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Journal of Dental and Biosciences
Published by Universitas Jenderal Soedirman
ISSN : -     EISSN : 30892619     DOI : https://doi.org/10.20884/1.jdentbios.2025.2.01.12
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Public Health
Journal of Dental and Biosciences (JDB), is a publication of scientific writings related to dentistry and other biosciences fields in efforts to diagnose, prevent, treat oral diseases, and improve oral health. The spread of dental fields comprises pediatric dentistry, conservative dentistry, endodontics, periodontics, prosthodontics, orthodontics, oral and maxillofacial surgery, oral medicine and pathology, community dentistry, dental material science and technology, oral biology, biomolecular dentistry, oral and maxillofacial radiology, and forensic odontology.
Arjuna Subject : Kedokteran Gigi - Perawatan Gigi
Articles 36 Documents
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The activity of saga leaf (Abrus precatorius) ethanol extract fractions on biofilm degradation of Fusobacterium nucleatum Satya Maharani br. Simatupang; Fanni Kusuma Djati; Meylida Ichsyani; Eka Prasasti Nur Rachmani; Maulina Triani
Journal of Dental and Biosciences Vol 3 No 02 (2026): Journal of Dental and Biosciences
Publisher : Jurusan Kedokteran Gigi Fakultas Kedoketaran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jdentbios.2026.3.02.14766

Abstract

Periodontitis is a chronic inflammatory disease causing permanent destruction of periodontal tissues. Fusobacterium nucleatum is a key bacterium involved in periodontitis biofilm formation. Biofilm degradation is crucial for periodontitis treatment. This study aimed to investigate the antibiofilm activity of ethanol extract fractions from Abrus precatorius leaves against F. Nucleatum. An in vitro experimental study was conducted using nine treatment groups, consisting of three fractions (n-hexane, ethyl acetate, and residual) at three concentrations (3.125, 6.25, and 12.5 mg/mL). Chlorhexidine gluconate 0.2% and metronidazole served as positive controls, while 1% DMSO was used as a negative control. Biofilm degradation was assessed using microtiter plate assay with crystal violet 1% staining and Microplate Reader at 600 nm. Data analysis employed one-way and two-way ANOVA, followed by post-hoc LSD and Tukey HSD tests. Results showed that all fractions at various concentrations effectively degraded biofilm (p≤0,05) compared to the negative control, except for the residual fraction at 3,125 mg/mL. Two-way ANOVA revealed significant differences between concentrations and fractions. The n-hexane fraction at 3.125 mg/mL demonstrated the highest biofilm degradation efficacy, comparable to chlorhexidine gluconate 0.2%. This study concludes that Abrus precatorius leaf ethanol extract fractions exhibit antibiofilm activity against F. Nucleatum.
Traditional oral health practices and sociocultural determinants influencing oral healthcare seeking among pre-elderly and older adults: A qualitative study at the Cilongok 1 community health center Fitri Diah Oktadewi; Adinda Salsabila Yulindra Arvin; Barto Lumeus Felix Tampubolon; Bintang Arzaq Ramadhan Putra Taufik; Dwike Luthfiyahul Ahmalina; Insania Ridha Dhiyasary; Salsabil Rasya; Shofiyya Shofiyya; Kamila Khelwa Zahrojannah; Zaiim Husni Mubarok
Journal of Dental and Biosciences Vol 3 No 02 (2026): Journal of Dental and Biosciences
Publisher : Jurusan Kedokteran Gigi Fakultas Kedoketaran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jdentbios.2026.3.02.19672

Abstract

Many people in Cilongok District, especially in the area of ​​Puskesmas I Cilongok, still use traditional medicine and self-medication to treat dental and oral complaints. This is influenced by limited knowledge, socio-cultural factors, and belief in traditional medicine. This study used a qualitative method with a semi-structured interview technique with 7 respondents who were receiving health services at Puskesmas I Cilongok. The sampling technique was purposive sampling to obtain relevant data. The results showed that some people still use traditional ingredients such as siwak, pepper, papaya sap, ash, and gending as natural remedies, while others have switched to modern methods. Factors that influence this behavior include cultural and religious beliefs, personal experience, access to health workers, economic conditions, and the influence of social media. The Cilongok community still maintains traditional medicine that is influenced by socio-cultural factors and local beliefs. Culture-based health education is needed to improve understanding and behavior of more appropriate dental care and encourage trust in professional health services
Management of generalized stage III grade C periodontitis with extracoronal wire splinting and gingival curettage: A case report Mutia Rochmawati; Nur ‘Aini Dewi Shafitri; Syerihan Syerihan
Journal of Dental and Biosciences Vol 3 No 02 (2026): Journal of Dental and Biosciences
Publisher : Jurusan Kedokteran Gigi Fakultas Kedoketaran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jdentbios.2026.3.02.20188

