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Jurnal Sains dan Kesehatan
Published by Universitas Mulawarman
ISSN : 23030267     EISSN : 24076082     DOI : 10.25026/jsk
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
Jurnal Sains dan Kesehatan menerima naskah karya asli (Artikel Penelitian, Artikel Review, dan Studi Kasus), baik eksperimental maupun teoretis, dalam bidang-bidang berikut: Sains dan Kesehatan (Kedokteran, Farmasi, Kesehatan Masyarakat, Keperawatan, Kebidanan, Gizi, dan lain-lain). Tujuan penerbitan Jurnal Sains dan Kesehatan adalah untuk menyediakan informasi ilmiah tentang perkembangan ilmu dan teknologi di bidang Ilmu Pengetahuan dan Kesehatan.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 764 Documents
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Ureum and Creatinine Levels of Kidney Failure Patients Pra and Post Hemodialysis in Jayapura General Hospital Papua Herlando Sinaga; Rini Prastyawati; Rivie Joan Pretty Tompodung; Beby Syahputra Surbakti; Sulistianingsih Sulistianingsih
Jurnal Sains dan Kesehatan Vol. 5 No. 4 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i4.1586

Abstract

Kidney failure is a worldwide health problem seen from the increase in incidence, prevalence, and the level of morbidity. Indonesia is one country with high rates of kidney failure. The purpose of this research was to determine the description of the results of urea and creatinine levels in patients with kidney failure before and after hemodialysis. The population used in this study was all renal failure patients who would carry out hemodialysis at the Jayapura Regional General Hospital (RSUD). The number of samples in this research is 30. The method of examining urea and creatinine used is the photometry method. This research was conducted from 10 May to 10 June 2018. To determine the levels of urea and creatinine before and after hemodialysis, the average value of the results of the examination was calculated and the results of the average urea level before hemodialysis 53.37 mg/dl and the average yield were obtained. Average after hemodialysis 18.83 mg/dl. The results of the average creatinine level of patients before 12.25 mg/dl and the average results after hemodialysis were 43.63 mg/dl. The results of the examination showed that there were no significant differences and that the results remained high. This research concluded that there was no significant difference between the examination of urea and creatinine levels before hemodialysis and after hemodialysis.
Kajian Praklinis Ekstrak Etanol Herba Tridax procumbens (Linn.) sebagai Antidiabetik pada Tikus Putih Diabetes (Rattus norvegicus) yang Diinduksi Streptozotosin: Preclinical Study of Ethanol Extract of Herba Tridax procumbens (Linn.) as Antidiabetic in Streptozotocin-Induced Diabetic White Rats (Rattus norvegicus) Syaiful Katadi; Irman Idrus; Arman Rusman; Sitti Sarfila
Jurnal Sains dan Kesehatan Vol. 5 No. 1 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i1.1597

