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Fakultas Farmasi UMI, Kampus II UMI, Jl. Urip Sumoharjo No.225, Panaikang, Panakkukang, Kota, Makassar,, Panaikang, Kec. Panakkukang, Macassar, Sulawesi Selatan 90231
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MPSJ
Published by Universitas Muslim Indonesia
ISSN : -     EISSN : 29870887     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Makassar Pharmaceutical Science Journal merupakan salah satu jurnal yang dikelola oleh Fakultas Farmasi Universitas Muslim Indonesia yang terbit pertama kali pada bulan Maret 2023. Makassar Pharmaceutical Science Journal merupakan jurnal ilmiah yang terbit secara on-line dan menerbitkan artikel atau karya ilmiah hasil penelitian dalam bidang farmasi sains.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 10 Documents
 1 
Search results for , issue "Vol 1 No 2 (2023)" : 10 Documents clear
ANALISIS KANDUNGAN SENYAWA FENOLIK DAN TANIN PADA ISOLA FUNGI ENDOFIT (IFEBK20) BUNGA KERSEN (Muntingia calabura L) DENGAN METODE SPEKTROFOTOMETRI UV-VIS p, irmawan jamal; Maryam, St.; Suhaenah, Asriani
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 2 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i2.33

Abstract

Bunga Kersen (Muntingia calabura L.) mengandung fungi endofit yang mampu menghasilkan metabolit sekunder yang sama dengan sel inangnya, dimana metabolit sekunder ini dari isolat fungi endofit IFEBK20 seperti senyawa fenol dan tanin yang merupakan kelompok senyawa fenolik terbesar. Pada penelitian ini bertujuan untuk mengetahui berapa kadar senyawa fenolik dan tanin yang dihasilkan dari isolat fungi endofit bunga kersen (Muntingia calabura L.) secara kuantitatif menggunakan metode spektrofotometri UV-Vis. Dari hasil penelitian menunjukkan bahwa ekstrak isolat IFEBK20 bunga kersen (Muntingia calabura L.) mengandung senyawa fenol dan tanin. Secara kuantitatif ekstrak isolat IFEBK20 bunga kersen (Muntingia calabura L.) diukur pada panjang gelombang maksimum 739,901 nm untuk fenol dengan baku pembanding asam galat, dan diukur pada panjang gelombang maksimum 738,578 nm untuk tanin dengan baku pembanding asam tanat. Hasil penelitian menunjukkan bahwa kadar rata-rata ekstrak isolate IFEBK20 bunga kersen (Muntingia calabura L.) mengandung senyawa fenol sebesar 21,447 mgGAE/g ekstrak atau 2,144 % b/b GAE, dan senyawa tanin sebesar 31,584 mgTAE/g ekstrak atau 3,158 %
Formulasi serum ekstrak daun kemangi (Ocimum basilicum L.) sebagai antioksidan khusnia, Khusnia; Mumtihanah, A.; Zulkarnain, Iskandar
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 2 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i2.39

Abstract

Flavonoid content in basil leaves can be used as an antioxidant. Serum is a preparation that is formulated from high concentrations of active substances so that the effect is absorbed more quickly by the skin. The purpose of this study was to formulate basil leaf extract serum as an antioxidant using an experimental method. Evaluation test and antioxidant test using basil leaf extract concentrations of 0.06%, 0.30%, 0.6%. Evaluation of serum preparations was carried out with parameters namely organoleptic test, homogeneity test, pH test, spreadability test, Viscosity test, stability test, and antioxidant test with the DPPH method. The results showed that after stability testing for 6 cycles the serum formula did not change color, homogeneous conditions, the average formula pH was F1 (4.659 ± 0.007), F2 (4.826 ± 0.002), F3 (4.981 ± 0.001), the viscosity of the preparation F1 ( 2356 ± 40.412 cps), F2 (2285 ± 5 cps), F3 (2176 ± 1.572 cps), the average spread of the preparation was 5.2-6.3 cm. it was concluded that the serum formula gave good results and fulfilled the parameter requirements for evaluating the physical quality of the preparation. The antioxidant test results of the serum basil leaf extract formula had IC50 values in F1 (94.605 µg/mL), F2 (74.900 µg/mL), F3 (54.695 µg/mL) the three formulas were categorized into strong antioxidants.
Uji Aktivitas Antibakteri Ekstrak Etanol Daun Kayu Jawa (Lannea coromandelica (Houtt.) Merr.) Terhadap Bakteri Penyebab Infeksi Saluran Pencernaan Dengan Metode Difusi Agar Rabbana, Rahmawati; Kosman, Rachmat; Nuryanti, Siska
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 2 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i2.41

