cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
mkb.fkunpad@gmail.com
Editorial Address
Gedung Rumah Sakit Pendidikan Unpad/Pamitran Unpad (Teaching Hospital Building) Faculty of Medicine Unpad, 3rd Floor Jl. Prof. Eyckman No. 38 Bandung, 40161, Indonesia
Location
Kota bandung,
Jawa barat
INDONESIA
Majalah Kedokteran Bandung
Published by Universitas Padjadjaran
ISSN : 0126074X     EISSN : 23386223     DOI : 10.15395/mkb
Core Subject : Health,
Medicine & Pharmacology
Majalah Kedokteran Bandung (MKB)/Bandung Medical Journal publishes peer-reviewed original articles and case reports in basic medical research, clinical research, and applied medical science. This journal is published quarterly (March, June, September, and December) by Faculty of Medicine Universitas Padjadjaran. Articles are original research that needs to be disseminated and written in English. All submitted manuscripts will go through the double-blind peer review and editorial review before being granted with acceptance for publication.
Arjuna Subject : -
Articles 639 Documents
 12   13   14   15   16 
PERBEDAAN EFEK TERAPI PENGGUNAAN DUA UKURAN JARUM DRY NEEDLING DENGAN PENURUNAN NYERI DAN TENDERNESS PADA SINDROM NYERI MIOFASIAL OTOT UPPER TRAPEZIUS TIPE AKTIF Taofik, Nora; Prabowo, Tertianto; Sastradimaja, Sunaryo. B.
Majalah Kedokteran Bandung Vol 47, No 2 (2015)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (166.394 KB)

Abstract

Sindrom nyeri miofasial adalah kumpulan gejala sensorik, motorik, dan autonom akibat miofasial trigger point. Sindrom ini paling sering didapatkan pada usia muda dan mengenai otot postural, salah satunya adalah otot upper trapezius. Terapi yang digunakan berupa terapi invasif maupun noninvasif. Terapi invasif dengan ukuran jarum yang berbeda dapat memberikan penurunan gejala dalam beberapa saat setelah terapi. Uji klinis dilakukan dengan metode pengambilan sampel consecutive sampling. Penelitian dilakukan di Departemen Kedokteran Fisik dan Rehabilitasi Medik Rumah Sakit Dr. Hasan Sadikin Bandung periode April?Mei 2104. Subjek penelitian kelompok I diberikan terapi dry needling menggunakan jarum injeksi 25G (0,50x25 mm) dan kelompok II diberikan terapi dry needling menggunakan jarum akupuntur 1 cun (0,25x25 mm). Subjek penelitian sebanyak 74 orang dibagi menjadi 2 kelompok. Perbandingan nilai numeric rating scale antara terapi dengan jarum injeksi 25G dan jarum akupunktur 1 cun tidak didapatkan perbedaan bermakna (p=0,230). Perbandingan nilai algometer antara terapi dengan jarum injeksi 25G dan jarum akupunktur 1 cun tidak didapatkan perbedaan bermakna (p=0,134). Tidak ada perbedaan efek terapi dry needling terhadap penurunan nyeri dan tenderness pada penderita sindrom nyeri miofasial otot upper trapezius tipe aktif antara menggunakan jarum injeksi 25G dan jarum akupunktur 1 cun. [MKB. 2015;47(2):91?5]Kata kunci: Dry needling, jarum akupunktur, jarum injeksi, upper trapezius, sindrom nyeri miofasialEffect of Treatment Differences between the Use of Two Different Sizes of Dry Needling to Decrease Pain and Tenderness in Active Upper Trapezius Myofascial Pain SyndromeAbstractMyofascial pain syndrome is a collection of sensoric, motoric, and autonomic symptoms due to myofascial trigger points. This is commonly seen in young age and involves postural muscles; one of those is upper trapezius muscle. Invasive and non-invasive therapies have been used as modalities to treat myofascial pain syndrom. Invasive therapy is superior due to its mechanical mechanism in deactivating trigger points. Different sizes of needles are used in invasive therapy to decrease symptoms.  A clinical trial has been conducted in the outpatient clinic of Department of Physical Medicine and Rehabilitation, Dr. Hasan Sadikin Hospital, Bandung in the period of April?May 2014 with consecutive sampling method. Subjects in group I were given dry needling therapy with 25G injection needle (0.50x25 mm) and subjects in group II received the therapy using 1 cun accupuncture needle (0.25x25 mm). Seventy four subjects participated in this study. The comparison of numeric rating scale between the 25G injection needle therapy group and the 1 cun accupuncture needle therapy group was not significantly different (p=0.230). The comparison of algometer value between the 25G injection needle therapy group and the 1 cun accupuncture needle therapy group was also not significantly different (p=0.134). In conclusion, there is no difference in pain and tenderness decrease in dry needling therapy using 25G injection needle and 1 cun accupuncture needle for active type of myofascial pain syndrome of upper trapezius muscle therapies. [MKB. 2015;47(2):91?5]Key words: Acupuncture needle, dry needling, myofascial pain syndrome, needle, upper trapezius DOI: 10.15395/mkb.v47n2.462
KESESUAIAN TERHADAP PROSEDUR STANDAR RESUSCITATION BUNDLE 6 JAM PADA PELAKSANAAN PENDERITA SEPSIS BERAT DAN SYOK SEPSIS Wirawan, Chevie; Alisjahbana, Bachti; Sumardi, Uun
Majalah Kedokteran Bandung Vol 50, No 1 (2018)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (15.169 KB) | DOI: 10.15395/mkb.v50n1.1157

