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JOURNAL OF Pharmacy and Tropical Issues
Published by Indonesian Public Health-Observer Information Forum
ISSN : 28074319     EISSN : 28074122     DOI : https://doi.org/10.56922/pti.v4i2
Core Subject : Health,
Medicine & Pharmacology
Jurnal penelitian dibidang kesehatan meliputi ilmu keparmasian. Penelitain sesuai tren pengobatan sesuai sumber alam di negara tropis. Pengembangan obat dan pendistribusian kepada pelanggan, dan sesuai aturan Badan Pengawas Obat dan Makanan (BPOM) - Republik Indonesia
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 53 Documents
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Evaluasi efektivitas fotokatalis zno/biochar terhadap degradasi antibiotik tetrasiklin menggunakan spektrofotometri uv-vis Husein, Saddam; Setiawan, Fatma Aris; Alkausar, Radho
JOURNAL OF Pharmacy and Tropical Issues Vol. 6 No. 1 (2026): May Edition 2026
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR) Kerjasama dengan Ikatan Sarjana Farmasi Indonesia (ISFI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/pti.v6i1.3046

Abstract

Background: Tetracycline contamination in aquatic environments has become a serious issue due to its persistence and resistance to conventional degradation methods. Photocatalysis using ZnO/Biochar composite is an Advanced Oxidation Process (AOP) capable of degrading complex organic compounds through reactive radical formation. Purpose: To evaluate the effectiveness of ZnO/Biochar photocatalyst in degrading tetracycline based on catalyst dosage and irradiation time under UV-Vis light. Method: This experimental laboratory study used UV-Vis spectrophotometry at a maximum wavelength of 378 nm. Results: The 0.5 g dosage showed the highest degradation efficiency of 84% at 120 minutes. Increasing catalyst dosage up to 0.5 g improved degradation, while 1 g reduced efficiency due to increased turbidity. Degradation increased with irradiation time. The reaction followed pseudo-first-order kinetics with a rate constant of 0.0142 min⁻¹. Conclusion:  ZnO/Biochar effectively degrades tetracycline under UV-Vis irradiation, with optimal performance at 0.5 g catalyst dosage following pseudo-first-order kinetics.   Keywords: Photocatalysis; Tetracycline; UV-Vis; ZnO/Biochar.   Pendahuluan: Pencemaran antibiotik tetrasiklin di perairan menjadi permasalahan lingkungan karena sifatnya yang persisten dan sulit terdegradasi secara konvensional. Fotokatalisis menggunakan komposit ZnO/Biochar merupakan metode Advanced Oxidation Processes (AOPs) yang efektif dalam mendegradasi senyawa organik melalui pembentukan radikal reaktif. Tujuan: Mengetahui efektivitas fotokatalis ZnO/Biochar dalam mendegradasi tetrasiklin berdasarkan variasi dosis katalis dan waktu iradiasi menggunakan lampu UV-Vis. Metode: Penelitian eksperimental laboratorium menggunakan spektrofotometri UV-Vis pada panjang gelombang 378 nm. Hasil: Dosis 0,5 g menunjukkan degradasi tertinggi sebesar 84% pada menit ke-120. Peningkatan dosis hingga 0,5 g meningkatkan efisiensi, sedangkan pada 1 g terjadi penurunan akibat kekeruhan larutan. Degradasi meningkat seiring waktu iradiasi. Kinetika reaksi mengikuti orde satu semu dengan konstanta laju 0,0142 menit⁻¹. Simpulan: ZnO/Biochar efektif mendegradasi tetrasiklin dengan kondisi optimum pada dosis 0,5 g dan penyinaran UV-Vis, serta mengikuti kinetika orde satu semu.
Evaluasi penggunaan obat golongan statin pada pasien hiperlipidemia Meithia, Artha; Zatara, Tubagus Puspa; Angin, Martianus Perangin; Wijaya, Satria
JOURNAL OF Pharmacy and Tropical Issues Vol. 6 No. 1 (2026): May Edition 2026
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR) Kerjasama dengan Ikatan Sarjana Farmasi Indonesia (ISFI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/pti.v6i1.3132

