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INDONESIA
Jurnal Kedokteran Methodist
Published by Universitas Methodist Indonesia
ISSN : 26847132     EISSN : 26847132     DOI : DOI: https://doi.org/10.46880/jkm.v20i1
Core Subject : Health, Science, Education, Agriculture, Social,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary Other
Jurnal Kedokteran Methodist (JKM) is a peer-reviewed, open-access journal that welcomes manuscripts in basic and clinical research, encompassing all aspects of medicine, health sciences, and pharmacy. Reports on genomics, epigenetics, and stem cells are welcome as well. The journal covers original research articles, case reports, and review articles.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 79 Documents
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A Case of Complete Recovery From Recurrent Bell’s Palsy After Peripheral Blood Stem Cell Transplantation : A Case of Complete Recovery From Recurrent Bell’s Palsy After Peripheral Blood Stem Cell Transplantation lim, hadyanto; Hutasoit, Eka Samuel P; Endy Juli Anto
Jurnal Kedokteran Methodist Vol. 17 No. 1 (2024): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v17i1.2812

Abstract

Background Recurrent Bell’s palsy is a rare condition that can affect the ipsilateral or contralateral to the affected side of the primary attack. There is still no consensus on treatment guidelines for recurrent Bell’s palsy. Therefore, we report a case of idiopathic recurrent contralateral facial palsy treated with autologous peripheral blood stem cell (PBSC) transplantation. Case Presentation A 72-year-old man presented with the sudden onset of right facial weakness, which was contralateral to the affected side of the first episode of facial palsy. The weakness had progressed with difficulty in closing the right eye, drooling the water from the right side of the mouth, and chewing impairment which was consistent with House Brackmann grade IV or moderately severe facial nerve grading system. He had exposure to cold stimulation, and a history of hypertension. He was given G-CSF 10 ug/kg/day for 5 days to mobilize stem cells, followed by apheresis on the 5th day. He did not receive acupuncture treatment. He had a complete recovery in 3 weeks with House Brackmann grade I or normal function of facial nerve. Conclusion Peripheral blood stem cell transplantation had a beneficial effect on the complete recovery of this recurrent Bell’s palsy and provides a treatment strategy in patients with unilateral facial palsy.
A ANTIBODY MEDIATED IMMUNITY: ANTIBODY MEDIATED IMMUNITY Sembiring, Budi Darmanta
Jurnal Kedokteran Methodist Vol. 17 No. 1 (2024): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v17i1.2897

Abstract

Keeping the integrity and the individual balance needed an adequate immunity system. Therefore the immunity mechanism to the dangerous antigen consists of physical immunity and chemical, symbiosis with a normal flora bacteria, innate immunity with a specific immunity which is got, consist of humoral immunity and cell immunity (cell-mediated immunity). The antibody is the component of immunity that is gotten which protects the body from microorganism infection and the product which is toxic. Because of that, the interaction between antigen and antibody is very important and much used in vitro for diagnostic purposes. The use of this reaction in vitro between antigen-antibody is called serology.
A TERAPI METHOTREXATE PADA PENDERITA PSORIASIS VULGARIS: TERAPI METHOTREXATE PADA PENDERITA PSORIASIS VULGARIS Tarigan, Juliyanti; Simanjuntak, Evirosa; Marpaung, Alexander P.
Jurnal Kedokteran Methodist Vol. 17 No. 1 (2024): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v19i1.2898