Abstract

This study aims to conduct a preclinical study of the antidiabetic effect of the ethanol extract of the herb Tridax procumbens (Asteraceae) in streptozotocin-induced diabetic rats. The research procedure began by collecting test samples of the Tridax procumbens Linn (TP) herb. All parts of the TP plant which were air-dried were extracted with ethanol (95%) by maceration for 72 hours, then phytochemical screening was carried out to determine the content of secondary metabolites in general. The antidiabetic test was initiated by inducing male Wistar rats with streptozotocin (50 mg/jk, i.p.) and nicotinamide (120 mg/kg, i.p.) by injection. Diabetic rats were treated with glibenclamide (0.25 mg/kg, po) and TP extract (250 and 500 mg/kg, p.o.) for 21 consecutive days. Blood samples were collected periodically to measure the hypoglycemic effect of the TP extract. Then, variations in body weight at the fair were monitored for all experimental animals. The results showed that TP extract had a significant antidiabetic effect on diabetic white rats (Rattus norvegicus), with the best results given TP extract at a dose of 500 mg/kg. Keywords: Tridax procumbens, diabetes mellitus, antidiabetic Abstrak Penelitian ini bertujuan untuk melakukan kajian praklinis efek antidiabetes dari ekstrak etanol herba Tridax procumbens (Asteraceae) pada tikus diabetes yang diinduksi streptozotocin. Prosedur penelitian dimulai dengan mengumpulkan sampel uji herba Tridax procumbens Linn (TP). Seluruh bagian tanaman TP yang telah dikeringkan diekstraksi dengan etanol (95%) dengan cara dimaserasi selama 72 jam, selanjutnya dilakukan skrining fitokimia untuk mengetahui kandungan metabolit sekundernya secara umum. Untuk Uji antidiabetes dimulai dengan menginduksi tikus Wistar jantan dengan streptozotocin (50 mg/kg, ip) dan nicotinamide (120 mg/kg, ip). Tikus diabetes diobati dengan glibenklamid (0,25 mg/kg, po) dan ekstrak TP (250 dan 500 mg/kg, p.o.) selama 21 hari berturut-turut. Sampel darah dikumpulkan secara berkala untuk mengukur efek hipoglikemik ektrak TP. Kemudian, variasi berat badan mingguan dipantau untuk semua hewan percobaan. Hasil penelitian menunjukkan ekstrak TP memiliki efek antidiabetik yang signifikan terhadap tikus putih diabetes (Rattus norvegicus), dengan hasil terbaik pada pemberian ekstrak TP dosis 500 mg/KgBB. Kata Kunci: Tridax procumbens, diabetes mellitus, antidiabetik
Study of Antioxidant Activity, Total Phenolic Content (TPC), and Total Flavonoid Content (TFC) of Ethanolic Extract Mango Peel (Mangifera indica L.) Wigati, Dyan; Pratoko, Dwi Koko
Jurnal Sains dan Kesehatan Vol. 6 No. 1 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i1.1601

Abstract

Mango is one of the fruits rich in phenols and flavonoids, proven to have the ability to scavenge free radicals. The level of compounds in the sample can influence antioxidant capacity, including the total phenolic and flavonoid content. Peel of mango is a non-edible waste. This study aims to determine the total phenolic and flavonoid content and antioxidant activity of mango peel variety arum Manis, extracted by percolation using 70% ethanol. The total phenolic content was measured using Folin-Ciocalteu method, and flavonoid content was measured using AlCl3. The absorbances were measured using UV-Vis spectrophotometry. The DPPH radical scavenging assay to assess antioxidant activity. The result reveals that the mango peel's ethanol extract had a total phenolic content of 19.31±0.41 mgGAE/g extract, a total flavonoid content of 22.06±1.74 mgQE/g extract, and an IC50 value of 766.444 ppm. This research showed that mango peel's antioxidant activity is weak compared to standard vitamin C (6.414 ppm). This is possibly due to the low level of metabolite content, including complexities of the phenolic and flavonoid types in the extract.
Pemanfaatan Limbah Pati Kulit Pisang (Musa paradisiaca) sebagai Bahan Pengikat Granul Parasetamol dengan Metode Granulasi Basah: Utilization of Waste Banana Peel Starch (Musa paradisiaca) as a Binder Material for Paracetamol Granules Using Wet Granulation Method Ingwe Violenneofita Cheiya; Rolan Rusli; Nurul Fitriani
Jurnal Sains dan Kesehatan Vol. 5 No. 1 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i1.1606

