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Vincentius Widya Iswara
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Jurnal Widya Medika
Published by Universitas Katolik Widya Mandala Surabaya
ISSN : 23380373     EISSN : 26232723     DOI : https://doi.org/10.33508/jwm
Core Subject : Health,
Medicine & Pharmacology
Jurnal Widya Medika is the official publication media of Widya Mandala Surabaya Catholic University, Faculty of Medicine. Jurnal Widya Medika publishes original research articles, case reports, and literature reviews from scientists of various medical education and research institutions, including select scientific works from medical students. All articles published had undergone plagiarism checks, editorial review by the editorial board, and peer review by experts from their respective fields in order to maintain the high standard of articles published in Jurnal Widya Medika.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 7 Documents
 1 
Search results for , issue "Vol. 9 No. 1 (2023): April" : 7 Documents clear
CHARACTERISTICS OF MATERNAL PREGNANCY AND CHILDBIRTH IN PAYANGAN SUB-SUB-DISTRICT, BALI Anny Eka Pratiwi; Ni Made Hegard Sukmawati
JURNAL WIDYA MEDIKA Vol. 9 No. 1 (2023): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v9i1.4137

Abstract

Health and nutrition during pregnancy has a close relationship with child development. Poor nutritional status during pregnancy can have an impact on fetal growth restriction (FGR), low birth weight (LBW) and stunting. Efforts to reduce the prevalence of stunting in Indonesia are carried out through the 1000 days of life program. The Faculty of Medicine and Health Sciences (FKIK) of Warmadewa University integrates the first 1000 days program in the field of education through the implementation of community-oriented medical education. This study aims to provide an overview of the characteristics of pregnancy and childbirth obtained by the first 1000 days program in the Payangan Sub-District, Bali Province. This research was a descriptive study using secondary data sourced from the survey of the Community Oriented Medical Education 1000 Days Early Life education program conducted by FKIK Warmadewa University. The research subjects were pregnant women who lived in the Payangan sub-Sub-District, Gianyar Regency, Bali in 2019-2020. The total number of subjects in this study were 110 people. The data collected consisted of data on demographic characteristics, pregnancy, childbirth, and diet. Of 110 Pregnant women in Payangan Sub-District in 2019-2020, 48% showed an average normal body mass index, most (76%) pregnant women in this region had no history of disease and high and very high-risk pregnancy was found in 61% of the subjects. The diet, environment and family APGAR mostly were considered good, namely in 86%, 72%, and 100% respectively. Most deliveries were by cesarean section, i.e., 59% and most did not have delivery complications (85%).
CRITICAL VALUE OF GLUCOSE USING CRITIVA 1.0 APPLICATION IN BALI MANDARA EYE HOSPITAL Pande Putu Ayu Patria Dewi; Dewa Putu Yudhi Ardhiana; I Dewa Putu Gede Wiyata Putra
JURNAL WIDYA MEDIKA Vol. 9 No. 1 (2023): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v9i1.4147

Abstract

Critical value is very critical result in laboratory examination that can indication several emergency conditions. Reporting critical values are controversial between hospital management, clinicians, and laboratory. Reporting critical value required effective communication. Information technology has become one of the solution effective communication in reporting critical values. Critical values can occur in clinical chemistry, hematology, and other laboratory examination. Glucose is one of the clinical chemistry parameters which is often foound critical value and therapy must be given immediately. Aim of this research is to evaluated time reporting using Critiva 1.0 application in cellular phone of clinical pathologist Bali Mandara Eye Hospital. Samples were 50 times reporting the glucose critical value simulation using the Critiva 1.0 application and 50 times reporting the Standard Operating Operations (SPO) simulation at the Bali Mandara Eye Hospital. Simulation carried by laboratory techonology in charge. We used means to analyze time reporting and SPSS version 16. Mean reporting glucose critical value using Critiva 1.0 application was 12 seconds. Mean reporting glucose critical value using SPO Bali Mandara Eye Hospital was 720 seconds.
HYPOGLYCEMIC, ANTI-INFLAMMATORY EFFECT OF PORANG (AMORPHOPHALLUS ONCHOPYLLUS) ON ALLOXAN-INDUCED DIABETIC RATS Young, Andre; Novita, Bernadette Dian; Ricardo, Evan; Dewi, I.G.A.P.D; Amadeo, Jovan; Dewi, Sianty; Tahalele, Paul
JURNAL WIDYA MEDIKA Vol. 9 No. 1 (2023): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v9i1.4173

