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Fakultas Farmasi UMI, Kampus II UMI, Jl. Urip Sumoharjo No.225, Panaikang, Panakkukang, Kota, Makassar,, Panaikang, Kec. Panakkukang, Macassar, Sulawesi Selatan 90231
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MPSJ
Published by Universitas Muslim Indonesia
ISSN : -     EISSN : 29870887     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Makassar Pharmaceutical Science Journal merupakan salah satu jurnal yang dikelola oleh Fakultas Farmasi Universitas Muslim Indonesia yang terbit pertama kali pada bulan Maret 2023. Makassar Pharmaceutical Science Journal merupakan jurnal ilmiah yang terbit secara on-line dan menerbitkan artikel atau karya ilmiah hasil penelitian dalam bidang farmasi sains.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 100 Documents
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Perbandingan Kadar Perbandingan Kadar Fenolik Ekstrak Daun Karet Kebo (Ficus elastica) Hasil Ekstraksi Bertingkat Menggunakan Metode Spektrofotometri UV-Vis mondo, zhafira anggraini; Suhaenah, Asriani; Tahir, Masdiana
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.278

Abstract

ZHAFIRA ANGGRAINI MONDO. Comparison of Phenolic Content of Rubber Kebo (Ficus elastica) Leaf Extract Results from Multilevel Extraction Using the UV-Vis Spectrophotometry Method (Supervised by Asriani Suhaenah and Masdiana Tahir). The kebo rubber plant (Ficus elastica) is used by Indonesian people as traditional medicine, namely medicine to lower blood pressure, lower cholesterol, stroke, and reduce joint pain. Kebo rubber leaves (Ficus elastica) contain secondary metabolites such as saponins, polyphenols, flavonoids and tannins. This research aims to determine the comparison of phenolic compound levels of kebo rubber leaf extract (Ficus elastica) resulting from multilevel extraction using the UV-vis spectrophotometric method. The extraction process uses 3 different types of solvents, namely n-hexane (nonpolar), ethyl acetate (semipolar) and ethanol (polar) using a sonicator. Determination of phenolic content using the UV-Vis spectrophotometric method, with a maximum wavelength of 772 nm and using gallic acid as a comparison. The results showed that the levels were influenced by the solvent used in comparing the phenolic compound levels of kebo rubber leaf extract (Ficus elastica) with the multilevel extraction method, namely n-hexane extract 3,774 mgGAE/g, ethyl acetate extract 12,696 mgGAE/g, ethanol extract 74,396 mgGAE/g g.
PENENTUAN KADAR TANIN PENENTUAN KADAR TANIN PADA EKSTRAK ETANOL DAUN KARET KEBO (Ficus elastica Roxb. ex Hornem) DENGAN MENGGUNAKAN METODE SPEKTROFOTOMETRI UV-Vis renhoran, aulia azahra; Suhaenah, Asriani; Muflihunna, A.
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.281

Abstract

This research aims to determine the tannin content in the ethanol extract of kebo rubber leaves (Ficus elastica Roxb. ex Hornem). Rubber plants (Ficus elastica Roxb. ex Hornem) are plants that are widely used as traditional medicine, the leaves of this plant are used as medicine to treat diarrhea. , stops bleeding and treats hemorrhoids. Many of the benefits and properties of the kebo rubber plant (Ficus elastica Roxb. ex Hornem) cannot be separated from the compounds contained in it, such as phenolics, tannins, flavonoids and saponins. Simplicia was extracted using the maceration method with 96% concentration of ethanol solvent for 3x24 hours. Determination of tannin content using the UV-Vis spectrophotometric method, with a maximum wavelength of 772 nm, using gallic acid as a comparison. The research results showed that the total tannin content in the ethanol extract was an average of 31.708mgQE/g.
Comparasion Of Levels Perbandingan Kadar Flavonoid Ekstrak Daun Karet Kebo (Ficus elastica)Hasil Ekstraksi Bertingkat Menggunaka evatiara, nur; Suhaenah, Asriani; Tahir, Masdiana
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.282