Abstract

Starch is a carbohydrate that can be used as a binder in pharmaceutical preparations. Paracetamol has poor flowability and compactibility with its crystalline form, it is necessary to make granules by wet granulation method with starch as a binder. This study used banana peel waste (Musa paradisiaca) as a source of starch. Three granule formulations (F1, F2, and F3) were prepared using the wet granulation method with banana peel waste starch as a binder with concentrations of 5% (F1), 8% (F2), and 10% (F3) w/v. The results showed that the granule quality test included testing of moisture content, flow rate, angle of repose, and compressibility index, with the results of the granule moisture content test being 3.52%, granule flow rate 4.8 seconds, angle of repose 37.7°, and index compressibility of 10% meets the parameters of a good granule preparation. Keywords: Granule, Kepok banana peel, Starch, Paracetamol Abstrak Pati atau amilum merupakan karbohidrat yang dapat digunakan sebagai bahan pengikat pada sediaan farmasi. Parasetamol memiliki sifat alir dan kompaktibilitas yang buruk dengan bentuknya yang kristal, maka perlu dibuat granul dengan metode granulasi basah dengan pati sebagai pengikatnya. Penelitian ini menggunakan limbah kulit pisang (Musa paradisiaca) sebagai sumber pati. Tiga formula sediaan granul (F1, F2, dan F3) dibuat menggunakan metode granulasi basah dengan pati limbah kulit buah pisang sebagai pengikat dengan konsentrasi 5% (F1), 8% (F2), dan 10% (F3) b/v. Hasil penelitian menunjukan bahwa uji kualitas granul meliputi pengujian kadar lembab, laju alir, sudut diam, dan indeks kompresibilitas, dengan hasil uji kadar lembab granul 3,52%, laju alir granul 4,8 detik, sudut diam 37,7°, dan indeks kompresibilitas 10% memenuhi parameter sediaan granul yang baik. Kata Kunci: Granul, Kulit buah pisang kepok, Pati, Parasetamol
Pengaruh Ekstrak Etanol Daun Asam Jawa (Tamarindus indica L.) terhadap Jantung Tikus Putih (Rattus norvegicus L.) yang Diinduksi Minyak Jelantah: Effect of Java Acid Leaf (Tamarindus indica L.) Ethanol Extract on Heart of White Rats (Rattus norvegicus L.) Induced Used Cooking Oil Nurkhaida Siregar; Husnarika Febriani; Syukriah Syukriah
Jurnal Sains dan Kesehatan Vol. 5 No. 2 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i2.1619

Abstract

This study aims to determine the effect of ethanol tamarind leaves (Tamarindus indica L.) om histology and levels of the enzyme lactate dehydrogenase (LDH) in rat hearts induced by used cooking oil.This study used a completely randomized design with 25 male white rats devided into 5 groups: negetive control, positive control, 1, 2 and 3 doses treatment (150 mg/kg BW, 200 mg/kg BW, and 250 mg/kg BW), where each group consisted of 5 replications. The stages of this research were phytochemical screening, total flavonoid test, antioxidant test, oil quality test, measurement of lactate dehydrogenase (LDH) enzyme levels and cardiac histological observations. The data analysis used was one way ANOVA followed by Duncan’s test. The results showed that the dose of ethanol extract of tamarind leaves (Tamarindus indica L.) 250 mg/kg BW was the most optimal dose to reduce histological damage in the form of pycnotic percentage with an average of 30.40% and thickness of the myocardium of the heart with an average of 852.8 um and decreased cardiac lactate dehydrogenase (LDH) levels by an average of 152 U/L. The ethanol extract of tamarind leaves (Tamarindus indica L.) had an effect on the hearts of white rats (Rattus norvegicus L.) induced by used cooking oil. Keywords: Used Cooking Oil, Tamarindus indica, Heart Abstrak Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak etanol daun asam jawa (Tamarindus indica L.) terhadap histologi dan kadar enzim lactat dehidrogenase (LDH) jantung tikus yang diinduksi minyak jelantah. Penelitian ini menggunakan rancangan acak lengkap dengan 25 tikus putih jantan yang dibagi 5 kelompok yaitu kelompok kontrol negatif, kontrol positif, perlakuan 1, 2 dan 3 dosis (150 mg/kg BB, 200 mg/kg BB, dan 250 mg/kg BB), dimana masing-masing kelompok terdiri dari 5 ulangan. Tahapan penelitian ini adalah skrining fitokimia, uji flavonoid total, uji antioksidan, uji kualitas minyak, pengukuran kadar enzim lactat dehidrogenase (LDH) dan pengamatan histologi jantung. Analisis data yang digunakan adalah one way ANOVA dilanjutkan dengan uji Duncan. Hasil penelitian menunjukkan bahwa dosis ekstrak etanol daun asam jawa (Tamarindus indica L.) 250 mg/kg BB merupakan dosis paling optimal menurunkan kerusakan histologi berupa persentase piknotik dengan rata-rata 30,40 % dan ketebalan miokardium jantung dengan rata-rata 852,8 um serta menurunkan kadar enzim lactat dehidrogenase (LDH) jantung dengan rata-rata 152 U/L. Ekstrak etanol daun asam jawa (Tamarindus indica L.) berpengaruh terhadap jantung tikus putih (Rattus norvegicus L.) yang diinduksi minyak jelantah. Kata Kunci: Minyak Jelantah, Tamarindus indica, Jantung
Analisis Kandungan Natrium Siklamat pada Jamu Sinom di Pasar Besar Malang: Analysis of Sodium Cyclamate Content in Jamu Sinom at Malang Market Fendi Yoga Wardana; Vita Mariah
Jurnal Sains dan Kesehatan Vol. 5 No. 5 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i5.1620