Abstract

Sepsis berat dan syok sepsis memiliki angka kematian tinggi. Resuscitation bundle 6 jam adalah panduan tata laksana sepsis berat dan syok sepsis yang terbukti menurunkan mortalitas. Kesesuaian penatalaksanaan sepsis berat dan syok sepsis dalam 6 jam pertama dengan prosedur standar resuscitation bundle diteliti. Penelitian observasional deskriptif ini dilaksanakan selama September?Desember 2015 terhadap penderita sepsis berat dan syok sepsis di SMF Ilmu Penyakit Dalam RSUP Dr. Hasan Sadikin Bandung. Data dikumpulkan adalah data umum penderita dan pelaksanaan prosedur 6 jam pertama sesuai standar: pemeriksaan laktat, kultur darah, pemberian antibiotik, resusitasi cairan, pemberian vasopresor, pengukuran CVP, dan pemeriksaan Scvo2/Svo2. Dari 80 subjek penelitian, 59 (74%) sepsis berat dan 21 (26%) syok sepsis. Pada sepsis berat dan syok sepsis, dalam 3 jam pertama pemeriksaan laktat dilakukan pada 2%  dan 14%, kultur darah sebelum antibiotik 17% dan 10%, pemberian antibiotik spektrum luas 32% dan 43%, serta  resusitasi cairan 30 mL/kgBB 2% dan 14%. Pada syok sepsis dalam 6 jam pertama pemberian vasopresor 62% dan pengukuran CVP 5%. Pemeriksaan Scvo2/Svo2 tidak dilakukan pada syok sepsis. Angka kematian sepsis berat 7% dan syok sepsis 19,1% dalam 6 jam pertama. Simpulan, kesesuaian penatalaksanaan 6 jam pertama penderita sepsis berat dan syok sepsis dengan prosedur standar masih kurang.Kata kunci: Resuscitation bundle 6 jam, sepsis berat, syok sepsis  Compliance to 6-Hour Resuscitation Bundle Standard in Severe Sepsis and Septic Shock ManagementSevere sepsis and septic shock have a high mortality rate. Six-hour resuscitation bundle is a management standard for severe sepsis and septic shock that has been proven to reduce mortality rate. Compliance to the 6-hour resuscitation bundle standard was studied. This was a descriptive observational study on severe sepsis and septic shock patients in the Internal Medicine Department of Hasan Sadikin General Hospital Bandung in the period of September?December 2015. Data collected were patient?s general data and the implementation of the 6-hour management standard procedures that include lactate measurement, blood culture, broad spectrum antibiotics, fluid resuscitation, vasopressor use, CVP measurement, and Scvo2/Svo2 measurement. Of 80 subjects, 59 (74%) had severe sepsis and 21 (26%) had septic shock. In the first 3 hours, for severe sepsis and septic shock patients, lactate was examined in 2% and 14% respectively. For blood culture before antibiotics, broad spectrum antibiotic provision, and 30 mL/kgWt fluid resuscitation, the values were 17% and 10%, 32% and 43%; and 2% and 14%, respectively. In septic shock, in the 6 hours, vasopressor was given to 62% and CVP was measured in CVP 5%. Scvo2/Svo2 was not measured. The mortality rates in the first 6 hours for severe sepsis and septic shock were 7% and 19%. Compliance to first 6-hour standard procedure for severe sepsis and septic shock is still inadequate. Key words: Septic shock, severe sepsis, six hours resuscitation bundle
Functional Independence Measure Penderita Cedera Servikal Arifin, Muhammad Zafrullah; Henky, Jefri
Majalah Kedokteran Bandung Vol 45, No 3 (2013)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (802.757 KB)

