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Cermin Dunia Kedokteran
Published by PT. Kalbe Farma Tbk.
ISSN : 0125913X     EISSN : 25032720     DOI : 10.55175
Core Subject : Health,
Health Professions
Cermin Dunia Kedokteran (CDK) is a Medical Journal published since 1974 and affiliated with PT Kalbe Farma Tbk. CDK is intended to help accommodate scientific publications and help increase and disseminate knowledge related to the development of medical science, pharmacy, and public health. CDK covers the disciplines of medicine, pharmacy, and health with several types of articles, namely: 1. Research 2. Literature review 3. Case report 4. Evidence-based case report (EBCR), systematic review 5. Other scientific articles Based on the SK Kemendikbudristek Nomor 152/E/KPT/2023, CDK has obtained Rank 4 (SINTA 4) for Scientific Journals.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 1,312 Documents
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Nutrisi Enteral Jangka Pendek Tinggi Serat, Khusus Diabetes pada Pasien Lanjut Usia dengan Diabetes Melitus Tipe 2 – Laporan Kasus: Laporan Kasus Simatupang, Yustina Rossa; Wangsa, Andrean; Nareswara, Anastu Regita; Setiyaningrum, Melinda; Putra, Dendy Daffa Anugrah
Cermin Dunia Kedokteran Vol 53 No 03 (2026): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i03.2069

Abstract

Introduction: High-fiber diabetes-specific formulas (DSFs) are designed to support glycemic control in patients with type 2 diabetes mellitus (T2DM), particularly those requiring nutritional support. Despite their potential benefits, evidence regarding their short-term effects on blood glucose levels and insulin requirements remains limited. This case report explores the impact of an oral DSF on glycemic control in an elderly patient with T2DM over a four-day inpatient period. Case: A 70-year-old overweight woman (BMI 24.6 kg/m²) was hospitalized due touncontrolled hyperglycemia (HbA1c 10.6%, fasting glucose 469 mg/dL) with poor oral intake (< 50% of needs) secondary to nausea and vomiting. A standardized DSF was administered orally alongside a diabetic soft diet for 4 days. DSF was introduced at 150 mL three times daily and titrated to 200 mL twice daily, contributing to a total intake of approximately 1,500 kcal/day. Insulin doses (10 IU regular insulin three times a day) remained unchanged. Monitoring included daily fasting glucose and clinical tolerance. Fasting blood glucose decreased from 469 mg/dL on day 1 to 260 mg/dL by day 4. The patient showed improved oral intake (up to 75% of caloric needs) and better appetite without gastrointestinal complaints. No hypoglycemia episodes or insulin dose adjustments were necessary. Discussion: During the four-day observation period, fasting blood glucose decreased progressively from 469 mg/dL to 260 mg/dL without modification of insulin dosage. Oral intake improved to approximately 75% of estimated needs, and no hypoglycemic episodes or gastrointestinal intolerance were observed. The improvement in glycemic trends occurred alongside structured nutritional support and consistent insulin therapy. Conclusion: Short-term administration of a high-fiber DSF improved glycemic trends and nutritional intake in an elderly T2DM patient without adverse effects. DSF can be an effective adjunct in individualized medical nutrition therapy to support glycemic stabilization during hospitalization.
Peran Suplementasi AREDS2 dalam Menurunkan Progresivitas Age-related Macular Degeneration: Tinjauan Pustaka Valencia, Jessica; Pangputri, Floretta Dwinovi
Cermin Dunia Kedokteran Vol 53 No 03 (2026): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i03.2135

Abstract

Age-related macular degeneration (AMD) merupakan penyakit degeneratif makula yang menjadi penyebab utama hilangnya penglihatan irreversible pada lanjut usia di negara maju. Prevalensi AMD di populasi Asia sebesar 6,8% untuk AMD tahap awal dan 0,56% untuk AMD tahap lanjut. Peningkatan produksi reactive oxygen species (ROS) yang tidak dapat diimbangi oleh sistem antioksidan di retina menyebabkan kerusakan struktural lapisan epitel pigmen retina (EPR). Kerusakan ini mengakibatkan disfungsi sel EPR, akumulasi drusen, dan progresivitas penyakit menuju tahap lanjut. Suplementasi antioksidan seperti formulasi AREDS2 merupakan pilihan terapi yang dapat menurunkan progresivitas AMD dari tahap menengah ke tahap lanjut. Formulasi AREDS2 terdiri dari lutein, zeaxanthin, vitamin C, vitamin E, zinc, dan copper yang bekerja melalui berbagai mekanisme untuk melindungi retina dari stres oksidatif, menghambat inflamasi, dan memperbaiki fungsi seluler. Tinjauan pustaka ini mengulas peran suplementasi AREDS2 dalam AMD beserta mekanisme kerja masing-masing komponennya dalam menurunkan progresivitas penyakit dan mempertahankan fungsi penglihatan pada pasien lanjut usia

Page 132 of 132 | Total Record : 1312

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