Abstract

Psoriasis merupakan penyakit peradangan kronik pada kulit berupa perubahan pertumbuhan dan diferensiasi epidermis, serta abnormalitas biokimiawi, imunologik, dan vaskular. Psoriasis dapat bermanifestasi pada kulit, kuku, dan persendian. Diagnosis psoriasis biasanya ditegakkan berdasarkan anamnesis dan gambaran klinis lesi kulit. Pada kasus-kasus tertentu, dibutuhkan pemeriksaan penunjang seperti pemeriksaan biopsi histopatologi dan pemeriksaan              laboratorium.                                   Secara histopatologi akan tampak akantosis, parakeratosis, elongasi rete ridge. Tampak neutrofil dan limfosit yang bermigrasi membentuk mikroabses Munro. Pada dermis akan tampak tanda-tanda inflamasi seperti hipervaskularitas dan dilatasi serta edema papila dermis. Pemeriksaan laboratorium pada psoriasis bersifat tidak spesifik. Pengobatan anti psoriasis berspektrum luas baik secara topikal maupun sistemik telah tersedia. Sebagian besar obat-obatan ini bekerja sebagai imunomodulator. Sebelum memilih regimen pengobatan, penting untuk menilai perluasan serta derajat keparahan psoriasis. Salah satu cara yang paling sering digunakan untuk menilai derajat keparahan psoriasis adalah dengan menghitung skor Psoriasis Area and Severity Index (PASI).
A HUBUNGAN NILAI ALBUMIN SERUM DENGAN TINGKAT KEPARAHAN DAN LAMA RAWATAN PASIEN DM TIPE 2 DENGAN COVID-19 DI RSU BINA KASIH: HUBUNGAN NILAI ALBUMIN SERUM DENGAN TINGKAT KEPARAHAN DAN LAMA RAWATAN PASIEN DM TIPE 2 DENGAN COVID-19 DI RSU BINA KASIH Tarigan, M.Bastanta; Situmorang, Nasib Mangoloi; Hutahaean, Reinhard
Jurnal Kedokteran Methodist Vol. 17 No. 1 (2024): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v17i1.2900

Abstract

Introduction Coronavirus disease 2019 (COVID-19) is an infectious disease that affects the respiratory system caused by Severe Acute Respiratory Syndrome Coronavirus (SARS-COV-2), which has become a health problem in Indonesia. The duration of treatment and the severity of COVID-19 will increase the risk of death and significant costs, which undoubtedly burden patients and the country. A marker is needed to determine the severity of the disease and the duration of treatment for COVID-19 patients with diabetes. Albumin is a protein that plays anti-inflammatory, antioxidant, anti-infection roles, and also participates in drug transfer within the human body. Poor glucose control, insulin resistance, insulin deficiency in type 2 diabetes (type 2 DM), and viral load in COVID-19 lead to hypoalbuminemia. Hypoalbuminemia will disrupt its function, leading to increased inflammation, oxidative stress, infection, and disturbance in drug distribution, thus hypoalbuminemia is suspected to play a role in increasing the severity and duration of treatment in type 2 DM patients with COVID-19. Method This study is an observational analytical study with a cross-sectional design conducted at Bina Kasih Medan General Hospital. The research subjects were type 2 DM patients infected with COVID-19 who underwent inpatient care from August to October 2021 with consecutive sampling that met the inclusion and exclusion criteria. Patients were categorized into moderate and severe severity levels. The duration of treatment was divided into less than and greater than or equal to 11 days, and serum albumin levels were evaluated. The independent variable was albumin, and the severity level and duration of treatment were dependent variables. The data used were secondary data from medical records, and bivariate analysis was performed to see the relationship between independent and dependent variables using the Chi-Chisqure test. Results During the period from August to October 2021, 82 subjects with type 2 DM who were infected with COVID-19 and underwent inpatient care were obtained. Out of 82 subjects who met the inclusion criteria, 34 subjects were included. Of the 34 study subjects, the majority were male, namely 26 subjects (76.4%), and 8 subjects (23.5%). Subjects who underwent inpatient care for <11 days were 15 (44.1%) and those who underwent inpatient care ≥11 days were 19 (55.9%). 18 subjects (52%) had moderate severity levels, and 16 subjects (47.05%) had severe severity levels. Based on the results of bivariate analysis, there was an inverse relationship between serum albumin levels and the severity of the disease (P <0.032), but there was no significant relationship between albumin levels and the duration of hospitalization (P <0.350). Conclusion A decrease in albumin levels is associated with the severity of the disease but not with the duration of treatment.
Gambaran Tingkat Pengetahuan Orang Tua tentang Demam Berdarah Dengue (DBD) Zendrato, Wira Setyawati; Saing, Bistok; Riau, Wilson
Jurnal Kedokteran Methodist Vol. 17 No. 2 (2024): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v17i2.517

