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Indonesian Journal of Global Health Research
Published by Global Health Science Group
ISSN : 27149749     EISSN : 27151972     DOI : https://doi.org/10.37287/ijghr
Core Subject :
Indonesian Journal of Global Health Research is a open access, peer reviewed and refereed international journal. Indonesian Journal of Global Health Research aim to publish original research paper devoted to various area of all health sciences. Indonesian Journal of Global Health Research provides a forum for sharing timely and up-to-date publication of scientific research, health care and promoting the development of nursing, public health, community, environmental and occupational health. The journal publishes original research papers of health sciences. High priority will be given to articles on public, nursing, adolescent, community, environmental and occupational health, pharmaceutical technology, social pharmacy, traditional medicine, pharmacology, and so on.
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Articles 868 Documents
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Relationship between Resilience Level and Mental Health in Female Victims of Sexual Harassment Bunga Annisa; Putri Nahrisah; Marthoenis Marthoenis; Dharina Baharuddin; Meutia Zahara
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2114

Abstract

Sexual harassment is a form of violence that has a serious impact on the mental health of victims, especially women, such as anxiety, depression, and Post Traumatic Stress Disorder (PTSD). This study aims to determine the relationship between resilience levels and mental health in female victims of sexual harassment in DDP3A Aceh in 2025. The method used is quantitative with a cross-sectional design. The population was 70 female victims who were in the DP3A Aceh Safe House, with a total sampling technique. The DASS-21 research instrument has demonstrated satisfactory validity and reliability, with Cronbach's alpha coefficients ranging from 0.88–0.94 for the depression subscale, 0.82–0.87 for the anxiety subscale, and 0.90–0.91 for the stress subscale. The resilience scale also demonstrated acceptable reliability, with a Cronbach's alpha coefficient of 0.70. analyzed using logistic regression tests. The results of the bivariate analysis showed a significant relationship between age (p = 0.024), education (p = 0.007), residence (p = 0.001), the relationship between the victim and the perpetrator (p = 0.011), and resilience levels (p = 0.031) with the victim's mental health. However, the multivariate analysis showed no factors significantly related to depression. For the anxiety variable, living with family had a significant association (p=0.038; OR=0.19), while stress was significantly associated with the relationship between the perpetrator and victim (p=0.012; OR=0.14). It was concluded that bivariate analysis found several factors associated with mental health, but multivariate analysis found only certain factors to be significant.
Work Discipline of Staff Nurses: The Role of Workload and Related Factors Sondang Selviana; Tiarnida Nababan; Refi Ikhtiari
Indonesian Journal of Global Health Research Vol. 8 No. 4 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i4.2141

Abstract

This study aims to examine the work discipline of staff nurses: the role of workload and related factors at Royal Prima Hospital Jambi, including goals and abilities, leadership role modeling, compensation, disciplinary sanctions, and workload. The study employed a quantitative approach with a total of 55 staff nurse respondents. The results of the univariate analysis showed that most respondents had good work discipline (87.3%), good goals and abilities (87.3%), good leadership role modeling (87.3%), good compensation (81.8%), good disciplinary sanctions (89.1%), and moderate workload (61.8%). The bivariate analysis indicated significant relationships between goals and abilities, leadership role modeling, compensation, disciplinary sanctions, and workload with nurses’ work discipline (p < 0.05). Furthermore, multivariate analysis using logistic regression revealed that compensation was the most dominant factor associated with the work discipline of staff nurses (p = 0.003). The findings of this study conclude that improving the work discipline of staff nurses at Royal Prima Hospital Jambi is strongly influenced by compensation, in addition to leadership, competence, sanctions, and workload factors.
Association of Fruit and Vegetable Intake and Physical Activity with Primary Dysmenorrhea among Centrally Obese Adolescents Febi Febriana Kusnaidi; Vitri Widyaningsih; Intan Suraya Ellyas
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2161