Abstract

Cedera servikal merupakan salah satu cedera tulang belakang terbanyak pada penderita trauma. Di Amerika Serikat tahun 2008 dari 100.000 kasus cedera tulang belakang, 2/3 merupakan kasus cedera servikal. Penilaian awal dilakukan berdasarkan American Spinal Cord Injury Association (ASIA) Impairment Score, sedangkan hasil setelah penatalaksanaannya sering diabaikan untuk evaluasi keberhasilan ahli di rumah sakit. Tujuan penelitian untuk mengetahui nilai functional independence measure (FIM) penderita cedera servikal dengan manajemen konservatif dan korelasinya dengan usia, jenis kelamin, jenis trauma, onset trauma, abnormalitas tulang servikal, lesi cervical spine, dan ASIA Impairment Score. Dilakukan studi kohor prospektif pada semua pasien cedera servikal yang memenuhi kriteria inklusi di Departemen Bedah Saraf Rumah Sakit (RS) Dr. Hasan Sadikin Bandung. Subjek dikelompokkan berdasarkan usia, jenis kelamin, trauma tunggal/multipel, akut/kronik, abnormalitas tulang servikal, lesi komplet/inkomplet, ASIA Impairment Score, dan komplikasi awal cedera. Pada penderita dilakukan penilaian FIM di Poliklinik Bedah Saraf. Data dianalisis menggunakan uji-t dan uji chi-kuadrat dengan p<0,05. Terdapat 17 penderita cedera servikal yang dirawat di Departemen Bedah Saraf RS Dr. Hasan Sadikin Bandung periode April 2009–April 2010. Observasi kohor prospektif nilai FIM rata-rata penderita cedera servikal adalah 4+1,63. Analisis chi-kuadrat menyatakan bahwa tidak terdapat hubungan usia (p=0,064), jenis kelamin (p=0,144), jenis trauma penyerta (p=0,959), onset cedera (p=0,220), abnormalitas tulang servikal (p=0,869) dengan besarnya nilai FIM pasien cedera servikal. Terdapat hubungan jenis lesi cervical spine (p=0,037), ASIA Impairment Score (p<0,001) dengan besarnya nilai FIM penderita cedera servikal. Simpulan, jenis lesi cervical spine dan ASIA Impairment Score memiliki hubungan bermakna dengan besarnya nilai FIM penderita 3 bulan pascacedera servikal. [MKB. 2013;45(3):180–6]Functional Independence Measure in Patients with Cervical Spine InjuryCervical spine injury is one of the most common spinal cord injuries in trauma patients. From 100,000 spinal cord injury cases reported in the United States of America (2008), 2/3 involved cervical spine injury. American Spinal Cord Injury Association (ASIA) Impairment Score is used as an initial assessment but further prognostic outcome of these patients is often not paid enough attention. The objective of this study was to find the value of functional independence measure (FIM) cervical spine injury patients with conservative management and correlation with age, sex, type of trauma, onset of trauma, cervical bone abnormalities, type of spinal lesion and ASIA Impairment Score. A prospective cohort study was performed to all patients with cervical spine injury which fullfil the inclusion criteria treated in Neurosurgery Department of Dr. Hasan Sadikin Hospital Bandung. The subjects were classified based on age, sex, single/multiple trauma, acute/chronic, cervical bone abnormalities, complete/incomplete lesion, ASIA impairment score and initial complication. The patients were performed to FIM examination in Outpatient clinic of Neurosurgery. T-test and chi-square test with p<0.05 were done to analyze the data. There were 17 cervical spine injury patients treated in Neurosurgery Department of Dr. Hasan Sadikin Hospital Bandung during April 2009–April 2010. The average FIM value of cervical spine injury in those patients was 4+1.63 by cohort prospective study. There were no correlation between FIM value with age (p=0.064), sex (p=0.144), type of trauma (p=0.959), onset of trauma (p=0.220) and cervical bone abnormalities (p=0.869). We found a significant correlation between FIM value with type of cervical spine lesion (p=0.037) and ASIA Impairment Score (p<0.001) in cervical spine patients. In conclusion, type of cervical spine lesion and ASIA impairment score have significant correlation with FIM value of patients in 3 months after cervical injury.[MKB. 2013;45(3):180–6] DOI: http://dx.doi.org/10.15395/mkb.v45n3.15
HUBUNGAN KADAR LEPTIN SERUM DENGAN KOMPLEKSITAS LESI KORONER BERDASARKAN SKOR SYNTAX PADA PENDERITA PENYAKIT ARTERI KORONER STABIL Ashari, Fajar; Aprami, Toni Mustahsani; Akbar, Muhammad Rizki; Purnomowati, Augustine; Martha, Januar Wibawa; Achmad, Chaerul; Martanto, Erwan
Majalah Kedokteran Bandung Vol 48, No 1 (2016)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (165.975 KB) | DOI: 10.15395/mkb.v48n1.730