Abstract

The purpose of this research was to determine the antibacterial activity of the ethanol extract of Javanwood leaves Lannea coromandelica (Houtt.) Merr.) against bacteria that cause digestive tract infections. The research method begins with the extraction process using the maceration method with 96% ethanol solvent and evaporated using a rotary evaporator. Java wood leaf ethanol extract was subjected to screening tests with a concentration of 0.1%; 0.5%; and 1% against the test bacteria Eschericia coli, Salmonella typhi, Shigella dysenteriae and Vibrio cholerae. MIC and MBC tests were carried out and continued with antibacterial activity tests using the agar diffusion method with variations in concentrations of 0.5%; 1%; 2%; 4%; 8%; and 16%. The results of the screening test for Escherichia coli and Shigella dysenteriae bacteria at 0.5%. MIC values for Escherichia coli bacteria at 0.125% and Shigella dysenteriae bacteria at 2%. While the MBC value for Escherichia coli bacteria is at 0.5% and Shigella dysenteriae bacteria at 2%. The results of testing the antibacterial activity of the ethanol extract of Javanwood leaves against Escherichia coli and Shigella dysenteriae bacteria had the largest diameter of the inhibition zone at a concentration of 16%, respectively 17.10 mm; and 13.56 mm which is included in the criteria of having strong inhibition. Based on the results of the ethanol extract of Javanwood leaves, it has potential as an antibacterial.
Antibacterial Activity Test of Tembelekan Leaf Ethanol Extract (Lantana camara L) Against Bacteria Causing Gastrointestinal Tract Infections Hajar, Siti; Fitriana, Fitriana; Asmaliani, Ira
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 2 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i2.51

Abstract

Tembelekan leaves have been shown to be efficacious as antioxidants, anticancer, antibiotics, antibacterial, which are known to contain alkaloids, saponins, flavonoids, and tannins. The purpose of this study was to determine the antibacterial activity of the ethanol extract of tembelekan leaves (Lantana camara L) against bacteria that cause digestive tract infections. The method used in this research is agar diffusion. Antibacterial screening test with concentrations of 0.1%, 0.5% and 1% against test bacteria E.Coli, S.Dysenteriae, V.Cholerae, S.Typhi. After that, MIC, KBM, and antibacterial activity testing were carried out. The results of the screening test gave activity at a concentration of 1% against the four test bacteria. The MIC test value obtained a concentration of 0.5% on E. Coli bacteria and V. cholerae bacteria, a concentration of 0.25% on S. Dysentriae bacteria and S. typhi bacteria. KBM value of 1% concentration on E. coli and V. Cholerae bacteria, 0.5% concentration on S. Dysentriae and S.typhi bacteria. The results of the antibacterial activity test of the ethanol extract of tembelekan leaves against the test bacteria obtained the largest diameter of the inhibition zone at a concentration of 20%. Based on the research, the ethanol extract of tembelekan leaves has antibacterial activity.
Profil Pengkajian Resep Racikan Pediatri Pasien Rawat Jalan di Rumah Sakit Umum Daerah Labuang Baji Periode Bulan Juni-Desember 2022 Annisyah, Nur; Ririn, Ririn; Azizah, Rizqi Nur
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 2 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i2.68

