee bean (Coffea arabica L.) extract Rani Rubiyanti; Risnawati Risnawati; Azki Aulia Muti Sani; Herliani Amelia Wardiah
Media Penelitian dan Pengembangan Kesehatan Vol. 36 No. 3 (2026): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v36i3.4392

Abstract

Background: Acne vulgaris is a common skin disorder, particularly among adolescents and young adults in Indonesia. Conventional acne therapies, including antibiotics and synthetic topical agents, may cause adverse effects and bacterial resistance. Therefore, natural alternatives are needed. Decaffeinated Arabica coffee (Coffea arabica L.) extract contains bioactive compounds, particularly chlorogenic acid, with antibacterial and anti-inflammatory activities, showing potential for acne-prone skin care. Objective: This study aimed to formulate and evaluate the physical characteristics of an acne patch containing decaffeinated Arabica coffee bean extract. Methods: This experimental study employed a descriptive approach. Arabica coffee beans from Cigalontang, Tasikmalaya Regency, Indonesia, were decaffeinated through pineapple juice fermentation for 60 hours and extracted using Soxhlet extraction with 70% ethanol. The extract was evaluated for yield and phytochemical constituents before formulation into an HPMC-based acne patch. Characterization included organoleptic evaluation, pH, weight, thickness, and folding endurance. Data were analyzed descriptively and presented as mean ± standard deviation. Results: The extract yield was 9.48%. Phytochemical screening revealed alkaloids, flavonoids, saponins, polyphenols, tannins, and triterpenoids, while steroids were absent. The acne patch exhibited a heart-shaped appearance, yellowish-brown color, characteristic coffee aroma, and a smooth, uniform, adhesive surface. The pH, weight, and thickness were 4.76 ± 0.13, 0.0389 ± 0.0047 g, and 0.06 ± 0.02 mm, respectively, with folding endurance exceeding 300 folds. Conclusion: Decaffeinated Arabica coffee bean extract was successfully formulated into an acne patch with satisfactory physical characteristics based on the evaluated parameters. Further studies are needed to evaluate biological activity, efficacy, stability, and dermal safety.
Patient safety culture as an organizational condition for digital health system readiness in regional hospital Nurhasanah Nurhasanah; Kresna Febriyanto; Silvia Sulistiani
Media Penelitian dan Pengembangan Kesehatan Vol. 36 No. 3 (2026): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v36i3.4442

Abstract

Background: Patient safety is increasingly recognized as a central element in health system development rather than merely an isolated clinical issue. In regional hospitals, the sustainability of digital health system implementation depends not only on technological capacity but also on the organizational environment. Objective: This study aimed to describe patient safety culture as an important organizational condition in the context of digital health system readiness in regional hospitals. Methods: A quantitative descriptive cross-sectional study was conducted involving 219 healthcare professionals and hospital support staff selected using purposive sampling. Data were analyzed descriptively using mean and standard deviation. Results: The findings showed that management commitment (3.72±0.57), system and regulatory support (3.74±0.56), incident reporting (3.72±0.55), and communication (3.71±0.55) were categorized as strong, whereas patient involvement remained moderate. The overall level of digital health system readiness was moderate (3.54±0.54). Conclusion: The findings indicate that patient safety culture and digital health system readiness represent important organizational conditions within regional hospitals. While overall patient safety culture was strong, digital health system readiness remained moderate. These results highlight the need to consider organizational and cultural characteristics alongside technological components when assessing readiness for sustainable digital health system development.
Body fat distribution, lipid profile and cardiometabolic risk factors in perimenopause Rosdiana Mus; Elpira Asmin; Ingrid Hutagalung; Mutmainnah Abbas; Genevieva Tanihatu; Jansye Cynthia Pentury
Media Penelitian dan Pengembangan Kesehatan Vol. 36 No. 3 (2026): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v36i3.4478

