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Fakultas Farmasi UMI, Kampus II UMI, Jl. Urip Sumoharjo No.225, Panaikang, Panakkukang, Kota, Makassar,, Panaikang, Kec. Panakkukang, Macassar, Sulawesi Selatan 90231
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MPSJ
Published by Universitas Muslim Indonesia
ISSN : -     EISSN : 29870887     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Makassar Pharmaceutical Science Journal merupakan salah satu jurnal yang dikelola oleh Fakultas Farmasi Universitas Muslim Indonesia yang terbit pertama kali pada bulan Maret 2023. Makassar Pharmaceutical Science Journal merupakan jurnal ilmiah yang terbit secara on-line dan menerbitkan artikel atau karya ilmiah hasil penelitian dalam bidang farmasi sains.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 100 Documents
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PROFIL PENYIMPANAN OBAT DI GUDANG INSTALASI FARMASI RUMAH SAKIT MITRA MANAKARRA MAMUJU SULAWESI BARAT Hokilia, Resky Nov; Herman, Hendra; hasrawati, A.
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.213

Abstract

Pharmaceutical services in hospitals including the management of pharmaceutical supplies including drug storage to pay attention to storage so that errors do not occur during the drug storage process and drug storage is a very important step in maintaining the quality of medicines. Drug storage must guarantee the quality and safety of the drug in accordance with pharmaceutical requirements. The purpose of this study was to determine the profile of drug storage in the Pharmacy Installation Warehouse at Mitra Manakarra Mamuju Hospital, West Sulawesi and its compliance with regulations in force in Indonesia. This study used a descriptive method by conducting interviews and observations. The respondents in this study consisted of the person in charge of the pharmacy and the person in charge of the warehouse at the Pharmacy Installation at Mitra Manakarra Hospital Mamuju, West Sulawesi. Collecting data in research by means of observation, interviews and data analysis. Analysis Percentage of storage areas in good condition with a yield value of 93.1%, storage areas for narcotics, psychotropics and precursors in good condition with a yield value of 100%, method and system aspects in good condition with a yield value of 91.6% and stock cards in good condition with yield values 90%.
Profil Peresepan Penggunaan Obat Gastritis Pada Pasien Rawat Jalan di RSUD Batara Guru Belopa Periode Januari-Maret 2023 Muris, Dian Indri; Herman, Hendra; hasrawati, A.
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.214

Abstract

Gastritis is a stomach disease caused by inflammation of the stomach wall. That is why gastritis is often referred to as inflammation of the stomach. The causes of gastric disorders include infection with Helicobacter pylori bacteria, side effects of using non-steroidal anti-inflammatory drugs (NSAIDs), poor lifestyle, and prolonged stress. This study aims to determine the prescription of gastritis drugs in outpatients at Batara Guru Belopa Hospital based on patient characteristics (age and gender), as well as to see the suitability and classification of gastritis drugs which include dose and frequency, drug type parameters, drug combinations, and drug interactions prescribed. The method in this study is descriptive research with retrospective research data type. The sample used in this study used purposive sampling method with sampling based on inclusion criteria where 314 gastritis prescription sheets were obtained. Based on the results obtained, it was found that female patients had a greater percentage than men with 208 prescriptions (66.24%), while the largest age group of gastritis patients was the late adulthood age group with ages 35-54 having the largest percentage of 26.75%. The use of gastritis drugs based on the most prescribed type of single therapy is Omeprazole as many as 79 prescriptions (49.69%), the most prescribed type of two drug combination therapy is Omeprazole and Sucralfat as many as 47 prescriptions (31.97%), and for the type of three drug combination therapy the most prescribed is Omeprazole + Ranitidine + Sucralfat (42.85%).
PROFIL PENGELOLAAN OBAT DI RSKD IBU DAN ANAK SITI FATIMAH KOTA MAKASSAR Said, Mohammad Septiansyah Miftahul; Mursyid, A. Mumtihanah; Aztriana, Aztriana
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.219

Abstract

Pengelolan obat merupakan pelayanaan manajerial rumah sakit yang merupakan suatu siklus kegiatan dimulai dari pemilihan, perencanaan kebutuhan, pengadaan, penerimaan, penyimpanan, pendistribusian, pemusnahan dan penarikan, pengendalian, serta administrasi yang diperlukan bagi kegiatan Pelayanan Kefarmasian. Tujuan dari penelitian ini adalah untuk mengetahui dan menyajikan data tentang pegelolaan obat dalam bentuk deskriptif di RSKD Ibu dan Anak Siti Fatimah Kota Makassar. Penelitian ini dilakukan dengan metode kombinasi kualitatif dan kuantitatif yang disajikan secara deskriptif. Dari hasil penelitian diketahui bahwa Profil Pengelolaan Obat di RSKD Ibu dan Anak Siti Fatimah Kota Makassar untuk tahap Pemilihan, Perencanaan Kebutuhan, Pengadaan, Pendistribusian, Pemusnahan dan Penarikan, Pengendalian, dan Administrasi telah sesuai dengan regulasi yang berlaku dengan persentase kesesuaian mencapai 100% dan termasuk dalam kriteria Sangat Baik, sedangkan untuk tahap Penerimaan hanya mencapai persentase kesesuaian 77,77% dan termasuk dalam kriteria Baik, dan untuk Penyimpanan hanya mencapai persentase kesesuaian 92,98% dan termasuk dalam kriteria Sangat Baik. Kesimpulan pengelolaan obat di RSKD Ibu dan Anak Siti Fatimah belum sepenuhnya sesuai dengan standar regulasi Permenkes Nomor 72 Tahun 2016 Tentang Standar Pelayanan Kefarmasian di Rumah Sakit dan Petunjuk Teknis Standar Pelayanan Kefarmasian di Rumah Sakit Tahun 2019.
ANTIOXIDANT ACTIVITY TEST OF THE ETHANOL EXTRACT OF AVOCADO SEED (Persea americana Mill.) USING THE FRAP METHOD Ohorela, Indah Kartika; Maryam, St.; Suhaenah, Asriani
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.221