Abstract

Primary dysmenorrhea is a common reproductive health issue among female adolescents and is closely linked to lifestyle factors, including dietary patterns and physical activity, particularly among those with central obesity. This study aims to analyze the relationship between fruit and vegetable consumption, exercise habits, and primary dysmenorrhea among adolescents with central obesity. An analytical observational study with a cross-sectional design was conducted in February 2026 across four public senior high schools in Surakarta. A sample of 128 centrally obese female students was selected using multistage sampling. Data were collected via interviews using a standardized FFQ, a validated 12-item exercise habits questionnaire (Pearson's r > 0.804; Cronbach's alpha = 0.970), and a standardized NRS. Data were analyzed using statistical software through univariate and bivariate analyses (p < 0.05). The majority of respondents reported irregular fruit and vegetable consumption (56.3%) and irregular exercise habits (55.5%), and most experienced moderate-to-severe dysmenorrhea. Statistically significant relationships were found between fruit and vegetable consumption and dysmenorrhea (p = 0.004) and between exercise habits and dysmenorrhea (p < 0.001). Irregular consumption and low physical activity were strongly associated with higher pain severity. Fruit and vegetable consumption and exercise habits are significantly associated with the severity of primary dysmenorrhea among adolescents with central obesity. Promoting healthy dietary habits and regular physical activity may mitigate the severity of dysmenorrhea in this population.
Modification Enteral Formula Based on Local Food as A Ketogenic Diet Formula for Epilepsy Patients Iis Sulastri; Erika Damayanti; Rosita Anwar
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2162

Abstract

Epilepsy is a neurological disorder that commonly occurs in children and can affect cognitive development, nutritional status, and quality of life. The ketogenic diet has been widely used as a nutritional therapy to help reduce seizure frequency in children with refractory epilepsy. This study evaluated the organoleptic characteristics, flow rate, and nutritional content of a local food-based ketogenic enteral formula for epilepsy patients using tempeh, cheddar cheese, and coconut oil. This study using a trial-and-error design. The ingredients are using tempeh, cheddar cheese, and coconut oil with three modification formulation tested on 35 panelists for organoleptic test, flow testing using an NGT tube, and proximate testing. Organoleptic testing showed that formulation F2 (57% tempeh and 37% cheese) had the highest acceptability in color, taste, and texture due to its balanced flavor, creamy mouthfeel, and homogeneous consistency. Flow rate testing using a 12-Fr enteral tube showed F1 had the lowest flow rate (2.2 cc/s), indicating higher viscosity, while F2 and F3 had better flow properties. Nutritional analysis of F2 showed a fat content of 8.40%, meeting ketogenic diet requirements. Coconut oil provided medium-chain triglycerides (MCTs) that support ketone production, while tempeh contributed moderate protein and potential gut health benefits. Overall, F2 was identified as the best formulation with good sensory acceptance, suitable viscosity, and appropriate nutritional composition for ketogenic enteral feeding in epilepsy patients. Modification of the ketogenic enteral diet formula for epilepsy patients resulted in the best formula, F2. F2 and F3 had better flow capacity than F1. Proximate analysis of F2 showed that its fat content met the ketogenic diet standard, which is 70% of total calories.
Analysis of Honey Cunsumption on Postpartum Mental Well-Being Siti Nurahayu; Retno Widowati; Vivi Silawati
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2164

Abstract

The postpartum period is a transitional period that is vulnerable to mental and physical health disorders. In Indonesia, the prevalence of emotional disorders in postpartum mothers reaches 18–28%, severe fatigue is around 30–40% in the first week postpartum, and postpartum anemia ranges from 22–50%. Honey contains simple carbohydrates, vitamins, minerals, and antioxidants that have the potential to support physical recovery and psychological stability in mothers. To analyse the honey consumption on mental well-being and physical of postpartum mother in South Tangerang City and to compare the difference between intervention and control groups. This was a quasi experimental study, pretest, and posttest design. There were 60 postpartum mother and assigned into two groups, namely intervention group (n=30) and control group (n=30). Intervention group received honey twice a day during 21 days. Data analysis was conducted using univariate analysis to describe variables and bivariate analysis to test the effect using parametric or non-parametric statistical tests based on the Kolmogorov-Smirnov normality test, with a significance level of p < 0.05. The HARS, DASS 21, FAS, and Hb were used. The validity and reliability testing was based on prior research, utilizing a Cronbach's alpha coefficient of 0,89. The results showed a significant difference between pre-test and post-test scores on anxiety (p=0.001), stress (p=0.002), fatigue (p=0.001), and hemoglobin levels (p=0.000). There was a significant difference between intervention and control groups (p<0.05). Honey consumption can decrease anxiety, stress, fatigue, and increase Hb levels among postpartum mother.
Iron Chelation, Vitamins, and Supplements for Thalassemia Patients: Scoping Review Dewi Rejeki; Priyanto Priyanto; Feriana Ira Handian
Indonesian Journal of Global Health Research Vol. 8 No. 4 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i4.2179

