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Majalah Kedokteran Bandung
ISSN : 0126074X     EISSN : 23386223     DOI : 10.15395/mkb
Core Subject : Health,
Majalah Kedokteran Bandung (MKB)/Bandung Medical Journal publishes peer-reviewed original articles and case reports in basic medical research, clinical research, and applied medical science. This journal is published quarterly (March, June, September, and December) by Faculty of Medicine Universitas Padjadjaran. Articles are original research that needs to be disseminated and written in English. All submitted manuscripts will go through the double-blind peer review and editorial review before being granted with acceptance for publication.
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Articles 651 Documents
Skinfold Thickness and Mid-upper Arm Circumference in Pediatric Patients with Chronic Kidney Disease Suriadiredja, Siti Saqinah; Widiasta, Ahmdez; Rossanti, Rini
Majalah Kedokteran Bandung Vol 57, No 3 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.4046

Abstract

Chronic kidney disease (CKD) can impair the kidneys' capacity to manage nutrition, and any nutritional imbalances in CKD may affect the disease's progression. This study evaluated triceps skinfold (TSF) thickness and mid-upper arm circumference (MUAC) as indicators of nutritional status in children with early- and late-stage CKD at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia. A descriptive cross-sectional design was used with secondary data from the nephrology division registry collected between August 2021 and August 2022. Data analysis was conducted with Microsoft Excel. The study involved 65 participants, with 32 in the early stage and 33 in the late stage. For early-stage patients, the average TSF was 13.75 mm and the MUAC was 12 cm, while, the average TSF an MUAC in the late stage were  11.39 mm and 11.70 cm, respectively. Based on TSF percentiles, most patients fell within the normal range, whereas MUAC measurements indicated that the majority were below normal. In terms of %TSF, most early-stage patients had above-average values, whereas late-stage patients were below average. All MUAC measurements indicated below-average values for both stages. Overall, TSF percentiles suggested that most patients had adequate nutritional status; however, %TSF revealed excess adiposity in early-stage patients and deficits in late-stage patients. MUAC consistently indicated deficits across both groups.
Tummy Time and Development of 6- to 12-Month-Old Infants Titah, Marvella Graceria; Surjono, Edward; Prabowo, Johanes A. C.; Setiawan, Andy; Dewi, Rita
Majalah Kedokteran Bandung Vol 57, No 3 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.3928

Abstract

Early childhood development, particularly within the first 1,000 days of life, is a critical period. Globally, 5–16% of children experience developmental delays. This figure is higher in Indonesia with approximately 13–18% of children under five are facing growth and developmental issues. Adequate stimulation, including activities like tummy time, plays a vital role in a child's growth and development. This study aimed to investigate the correlation between tummy time and the developmental outcomes of infants aged 6–12 months. An analytical descriptive design with a cross-sectional approach was employed in this study that was conducted at Public Health Centers in North Sulawesi Province, Indonesia. Data collection involved questionnaires assessing the onset, frequency, and duration of tummy time, alongside the use of the Child Development Pre-Screening Questionnaire. With a minimum sample size of 96 respondents, data were analyzed using Spearman’s correlation. Findings indicated that performing tummy time more than 1–2 times per week, with each session lasting 6–20 minutes, was significantly associated with better developmental outcomes. However, no significant relationship was observed between early initiation of tummy time or the number of daily sessions with infant development. The study concluded that engaging in tummy time more than 1-2 times per week for 6-20 minutes per session can promote optimal infant development.
Preventing the Incidence of Severe Preeclampsia by Maintaining an Ideal Body Weight During Pregnancy Ferawati, Emi; Pritalianto, Hushat; Sepalanita, Widya
Majalah Kedokteran Bandung Vol 57, No 3 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.3992