Abstract

Beground: Hyperlipidemia is a condition characterized by high concentrations of lipids, cholesterol, and triglycerides in the blood. Hyperlipidemia is one of the most serious and deadly diseases worldwide. Purpose: To evaluate the use of statin drugs in hyperlipidemia patients with the criteria of correct diagnosis, correct patient, correct indication, correct drug, correct dose, and correct method of administration. Method: This study used descriptive qualitative research, utilizing primary medical record data, considering inclusion and exclusion criteria. Sampling was conducted using a purposive sampling method. The study was conducted at Imanuel Way Halim Hospital in Bandar Lampung and has received research ethics approval No. 4397/EC/KEP-UNMAL/VI/2024. Result: Based on the calculation, the criteria obtained were 100% correct diagnosis, 100% correct patient, 100% correct indication, 100% correct drug, 100% correct dose, 100% correct method of administration, and 100% correct time of administration. The most commonly used hyperlipidemia drug was simvastatin 20 mg with a percentage of 30.77%. In addition, the characteristics of patients based on age were the most common, namely 55-65 years old with a percentage of 32.69%, based on gender, namely women with a percentage of 53.85%, and based on comorbidities, namely hypertension with a percentage of 31.37%. Conclusion: The use of statin drugs in patients with hyperlipidemia is rational. The most commonly used hyperlipidemia medication is simvastatin 20 mg.   Keywords: Drug Use Evaluation; Hyperlipidemia; Statin.   Pendahuluan: Hiperlipidemia merupakan penyakit yang mengacu pada konsentrasi tinggi dari lipid, kolesterol, dan trigliserida dalam darah. Penyakit hiperlipidemia termasuk salah satu penyakit serius serta mematikan di dunia. Tujuan: Untuk mengevaluasi penggunaan obat golongan statin pada pasien hiperlipidemia dengan kriteria tepat diagnosa, tepat pasien, tepat indikasi, tepat obat, tepat dosis, dan tepat cara pemberian. Metode: Menggunakan jenis penelitian kualitatif deskriptif yang dilakukan dengan menggunakan data primer rekam medik yang mempertimbangkan kriteria inklusi dan eksklusi. Pengambilan sampel dilakukan dengan metode purposive sampling. Penelitian yang dilakukan di Rumah Sakit Imanuel Way Halim Bandar Lampung dan sudah mendapat perizinan etik penelitian No.4397/EC/KEP-UNMAL/VI/2024. Hasil: Berdasarkan perhitungan diperoleh kriteria tepat diagnosa 100%, tepat pasien 100%, tepat indikasi 100%, tepat obat 100%, tepat dosis 100%, tepat cara pemberian 100%, tepat waktu pemberian 100%. Penggunaan obat hiperlipidemia yang banyak digunakan yaitu simvastatin 20 mg dengan persentase 30.77%. Selain itu, karakteristik pasien berdasarkan usia yang paling banyak yaitu usia 55-65 tahun persentase 32.69%, berdasarkan jenis kelamin yaitu perempuan dengan persentase 53.85%, dan berdasarkan penyakit penyerta yaitu hipertensi dengan persentase 31.37%. Simpulan: Penggunaan obat golongan statin pada pasien hiperlipidemia sudah rasional. Penggunaan obat hyperlipidemia yang banyak digunakan yaitu simvastatin 20 mg.   Kata Kunci: Evaluasi Penggunaan Obat; Hiperlipidemia; Statin.
Studi kasus asuhan keperawatan pada pasien pneumonia dengan diagnosa sekunder hypertensive hearth disease Sriwiyati, Lilik; Christina, Tri Yahya; Safaruddin, Safaruddin; Andika, I Putu Juni
JOURNAL OF Pharmacy and Tropical Issues Vol. 5 No. 2 (2025): December Edition 2025
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR) Kerjasama dengan Ikatan Sarjana Farmasi Indonesia (ISFI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/pti.v5i2.3226