Abstract

Introduction: Iles-iles / Porang is a tuber-producing plant that is commonly found in Indonesia. One of the most sought after content from Porang is Glucomannan. One of Porang’s health benefit is related to the effect of lowering blood glucose levels because it can prevent glucose absorption. These benefit is interesting to study because there has been no research linking the use of Porang to reduce inflammatory process in hyperglycmic conditions. Purpose: This study aims to analyze the anti-inflammatory, anti-oxidant and hypoglycemis effects of Glucomannan from Porang (Amorphophallus onchophyllus) extract in experimental animals. Method: The research design was a true experimental post-test only control group with random sampling to determine 5 white rats into the normal group, positive control group, negative control group and treatment 1, 2 and 3. The positive control group received Acarbose therapy thile the negative control group received carboxy-methyl-cellulose (CMC) therapy. This study used Porang extract (Amorphophallus onchophyllus) with concentrations of 200, 400 and 800 mg/Kg in hyperglycemic white rats that had been induced by Aloxan. The study was conducte for 50 days and then blood and serum samples were taken to assess the effect of hypoglycemia, anti-inflammatory and anti-oxidant using blood glucose, Malondialdehyde and C-reactiveprotein (CRP) measurement. Result and Discussion: The results showed no significant difference between the groups of rats receiving Porang extract and the positive and negative control groups. However, the MDA levels after 50 days of intervention between the negative control group and the therapy with doses of 200, 400 and 800 mg/Kg showed significant differences. Similarly found for blood glucose levels after intervention between negative control group and the 200 and 400 mg/Kg therapy group. This results may be caused by the type of Porang used, the form of the Porang and the concentration level of the Porang extract. Conclusion: Porang with the type of Amorphophallus onchophyllus can’t be used directly, but requires further processing to obtain the active substance Glucomannan.
CORRELATION OF SERUM ZINC LEVELS WITH SEVERITY AND DISEASE ACTIVITY IN VITILIGO PATIENTS AT SANJIWANI GIANYAR HOSPITAL Sayu Widiawati; Made Budiani; Pradnya Iswara
JURNAL WIDYA MEDIKA Vol. 9 No. 1 (2023): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v9i1.4230

Abstract

Vitiligo is autoimmune disease, characterized by well defined milky-white macule, caused by destruction of melanocyte selectively. Management of vitiligo is still challenging due to the pathogenesis is not yet fully understood, and vitiligo can caused significant psychological distress to the patients. Several studies reveal the role of zinc as an important element in the prevention and treatment of vitiligo based on zinc's function as an antiapoptotic, as a bull against free radicals, and as an important element in melanogenesis by stimulating cell mediated immunity activity, zinc and alpha melanocyte stimulating hormone. We conducted an analytical cross-sectional study that aims to determine the correlation between plasma zinc levels and the severity of vitiligo using the VASI score and vitiligo disease activity calculated based on the VIDA score. The results showed that there was a strong negative correlation between serum zinc levels and the VASI score, with a correlation coefficient or r = -0.668 and p
THROUGH A MICROSCOPIC LENS: SKIN MICROBIOME AS THE CONFEDERATE IN ATOPIC DERMATITIS Catharina Clarissa Ursia; Patricia Dian Putri
JURNAL WIDYA MEDIKA Vol. 9 No. 1 (2023): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v9i1.4265

Abstract

Reciprocity between skin microbiome and the host underlies the occurrence, exacerbation, and severity of atopic dermatitis (AD). However, the role of skin microbiome in the pathogenesis of AD is yet to be depicted. This review highlights the host–microbiome interactions which relies on barrier status, microbiome composition, and microbe–microbe interactions. A microbiome shift, with abundance of S. aureus and lower microbial diversity, compromises the skin barrier function. It goes to show that epidermal barrier defect depletes the protective commensal skin bacteria and demonstrate how dysbiosis of the skin microbiome can lead to AD.
GRAVES DISEASE Prettysun Ang Mellow
JURNAL WIDYA MEDIKA Vol. 9 No. 1 (2023): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v9i1.4510