Abstract

Jamu is a traditional medicine used by people in Indonesia. The use of additional sweeteners such as sodium cyclamate needs to be wary of its use, because it can cause harmful effects to the body in the future. The herbs that have been circulating in the community are allegedly added with additional sweeteners during the manufacturing process. The aim of this study was to determine the content of sodium cyclamate in jamu sinom at Pasar Besar Malang. The design of this study was an experimental laboratory with purposive sampling on 6 samples of jamu sinom. Qualitative analysis was tested by precipitation method, while quantitative analysis was performed by spectrophotometry UV-Vis. The results of the qualitative test showed that there were 2 positive samples containing sodium cyclamate, namely sample B and sample D which were marked by the formation of a white precipitate. Based on the results of the quantitative test with spectrophotometry UV-Vis, it was found that 2 samples did not comply with BPOM standards with sodium cyclamate levels of 5.053% in sample B and 1.959% in sample D. Keywords: Jamu, Sodium Cyclamate, Precipitation, Spectrophotometry UV-Vis Abstrak Jamu merupakan obat tradisional yang banyak dimanfaatkan oleh masyarakat di Indonesia. Penggunaan bahan pemanis buatan seperti natrium siklamat perlu diwaspadai penggunaannya, karena dapat menimbulkan efek yang berbahaya bagi tubuh dikemudian hari. Jamu yang telah beredar di masyarakat disinyalir ditambahkan pemanis buatan saat proses pembuatannya. Tujuan penelitian adalah mengetahui kandungan natrium siklamat dalam jamu sinom yang dipasarkan di Pasar Besar Malang. Desain penelitian ini adalah laboratorium eksperimental dengan teknik purposive sampling pada 6 jenis sampel jamu sinom. Pengujian analisa kualitatif dilakukan dengan metode pengendapan, sedangkan analisa kuantitatif dilakukan dengan spektrofotometri UV-Vis. Hasil uji kualitatif menunjukkan terdapat 2 sampel positif mengandung natrium siklamat yaitu sampel B dan sampel D yang ditandai dengan terbentuknya endapan berwarna putih. Berdasarkan hasil uji kuantitatif dengan spektrofotometri UV-Vis, didapatkan 2 sampel tidak memenuhi standar BPOM dengan kadar natrium siklamat sebesar 5,053% pada sampel B dan 1,959% pada sampel D. Kata Kunci: Jamu, Natrium Siklamat, Pengendapan, Spektrofotometri UV-Vis.
Aktivitas Ekstrak Metanol Daun Alang-Alang (Imperata cylindrica (L.) P. Beauv) sebagai Antinflamasi: Activity of Alang-Alang (Imperata cylindrica (L.) P. Beauv) Leaves Methanol Extract as Anti-inflammatory Chairul Saleh; Marem Sestiani; Erwin Erwin
Jurnal Sains dan Kesehatan Vol. 5 No. 3 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i3.1649