Abstract

Preeclampsia is a pregnancy-specific disease potentially leading to complications, morbidity, and mortality. In general, obesity may cause preeclampsia through several common mechanisms. This study aimed to examine the association between obesity and the incidence of severe preeclampsia (SP) at Dr. Dradjat Prawiranegara General Hospital, Serang, Indonesia. A retrospective cohort design was used and the sample comprised of 168 parturients (84 SP and 84 non-SP subjects). Sample selection was consecutively conducted from June to November 2023, while data were analyzed using the Chi-Square test and multivariable analysis with multiple logistic regression. There was a statistically significant relationship between nutritional status and obesity in participants with SP history (p<0.05). Obese women had a 2.96 times higher risk of developing SP compared to non-obese. Additionally, the study found that multigravidas (≥G2) had a 2.19 times higher risk of suffering from SP compared to primigravidas (G1) (p=0.019). Furthermore, women who only completed ≤ junior high school education had a 2.14 times higher risk of suffering from SP compared to those who completed ≥ high school (p=0.060). In conclusion, women in delivery who suffered from obesity have a 2.68 times greater risk of suffering SP than non-obese, as evident from both bivariable and multivariable analyses.
Comparison of Sensitivity and Specificity between B.I.L.E. Criteria and Tokyo Guidelines 2018 (TG18) for Diagnosing Acute Cholangitis Pratomo, Nugroho Rizky; Rudiman, Reno; Sulthana, Bambang Am am Setya
Majalah Kedokteran Bandung Vol 57, No 3 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.4132

Abstract

Acute cholangitis is an inflammatory condition of the biliary system due to bacterial infection associated with biliary stasis or obstruction. Diagnosis is made using the Tokyo Guidelines 2018 (TG18) criteria. The biliary imaging abnormality, inflammatory test abnormality, liver test abnormality, and exclusion of cholecystitis/pancreatitis (B.I.L.E.) criteria are relatively new, with limited studies evaluating their sensitivity, specificity, and validation. This study aimed to compare the sensitivity and specificity of B.I.L.E. and TG18 criteria for the diagnosis of acute cholangitis. This is an observational analytic study with prospective cohort design during May 2023–May 2024. Data were obtained from patients who came to the Emergency Department of Dr. Hasan Sadikin General Hospital Bandung, Indonesia, with clinical symptoms of fever and jaundice, suspected of acute cholangitis. There were 95 subjects in this study. Based on B.I.L.E. criteria, 57 (60%) patients were categorized as high probability and 38 (40%) patients were categorized as unlikely acute cholangitis, while the TG18 criteria resulted in 61 (64.2%) patients classified as definite and 34 (35.8%) patients classified as suspected acute cholangitis. The sensitivity of the B.I.L.E. criteria was 92.1%, with a specificity of 94.73%. Positive Predictive Value (PPV) and Negative Predictive Value (NPV) of B.I.L.E. criteria were 92.1% and 94.73%, respectively. In contrast, the sensitivity and specificity of TG18 criteria in this study were 82.35% and 83.6%, respectively. The PPV of TG18 reached 73.68% while the NPV of TG18 reached 89.47%. In conclusion, B.I.L.E. criteria have higher sensitivity and specificity than TG18 criteria in diagnosing acute cholangitis patients.
Clinical Approach to Differentiating Epileptic Seizures from Bipolar Disorder Islamiyah, Wardah Rahmatul; Putera, Rudolph Muliawan
Majalah Kedokteran Bandung Vol 57, No 3 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.4022

Abstract

Distinguishing between epileptic seizures and bipolar disorder in clinical setting presents a significant challenge due to overlapping symptoms and the complex mechanism underlying both conditions. This study offers a novel perspective by integrating the latest research and clinical practices to explore this intricate diagnostic landscape. Unlike previous studies that primarily focused on isolated aspects, this study synthesizes recent advancements in neuroimaging, wearable technology, and machine learning to enhance diagnostic accuracy. Data sources searched were Google Scholar, PubMed, and ScienceDirect using the keywords of ‘epileptic seizures’, ‘bipolar disorder’, ‘diagnosis’, ‘neuroimaging’, ‘wearable technology’, and ‘machine learning’. Following the Preferred Reporting Item for Systematic Review and Meta-Analysis (PRISMA) methodology, the findings highlight how the variability of mood episodes and their resemblance to seizure activity often complicate differential diagnosis. Moreover, they underscore the potentials of emerging technologies, such as real-time monitoring via wearable devices and AI-driven diagnostic tools, in refining current clinical approaches. This study emphasizes the necessity of clinic awareness regarding subtle but crucial distinctions between bipolar disorder and epileptic seizures. By leveraging continuous monitoring and data-driven insights, an innovative framework that combines clinical expertise with advanced technology is proposed, paving the way for more precise and effective diagnostic methods.
Functional Outcome of Biportal Endoscopy Spine Surgery for Lumbar Disc Herniation Diseases Risdianto, Ajid; Andar, Erie; Brotoarianto, Happy Kurnia; Priambada, Dody; Muttaqin, Zainal; Prihastomo, Krisna Tsaniadi; Bakthiar, Yuriz; Arifin, Muhammad Thohar
Majalah Kedokteran Bandung Vol 57, No 3 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.4128