Abstract

Thalassemia major and transfusion-dependent thalassemia (TDT) are hereditary hemoglobinopathies that require lifelong blood transfusions and iron chelation therapy to prevent complications related to iron overload. Despite advances in chelation therapy, patients continue to experience complications such as oxidative stress, endocrine disorders, and bone health deterioration. This scoping review aimed to synthesize evidence from research articles regarding the role of iron chelation agents, including deferoxamine (DFO), deferiprone (DFP), and deferasirox (DFX), together with vitamin and supplement interventions in the management of thalassemia patients. This study used the PRISMA-ScR guidelines to identify scientific articles published between 2016 and 2025 from the PubMed and Scopus databases. Eligible studies were selected through title, abstract, and full-text screening according to predefined inclusion and exclusion criteria. Data were extracted, categorized by intervention type, and synthesized descriptively to examine the role of iron chelation therapy, vitamin C, vitamin D, vitamin E, folic acid, calcium, and antioxidant supplements in thalassemia management. A total of 29 articles met the inclusion criteria and were reviewed.  The main findings demonstrated that vitamin C enhances the effectiveness of iron chelation therapy, particularly when combined with DFO. Vitamin D and calcium supplementation improve bone mineral density and reduce the risk of osteoporosis. Vitamin E and other antioxidants help reduce oxidative stress, while appropriate folic acid supplementation prevents deficiency without causing excessive accumulation. The combination of iron chelation therapy with vitamins and supplements provides benefits in reducing complications associated with iron overload, improving bone health, and decreasing oxidative stress in patients with thalassemia. This review offers evidence-based insights to optimize nutritional management in patients with thalassemia undergoing iron chelation therapy.
Efficacy and Safety of Oral Jak Inhibitor as Current Therapy of Vitiligo: A Systematic Review Edison Febrianto; Made Hemina Laksmi; Anak Agung Ari Agung Kayika Silayukti; Tjokorda Istri Amrita Rosvanti; Anak Agung Istri Saraswati Dewi
Indonesian Journal of Global Health Research Vol. 8 No. 4 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i4.2181

Abstract

Vitiligo is an autoimmune depigmenting disorder driven by IFN-γ–mediated, CD8+ T cell cytotoxicity against melanocytes via JAK-STAT signaling. While topical ruxolitinib (JAK1/2) is FDA-approved, the efficacy and safety of oral JAK inhibitors for vitiligo remain under investigation. This systematic review evaluates current evidence for oral JAK inhibitors (upadacitinib, abrocitinib, tofacitinib) in vitiligo, including their use with adjunctive therapies. Following a PRISMA-ScR approach, PubMed was searched (2019–2026) using MeSH terms (“JAK Inhibitor” AND “Vitiligo”). Eligible designs included case reports, case series, and randomized controlled trials. Studies are organized into table with each selected data. The data extracted are explained. Evidence consists predominantly of case reports/series and one randomized trial. Oral JAK1-selective agents (upadacitinib, abrocitinib) and JAK1/3 inhibitor tofacitinib frequently produced meaningful repigmentation, especially on facial sites, with response often enhanced by light-based adjuncts (NB-UVB or 308-nm excimer). Reported examples include ~60–90% facial repigmentation with upadacitinib or abrocitinib when combined with excimer or in patients with concomitant atopic dermatitis, and near-complete facial repigmentation with tofacitinib, particularly in sun-exposed areas or when paired with NB-UVB. Abrocitinib’s higher JAK1 selectivity may preserve JAK2-mediated melanocyte survival signals, potentially explaining benefit in a case where vitiligo worsened on upadacitinib but improved after switching to abrocitinib. Safety across studies was generally acceptable, with mostly mild adverse events (e.g., acne, upper respiratory infections, fatigue, nasopharyngitis, weight gain, lipid elevations). Laboratory abnormalities were typically minimal. Oral JAK inhibitors show promising efficacy for vitiligo, particularly for facial lesions and when combined with phototherapy, with an overall favorable short- to mid-term safety profile. Adjunctive light therapy likely augments outcomes and may permit lower systemic doses.
The The Association of NLR and PLR with Hard Callus Formation in Single Closed Long Bone Fractures Miranda Putri Rahayu; Malayana Rahmita Nasution; Aga Shahri Putera Ketaren
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2182