Abstract

Periodontitis is an inflammatory disease of the periodontal tissues that leads to attachment loss and tooth mobility, thus requiring comprehensive management. Periodontal therapy is initiated with non-surgical treatment aimed at controlling bacterial infection, reducing inflammation, and preventing the progression of periodontal tissue destruction through scaling and root planing. Teeth with mobility can be managed with extracoronal splinting to improve stability, while persistent inflammation within periodontal pockets may require curettage as a surgical therapy to eliminate granulation tissue. A 42-year-old female presented with complaints of mobility in the mandibular anterior teeth and gingival recession. Clinical examination revealed grade 1–2 tooth mobility, probing depths of 1–5 mm, positive bleeding on probing, and clinical attachment loss of 3–8 mm. Radiographic examination showed that there was alveolar bone resorption that extended to the middle 1/3 of the root. The diagnosis was established as generalized periodontitis stage III grade C based on the greatest interdental CAL of 8 mm on tooth 31, alveolar bone resorption up to the middle third of the root, and the bone loss percentage to age ratio of 50%/42 years, which is 1.19 (>1.0), according to the 2018 periodontal disease classification criteria. Treatment was performed in stages, including scaling and root planing, followed by extracoronal wire splinting on teeth 33–43 for stabilization, and periodontal curettage to eliminate residual inflamed tissue. Evaluation at 1 month showed reduced tooth mobility, improvement in gingival condition, and reduction in probing depth to 1–3 mm. A staged treatment approach for Stage III Grade C periodontitis in this case demonstrated short-term clinical improvement, although long-term follow-up is required to evaluate the stability of treatment outcomes.
Severity and location of root dilaceration in permanent maxillary anterior and premolar teeth on panoramic radiographs Firzana Nurul Izza Taufik; Haris Budi Widodo; Mahindra Awwaludin Romdlon; Irfan Dwiandhono; Rinawati Satrio
Journal of Dental and Biosciences Vol 3 No 02 (2026): Journal of Dental and Biosciences
Publisher : Jurusan Kedokteran Gigi Fakultas Kedoketaran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jdentbios.2026.3.02.21654

Abstract

Background. Root dilaceration is an anatomical variation characterized by a sharp angulation of the tooth root that may complicate diagnosis and influence treatment planning, particularly in endodontic and surgical procedures. Objective. To analyze the severity and location of root dilaceration in permanent maxillary anterior and premolar teeth on panoramic radiographs. Methods. A retrospective analytical cross-sectional study was conducted using 224 permanent maxillary teeth with root dilaceration identified on panoramic radiographs. Dilaceration severity was categorized as mild, moderate, or severe, while the location of root curvature was classified into coronal, middle, or apical thirds. Statistical analysis was performed using the Kruskal–Wallis test followed by the Mann–Whitney U test for severity comparison, and the Chi-Square test for distribution of curvature location. Result. Mild root dilaceration was the predominant finding (78.1%) and was mainly located in the apical third (64.3%). Significant differences were observed in both the degree and anatomical location of root dilaceration among maxillary lateral incisors, canines, first premolars, and second premolars (p < 0.001). Maxillary lateral incisors exhibited significantly greater curvature severity than the other tooth groups, whereas canines and premolars predominantly showed mild dilaceration. Conclusion. Significant differences were observed in both the degree and location of root dilaceration among permanent maxillary anterior and premolar teeth, with mild dilaceration predominantly located in the apical third. Maxillary lateral incisors exhibited the greatest morphological variation, followed by canines and premolars.
Effect of topical Apis trigona honey on FGF-2 expression, fibroblast, and capillary blood vessel counts in post-extraction wound healing Anita Dyah Septiani; Haris Budi Widodo; Helmi Hirawan; Ali Taqwim
Journal of Dental and Biosciences Vol 3 No 02 (2026): Journal of Dental and Biosciences
Publisher : Jurusan Kedokteran Gigi Fakultas Kedoketaran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jdentbios.2026.3.02.21671