Abstract

NUR EVATIARA. Comparison of flavonoid levels of rubber plant leaf extract (Ficus elastica) resulting from multilevel extraction using the UV-Vis spectrophotometric method. (Supervised by Asriani Suhaenah and Masdiana Tahir). Rubber plant (Ficus elastica) is a plant in the Moraceae family whose leaves have been empirically stated to contain secondary metabolite compounds such as saponins, polyphenols, flavonoids and tannins which have been used as medicine for coughing up blood, improving urine flow, relieving pain and improving blood circulation. The aim of this research was to determine the comparison of levels of flavonoid compounds in rubber plant leaf extract (Ficus elastica) resulting from multilevel extraction using the UV-Vis spectrophotometric method. The multistage extraction process uses 3 different types of solvents, namely n-hexane (nonpolar), ethyl acetate (semipolar), and ethanol (polar) using a sonicator. Determination of flavonoid levels using the UV-Vis spectrophotometric method, with a maximum wavelength of 432 nm and quarcetin as a comparison. The research results were influenced by the solvent used in comparing the levels of flavonoid compounds, namely rubber plant leaf extract (Ficus elastica) with a multilevel extraction method, namely N-hexane extract 7.161 mgQE/g, Ethyl acetate extract 7.663 mgQE/g, 96% Ethanol extract 10.592 mgQE/g g.
antioxidant activity Uji aktivitas antioksidan ekstrak daun karet kebo (Ficus elastica) dengan menggunakan metode maserasi bertingkat Yani, Indah Ahmad; Suhaenah, Asriani; Aminah, Aminah
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.283

Abstract

Kebo rubber (Ficus elastica) is one type of plant in Indonesia as a medicine to lower blood pressure, reduce cholesterol, stroke and reduce joint pain. In addition, Kebo rubber (Ficus elastica) leaves are one of the ficus species that are thought to be rich in polyphenolic compounds so that they can act as antioxidants. Antioxidants are compounds that can be used to counteract free radicals. Food fiber and antioxidants are two types of components that are very beneficial in improving health and being able to prevent various diseases. This study aims to analyze the antioxidant activity of rubber kebo (Ficus elastica) leaf extract using the DPPH method. The maceration process uses 3 different types of solvent, namely n-hexane (non-polae), ethyl acetate was measured at 510 nm wavelength with quercetin as the standard comparator. The measurement result for n-hexan extract obtained IC50 of 531,90 µg/mL, ethyl acetat obtained IC50 of 188,06 µg/mL, and for ethanol extract obtained IC50 of 874,73 µg/mL.
PROFIL PENYIMPANAN OBAT Profile penyimpanan obat di Puskesmas wosu Kabupaten Morowali David, Moh; Nurlina, Nurlina; Zulkarnain, Iskandar
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.284

Abstract

Drug storage profiles are an importand factor ini drug management at community health center, because with proper storage of medicines it will be easier and more effective to guarantee the quality of medicines. This research aims to determine the procedures for regulating drugs and improving the quality of drug storage at the wosu healty center, bungku barat sub-district, morowali district. Data collection was carried out through interviews and using observation sheets regarding aspects of drug storage in community health centers including general aspects, special aspectsinclude requirements for drug storage warehouses with 15 aspects assesed with a persentage of 100%, special aspects include requirements of drug preparation with 5 aspects assessed with a percentage of 100% and document review includes procedures for recording drugs. From the result of research in the field there are still several problems that do not meet standards. How ever in general the results of this study show that drug storage, preparation of drugs, and recording of drugs at the wosu comunity health center, bungku barat sub- district, morowali regency are in the good category.
Antioxidant activity Antioxidant activity of ethanol extract of bitti leaves (Vitex cofassus Reinw. ex. Blume) using the dpph free radical scavenging method Bahari, Dita Wulan; Suhaenah, Asriani; Muflihunna, A.
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.288

Abstract

Antioxidants are compounds that can counteract free radicals in the body, reduce oxidation in cells and cell damage. The purpose of this study was to determine the antioxidant activity of ethanol extract of bitti leaves (Vitex cofassus Reinw. Ex. Blume with DPPH (2,2- diphenyl-1-picrylhydrazyl) scavenging method. The absorbance was measured by UV-Vis spectrophotometer at 510 nm wavelength. The results showed the presence of antioxidant activity with IC50 value of 56.59 μg/mL with strong antioxidant activity category, while quercetin as a comparator has very strong antioxidant activity with IC50 value of 5.93 μg/mL.
Antioxidant Activity Aktivitas Antioksidan Ekstrak Etanol Daun Lerak (Sapindus rarak DC) Dengan Metode Peredaman Radikal Bebas DPPH Asri, Fitriani; Suhaenah, Asriani; Maryam, St.
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.289