Abstract

Biportal endoscopic spine surgery (BESS) is an innovative, minimally invasive technique to treat lumbar disc herniation (LDH). BESS provides superior surgical visualization with minimal tissue dissection. However, its application requires a thorough understanding of endoscopic anatomy and adaptation of endoscopy equipment, which are key factors in achieving optimal functional outcomes post-surgery. This study aimed to evaluate the functional outcomes and complications of BESS performed on 49 patients between 2020 and 2022 at Dr. Kariadi Hospital, Semarang, Indonesia. The majority of patients (53%) had herniation at the L4-5 level, followed by L5-S1. Pain assessment using the Visual Analog Scale (VAS) demonstrated a significant reduction in pain, from 4.26 to 1.5, post-surgery. Functional outcomes, as evaluated using MacNab’s Criteria, revealed that 93.8% of patients achieved a satisfactory condition, with 36.7% reporting no pain and 57.1% experiencing occasional pain that did not affect their daily activities. Complications were minimal, with two cases of dural tears and intraoperative bleeding. The study concludes that BESS is a safe and effective procedure for LDH, resulting in significant pain relief and functional improvement, although certain technical challenges persist.
Closure Techniques and Postoperative Outcomes of Major Lower Limb Amputation in Acute Limb Ischemia Khadafy, Reza; Hapsari, Putie; Utomo, Hafidh Seno Radi
Majalah Kedokteran Bandung Vol 57, No 3 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.4149

Abstract

Amputation, derived from the Latin "amputare," refers to the removal of a body part covered by skin, often necessitated by acute limb ischemia (ALI). Effective wound closure is critical for minimizing complications, length of stay, costs, and the risk of re-amputation. This study compared postoperative outcomes of major lower limb amputation in ALI patients with primary versus delayed wound closure. A descriptive analytic study was conducted at Dr. Hasan Sadikin Hospital, Bandung, Indonesia, from January 2020 to December 2023, analyzing medical records of 46 patients aged 19–85 years, with a predominance of female patients. Thrombosis was the leading cause of ALI (76.1%), and hypertension was the most frequent comorbidity. Significant differences were observed in stump complications and revision surgery rates between primary and delayed wound closure groups (p<0.05), while length of stay and mortality did not show statistically significant differencesy. In conclusion, the study highlights a significant relationship between different wound closure methods and complications, suggesting that choice of closure technique may influence the postoperative outcomes in ALI patients.
Correlation Between Anemia, Sexually Transmitted Infections, and Low Birth Weight Among Pregnant Women Suprapto, Elviara Martha Tinova; Putra, Mega Memory Rahasa; Bangun, Thomas Yan; Azizah, Nur
Majalah Kedokteran Bandung Vol 57, No 3 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.4212

Abstract

Anemia in pregnancy and sexually transmitted infections (STIs) are global health issues linked to low birth weight. This study explored the correlation between these factors and low birth weight at the General Hospital of Scholoo Keyen, South Sorong, Southwest Papua, Indonesia. A cross-sectional observational analytic study was conducted from September 2022 to March 2023, involving pregnant women who gave birth at the General Hospital of Scholoo Keyen. The correlation between risk factors and low birth weight was analyzed using the chi-square test with a significance threshold of p<0.05. Results showed that among 162 pregnant women (average age: 27.72±6.62 years), anemia severity was distributed as follows:severe (3.7%), moderate (16.0%), and mild (40.1%). However, no significant relationship was found between anemia and birth weight (p=0.850, p>0.05). The incidences of HIV, syphilis, and hepatitis B were 3.1%, 13.6%, and 7.4%, respectively. A significant association was identified between HIV infection and low birth weight (p=0.000), while no such association was found for syphilis (p=0.160) or hepatitis B infection (p=0.852). In conclusion, HIV infection is associated with low-birth-weight newborns, but there are no apparent relationships between anemia, syphilis, or hepatitis B infection and low-birth-weight newborns, This study implies the importance of nutritional support among pregnant mothers with HIV and delaying pregnancy in HIV-positive women to until their immune system improve.
Tension Band Wiring for Chronic Acromioclavicular Joint Dislocations Rockwood Type III/ISAKOS Type IIIB Thaib, Subhan; Ramdani, Setiyo
Majalah Kedokteran Bandung Vol 57, No 3 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.4165