Abstract

Leptin memiliki peran penting dalam pembentukan plak ateroskleosis dengan mengaktifkan respons sel imun dan respons inflamasi ataupun peran langsung terhadap dinding pembuluh darah koroner. Penelitian terdahulu mengenai hubungan antara kadar leptin serum dan kompleksitas lesi koroner masih menunjukkan kontroversi. Penelitian ini bertujuan mengetahui hubungan antara kadar leptin serum dan kompleksitas lesi koroner berdasarkan skor SYNTAX pada penderita penyakit arteri koroner stabil. Metode penelitian berupa observasional, deskriptif, dan analisis korelasi dengan rancangan potong lintang. Subjek penelitian sebanyak 44 orang penderita penyakit arteri koroner (PAK) stabil yang memenuhi kriteria inklusi, menjalani pemeriksaan angiografi koroner di Rumah Sakit Dr. Hasan Sadikin Bandung selama bulan Januari?Mei 2014. Pengambilan sampel darah untuk pemeriksaan kadar leptin serum dilakukan sebelum tindakan angiografi. Kompleksitas lesi arteri koroner dinilai menggunakan skor SYNTAX. Hasil penelitian didapatkan subjek penelitian 84% laki-laki dengan usia rata-rata 54,68 (+10,24) tahun. Indeks massa tubuh rata-rata 24,71 (+ 3,05) kg/m2. Faktor risiko terbanyak adalah dislipidemia (84%), merokok (72%), hipertensi (38,4%), diabetes melitus (22,7%), dan obesitas (4,5%). Median kadar leptin serum 7.242 (780?36.929) pq/mL, nilai rata-rata skor SYNTAX sebesar 19,52 (+9,93). Analisis menggunakan uji korelasi rank-Spearman tidak didapatkan hubungan (p=0,61; r= 0,078). Perbedaan hasil penelitian ini dengan penelitian sebelumnya disebabkan oleh perbedaan subjek dan kriteria penilaian kompleksitas lesi arteri koroner. Simpulan, tidak terdapat hubungan antara kadar leptin serum dan kompleksitas lesi koroner berdasarkan skor SYNTAX pada penderita penyakit arteri koroner stabil. [MKB. 2016;48(1):26?31]Kata kunci: Kompleksitas lesi koroner, leptin serum, penyakit arteri koroner stabil, skor SYNTAXCorrelation between Serum Leptin Levels and Complexity of Coronary Artery Lesion based on SYNTAX Score in Patients with Stable Coronary Artery DiseaseAbstractLeptin has been shown to play a potential role in the atherosclerotic plaque formation by activating immune and inflammatory cells or directly acting on the vessel wall. Earlier reports of the correlation of serum leptin levels with the degree of coronary lesion stated are still controversial. This study determined the correlation between serum leptin levels and complexity of coronary artery lesion in patients with stable coronary artery disease (SCAD). This is an observational cross-sectional study. Data were collected from January to May 2014 in Dr. Hasan Sadikin Central General Hospital Bandung. Blood samples were collected before angiography procedures. The complexity of coronary artery lesion was assessed using SYNTAX score. There were 44 patients who met inclusion criteria, male 84%, median age 54.68 (+10.24) years. Mean body mass index 24.71 (+ 3.05) kg/m2. Dyslipidemia was the most common risk factor (84%), followed by smoking (72%), hypertension (38.4%), diabetes mellitus (22.7%), and obesity (4.5%). Median leptin level was 7,242 (780-36,929) pq/mL. Mean SYNTAX score was 19.52 (+9.93). Leptin level had no correlation with the complexity of coronary artery lesion (p=0.61, r=0.078). The difference between this study from prior studies might be caused by differences in subject selection and criteria used for complexity of coronary artery lesion. In conclusion, there is no correlation between serum leptin levels and complexity of coronary artery lesion in patients with stable coronary artery disease. [MKB. 2016;48(1):26?31]Key words: Complexity of coronary artery lesion, leptin, stable coronary artery disease, SYNTAX score
TNF-α-ACTIVATED MSC-CM TOPICAL GEL EFFECTIVE IN INCREASING PDGF LEVEL, FIBROBLAST DENSITY, AND WOUND HEALING PROCESS COMPARED TO SUBCUTANEOUS INJECTION COMBINATION Kuntardjo, Novalia; Dharmana, Edi; Chodidjah, Chodidjah; Nasihun, Taufiq R; Putra, Agung
Majalah Kedokteran Bandung Vol 51, No 1 (2019)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v51n1.1479

Abstract

Mesenchymal stem cells (MSCs) are multipotent stromal cells that have the capacity to regenerate tissue damage. However, they have several limitations. MSC-CM as a new approach treatment is widely used to solve the limitation of MSC in wound healing. The aim of this study was to evaluate the effectiveness of TNF-?-activated MSC-CM topical gel compare to topical-subcutaneous injection combination on wound healing acceleration. This study was conducted between April and August 2018 at the Stem Cell and Cancer Research Laboratory (SCCR), Faculty of Medicine, Sultan Agung Islamic University, Semarang. Experimental post-test only control group design was performed by involving 36 animal models randomly divided into six groups; T1, T2 (MSC-CM in topical gel 100 ?L; 200 ?L); ST1, ST2 (MSC-CM in subcutaneous injection : topical gel = 80 ?L:20 ?L; 160 ?L:40 ?L); CT (200 ?L medium free TNF-?); CST (PBS in subcutaneous injection : topical gel = 160 ?L :40 ?L). The measurement of PDGF level on day 3 and 6 was conducted using ELISA assay while the fibroblast density was analyzed by light microcopy. It was found that there was was a significant increase in PDGF and fibroblast density on day 6 in the topical group when compared to the combination group (p<0,05). It is concluded that the MSC-CM topical gel is more effective than combination of topical-subcutaneous injection.Key words: Combination, fibroblast, MSC-CM, PDGF, subcutaneous MSC-CM, topical MSC-CM MSC-CM Topikal yang diaktivasi TNF-? Efektif Dalam Peningkatan Level PDGF, Densitas Fibroblast, dan Mempercepat Penyembuhan Luka dibanding dengan Kombinasi Injeksi SubkutanMesenchymal stem cells (MSCs) merupakan sel stroma multipoten yang memiliki kemampuan untuk meregenerasi kerusakan jaringan. Namun, MSC memiliki beberapa keterbatasan. MSC-CM sebagai terapi pendekatan baru digunakan untuk mengatasi keterbatasan MSC dalam penyembuhan luka. Tujuan penelitian ini adalah menilai efektivitas MSC-CM topikal yang diaktvasi TNF-? dibandingdengan kombinasi topikal-injeksi subkutan pada percepatan penyembuhan luka. Penelitian ini dilaksanakan pada bulan April?Agustus 2018 di Laboratorium Stem Cell and Cancer Research (SCCR), Fakultas Kedokteran, Universitas Islam Sultan Agung, Semarang. Penelitian menggunakan eksperimen laboratorium dengan rancangan post-test only control group, menggunakan 36 tikus galur wistar yang dibagi secara acak menjadi 6 kelompok; T1, T2 (MSC-CM gel topikal 100?L; 200?L); ST1, ST2 (MSC-CM injeksi subkutan : gel topikal = 80 ?L:20 ?L; 160 ?L:40 ?L); CT (200 ?L medium tanpa TNF-?); CST (PBS injeksi subkutan: gel topikal = 160 ?L :40 ?L). Pengukuran kadar PDGF pada hari ke-3 dan ke-6 mengunakan ELISA, sedangkan jumlah fibroblas dilihat mengunakan mikroskop cahaya. Hasil penelitian ini menunjukkan peningkatan kadar PDGF dan jumlah fibroblas yang signifikan dihari ke-6 pada MSC-CM gel topikal dibanding dengan kombinasi topical-injeksi subukutan (p <0.05). Simpulan penelitian ini adalah pemberian MSC-CM secara topical lebih efektif dibanding dengan kombinasi topikal-injeksi subkutan.Kata kunci: Fibroblas, konditional medium, MSC-CM kombinasi, MSC-CM topikal, PDGF
Hubungan antara QT Variability Index dan Laju Filtrasi Glomerulus pada Penyakit Ginjal Kronik Predialisis Sugiantoro, -; Purnomowati, Augustine; Martakusumah, Abdul Hadi; Achmad, Chaerul
Majalah Kedokteran Bandung Vol 44, No 4 (2012)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (708.08 KB)