Abstract

Background: Dengue Hemorrhagic Fever (DHF) is one of the most common public health problems in Indonesia. Dengue Hemorrhagic Fever is an infectious disease caused by dengue virus. In 2015, there were recorded 126,675 DHF patients in 34 provinces in Indonesia, and 1,229 of them died. The number is higher than the previous year, which is as many as 100,347 people with DHF and as many as 907 patients died in 2014. Method: This research is a descriptive study with a large sample of 95 respondents with the location of research in Merdeka Village, Medan New District, Medan City. The study began on June 22 - July 04, 2017 and data was collected through the distribution that have validation. Results: The results showed that of the 95 respondents, majority 40 people (42.1%), had sufficient knowledge about Dengue Hemorrhagic Fever (DBD), 37 people (42.1%), had good knowledge about DBD and 18 people (18.9%)had less knowledge about DBD. Conclusion: Based on this research, it can be concluded that generally levelof parent knowledge about DBD including enough category. Parents who have a good knowledge of the source of information from health workers counseling.
Gambaran Diagnostik Dan Penatalaksanaan Pasien Penyakit Paru Obstruksi Kronik Kaur, Balraj; Parhusip, Rudolf S.; Sinurat, Puji Pinta O.
Jurnal Kedokteran Methodist Vol. 17 No. 2 (2024): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v17i2.518

Abstract

Background: World Health Organization (WHO), Indicate in 1990 occupy 6th order as the leading cause of death and will occupy 3rd order after cardiovascular disease and cancer.In Indonesia estimated 4,8 million patients with prevalence 5,6%. Method: This research was conducted by using descriptive research design with cross sectionall approach. The number of samples is 80 people withsimple random sampling technique. Results: Based on the result of research from 80 samples of patients obtained most age ≥60 years ie 50 patients (62,5%),the most of gender is male 69 patient (86,3%),the most of clinical symptoms is shortness of breath 42 patient (52,5%),the most of smokers status is active smoker 58 patient (72,5%), the most of job is entrepreneur 30 patient (37,5%),the most of examination support is radiology 50 patient (62,5%), the most of management is bronchodilator 35 patient (43,7%) and the most of mortality rate was in the ICU room 5 patient (50%). Conclusion: The result showed with Chronic Obstructive Pulmonal Disease the most treated was male patiens with age ≥65 years, the most of job is entrepreneur, which have a history of smoking with clinical symptoms of shortness breath and cough phlegm, the most of used examintaion support is radiology and the most of management is bronchodilator. Choronic Obstructve Pulmonal Disease management is excellent with fewer deaths.
Tingkat Pengetahuan, Sikap Dan Tindakan Siswa-Siswi Sekolah Menengah Atas Terhadap Acquired-Immunodeficiency Syndrome Angel, Pretty; Nababan, Kristo A.; Hutasoit, Eka Samuel P.
Jurnal Kedokteran Methodist Vol. 17 No. 2 (2024): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v17i2.533

Abstract

Background: The problem of HIV/AIDS is a major problem that threatens Indonesia and many other countries around the world. Currently there is not any country free from HIV/AIDS. Since the beginning of the HIV/AIDS became epidemic, nearly 78 million people in all over the world have been infected with HIV and about 39 million people have died from HIV. WHO estimates that 0,8% of people worldwide aged 15-49 years live with HIV. Method: The purpose of this study is to determine the level of knowledge, attitude, and action in SMA Negeri 1 Kabanjahe against AIDS. This research uses descriptive method with cross sectional approach. Samples are students of class X & XI IPA counted 136 people with slovin formula, where respondents obtained by using simple random sampling technique. Data collection uses questionnaires. Results: The result of the research indicates that knowledge is good as 87 people (64,0%), with female respondents has good knowledge level of 45 people (33,1%), and based on the most source of information is school as many as 60 people (44,1%). The result of attitude test is good as many as 78 people (57,4%) and result of action test is enough counted 69 people (50,7%). Conclusion: Based on this research can be concluded that students of class X & XI IPA in SMA Negeri 1 Kabanjahe have knowledge level, good attitude and enough action against AIDS.
PENGARUH HIPERKOLESTROLEMIA TERHADAP FUNGSI KOGNITIF PADA PASIEN LANSIA DI PUSKESMAS SIMALINGKAR MEDAN T.Rumapea, Febrin; Siagian, Laura O; Situmorang, Nasib M
Jurnal Kedokteran Methodist Vol. 17 No. 2 (2024): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v16i1.1673