Abstract

Background: Pneumonia is the leading cause of death among children under five years of age. In addition to infants, the elderly and individuals with weakened immune systems are also highly susceptible to pneumonia. The incidence of pneumonia in Indonesia is on the rise. The prevalence of pneumonia in Java Province remains quite high, warranting serious attention. Nursing care for patients with pneumonia is essential, given that this disease is quite serious and significantly impairs the patient’s ability to meet the body’s oxygen needs. Purpose: To analyze nursing care for patients with pneumonia and a secondary diagnosis of hypertensive heart disease, covering the assessment, establishment of nursing diagnoses, interventions, implementation, and evaluation. Method: This study is a descriptive-analytical study using a case study approach. The purpose of the study is to describe the implementation of nursing care for a patient with pneumonia and a secondary diagnosis of hypertensive heart disease. The subject of the case study was one patient with pneumonia. Data analysis was performed using descriptive analysis.. Results: A patient with pneumonia and a secondary diagnosis of hypertensive heart disease presented with signs and symptoms of shortness of breath, chest heaviness, palpitations, and weakness; blood pressure readings indicated stage 1 hypertension. ECG revealed sinus rhythm with first-degree AV block, alternating episodes of TAVB with junctional escape rhythm and multiple PJCs; blood gas analysis indicated compensated metabolic acidosis; the P/F ratio indicated mild respiratory failure; chest X-ray showed pneumonia; and the chest X-ray revealed cardiomegaly accompanied by aortosclerosis. Based on these findings, the nursing diagnoses were established as impaired gas exchange and decreased cardiac output. The established SLKI (Specific Nursing Interventions) were acid-base balance and increased cardiac output. The established SIKI (General Nursing Interventions) were respiratory monitoring and cardiac care. Conclusion: Following treatment of a patient with pneumonia and a secondary diagnosis of hypertensive heart disease, who presented with gas exchange abnormalities and reduced cardiac output, the patient was able to achieve acid-base balance and an increased cardiac output.   Keywords: Hypertensive Heart Disease; Nursing Care; Pneumonia.   Pendahuluan: Pneumonia merupakan penyebab kematian terbesar pada anak di bawah usia lima tahun. Selain pada balita, lansia dan individu dengan sistem imun yang rendah juga sangat rentan menderita pneumonia. Kejadian pneumonia di Indonesia menunjukkan adanya peningkatan. Prevalensi pneumonia di Provinsi Jawa masih cukup tinggi sehingga memerlukan perhatian serius. Asuhan keperawatan pada pasien dengan pneumonia sangat diperlukan mengingat penyakit ini cukup serius dan sangat mengganggu kemampuan pasien dalam memenuhi kebutuhan oksigen tubuh. Tujuan: Untuk menganalisis asuhan keperawatan pada pasien pneumonia dengan diagnosa sekunder hypertensive hearth disease mulai dari pengkajian, penegakan diagnose keperawatan, intervensi, implementasi dan evaluasi. Metode: Penelitian ini adalah jenis penelitian deskriptif analitik dengan pendekatan studi kasus. Tujuan penelitian untuk mengetahui gambaran pelaksanaan asuhan keperawatan pada pasien pneumonia dengan diagnose sekunder hypertensive hearth disease. Subyek studi kasus adalah satu pasien dengan pneumonia. Analisa data menggunakan analisis deskriptif. Hasil: Pasien dengan pneumonia dengan diagnose sekunder hypertensive hearth disease didapatkan tanda dan gejala sesak nafas, dada terasa berat, jantung berdebar-debar, tubuh terasa lemah, tekanan darah menunjukkan hipertensi derajat 1, EKG didapatkan Irama sinus dengan AV block derajat 1, alternating episode TAVB dengan irama lolos junctional dengan multiple PJC, analisa gas darah menunjukkan asidosis metabolic terkompensasi, P/F rasio menunjukkan gagal napas ringan, rontgen thorax menunjukkan pneumonia, thorax menunjukkan cardiomegaly disertai aortosclerosis. Berdasarkan data tersebut ditegakkan masalah keperawatan gangguan pertukaran gas dan penurunan cardiac output. SLKI yang ditegakkan adalah keseimbangan asam basa dan curah jantung meningkat. SIKI yang ditegakkan adalah pemantauan respirasi dan perawatan jantung. Simpulan: Setelah dilakukan perawatan pada pasien pneumonia dengan diagnosa sekunder hypertensive hearth disease dengan masalah pertukaran gas dan penurunan cardiac output, pasien mampu mencapai keseimbangan asam basa dan mencapai cardiac output yang meningkat.   Kata Kunci: Asuhan Keperawatan; Hypertensive Hearth Disease; Pneumonia.

Page 6 of 6 | Total Record : 53

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