Abstract

Penderita penyakit ginjal kronik (PGK) mempunyai risiko yang tinggi untuk mengalami aritmia ventrikel dan kematian mendadak (sudden cardiac death/SCD). Angka kejadian SCD pada penderita PGK meningkat seiring dengan menurunnya laju filtrasi glomerulus (glomerular filtration rate/GFR). Mekanisme patofisiologi yang mendasari SCD pada umumnya aritmia ventrikel yang berhubungan dengan ketidakstabilan repolarisasi miokardium. QT variability index (QTVI), suatu indeks yang menggambarkan ketidakstabilan repolarisasi miokardium, merupakan prediktor yang kuat untuk terjadi aritmia fatal dan SCD. Penelitian ini merupakan studi observasi potong lintang untuk menilai hubungan antara QTVI dan GFR pada penderita PGK predialisis dengan GFR <60 mL/menit. Penelitian ini dilakukan pada penderita PGK yang berobat ke Poliklinik Ginjal Hipertensi Rumah Sakit Dr. Hasan Sadikin Bandung periode Oktober–Desember 2011. Penelitian ini melibatkan 51 subjek. Pemeriksaan elektrokardiografi (EKG) istirahat dilakukan pada semua subjek dan selanjutnya dilakukan penghitungan QTVI. Hampir semua subjek menderita hipertensi atau mendapat antihipertensi (94%). Gambaran EKG dengan hipertrofi ventrikel kiri didapatkan pada 37% subjek dan QTVI rata-rata subjek sebesar 0,16 (SD 0,24). Hubungan antara QTVI dan GFR dianalisis menggunakan Spearman’s rank correlation. QT variability index mempunyai hubungan yang bermakna baik dengan GFR (r=-0,816; p<0,001) maupun dengan estimated glomerular filtration rate (eGFR) (r=-0,460; p<0,001). Simpulan, terdapat hubungan sangat kuat antara QTVI dan GFR pada penderita PGK predialisis, makin rendah GFR makin panjang nilai QTVI. [MKB. 2012;44(4):193–98].Kata kunci: Kematian jantung mendadak, laju filtrasi glomerulus, penyakit ginjal kronik, QT variability indexCorrelation between QT Variability Index and Glomerular Filtration Rate in Predialysis Chronic Kidney DiseaseAbstractChronic kidney disease (CKD) patients are at increased risk for ventricular arrhythmia and sudden cardiac death (SCD). The rate of SCD in CKD patients increased as glomerular filtration rate decreased. Sudden cardiac death is generally mediated by ventricular arrhythmias associated with instability of myocardial repolarization. QT variability index (QTVI) as an index of myocardial repolarization instability is a strong predictor for fatal ventricular arrhythmias and SCD. The aim of this study was to evaluate correlation between QTVI and GFR(< 60 >mL/minute) in predialysis CKD patients. This study was done in Kidney and Hypertension Clinic of Dr. Hasan Sadikin Hospital Bandung, from October to December 2011. A total of 51 subjects were included in this study and had their resting electrocardiography (ECG) recorded and QTVI calculated, 94% had hypertension or received anti hypertension, while only 37% fulfilled the ECG criteria for left ventricular hypertrophy. We determined the correlation between QTVI and GFR using Spearman’s rank, with mean QTVI 0.16 (SD 0.24), we had strong and significant correlation between QTVI and GFR (r=-0.816, p <0.001) and moderate correlation between QTVI and estimated glomerular filtration rate (r=-0.460, p<0.001). In conclusions, there is a strong correlation between QTVI and GFR in predialysis CKD patients, the lower GFR the higher QTVI value. [MKB. 2012;44(4):193–98].Key words: Chronic kidney disease, glomerular filtration rate, QT variability index, sudden cardiac death DOI: http://dx.doi.org/10.15395/mkb.v44n4.214
PENGARUH RADIOTERAPI EKSTERNAL TERHADAP FUNGSI SEL RAMBUT LUAR KOKLEA PENDERITA KARSINOMA NASOFARING Nurmasari, Shinta; Samiadi, Dindy; Purwanto, Bambang
Majalah Kedokteran Bandung Vol 42, No 2
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (105.973 KB)