Abstract

Background: Body fat correlates with increased risks of metabolic and cardiovascular diseases, Young women are at a heightened risk for metabolic syndrome linked to dyslipidemia, which contributes to atherosclerosis. Objective: The aimed of study is correlation between body fat distribution, lipid profiles, and cardiometabolic risk factors in perimenopause women with age-specific Methods: A total of in 103 participants aged 35-55 years were included in this cross-sectional study with consecutive sample method. Participants were classified perimenopause women aged <45 and ≥45 years old. Body fat distribution used a Bioelectrical Impedance Analysis, Blood pressure used a sphygmomanometer and lipid profiles by lipid monitoring system by finger prick. Statistical analysis including independent sample t-tests, correlation analysis using pearson correlation test for normally and the Spearman correlation for non-normalyy distributed data.. Results: The results showed that there were differences in characteristics in two groups like WC (89.9±11.4 vs 96.1±9.8), systolic (132.7±23.3 vs 143±23.2), total cholesterol (170.5±39.8 vs 208.3±37.1), HDL-C (42.7±13.3 vs 50.69±14.8), LDL-C (105.7±28.1 vs 122.6±29.9) and TG (128.2±52.8 vs 170.6±74.9). Correlation analysis demonstrated positive correlation between of age with WC, systolic and lipid profiles. WC have a positive correlations with visceral fat and total fat, systolic and diastolic. Diastolic pressure positively correlated with total fat and visceral fat, with a strong correlation with systolic. Age,TC and TG correlated positively with WC and systolic, with LDL showing a similar correlation Conclusion: Research shows a significant association with several cardiovascular risk factors. These risk factors increases the risk of cardiovascular disease.
Research trends on critical thinking skills in Indonesian health journals: A methodological review Retno Heru Setyorini; Era Revika; Desi Ekawati
Media Penelitian dan Pengembangan Kesehatan Vol. 36 No. 3 (2026): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v36i3.4505

Abstract

Background: Critical thinking skills are essential in health education and practice, supporting evidence-based decision-making and health literacy. Although critical thinking research has increased globally, methodological analyses of Indonesian health journals remain limited. Objective: This study aimed to analyze publication trends and methodological characteristics of critical thinking skills research in Indonesian health journals. Methods: A methodological review using content analysis examined articles published between 2000 and 2025 in Indonesian health journals indexed in the Science and Technology Index (SINTA). Twenty-four eligible articles were analyzed based on seven aspects: publication year, research type and design, research subjects, health topics, interventions, data collection instruments, and data analysis methods. Results: Publications increased after 2019, with peaks in 2020 and 2024. Quantitative studies predominated (n=17; 70.8%), comprising quasi-experimental (n=9; 52.9%), cross-sectional (n=7; 41.2%), and cohort comparative (n=1; 5.9%) designs. Nursing students were the most frequently studied population. Only a limited number of studies addressed specific health issues, including reproductive health and urogenital disorders, while most focused on academic and psychological factors related to critical thinking. Questionnaires were the most commonly used instruments, and data analysis primarily relied on bivariate techniques, with limited use of multivariate analysis. Conclusion: This review provides a methodological overview of critical thinking skills research in Indonesian health journals, identifying dominant approaches and key methodological gaps. The findings may inform future research, particularly efforts to strengthen evidence-based health education research in Indonesia.
Digital reproductive health literacy and its implications for preventing adolescent pregnancy : a scoping review Maria Isabela Cardoso; Moh Hakimi; Andari Wuri Astuti
Media Penelitian dan Pengembangan Kesehatan Vol. 36 No. 3 (2026): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v36i3.4520

Abstract

Background: Adolescent pregnancy remains a public health concern affecting health, education and social life. Digital technology may expand adolescents’ access to reproductive health information; however, evidence on digital reproductive health literacy for pregnancy prevention remains limited, particularly in resource-constrained settings. Objective: To map evidence on digital reproductive health literacy, digital interventions and their implications for adolescent pregnancy prevention. Methods: This scoping review followed the Arksey and O’Malley framework and PRISMA-ScR guidelines. Searches were conducted in PubMed, ScienceDirect, Cochrane and Google Scholar for studies published from 2020-2025. Of the 600 records identified, 11 studies met the inclusion criteria. Data were analyzed using thematic synthesis. Results: Included studies were conducted in Africa, the United States and Brazil. Four themes were identified: adolescent sexual and reproductive health literacy; comprehensive sexuality education and educational interventions; digital technology for reproductive health education and access to services, policies and programs for adolescent pregnancy prevention. Two studies explicitly reported digital platforms: smartphone-based digital flashcards and web-based sexual health education. These approaches showed potential to improve access to and understanding reproductive health information, although the evidence remains limited. Conclusion: Digital reproductive health literacy may support adolescent pregnancy prevention as part of an integrated approach involving education, family, health services and policy. Further research should develop standardized measures and evaluate long-term behavioural and pregnancy-related outcomes, particularly in LMICs and resource-constrained settings.
Minimum inhibitory and bactericidal concentrations of Piper crocatum extract preparations against periodontopathogenic bacteria Herryawan Herryawan; Mutiara Yulina Putri; Rahmadaniah Khaerunnisa
Media Penelitian dan Pengembangan Kesehatan Vol. 36 No. 3 (2026): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v36i3.4559