Abstract

Prescription screening is one of the pharmaceutical services used to minimize the occurrence of errors in drug prescribing. The purpose of this study was to review the prescription of pediatric concoctions for outpatients in June-December 2022 at Labuang Baji Hospital based on Permenkes No. 72 of 2016 concerning Pharmaceutical Service Standards in Hospitals. non-experimental descriptive research with data collection was carried out retrospectively. The population in this study was 217 prescription sheets. The results showed the percentage of completeness of administrative aspects, namely patient name 98%, patient age 41%, gender 0%, body weight 25%, height 1%, doctor's name 91%, address and doctor's signature and license number 100%, prescription date 93%, prescription origin unit 95%. The suitability of the pharmaceutical aspects, namely the name of the drug, dosage form, amount of drug, rules and methods of use 100%, dosage strength 0%, no incompatibility, 35% hygroscopic & 65% photolysis. The suitability of clinical aspects, namely the accuracy of the indication and the accuracy of the time of use of 100%, there were no drugs that were duplicated, for the accuracy of the dose there were 9% overdose and 5% underdose. From the results of this study it can be concluded that the prescription at Labuang Baji Hospital has not fully met the suitability of the prescription based on Permenkes RI No. 72 of 2016 concerning Pharmaceutical Service Standards in Hospitals.
Uji Aktivitas Antibakteri Ekstrak Etanol Daun Benalu Batu (Begonia medicinalis) Terhadap Bakteri Uji Penyebab Infeksi Saluran Pencernaan pratiwi, dita; Fitriana, Fitriana; Amirah, Sitti
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 2 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i2.70

Abstract

Benalu batu (Begonia medicinalis) mengandung senyawa sekunder seperti polifenol, saponin, flavonoid, dan tannin yang mempunyai aktivitas sebagai antimikroba. Penelitian ini bertujuan untuk mengetahui aktivitas antimikroba dari ekstrak etanol daun benalu batu terhadap bakteri penyebab infeksi saluran pencernaan. Hasil penelitian yang diperoleh pada uji skrining terhadap bakteri uji Escherichia coli, Salmonella typhi, Shigella dysenteriae, dan Vibrio chloreae memberikan aktivitas pada konsentrasi 6% untuk bakteri E. Coli, S. dysentriae V. Cholerae. Pengujian dilanjutkan dengan penentuan nilai KHM menggunakan metode dilusi cair dan KBM menggunakan metode dilusi padat. Hasil uji KHM yang diperoleh pada konsentrasi 18% terhadap bakteri uji. Hasil uji KBM yang diperoleh yaitu 18% untuk bakteri E. Coli, 12% untuk bakteri S.Dysentriae, dan 6% untuk bakteri V. Cholerae. Selanjutnya dilakukan pengujian aktivitas antimikroba menggunakan metode difusi agar dengan seri konsentrasi yaitu 18%, 24%, dan 30%. Hasil uji aktivitas antibakteri ekstrak etanol daun benalu batu diperoleh diameter zona hambatan terbesar pada konsentrasi 30%. Hasil uji statistik data diameter zona hambatan menunjukkan adanya perbedaan kemampuan penghambatan pertumbuhan bakteri antara konsentrasi 18% dan 24% serta 18% dan 30%, kemudian antara konsentrasi 24% dan 30% memiliki kemampuan yang sama dalam menghambat pertumbuhan bakteri. Berdasarkan penelitian, ekstrak etanol daun benalu batu memiliki potensi sebagai antibakteri.
UJI AKTIVITAS ANTIDIABETES EKSTRAK ETANOL BIJI ALPUKAT (Persea americana Mill.) SECARA IN VITRO DENGAN MENGGUNAKAN SPEKTROFOTOMETRI UV-VIS Zulhijja .S, Faradiba; Abidin, Zainal; Wati, Aulia
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 2 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i2.75