Abstract

Pilihan utama pengobatan karsinoma nasofaring adalah radioterapi. Pemberian radioterapi dosis tinggi menimbulkan kerusakan struktur jaringan, salah satunya adalah gangguan pendengaran. Gangguan di koklea timbul akibat kerusakan struktur sel rambut akibat degenerasi stria vaskularis, atrofi spiral ligamen, dan membran basilaris.Tujuan penelitian adalah untuk mengetahui fungsi sel rambut luar koklea akibat radioterapi penderita karsinoma nasofaring. Tipe penelitian adalah studi analitik observasional dan dilakukan di Bagian IK.THT-KL/RS. Hasan Sadikin Bandung mulai Maret sampai September 2007. Dilakukan pemeriksaan audiometri, timpanometri, danemisi otoakustik (otoacoustic emission)/OAE sebelum radioterapi, serta pemeriksaan timpanometri serta OAE saat radioterapi dan satu bulan pascaradioterapi. Untuk menguji pengaruh radioterapi eksternal digunakan uji McNemar dan uji Z. Diperoleh 42 telinga dari 27 subjek penelitian yang memenuhi kriteria inklusi. Didapat 18 lakilakidan 9 perempuan. Hasil penelitian menunjukkan insidens gangguan fungsi sel rambut luar koklea sebesar 9,6% pada dosis 2.000 cGy, 61,5% pada 4.000 cGy, 81,1% pada 6.600 cGy, dan 82,8% satu bulan pascaradiasi. Hubungan gangguan fungsi sel rambut luar koklea memberikan nilai sangat bermakna pada dosis 4.000 cGy sampai 6.600 cGy (p<0,001). Kesimpulan penelitian radioterapi eksternal penderita karsinoma nasofaring menyebabkan gangguan fungsi sel rambut luar koklea.
PREDIKTOR STRES KELUARGA AKIBAT ANGGOTA KELUARGANYA DIRAWAT DI GENERAL INTENSIVE CARE UNIT Farhan, Zahara; Ibrahim, Kusman; Sriati, Aat
Majalah Kedokteran Bandung Vol 46, No 3 (2014)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (661.235 KB)

Abstract

Terdapat anggota keluarga yang dirawat di ruang perawatan intensif merupakan situasi yang dapat memicu stres pada keluarga. Faktor yang dapat memicu stres pada keluarga meliputi, perubahan lingkungan, aturan ruangan perawatan, perubahan status emosi keluarga, perubahan peran keluarga, perubahan kehidupan sehari-hari, perubahan finansial, serta sikap petugas kesehatan dalam pemberian informasi tentang kondisi kesehatan pasien. Penelitian ini menggunakan rancangan potong lintang. Subjek penelitian sebanyak 60 orang yang mewakili keluarga saat anggota keluarganya sedang dirawat di General Intensive Care Unit (GICU) Rumah Sakit Dr. Hasan Sadikin (RSHS) Bandung periode Maret?Mei 2012. Teknik sampling yang digunakan pada penelitian ini yaitu purposive sampling. Instrumen untuk mengukur prediktor stres disusun berdasarkan kajian teori dan modifikasi instrumen baku family inventory live events, sedangkan instrumen untuk mengukur stres keluarga menggunakan Depression Anxiety Stress Scale 42. Data dianalisis menggunakan uji chi-kuadrat dan analisis regresi logistik. Hasil penelitian menunjukkan faktor perubahan lingkungan, aturan di ruang perawatan, perubahan status emosi, dan perubahan kehidupan sehari-hari memiliki hubungan yang bermakna dengan terjadinya stres (nilai p berturut-turut sebesar 0,01, 0,04, dan 0,03). Simpulan, tidak ada satu pun prediktor yang paling dominan di antara enam prediktor stres keluarga yang dapat memprediksi terjadinya stres. Diharapkan perawat mampu mendeteksi dini masalah psikologis keluarga di ruang intensif dan lebih mengoptimalkan tindakan supportive-educative dalam bentuk pemberian konseling kepada keluarga.Kata kunci: Keluarga, prediktor, stresPredictors of Stress in the Family whose Family Member was Treated in General Intensive Care Unit Hospitalization of family member in intensive care can be a trigger of stress in the family. Several factors which could create a stressful situation in a family are changes of environment, rules in the ward, changes of family emotional status, changes of family member roles, changes of daily activities, changes in financial situation and health care workers' attitude when giving information on patient?s health status. This study was a cross-sectional study. The number of subjects included in this study were 60 representing families whose member was hospitalized in the General Intensive Care Unit (GICU) of Dr. Hasan Sadikin General Hospital (RSHS) Bandung during the period of March to May 2012. The sampling technique used was purposive sampling. The instrument used to measure the stress predictors was developed based on theoretical review and modification of family inventory live events standard instrument. Meanwhile, the instrument used for measuring the family stress was the Depression Anxiety Stress Scale 42. Data were analyzed using chi-square test and logistic regression. The results of this study showed environmental changes, rules in the ward, emotional status changes and daily activity changes significantly corelated with stress (p value 0.01, 0.04 and 0.03, respectively). In conclusion, none of the 6 family predictors dominantly predicts stress. Nurses are expected to do early detection on psychological family problems in intensive care unit and optimize supportive-educative treatment in the form of counseling for family members.Key words: Family, predictors, stress DOI: 10.15395/mkb.v46n3.316
CINICO-EPIDEMIOLOGICAL PROFILE OF VITILIGO PATIENTS IN DR. HASAN SADIKIN GENERAL HOSPITAL BANDUNG Dwiyana, Reiva Farah; Marindani, Vani; Agustina, Rohana; Setiawan, Setiawan; Idjradinata, Ponpon S.; Sutedja, Endang
Majalah Kedokteran Bandung Vol 49, No 2 (2017)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (452.63 KB) | DOI: 10.15395/mkb.v49n2.1056