Abstract

Avocado seeds (Persea americana Mill.) are a plant that is useful as a traditional medicine. The ethanol extract of avocado seeds contains several secondary metabolite compounds, namely alkaloids, triterpenoids, tannins, flavonoids and saponins. The aim of this research was to determine the antioxidant activity contained in avocado seed extract (Persea americana Mill.). using the FRAP method which was measured with a UV-Vis spectrophotometer at a wavelength of 794 nm. Extraction of avocado seeds (Persea americana Mill.) using the maceration method using 96% ethanol solvent. The results show that the antioxidant activity of the ethanol extract of Avocado Seeds is 42.448 mgQE/g of extract, which means that every 1 gram of ethanol extract of avocado seeds (Persea americana Mill.) is equivalent to 42,488 mg of quercetin.
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL KULIT PISANG RAJA (Musa paradisiaca L.) SEBAGAI BAHAN BAKU PEMBUATAN ICE CREAM DENGAN METODE FERRIC REDUCING ANTIOXIDANT POWER Abidin, Zainal; Aminah, Aminah; Ummum, Andi
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 4 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i4.224

Abstract

Antioxidants are defined as inhibitors that work to inhibit oxidation by reacting with reactive free radicals to form stable unreactive free radicals. Antioxidants are substances that can delay, slow down and prevent the oxidation process or neutralize free radicals. Plantain peel contains several metabolite compounds that have the potential to have antioxidant activity such as saponins, polyphenols and tannins, flavonoids and terpenoids. Banana peel extract has high antioxidant activity. The methanol extract of banana peels was higher in total flavonoids and phenolics compared to the n-hexane extract of banana peels. The aim of this research was to test the antioxidant activity of the ethanol extract of plantain peel using the FRAP (Ferrc Reduxing Antioxidant Power) method. The extraction method for plantain peel uses the maceration method with 96% ethanol solvent. The ethanol extract of plantain peel was then added with several FRAP reagents then measured using a UV-Vis spectrophotometer at a wavelength of 720 nm with quercetin as a comparison and the results of the quercetin test obtained a linearity equation y = 0.0207x + 0.0114 with a correlation coefficient value of r = 0.9904. The results showed that the ethanol extract of plantain peel had antioxidant activity of 26.5828 mgQE/g extract.
POLA PENGGUNAAN ANTIBIOTIK PADA PASIEN TUBERKULOSIS DI PUSKESMAS PEKKAE KABUPATEN BARRU SULAWESI SELATAN PERIODE JANUARI – DESEMBER 2022 Yuliana, Dewi; Putra, Bayu; Syahrul, Andi Ahmad
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.229

Abstract

ANDI AHMAD SYAHRUL, This study aims to determine the pattern of antibiotic use in tuberculosis patients at the Pekkae Health Center, Barru in 2022. The method used is an observation method using a sampling technique, namely total sampling. The results showed that the dominant male patients were 59.1%; aged 45-54 and 55-64 as much as 22.72%. The use of drugs was adjusted to the patient's weight with intensive phase treatment of 3 2KDT tablets which was 50% then 4 4KDT tablets and 4 2KDT tables which were 27.27% then 3 4KDT tablets and 4 2KDT tablets which were 13.63% and 2 4KDT tablets and 2 2KDT tablets as much as 9.1%. The conclusion in this study is that the use and suitability of OAT is based on the TB control guidelines of the Indonesian Ministry of Health in 2016, which was used in 3 patients who had an increase in the number of tablets taken in combination doses and 1 patient there was a decrease in the number of tablets taken in combination doses and the pattern of using drugs with a fixed dose combination containing rifampicin 150 mg, isoniazid 75 mg, pyrazinamide 400mg, ethambutol 275 mg
A LITERATUR REVIEW : AKTIVITAS IMUNOMODULATOR PADA TANAMAN HERBAL Yuliana, Dewi; Handayani, Dian Pratiwi; Purnamasari, Vina
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 4 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i4.230