Abstract

Closed long bone fractures require a complex healing process involving inflammation and callus formation. The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have been proposed as potential biomarkers in the fracture healing process. To analyze the correlation between NLR, PLR, and hard callus formation in patients with a single closed long bone fracture. This retrospective cohort study involved 42 patients treated at RSUP H. Adam Malik Medan from January 2023 to December 2025. Patients were divided into a hard callus group (n=27) and a non-hard callus group (n=15) based on six-month radiological evaluation. Baseline neutrophil, lymphocyte, and platelet counts, NLR, PLR, and radiological findings were collected from medical records. Radiological findings were assessed by comparing the initial radiographs with those obtained at the six-month follow-up to evaluate callus formation. No significant differences in hematological parameters were found between the two groups (p > 0.05). Neither NLR (p = 0.694) nor PLR (p = 0.581) showed a significant association with hard callus formation. Logistic regression and ROC analysis also demonstrated low predictive ability for both NLR (AUC 0.537) and PLR (AUC 0.448). NLR and PLR are not associated with hard callus formation and have limited predictive value for bone healing in closed long bone fractures.
Effect of A Pulmonary Rehabilitation Program on Dyspnea Severity Assessed by the Modified Medical Research Council Scale in Patients with Stable Chronic Obstructive Pulmonary Disease Nana Naharja Harahap; Amira Permatasari Tarigan; Pandiaman Pandia
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2186

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is a progressive lung disease characterized by persistent airflow limitation and chronic respiratory symptoms, particularly dyspnea, which negatively impacts functional capacity and quality of life. Pulmonary rehabilitation is an essential component of COPD management; however, its effectiveness in reducing dyspnea in stable COPD patients at the local healthcare level still requires further evaluation. To determine the effect of a pulmonary rehabilitation program on dyspnea severity assessed by  Modified Medical Research Council Scale (mMRC). This study employed a quasi-experimental one-group pretest–posttest design to evaluate the effect of a pulmonary rehabilitation program on dyspnea severity, as measured by the mMRC scale, among 28 male subjects with stable COPD recruited through consecutive sampling. Dyspnea severity was assessed using the mMRC scale before and after a 4-week pulmonary rehabilitation program. Demographic and clinical data were collected at baseline. Statistical analyses were performed using the Shapiro–Wilk test and paired t-test or Wilcoxon signed-rank test, with p < 0.05 considered statistically significant. Most patients were elderly, predominantly aged 60–69 years. Before the intervention, the majority experienced moderate to severe dyspnea. After pulmonary rehabilitation, there was a shift toward lower mMRC scores, indicating clinical improvement. Statistical analysis showed a significant difference between pre- and post-intervention scores (Z = −3.771; p < 0.001) with a very large effect size (r = 0.97), indicating a strong impact of pulmonary rehabilitation on reducing dyspnea in stable COPD patients. Pulmonary rehabilitation is effective in reducing dyspnea severity and improving functional condition in patients with stable COPD.
Fast Food, Fiber Intake, Sleep Duration, and Physical Activity as Predictors of Excess Weight in Surakarta Adolescents Pujiyati Pujiyati; Kusnandar Kusnandar; Anik Lestari
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2224

Abstract

Overweight among adolescents results from an energy imbalance between caloric intake and energy expenditure. The World Health Organization (WHO) has declared obesity a global epidemic, with approximately 28.5% of Indonesian adolescents reported to have excess body mass index (BMI). This study aimed to analyze the association between fast food consumption frequency, dietary fiber intake, sleep duration, and physical activity with the severity of excess weight status (overweight vs. obesity) among adolescents aged 16–18 years in Surakarta, Indonesia. This cross-sectional study involved 100 respondents with excess weight. Data were collected using a Food Frequency Questionnaire (FFQ), Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ), Sleep Duration Questionnaire (STQ), and International Physical Activity Questionnaire (IPAQ), with nutritional status determined through anthropometric measurements. The FFQ and SQ-FFQ had been previously validated with a Pearson correlation coefficient r > 0.6 and reliability coefficient (Cronbach's alpha) > 0.7. The STQ was validated with r > 0.6 and Cronbach's alpha > 0.8, while the IPAQ has been internationally validated and widely used across studies. Nutritional status was determined through anthropometric measurements.  Data analysis included chi-square tests and binary logistic regression. Of 100 respondents, 56% were classified as overweight and 44% as obese. Chi-square analysis revealed significant associations between fast food consumption frequency (p = 0.020), dietary fiber intake (p < 0.001), and sleep duration (p = 0.013) with the severity of excess weight status, while physical activity showed no significant association (p = 0.912). Binary logistic regression identified low dietary fiber intake as the most dominant risk factor (OR = 29.034; 95% CI = 6.216–135.605; p < 0.001), followed by low fast food consumption frequency (OR = 7.941; 95% CI = 1.447–43.579; p = 0.017). Low dietary fiber intake is the most dominant risk factor for the severity of excess weight status among adolescents.   

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