Abstract

Vitiligo is the most common hypopigmentation disorder; however, until now there iss no comprehensive epidemiological-clinical study of vitiligo in Indonesia. A descriptive study  using a questionnaire among vitiligo patients in Dr. Hasan Sadikin General Hospital Bandung was conducted to determine the clinical findings, socio-demographic factors, coexisting autoimmune disorders, and severity of disease. All vitiligo patients were recruited during the period of February 2012 to April 2014 from the Dermatology Outpatient Clinic of Dr. Hasan Sadikin General Hospital Bandung, as well as from the Endocrinology and Rheumatology Clinic Department of Internal Medicine; Endocrinology and Allergy and Immunology Clinics Department of Child Health; and Department  of Nuclear Medicine the same hospital. We collected data on socio-demographic profiles, clinical profile, and severity of vitiligo based on Vitiligo European Task Force (VETF). Out of 242 patients, female patients made up the majority of the patients (66.12%). In addition, most patients  wereunder 20 years (33.47%) and experienced onset of vitiligo highest in the first decade of life (29.34%). About 19.42% had positive family history of vitiligo and only 6.2% had history of autoimmune diseases. The majority of patients (77.27%) had vulgaris type of vitiligo with  head-neck (35.36%) asthe most frequent initial site of onset. Based on VETF,  the skin affected was mostly below 10% of body surface area (82.23%), i.e. staging score of between 0?5 (57.44%), and spreading score of between >0?(+5) or 68.18%. It is concluded that vitiligo most commonly occurs in females with the highest onset of under 10-years old and strong relationship with genetic predisposition.T he affected area was relatively small, despite the high spreading score. [MKB. 2017;49(2):132?8]   Key words: Clinical profile, epidemiology, vitiligo  Profil Kliniko-Epidemiologi pada Pasien Vitiligo di RSUP Dr. Hasan Sadikin Bandung   Vitiligo merupakan kelainan hipopigmentasi tersering, tetapi hingga kini belum ada penelitian epidemiologi-klinik yang komprehensif di Indonesia. Penelitian deskriptif menggunakan kuesioner dilakukan pada pasien vitiligo di Rumah Sakit Dr. Hasan Sadikin Bandung untuk mengetahui gambaran klinis, faktor sosio-demografik, kelainan autoimun yang menyertai, dan keparahan penyakit. Seluruh pasien vitiligo dari periode Februari 2012 hingga April 2014 yang berkunjung ke poliklinik Kulit dan Kelamin Rumah Sakit Dr. Hasan Sadikin Bandung, serta poliklinik: Endokrinologi dan Rematologi, Ilmu Penyakit Dalam; Endokrinologi dan Alergi-imunologi, Ilmu Kesehatan Anak; serta Kedokteran Nuklir, diikutsertakan dalam penelitian. Data yang dihimpun mencakup keadaan sosiodemografi, klinik, dan keparahan vitiligo berdasar atas Vitiligo European Task Force (VETF). Dari 242 pasien, perempuan merupakan jenis kelamin terbanyak (66,12%), usia di bawah 20 tahun (33,47%), dan awitan vitiligo terjadi pada dekade pertama kehidupan (29,34%). Sekitar 19,42% memiliki riwayat vitiligo pada keluarga dan hanya 6,2% yang memiliki penyakit autoimun. Umumnya tipe vitiligo vulgaris (77,27%) dengan predileksi pertama pada kepala-leher (35,36%). Area kulit yang terkena berdasarkan VETF ialah di bawah 10% dari body surface area (82,23%), staging score 0?5 (57,44%), dan spreading score antara >0?(+5) atau 68,18%. Simpulan penelitian ini ialah vitiligo banyak mengenai perempuan, awitan tersering pada usia di bawah 10 tahun dengan predisposisi genetik yang tinggi, serta daerah yang terkena vitiligo relatif kecil meskipun spreading score-nya tinggi. [MKB. 2017;49(2):132?8]   Kata kunci: Epidemiologi, gambaran klinik, vitiligo
Distribusi Subtipe Juvenile Idiopathic Arthritis di Bandung Ghrahani, Reni; Setiabudiawan, Budi; Sapartini, Gartika; Puspasari, Hesti
Majalah Kedokteran Bandung Vol 44, No 2 (2012)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1507.875 KB)