Abstract

Health problems that often occur in Indonesia are problems related to diseases caused by free radicals. The presence of free radicals can trigger damage to cells and can disrupt the body's immune system. The immune system can be enhanced or suppressed, one way is by administering immunomodulators. Several natural compounds have the ability to increase immune system activity, including flavonoids, curcumin, limonoids, vitamin C, vitamin E and catechins. Phenolic components such as flavonoids and polyphenols can improve the immune system by increasing Interleukin-12 (IL-12) and lymphocyte proliferation. Based on the many health problems that arise in Indonesia due to the presence of free radicals, the aim of the research is to conduct a literature review on the mechanism of action of herbal plants as immunomodulators and the methods used to determine the mechanism of action of natural immunomodulators. The method used to review this article is to carry out an online search process using several search engines such as PubMed, Scopus, ProQuest and Schoolar. Based on reference studies, several herbal plant extracts act as immunomodulators with different activities such as increasing the activity of Immunoglobulin M (IgM), reducing the number of leukocytes, stimulating the body's immunity with flavonoid content and increasing the ability of phagocytosis.
potensi ekstrak alga merah jenis Eucheuma cottoni sebagai antibakteri faridah, susanti; Nuryanti, Siska; Rusli, Rusli
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.232

Abstract

One type of algae cultivated in Indonesia is the red algae Eucheuma cottoni. Red algae are able to produce active metabolite ingredients to protect themselves from attacks by disease and predators. Initially, algae was only used for vegetables and it was not known what substances were contained in algae. As time goes by, knowledge about algae continues to grow. The red algae Eucheuma cottoni contains the chemical carrageenan, a polysaccharide compound produced from various types of red algae that has antimicrobial, anti-inflammatory, antipyretic, anticoagulant and other biological activities. This research aims to determine the potential of red algae extract as an antibacterial. This research uses a literature study approach where references are obtained through 4 data bases, namely Google Scholar, PubMed, Science Direct and Garuda, then based on the search, 8 journals are obtained that meet the inclusion and exclusion criteria. Based on the results of literature studies, it was found that red algae extract has antibacterial activity against the bacteria Salmonella thypi, Staphylococcus aureus, Staphylococcus epidermidis, Bacilus subtilis, and Escherichia coli. Key words: (Antibacterial, Eucheuma cottoni, Red Algae).
UJI SKRINING AKTIVITAS ANTIBAKTERI FRAKSI n-HEKSAN DAUN SEREH (Cymbopogon citrantus) TERHADAP BAKTERI PENYEBAB INFEKSI KULIT Priatna, Nabilah Hana; Nuryanti, Siska; Rusli, Rusli
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.233

Abstract

Indonesia as a tropical country has a diversity of biological natural resources. This diversity is very beneficial, especially with the large number of plant species that can be used as medicine. One plant that is believed to be used as medicine is lemongrass which has lush and dense leaves. Lemongrass leaves (Cymbopogon citratus) is one of the medicinal plants and can be used as a kitchen spice. Lemongrass plants are very easy to find in Indonesia and contain alkaloids, saponins, tannins, polyphenols, flavonoids, and essential oils. Saponins and essential oils are the main group of chemicals that can exert activity against microbes. This study aims to conduct a screening test of antibacterial activity of the n-hexan fraction of lemongrass leaves (Cymbopogon citrantus) against bacteria that cause skin infections. This research method was conducted experimentally to test the antibacterial activity of lemongrass leaves by screening test. The results in this study, the n-hexan fraction of lemongrass leaves can inhibit the growth of test bacteria Staphylococcus aureus, Pseudomonas aureginosa, Staphylococcus epidermidis, and Propionibacterium acne. It can be concluded that lemongrass leaves (Cymbopogon citrantus) have antibacterial activity.
Analisis Kadar Senyawa Polifenol Dari Teh Daun Tanaman Cacao (Theobroma cacao L.) Secara Spektrofotometri UV-Vis Desi, Nilma Sri; Maryam, St.; Tahir, Masdiana
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.242

Abstract

. Cocoa leaves (Theobroma cacao L.) contain secondary metabolites such as polyphenol compounds, flavanoids, saponins and tannins which are the largest group of phenolic compounds that act as antioxidant compounds. This study aims to determine the levels of polyphenolic compounds produced from cocoa leaf tea preparations (Theobroma cacao L.) based on the comparison of growing places, namely the Wajo, Jeneponto and Malino regions. Quantitative analysis using UV-Vis spectrophotometric method. based on qualitative analysis by Thin Layer Chromatography method using mobile phase n- hexanes: ethyl acetate: methanol with a ratio (2: 7: 2). Based on the results showed that the preparation of cocoa leaf tea (Theobroma cacao L.). As well as quantitative analysis measured at a maximum wavelength of 768 nm with gallic acid comparator standard. Tea samples contain polyphenolic compounds based on the Rf value equivalent to gallic acid comparator of 0.6. based on the analysis of levels from the Wajo area of 16.238 mgGAE/g, Jeneponto area 18.102 mg/GAE/g, and Malino area 6, 752 mgGAE/g and rf value of gallic acid comparator 0.630; rf value of samples from Jeneponto area 0.6; Wajo 0.6 and Malino 0.615. From the above results, it can be concluded that there are polyphenol compounds in tea samples from each region and the largest polyphenol content is found in the Jeneponto area.

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