Abstract

Background: Periodontitis is a chronic inflammatory disease associated with polymicrobial infection involving several representative periodontopathogenic bacteria. In selected clinical situations, adjunctive antimicrobial agents may be used to enhance mechanical treatment outcomes. Red betel leaf (Piper crocatum) has been traditionally recognized for its antibacterial properties and may serve as a plant-based alternative antimicrobial agent. Objective: This study aimed to determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of Piper crocatum extract preparations against representative periodontopathogenic bacteria. Methods: This in vitro experimental study evaluated the antibacterial activity of Piper crocatum extract preparations against Porphyromonas gingivalis, Treponema denticola, Fusobacterium nucleatum, and Aggregatibacter actinomycetemcomitans. Antibacterial testing was performed using the agar dilution method at extract concentrations of 0.78%, 1.56%, 3.12%, 6.25%, 12.5%, 25%, 50%, and 100% w/w. MIC was defined as the lowest concentration that prevented visible bacterial growth, while MBC was defined as the lowest concentration showing no bacterial growth following subculture. Results: The results showed concentration-dependent antibacterial activity against all tested bacteria. No visible bacterial growth (MIC) was first observed at 12.5% w/w, and complete absence of bacterial growth (MBC) was achieved at 25% w/w for all bacterial species. Conclusion: Piper crocatum extract preparations demonstrated antibacterial activity against the tested periodontopathogenic bacteria, supporting their potential for further development as a plant-based adjunctive antimicrobial formulation in periodontal therapy.
CDKN1A expression correlates with telomere length in skeletal muscle of d-galactose–induced rats Rita Dewi; Yoram Breslim; Maria Dara Novi Handayani; Ferbian Milas Siswanto
Media Penelitian dan Pengembangan Kesehatan Vol. 36 No. 3 (2026): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v36i3.4560

Abstract

Background: Telomere attrition and dysregulation of telomere-related genes, including telomerase reverse transcriptase (TERT) and telomeric repeat-binding factors (TERF1/TERF2), have been implicated in skeletal muscle aging. Telomere attrition may induce the expression of factors involved in senescence such as cyclin-dependent kinase inhibitor 1A (CDKN1A). Objective: This study aimed to determine the correlation of CDKN1A expression, telomere regulatory genes (TERT, TERF1, and TERF2), and telomere length in skeletal muscle of D-galactose-induced aging rats. Methods: This in vivo study included two groups of Wistar rats (n = 5 per group). The aging group was induced by D-galactose (300 mg/kg BW, i.p.), while the control group was treated with 0.9% NaCl (2 mL, i.p.) for 6 weeks. Gene expression levels were quantified using RT-qPCR, and telomere length was assessed using qPCR-based absolute telomere length assay. Results: CDKN1A expression was higher in the aging group compared to controls (p < 0.01), whereas TERT expression was lower (p < 0.05). No significant differences were observed in TERF1 and TERF2 expression between groups. Telomere length was significantly shortened in the aging group (p < 0.05). Correlation analysis revealed an inverse association between CDKN1A and TERT expression (R = -0.71; p < 0.05). No significant correlations were found between CDKN1A and TERF1 or TERF2 (p > 0.05). In addition, CDKN1A expression was inversely correlated with telomere length (R = -0.9; p < 0.05). Conclusion: CDKN1A is inversely associated with TERT expression and telomere length in D-galactose–induced aging, suggesting a coordinated role in skeletal muscle aging.
Holistic nursing care, quality of life, and self-efficacy in type 2 diabetes mellitus patients: a cross-sectional study Nurul Jannah; Anas Kiki Anugrah; Supriadin Supriadin; Dian Apri Nelyanti; Sri Rahayu
Media Penelitian dan Pengembangan Kesehatan Vol. 36 No. 3 (2026): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v36i3.4574