Abstract

Juvenile idiopathic arthritis (JIA) merupakan penyakit reumatik kronik tersering pada anak yang terjadi sebelum usia 16 tahun. Penelitian ini bertujuan mengevaluasi profil penderita yang didiagnosis JIA. Dilakukan penelitian deskriptif retrospektif terhadap penderita JIA yang datang ke Divisi Alergi Imunologi Departemen Ilmu Kesehatan Anak Rumah Sakit Dr. Hasan Sadikin Bandung pada periode Januari 2006–Oktober 2011 berdasarkan rekam medis. Didapatkan 28 penderita JIA terdiri atas 10 anak laki-laki dan 18 anak perempuan, dengan rentang usia 2–14 tahun, usia rata-rata 8,25±3,62 tahun. Sebanyak 14 penderita JIA merupakan tipe oligoartritis persisten, 6 tipe sistemik, 5 tipe poliartritis, dan terdapat 1 orang penderita poliartritis tipe dewasa. Pada pemeriksaan laboratorium, didapatkan 2 penderita dengan faktor reumatoid positif dan 14 penderita negatif. Terapi yang diberikan obat antiinflamasi nonsteroid sebagai protokol terapi standar, steroid, dan disease modifying anti-rheumatic drugs (metotreksat). Terdapat 3 penderita meninggal yang semuanya merupakan tipe sistemik. Simpulan, sebagian besar JIA merupakan tipe oligoartritis persisten, lebih banyak ditemukan pada anak perempuan dibandingkan dengan laki-laki. Kasus kematian terjadi pada JIA tipe sistemik. Sebagian besar penderita memberikan respons yang baikterhadap protokol terapi standar. [MKB. 2012;44(2):101–5].Kata kunci: Anak, juvenile idiopathic arthritis, subtipe Distribution of Juvenile Idiophatic Arthritis Subtypes in BandungJuvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in children which begin before 16 years of age. The objective of this study was to evaluate the profile of patients who diagnosed as JIA. The descriptive retrospective study was done to patients with JIA who came to Allergy Immunology Division, Department of Child Health Dr. Hasan Sadikin Hospital Bandung during January 2006–October 2011 period, based on the medical records. There were 28 patients with JIA consisted of 10 boys and 18 girls, age ranged 2–14 years, with mean age of onset of 8.25±3.62 years. There were 14 patients with persistent oligoarthritis type, 6 patients with systemic type, 5 patients with polyarthritis type and 1 patient with polyarthritis adult type. The laboratory data showed 2 patients with positive rheumatoid factor and 14 patients were negative. Non-steroidal anti-inflammatory drugs >as standard protocol therapy, steroids and disease modifying anti-rheumatic drugs (methotrexate) were used for treatment. There were 3 patients with systemic type death. In conclusions, most of JIA cases were persistent oligoathritis type, girls more than boys, and all death cases were systemic JIA. Most of cases had satisfactory therapeutic outcomes with standard protocol therapy. [MKB. 2012;44(2):101–5].Key words: Children, juvenile idiopathic arthritis, subtypes DOI: http://dx.doi.org/10.15395/mkb.v44n2.78

Page 14 of 64 | Total Record : 639

 12   13   14   15   16 

Filter by Year

2012 2025


Reset
Filter By Issues
All Issue Vol 57, No 3 (2025) Vol 57, No 2 (2025) Vol 57, No 1 (2025) Vol 56, No 4 (2024) Vol 56, No 3 (2024) Vol 56, No 2 (2024) Vol 56, No 1 (2024) Vol 55, No 4 (2023) Vol 55, No 3 (2023) Vol 55, No 2 (2023) Vol 55, No 1 (2023) Vol 54, No 4 (2022) Vol 54, No 3 (2022) Vol 54, No 2 (2022) Vol 54, No 1 (2022) Vol 53, No 4 (2021) Vol 53, No 3 (2021) Vol 53, No 2 (2021) Vol 53, No 1 (2021) Vol 52, No 4 (2020) Vol 52, No 3 (2020) Vol 52, No 2 (2020) Vol 52, No 1 (2020) Vol 51, No 4 (2019) Vol 51, No 3 (2019) Vol 51, No 2 (2019) Vol 51, No 1 (2019) Vol 50, No 4 (2018) Vol 50, No 3 (2018) Vol 50, No 2 (2018) Vol 50, No 1 (2018) Vol 49, No 4 (2017) Vol 49, No 3 (2017) Vol 49, No 2 (2017) Vol 49, No 1 (2017) Vol 48, No 4 (2016) Vol 48, No 3 (2016) Vol 48, No 2 (2016) Vol 48, No 1 (2016) Vol 47, No 4 (2015) Vol 47, No 3 (2015) Vol 47, No 2 (2015) Vol 47, No 1 (2015) Vol 46, No 4 (2014) Vol 46, No 3 (2014) Vol 46, No 2 (2014) Vol 46, No 1 (2014) Vol 45, No 4 (2013) Vol 45, No 3 (2013) Vol 45, No 2 (2013) Vol 45, No 1 (2013) Vol 42, No 3 Vol 44, No 4 (2012) Vol 44, No 3 (2012) Vol 44, No 2 (2012) Vol 44, No 1 (2012) Vol 43, No 4 Vol 43, No 3 Vol 43, No 2 Vol 43, No 1 Vol 42, No 4 Vol 42, No 2 Vol 42, No 1 Vol 41, No 4 Vol 41, No 3 Vol 41, No 2 Vol 41, No 1 More Issue