Abstract

An anti-inflammatory activity test of methanol extract of alang-alang leaves (Imperata cylindrica (L.) P. Beauv) on protein denaturation inhibition in vitro was carried out. The purpose of this study was to determine the content of secondary metabolites and the anti-inflammatory activity of the methanol extract of alang-alang leaves. The method used is a qualitative test method based on staining to determine the content of secondary metabolites and an in vitro method using a protein in the form of Bovine serum albumin (BSA) which is induced by heat to determine the anti-inflammatory activity of methanol extract of Imperata leaves and diclofenac sodium as a positive control. results of the phytochemical screening showed that the methanol extract of Imperata leaves contained flavonoids, phenolics and steroids. Activity test of alang-alang leaf methanol extract in IC50 was 125.937 ppm. The methanol extract of alang-alang leaves has potential as an anti-inflammatory. Keywords: Imperata cylindrica (L.) P. Beauv, Alang-alang, Anti-inflammatory, In Vitro AbstrakUji aktivitas antiinflamasi ekstrak metanol daun alang-alang (Imperata cylindrica (L.) P. Beauv) terhadap penghambatan denturasi protein secara in vitro telah dilakukan. Tujuan penelitian ini adalah untuk menentukan kandungan senyawa metabolit sekunder dan aktivitas antiinflamasi ekstrak metanol daun alang-alang. Metode yang digunakan ialah metode uji kualitatif berdasarkan perwarnaan untuk menentukan kandungan metabolit sekunder dan metode in vitro menggunakan protein berupa Bovine serum albumin (BSA) yang diinduksi oleh panas untuk menentukan aktivitas antiinflamasi ekstrak metanol daun Alang-alang dan natrium diklofenak sebagai control positif. Hasil skrining fitokimia menunjukkan ekstrak metanol daun alang-alang mengandung flavonoid, fenolik dan steroid. Uji aktivitas ekstrak metanol daun alang-alang dalam IC50 adalah 125,937 ppm. Ekstrak metanol daun alang-alang memiliki potensi sebagai antiinflamasi. Kata Kunci: Imperata cylindrica (L.) P. Beauv, Alang-alang, Antiinflamasi, In Vitro
Hand Sanitizer Ekstrak Etanol Daun Simpur (Dillenia suffruticosa) sebagai Antiseptik Bakteri Escherechia coli dan Staphilococcus aureus: Simpur Leaf Ethanol Extract Hand Sanitizer as Bacterial Antiseptic to Escherichia coli and Staphilococcus aureus Ririn Putri Fania; Masriani Masriani; Dewi Setiya Ningsih; Heni Erliani
Jurnal Sains dan Kesehatan Vol. 5 No. 3 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i3.1655

Abstract

Infectious diseases ranks third of the ten highest disease-causing diseases in Indonesia. Hand washing with hand sanitizer is the most important basic technique in the prevention and control of transmission of infectious diseases. The study of Hand sanitizer ethanol extract of simpur (Dillenia suffruticosa) leaves as an antiseptic to Eschericia coli and Staphylococcus aureus was conducted. Research on the objective of this study are to determine activity and effectiveness of ethanol extract of simpur leaves and stability gel preparation of hand sanitizer. The result of phytochemical tests showed that simpur leaves contains flavonoid, alkaloids, terpenoids, phenols, and saponins compounds. Examination of antibacterial activity and effectivity of ethanol extract of simpur leaves using paper diffusion method using Muller Hinon Agar (MHA) media with 3 replication showed good result on three concentrations are F1 (5%); F2 (7.5%); and F3 (10%). The largest inhibitory zone found in gel hand sanitizers containing the largest extract concentrations of F3 (10%) yielded an average drag zone of 9.87 mm in Escherichia coli and 7.15 mm in Staphylococsus aureus. Simpur leaf extract as an active ingredient proved effective as an antiseptic to inhibit or kill bacteria.The results of this study indicate that the hand sanitizer from simpur ethanol extract has the potential to be used as an antiseptic. Keywords: Dillenis suffruticosa; hand sanitizer; antiseptic; E. coli; S. aureus Abstrak Penyakit infeksi menempati urutan ketiga dari sepuluh penyakit penyebab kematian tertinggi di Indonesia. Cuci tangan menggunakan hand sanitizer merupakan teknik dasar yang paling penting dalam pencegahan dan pengontrolan penularan penyakit infeksi. Penelitian tentang Hand sanitizer ekstrak etanol daun simpur (Dillenia suffruticosa) sebagai antiseptik terhadap bakteri Eschericia coli dan Staphylococcus aureus telah dilakukan. Tujuan dari penelitian ini adalah untuk menentukan senyawa fitokimia, aktivitas, dan stabilitas sediaan gel hand sanitizer ekstrak etanol daun simpur. Hasil skrining fitokimia menunjukkan bahwa daun simpur positif mengandung senyawa flavonoid, alkaloid, terpenoid, fenol, dan saponin. Pengujian antibakteri ekstrak etanol daun simpur menggunakan metode difusi kertas cakram menggunakan media Muller Hinon Agar (MHA) dengan 3 replikasi menunjukkan hasil yang baik pada tiga konsentrasi yaitu F1 (5%); F2 (7,5%); dan F3 (10%). Zona hambat terbesar terdapat pada gel hand sanitizer yang mengandung konsentrasi ekstrak terbesar yaitu pada F3 (10%) menghasilkan rata-rata zona hambat sebesar 9,87 mm pada E. coli dan 7,15 mm pada S. aureus. Ekstrak daun simpur sebagai bahan aktif terbukti efektif sebagai antiseptik untuk menghambat atau membunuh bakteri. Hasil penelitian ini mengindikasikan bahwa hand sanitizer dari ekstrak etanol daun simpur berpotensi digunakan sebagai antiseptik. Kata Kunci: Dillenia suffruticosa; hand sanitizer; antiseptik; E. Coli; S. aureus
Karakterisasi Pati Bonggol Pisang Kepok Kuning (Musa paradisiaca L.) sebagai Bahan Tambahan Sediaan Farmasi: Characterization of Sucker Starch of Yellow Kepok Banana (Musa paradisiaca L.) as Pharmaceutical Excipient Tias Eka Rahmawati; Intan Martha Cahyani; Siti Munisih
Jurnal Sains dan Kesehatan Vol. 5 No. 2 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i2.1658