Abstract

FITRIANI ASRI. Antioxidant Activity Of Ethanol Extract Of Lerak eaves (Sapindus rarak) Using The DPPH Free Radical Reduction Method (Supervised by Asriani Suhaenah dan St. Maryam) Lerak leaves (Sapindus rarak) are a traditional plant used by the community to treat various diseases. The secondary metabolic compounds contained in the lerak plant (Sapindus rarak) which have potential as antioxidants are flavonoids, alkaloids, saponins, tannins, quinones, steroids and triterpenoids which are obtained through extraction using ethanol solvent. This research aims to determine the antioxidant activity of the ethanol extract of lerak leaves (Sapindus rarak) using the DPPH free radical reduction method (1,1-diphenyl-2-picrihydrazyl). The antioxidant value was measured using UV-Vis spectrophotometry at a wavelength of 516 nm. The calculation results show an IC50 value of 876,592 μg/mL (very weak category) while quercetin as a comparison has very strong antioxidant activity with an IC50 value of 1,882 μg/mL.
Analisis Kandungan Kimia Dan Penetapan Kadar Polifenol Daun Lerak (Sapindus rarak DC) Dengan Metode Spektrofotometri UV-Vis Salim, Medina; Maryam, St.; Muflihunna, A.
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.290

Abstract

MEDINA SALIM. Chemical Content Analysis and Determination of Lerak Leaf Polyphenol Content (Sapindus rarak DC) by UV-Vis Spectrophotometry Method (Guided by St. Maryam and A. Muflihunna). Lerak contains polyphenolic compounds that reduce blood sugar levels. This study aims to determine the chemical content contained in lerak leaf extract (Sapindus rarak DC) and find out how much polyphenol compounds in the sample. The samples were macerated for 3 days using 96% ethanol solvent, the extraction process was carried out until obtaining an extract yield of 9.323 grams, then two tests were carried out, namely qualitative and quantitative, The qualitative test uses a wet reagent while the quantitative test uses the UV-Vis spectrophotometry method. The maximum wavelength used was 768 nm with gallic acid as a comparison. Based on the study, the results of ethanol extract of lerak leaves (Sapindus rarak DC) contain secondary metabolites, namely saponins, steroids, polyphenols and tannins and the result of polyphenol content is 21,168 mgGAE/g.
analisis kadar analisis kadar senyawa tanin pada teh daun tanaman kakao (theobroma cacao L.) secara spektrofotometri UV-Vis arifin, nurrizky afiah; Suhaenah, Asriani; Maryam, St.
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.291

Abstract

Cocoa leaves (Theobroma cacao L.) contain secondary metabolite compounds, namely flavonoids, saponins, tannins, theobromine, caffeine, anthocyanins, leucoanthocyanins and catechol. This research aims to determine the levels of tannin compounds contained in tea preparations from the leaves of the cocoa plant (Theobroma cacao L.) based on a comparison of growing places, namely Wajo, Jeneponto and Malino. The research was carried out qualitatively using wet reagents and quantitatively using the UV-Vis spectrophotometric method. Based on the qualitative test results, FeCl3 1% reagent produces a green solution blackish, the gelatin test produces precipitation, while the potassium ferricyanide and ammonia reagent produces a dark brown color, these results indicate that cocoa leaves contain tannin compounds, for the quantitative test it is measured using UVVis spectrophotometry at a maximum wavelength of 772 nm with a reference, namely gallic acid. . The results obtained for the Wajo area were 1,618mgGAE/g, Jeneponto 2,334mgGAE/g, and Malino 1,030mgGAE/g, based on these data it can be concluded that cocoa leaves contain tannin compounds and the highest levels are in the Jeneponto area.
A LITERATUR REVIEW : VCO SEBAGAI ANTI KETOMBE Aliefia, Nur; Mursyid, A. Mumtihanah; hasrawati, A.
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 4 (2025)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i4.292

Abstract

Hair serum has become a popular care product to maintain healthy and beautiful hair. Pure coconut oil (VCO) is known to have great potential in hair care because of its natural nutritional content. One of the main ingredients in VCO is lauric acid. The high lauric acid content in this vco has antimicrobial and antifungal properties which are effective against dandruff. Dandruff is flakes of (dead) scalp that peel off. The epithelium that makes up the scalp is a stratified squamous epithelium that continuously grows, thereby pushing the old epithelium above it to the surface where it will then die and eventually peel off (corneocytes). Where the use of VCO can prevent dandruff. However, VCO is not applied directly to the scalp, therefore a serum preparation is made first. The advantage of serum compared to other preparations is that it is highly concentrated so it is absorbed more quickly into the skin. Based on the many health problems that often occur on the scalp and hair, the aim of the research is to conduct a literature review on what ingredients are contained in VCO so that it can be made into a hair serum preparation. The method used in reviewing this article is to carry out online search process using several search engines such as Google Scholar, Scopus, and Schoolar with the keywords: Virgin Coconut Oil, Dandruff, Emulgel, Serum. The sources obtained are international and national journals. Articles were selected based on inclusion criteria, namely those published in the last 10 years with suitability for writing keywords, relevance of writing results and discussion.

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