Abstract

Diabetes mellitus is a metabolic disease characterized by hyperglycemia, which is caused by insulin resistance and dysfunction of insulin secretion. Avocado is used as a traditional medicine to treat various diseases, one of which is the seed of the avocado which contains alkaloids, polyphenols, tannins, flavonoids, triterpenoids, quinones, saponins, monoterpenes and sesquiterpenes and can lower blood glucose levels. The aim of this study was to determine the antidiabetic potential of ethanol extract of avocado seeds (Persea americana Mill.) in vitro using the Nelson Somogyi method. The test began with preparing a series of sample ethanol extract concentrations with concentrations of 40, 50 and 60 ppm using a UV-Vis spectrophotometer measured at a wavelength of 745 nm. The results of testing the anti-diabetic activity by the test samples were able to show the effectiveness of reducing glucose levels in vitro by showing the EC50 value in the ethanol extract sample was 59.1018 μg/mL. From the results of the study it can be concluded that the ethanol extract of avocado seeds (Persea americana Mill) has activity in reducing glucose levels.
Identifikasi Gugus Fungsi Limbah Minyak Trafo yang Digunakan sebagai Minyak Obat Luka Menggunakan FTIR Hidayanti, Nurul; Rahmawati, Rahmawati; Maryam, St.
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 2 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i2.92

Abstract

Communities living close to PLN empirically use waste transformer oil as a medicine for wounds such as cuts or cuts and burns such as being exposed to oil or hot cooking utensils. Transformer oil has the main function as an insulating medium and as a coolant. This study aims to determine the chemical components contained in transformer oil waste by using FTIR. The results of research on transformer oil waste using the FTIR method showed that there were carboxyl functional groups, amide groups, aromatic rings, nitro groups and alkyl groups.
Analisis Kandungan Rhodamin B Pada saus Tomat Yang Beredar DiKabupaten Wajo Kecamatan Belawa Menggunakan Metode Spektrofotometri UV-Vis Hudayanti, Andi Isti; Widiastuti, Harti; Suhaenah, Asriani
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 2 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i2.104

Abstract

Rhodamin B is a synthetic dye that is used as a dye for the textile industry which is dangerous. Rhodamin B is often misused as a food and cosmetic coloring agent, where Rhodamin B can cause irritation to the digestive tract, poisoning and can even cause cancer. This study aims to determine the presence or absence of Rhodamin B content in tomato sauce samples circulating in Wajo District, Belawa District. In this study used six samples marked with S1, S2, S3, S4, S5, and S6. Qualitative analysis used the TLC test and quantitatively for positive samples used the Uv-Vis spectrophotometry method. From the research results, it was found that S1, S2, S3, S4, S5 were negative for Rhodamin B while S6 was positive for Rhodamin B where the Rf value was 0.68, the color of the pink stain matched the Rhodamin B comparison.
Studi Literatur Penetapan Kadar Fenolik Ekstrak Etanol Daun Turi (Sesbania grandiflora L) secara Spektrofotometri UV-';Vis aenung, nurul; Baits, Muzakkir; Trihadi, Andi
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 2 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i2.189

Abstract

Turi plant (Sesbania grandiflora L) is a fabaceae plant that is widely used by the local community as a medicine for sprains, wounds and bruises.Turi plants contain active compounds of alkaloids, flavonoids, saponins, triterpenoids, phenolics and tannins. The purpose of this study was to determine how much phenolic content contained in the ethanol extract of Turi leaves using UV-Vis Spectrophotometry . The research method used is the Literature Review method by collecting journals conducted online using Google and Google Scholar data bases, then selected 5 journals in accordance with the criteria in the study of literature. Based on the results of research from 5 journals it can be concluded that the ethanol extract of turi leaves has different levels in a row, namely 3,7± 0,44 mg/g, 8,9 ± 1,35 mg, 1445,9 ± 49,33 µg, 88,56 ± 0,09 mg/g dan 0,137 mg.

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