Abstract

Banana sucker is the part of banana plant which is rarely used and is considered trash after harvesting. The banana sucker composition is 76% starch and 20% water. Starch content in banana sucker has the potential to developed in the pharmaceutical industry. The aim of this study was to find a new source of starch and determine the characterization of starch sucker of yellow kepok  banana as an alternative excipient in pharmaceutical. The sucker starch of yellow kepok banna isolation uses bleaching method whith sulfite solution. Results showed that sucker starch of yellow kepok banan from Plamongansari and Ambarawa powder form, brownish white, odorless, and tasteless. Kepok banana sucker strach has a pH of 6.51 and 6.60; moisture content 11.74% and 13.29%; ash content 0.74% - 0.83%; moisture content 12.28% and 13.50%; flow rate of 0.86 grams/second and 1.04 grams/second; resting angle 39.89° and 39.91° so that banana sucker starch includes a fairly good flow properties; development power 80.36% and 93.65%; solubility 18.28% and 22.96%; particle size 32.984 μm – 91.466μm, starch content 45.07% and 51.48%.. Starch producted further characterized using FT-IR to know functional groups is OH, C-H, C-O-C and C-O which is the same as the chemical structure of starch. Keywords: banana sucker, characterization, starch Abstrak Bonggol pisang merupakan bagian bawah tanaman pisang yang jarang dimanfaatkan dan dianggap sampah setelah pemanenan buah pisang. Komposisi bonggol pisang meliputi 76% pati, 20% air. Kandungan pati yang tinggi dalam bonggol pisang berpotensi untuk dikembangkan dalam industri farmasi sebagai bahan penghancur, pengisi, dan pengikat. Tujuan dari penelitian ini adalah mencari sumber pati baru dan mengetahui karakterisasi pati bonggol pisang kepok kuning (Musa paradisiaca L.) sebagai alternatif bahan tambahan dalam sediaan farmasi. Metode isolasi pati bonggol pisang kepok kuning menggunakan metode bleaching dengan larutan bisulfit. Hasil penelitian uji karakterisasi pati bonggol pisang kepok kuning daerah Plamongansari dan Ambarawa putih kecoklatan, tidak berbau, dan tidak berasa. Pati bonggol pisang kepok kuning memiliki pH 6,51 dan 6,60; kadar air 11,74% dan 13,29%; kadar abu 0,74% dan 0,83%; kandungan lembap 12,28% dan13,50%; kecepatan alir 0,86 gram/detik dan 1,04 gram/detik; sudut istirahat 39,91° dan 39,89° sehingga pati bonggol pisang termasuk memiliki sifat alir yang cukup baik; daya pengembangan 80,36% dan 93,65%; kelarutan 18,28% dan 22,96%; ukuran partikel 32.984μm – 91.466μm, kadar pati 45,07% dan 51,48%. Pati yang dihasilkan selanjutnya di karakteristik gugus fungsinya dengan menggunakan FTIR terdapat gugus OH, C-H, C-O-C dan C-O yang sama dengan struktur kimia amilum. Kata Kunci: bonggol pisang, karakterisasi, pati
Front Cover, Editorial Information, Table of Content, Author Guideline, Back Cover Journal Editor
Jurnal Sains dan Kesehatan Vol. 4 No. 6 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i6.1662

Abstract

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