Abstract

Background: Tooth extraction causes a wound in the tooth socket that may lead to complications and delayed healing. The acceleration of wound healing can be observed through fibroblast growth factor-2 (FGF-2) expression, the number of fibroblasts, and the number of capillary blood vessels. Trigona honey, produced by the stingless bee Apis trigona, contains flavonoids with antibacterial and antioxidant properties and is traditionally used to support healing. This study aimed to determine the effect of topical Apis trigona honey on FGF-2 expression, fibroblast count, and capillary blood vessel count in post-extraction wound healing. Methods: This laboratory experimental study used 32 male guinea pigs (Cavia porcellus) divided into a control group (n=16) and a treatment group (n=16). Following incisor extraction, the treatment group received 0.5 mL of topical Apis trigona honey, while the control group received sterile distilled water only. On day three, the animals were sacrificed and mandibular tissue was harvested. FGF-2 expression was assessed by immunohistochemistry, while fibroblast and capillary blood vessel counts were assessed with haematoxylin-eosin staining. Data were analysed using an independent t-test (95% confidence interval, p<0.05). Results: FGF-2 expression did not differ significantly between the control and treatment groups (p=0.078). However, the treatment group showed significantly higher fibroblast counts (p<0.001) and capillary blood vessel counts (p<0.001) compared with the control group. Conclusion: Topical application of Apis trigona honey did not increase FGF-2 expression but significantly increased fibroblast and capillary blood vessel counts, suggesting its potential as a supportive agent in post-extraction wound healing.
Javanese turmeric (Curcuma xanthorrhiza Roxb.) as a candidate for adjuvant therapy for periodontitis: A review of antibacterial, anti-inflammatory, and osteoprotective activities Andrina Nauralisa; Dewi Setyowati; Diarra Fathiya Azka; Kesye Yulia Margaretha; Kezia Budiman; Dwi Nur Indah Sari
Journal of Dental and Biosciences Vol 3 No 02 (2026): Journal of Dental and Biosciences
Publisher : Jurusan Kedokteran Gigi Fakultas Kedoketaran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jdentbios.2026.3.02.21743

Abstract

Latar Belakang: Periodontitis merupakan penyakit inflamasi kronis multifaktorial yang ditandai destruksi progresif jaringan penyangga gigi akibat interaksi biofilm subgingiva dan respons imun pejamu. Scaling and root planing sebagai terapi baku memiliki efektivitas terbatas pada kondisi klinis tertentu, sedangkan penggunaan antibiotik adjuvan terkendala resistensi antimikroba. Temulawak (Curcuma xanthorrhiza Roxb.) mengandung xanthorrhizol dan kurkuminoid yang bersifat antibakteri, antiinflamasi, dan berpotensi osteoprotektif. Tujuan dari penelitian ini adalah untuk mengevaluasi potensi C. xanthorrhiza sebagai kandidat terapi adjuvan periodontitis. Metode: Tinjauan pustaka disusun mengikuti panduan PRISMA melalui penelusuran Connected Papers, Google Scholar, PubMed, dan Semantic Scholar. Kriteria inklusi meliputi artikel penelitian asli sepuluh tahun terakhir yang tersedia sebagai free full text dan relevan dengan topik. Dari 1.531 artikel teridentifikasi, 13 artikel memenuhi kriteria dan dianalisis. Hasil: Penelitian in vitro dan in vivo menunjukkan tiga mekanisme utama. Xanthorrhizol memiliki aktivitas antibakteri terhadap Porphyromonas gingivalis, Fusobacterium nucleatum, Aggregatibacter actinomycetemcomitans, dan Streptococcus sanguinis serta menghambat pembentukan biofilm. Xanthorrhizol dan kurkuminoid menekan mediator proinflamasi, sedangkan beberapa penelitian menunjukkan penghambatan resorpsi tulang alveolar dan regulasi remodeling tulang. Simpulan: C. xanthorrhiza berpotensi sebagai terapi adjuvan periodontitis, namun uji klinis berdesain kuat masih diperlukan untuk memastikan efektivitas dan keamanannya

Page 4 of 4 | Total Record : 36

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