Abstract

Background: Diabetes mellitus is a chronic disease affecting various dimensions of patients’ health, including physical, psychological, social, and spiritual aspects. Holistic nursing care has been associated with self-efficacy and quality of life; however, evidence regarding these associations remains limited. Objective:  This study aimed to examine the association between holistic nursing care, self-efficacy, and quality of life among patients with type 2 diabetes mellitus. Methods: A quantitative cross-sectional study was conducted among 100 patients with type 2 diabetes mellitus recruited using purposive sampling. Data were collected through structured questionnaires assessing holistic nursing care, self-efficacy, and quality of life. Pearson’s correlation and multiple linear regression analyses were performed to examine the associations among study variables. Results: Holistic nursing care was positively associated with self-efficacy (r = 0.356; p = 0.001) and quality of life (r = 0.382; p = 0.001). Regression analysis showed that holistic nursing care remained significantly associated with self-efficacy (R² = 0.186; Adjusted R² = 0.124; B = 0.164; β = 0.296; p = 0.004) and quality of life (R² = 0.184; Adjusted R² = 0.122; B = 0.268; β = 0.395; p = 0.001). Sex, age, blood glucose level, medication adherence, healthcare visit frequency, and diabetes education history were not significantly associated with self-efficacy or quality of life (p > 0.05). Conclusion: Holistic nursing care was significantly associated with self-efficacy and quality of life among patients with type 2 diabetes mellitus. Longitudinal studies are needed to further explore temporal relationships between holistic nursing care and patient outcomes.
Sociocultural family determinants and secondhand smoke exposure with respiratory disorders, stunting in children: Scoping review Pascoela da Costa de Jesus Xavier; Dewi Rokhanawati; Ismarwati Ismarwati
Media Penelitian dan Pengembangan Kesehatan Vol. 36 No. 3 (2026): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v36i3.4603

Abstract

Background: Exposure to cigarette smoke indoors remains a concern among children in developing countries. Smoking poses serious health risks to children, as no safe level of secondhand smoke exposure exists. Family sociocultural determinants play a crucial role in shaping household smoking behaviors, thereby influencing children’s respiratory health and nutritional status. However, evidence remains fragmented and incomprehensively mapped. Objective: This study aimed to map evidence on family sociocultural determinants of household tobacco smoke exposure and their association with respiratory disorders and stunting among children aged 0–59 months in developing countries. Methods: This scoping review searched PubMed, ScienceDirect, Wiley Online Library, and Google Scholar for original studies published in English between 2015 and 2025 in developing countries. Eligible studies involved children aged 0–59 months or their caregivers/households exposed to cigarette smoke and examined family sociocultural determinants of smoking related to respiratory and nutritional outcomes. Irrelevant studies were excluded, and data were descriptively analyzed. Results: Eleven articles were included: 10 country-specific and 1 multi-country study, representing 9 unique countries. Country-specific studies were from India (4), Indonesia (2), South Africa (1), Albania (1), Malaysia (1), and Turkey (1), while the multi-country study included Cambodia, Indonesia, Lao PDR, and Timor-Leste. Studies showed that family sociocultural determinants influence children's exposure to secondhand smoke and increase the risk of respiratory disorders and stunting. Evidence on family-based interventions remains limited. Conclusion: Family sociocultural determinants shape tobacco smoke exposure and its adverse effects on children’s respiratory and nutritional health. These findings support culturally appropriate health promotion strategies and community midwifery policies.
Nutrient intake and sleep quality are associated with serum FSH levels in perimenopausal women: A cross-sectional study May Kristina Indah K Telaumbanua; Linda Ratna Wati; Bambang Rahardjo; Lilik Indahwati; Krisjentha Iffah Agustasari; Imam Mashuda
Media Penelitian dan Pengembangan Kesehatan Vol. 36 No. 3 (2026): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v36i3.4645

Abstract

Background: Hormonal fluctuations during the perimenopausal phase due to decreased ovarian function are influenced by various factors, including nutrient intake and sleep quality, which are thought to play a role in hormonal regulation. Objective: This study aimed to evaluate the relationships between macronutrient and micronutrient intake, sleep quality, and serum FSH levels in Indonesian perimenopausal women. Methods: This study used an analytical observational design with a cross-sectional approach involving 120 perimenopausal women in Gondanglegi, Malang, from September to November 2025. The sample was selected by cluster random sampling. Nutrient intake data were collected with multiple 24-hour food recalls, sleep quality was measured using the Pittsburgh Sleep Quality Index (PSQI), and serum follicle-stimulating hormone (FSH) levels were assessed with ELISA. Data analysis was performed using the Spearman correlation test and multiple linear regression (α = 0.05). Results: The mean serum FSH level was 16.73 ± 18.48 IU/L. Bivariate analysis showed a significant correlation between fat intake (r=-0.348; p<0.001), protein (r=0.304; p=0.001), iron (r=0.298; p=0.001), zinc (r=0.297; p=0.001), sleep quality (r=-0.304; p=0.001) and serum FSH levels. Meanwhile, carbohydrate intake was not significant (p=0.535). Multiple linear regression analysis showed that all independent variables accounted for 22.2% of the variation in FSH levels (R²=0.222; p<0.001), with fat intake, carbohydrate intake, iron intake, and sleep quality as predictors. Conclusion: Fat, carbohydrate, and iron intake, along with sleep quality, were independently associated with serum FSH levels in perimenopausal women, highlighting their role in hormonal variation during the menopausal transition.

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