Abstract

Acromioclavicular joint (ACJ) dislocations account for 10% of shoulder injuries, with Rockwood type III being the most common. Despite its prevalence, there is no consensus regarding a gold standard surgical treatment for chronic ACJ dislocations. tients often delay seeking medical attention during the chronic phase, during which soft tissue healing capacity significantly declines. A 30-year-old male presented with persistent shoulder pain and restricted elevation two months after a motorcycle accident. The patient initially sought alternative treatment, later developed chronic pain and an inability to elevate the shoulder. Physical and radiograph examinations revealed a Rockwood type III ACJ dislocation. After treatment with the tension band wiring (TBW) technique, functional outcomes were assessed using the Disabilities of The Arm, Shoulder and Hand (DASH) and Constant scores. The Constant score improved from 61 to 92 and while the DASH score decreased from 45 to 5 in 3 months and 2 weeks post-operation. International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine (ISAKOS) subdivided Rockwood Type III injuries into IIIA (stable) and IIIB (unstable), with type IIIB requiring surgical treatment. Several studies suggested that mechanical stabilization with biological augmentation is sufficient in neglected cases. However, this technique is expensive and required specialized skill and expertise in shoulder arthroscopy. To overcome this challenge, TBW has emerged as a cost-effective and straightforward surgical technique that enables faster rehabilitation and provides a stable, pain-free shoulder without postoperative complications. It may serve as a viable treatment option, particularly in resource-limited or rural settings.
Microbial and Antimicrobial Susceptibility Profile of Pediatric Hematological Malignancy Patients at a Tertiary Hospital Adrizain, Riyadi; Sugianli, Adhi Kristianto; Kasih Pasaribu, Elisabeth Putri; Trie Utami, Fadila Dyah; Kwarteng, Alexander
Majalah Kedokteran Bandung Vol 57, No 4 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.4362

Abstract

Neutropenia is a major predisposing factor for infection in pediatric patients with hematological malignancies. In Indonesia, data on microbial patterns and antibiotic resistance in this group remain limited, highlighting the need for local data to guide empirical therapy. This study aimed to determine the microbial and antibiotic susceptibility profile of pediatric patients with hematological malignancies. A cross-sectional descriptive study was conducted in the pediatric ward of Dr. Hasan Sadikin General Hospital, Bandung, from April to June 2024. Data were collected retrospectively using total sampling from medical records and registers of patients diagnosed with hematological malignancies (subgroups I and II) between January 2021 and December 2022. Microbial identification and antibiotic susceptibility profiles were performed using an automated colorimetry method. A total of 33 bacterial isolates were identified, with Gram-negative bacteria being the most frequent (75.8%). The predominant isolates were Escherichia coli (39.4%), Klebsiella pneumoniae (15.15%), and Staphylococcus hominis (12.1%). From all isolates, 69.7% were multidrug-resistant organisms (MDROs). About 62.5% of Gram-positive bacteria were methicillin-resistant coagulase-negative Staphylococci (MRCoNS), while 48% and 24% of Gram-negative bacteria were extended-spectrum β-lactamase (ESBL) and carbapenem-resistant, respectively. Gram-positive bacteria showed 100% sensitivity to Linezolid, Tigecycline, and Vancomycin, while Gram-negative bacteria showed the highest sensitivity to Amikacin. Escherichia coli, as the most frequent isolate, showed 100% sensitivity to Tigecycline. In conclusion, Gram-negative bacteria were the predominant organisms, with Escherichia coli being the most common isolate. The antibiotic susceptibility test showed a high proportion of MDROs and decreased susceptibility levels in 2022 compared to 2021.