Abstract

Graves' disease is one of the most common autoimmune diseases. The disease is named after the scientist Robert James Graves, who first described it in the 19th century as a syndrome with an enlarged and overactive thyroid gland (hyperthyroidism due to circulating autoantibodies), rapid heart rate, and eye abnormalities. graves’ disease is the most common cause of hyperthyroidism and affects more women than men. Graves’ disease can appear at any age, but it most commonly appears for the first time between the ages of 20 and 40. Factor is a predisposition that is more dominant than environmental factors. There are circulating autoantibodies produced by B lymphocytes induced by autoreactive T lymphocytes that recognize thyrotropin-stimulating hormone (TSH) receptors in thyroid tissue as self-antigens. These autoantibodies are also known as TSH receptor antibodies (TSH-R Ab), thyrotropin stimulating antibodies (TSI), or thyrotropin receptor antibodies (TRAb). TRAb acts like TSH to cause thyroid hyperplasia (diffuse goitre), increased synthesis, and excessive and uncontrolled secretion of thyroid hormones (T4: tetraiodothyronine T4 and T3: triiodothyronine T3). Investigations to confirm Graves’ disease show elevated thyroid hormones (T4 and T3) with very low TSH and increased TRAb. On thyroid ultrasound, the majority of patients have a hypervascular and hypoechoic diffusely enlarged thyroid gland. The treatment for graves’ disease is to reduce the synthesis of thyroid hormones using anti-thyroid drugs, or to reduce the amount of thyroid tissue with radioactive iodine (RAI) or total thyroidectomy. Methimazole is the first-choice antithyroid drug with good effectiveness and safety. Although the recurrence rate after stopping the drug is still quite high
REPORTING THE DETECTION RESULT OF SARS-CoV-2 ANTIBODY RAPID TEST OF COMPANY’S EMPLOYEES IN SURABAYA AND PASURUAN, INDONESIA Mulya Dinata; Angelina Tulus; Evelyn Ongkodjodjo; Lukas Slamet Rihadi; Dewa Ayu Liona Dewi; Gabrielle Tjipta Joewana; Nurlita Wulansari
JURNAL WIDYA MEDIKA Vol. 9 No. 1 (2023): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v9i1.4631

Abstract

Background: Coronavirus (CoV) is a large family of viruses that causes illnesses ranging from mild to severe symptoms. Coronavirus Disease (Covid-19) is a new type of virus that has never been indentified in humans before. Methods: All antibody test methods and RT-PCR tests have an optimum time window in the incubation period or infection of a person. The antibody test method cannot be used as an early detection tool for people who are still on the first day of the incubation process. IgG and IgM antibody levels are still low on the first day of infection, even though the number of viral particles is very high at the beginning. Result: Sars-Cov-2 (Covid-19) antibody examination sample was taken from Main Clinic of Sentra Medika Surabaya, from May to August 2020, with the age range of 18-65 old amounted to 1015 people. The number of samples with the age range of 40-49 is 404 people (39,90%), Production Department has 773 samples of people (76,16%), the number of security samples is 39 people (3,84%), and others have 109 samples of people (10,74%). The number of male samples is 666 people (65,62%) more than female 349 people (34,38%). Positive Covid-19 Antibody examination results for Office Department are IgM 3 people, IgG 3 people, and the total numbers are 6 people (21%). Positive Covid-19 Antibody examination results for the production department are IgM 14 people, IgG 1 person. So, the total numbers are 17 people (59%). The most positive Covid-19 antibody examination result is the production department namely 59% and including positive results for IgM and IgG. The condition above the production department has the most frequent because of the condition of employees including some companies which had overtime work or 2 shifts. Conclusion: The highest number of Positive Covid-19 antibody examination result. The most department is the production department. The age range of 50-59 years old has a small number. At the time of being infected with Covid-19, IgG and IgM are negative, it needs time to get a positive examination result of IgG or IgM or both. The antibody examination method cannot be used as an early detection tool for Covid-19.

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