Abstract

Background: of the study. Damage to the structure and function of the brain can lead to a decline and impaired cognitive function. This cognitive impairment can be caused by increasing age and risk factors such as dyslipidemia, hypertension, diabetes and cerebral blood vessels. Methods: This study used a cross-sectional design. The research population is all the elderly who are in the working area of the Simalingkar Health Center in 2022 as many as 500 people. The sample size is 66 people. The sampling technique was carried out using a consecutive sampling technique. Hypercholesterolemia data collection is based on medical record data, while cognitive impairment uses a mini mental status examination questionnaire. Analysis of research data using univariate and bivariate with Chi Square test. Results: showed that the majority of the elderly experienced hypercholesterolemia as many as 50 people (76.9%), and cognitive function in the elderly mostly in the normal category as many as 41 people (56.9%). There was no correlation between hypercholesterolemia and cognitive function in the elderly (p = 0.231 > 0.05). Conclusion: Hypercholesterolemia is not associated with cognitive function in the elderly.
A ASSOCIATION OF BODY MASS INDEX WITH HEALTH RELATED QUALITY OF LIFE IN ELEMENTERY SCHOOL AGE CHILDREN Japanto, Edwin Timoti
Jurnal Kedokteran Methodist Vol. 18 No. 1 (2025): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v20i1.1863

Abstract

Background : Nutrition problems in school-age children still occur in Indonesia and associated with a decrease in quality of life in children. School-age children are vulnerable to physical, emotional, social and school problems. Objective : To find out the relation between Body Mass Index (BMI) with Health Related Quality of Life (HRQOL) Methods : This cross-sectional study measured BMI with body weight and height using the z-score method and measuring quality of life (QOL) in children using a generic core scale Pediatric Quality of Life Inventory (PedsQL) 4.0. This research was conducted on school-age children 8-12 years old at Budya Wacana Yogyakarta Elementary school in 2018. Results: The statistical test on 143 respondents using chi square test for bivariate and logistic regression for multivariate. The bivariate test results showed a significant relationship between BMI and quality of life in children (p = 0.013), especially in the domain of emotional function (p = 0.015) and social function (p = 0.036). There was a significant relationship between age and quality of life (p = 0.002) and between sex with quality of life (p = 0.037). There was no significant relationship between disease and quality of life (p = 0.975). The results of multivariate analysis showed BMI (p = 0.001) had a greater correlation between quality of life in children than age (p = 0.03) or sex (p = 0.076). Conclusion : There is a significant relationship between BMI and quality of life in school-aged children at SD Budya Wacana Yogyakarta
CHF ec STENOSIS AORTA ec RHD + PH SEKUNDER Manullang, Doharjo; Tarigan, Menang Bastanta; Simanjuntak, Salomo G U; Situmeang, Ivonne; Simanjuntak, Evi Rosa; Hutahaeng, Reinhard DJ
Jurnal Kedokteran Methodist Vol. 18 No. 1 (2025): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v20i1.4327

Abstract

Stenosis is the most common valvular heart disease in Europe and North America with fear of calcification in the elderly (2-7% of the population> 65 years) while congenital aortic stenosis is usually caused by rheumatic heart disease which is now rare and usually found in young age. Classification of Aortic Stenosis. Classification of Aortic Stenosis can be divided based on the severity divided into 3 parts of mild, moderate, severe and very severe. Echocardiography modality is one of the gold standard tools for determining Aortic Stenosis which in echocardiography can capture Peak aortic jet velocity, the mean pressure gradient aortic valve area. The following is a case report of a 36 year old man with CHF ec Aortic Stenosis ec Rheumatic Heart Disease. This case was only diagnosed about 1 month ago with complaints of shortness of breath and chest pain. And the patient immediately went to RSMH for further treatment. This case was appointed for the management and preparation for surgery as a definitive therapy so that it is expected to give the best results in this patient

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