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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
 109   110   111   112   113 
Sebab Kematian Bayi Prematur Ditinjau dari Hasil Biopsi Post-Mortem Organ Tubuh Soeripto Soeripto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 17, No 01 (1985)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The mortality of the premature babies in Indonesia is still high. The exact cause of death is still unknown, because necropsy and pathological examination of the whole placenta are very rarely carried out. Needle biopsy of the dead premature babies' organ is expected to help in searching the cause of death. A retrospective study was performed to reevaluate the biopsied organs of the dead prema tures from October 1970 through September 1971 in the Department of Pathology, Gadjah Mada University. Yogyakarta. The result of this study shows that early neonatal death of premature babies is 80,6% of all premature death. Based on histopathological examination of lung biopsies of those dead premature babies, it is clear that atelectasis is the primary cause, congestion the second, and Hyaline Membrane Disease (HMD) the third. Biopsies of other organs could not determine the exact cause of premature deaths as yet. Key Words: premature baby - early neonatal death - needle biopsy - atelectasis - Hyaline Membrane Disease
Mekanisme kerja beberapa pestisida dan penanggulangan keracunannya pada manusia R.H.Yudono R.H.Yudono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 10, No 01 (1978)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Although the pesticides are for the purpose of killing pest ( = unwanted forms of life), they are also toxic to many non target species, including man. In fact acute or chronic poisoning by pesticides does occur. This is usually the result of occupational exposures or careless use, misuse or mishandling of the pesticides.As with the use of any potentially injurious chemical substance, the use of pesticides must take into consideration the balance of the benefits that may be expected versus the possible risk of injury to human health or to degradation of environmental quality.The prospect of mass starvation due to destruction of food crops by insects and noxious weeds compared to the question of possible injury to a few members of the population as a result of the use of insecticides may clearly indicate an advantage of pesticide use in terms of numbers of people whose health and welfare are protected. Similarly where vector borne diseases are a major threat to the health of large human populations and where the use of chemical pesticides to destroy the vectors of these diseases is a successful procedure, the application of these chemicals seems to beclearly indicated.For some groups of pesticides the mechanism of toxic action is well understood, but for others there is little or essentially no information concerning the way of intoxication.Concerning treatment, as might be expected from the current knowledge of pathogenesis, it is also not always easy CO find the right one. For this reason, if possible, we should better prevent than treat intoxication from pesticides or if we are forced to use pesticides, we must make our choice among the non-toxic pesticides or which intoxication is treatable.
Allometrical correlation of biacromial and bicristal breadth to height growth in 7-15 years old children in Bantul Regency Yogyakarta Province Janatin Hastuti Janatin Hastuti
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 36, No 1 (2004)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Changes in body measurements during growth period cause change in their proportion, and this relationship can be measured using allometrical method. Growth of biacromial and bicristal in children are specific, because they can indicate the sexual dimorfism between boys and girls. Objective: The aims of this studi are to know the relationship between growth of biacromial and bicristal breadth to growth of height in 7-15 years old boys and girls in Bantul Regency, Yogyakarta Province. Methods: Investigation was conducted in 284 children of 7 up to 15 years old which consist of 136 boys and 148 girls. The samples were divided into 9 groups and were measured on height, biacromial and bicristal breadth. The datas were analysed using allometrical method expressed by an exponential regression equation. Student-t analysis was use to determine the difference of each measurement between boys and girls at the same age.Result: The result showed that biacromial breadth grew faster proportionally to height in 7 up to 11 and 13 up to 15 year old boys, and on the 7, 8, and 10 up to 15 years old girls. Bicristal breadth grew faster proportionally to height for all groups of age. Biacromial breadth grew faster proportionally to bicristal breadth th 8 up to 9 and 13 up to 15 year old boys and 7 year old girls. Girls of 8 up to 15 years old grew slower on biacromial breadth compared to bicristal growth.Conclusions: The conclusion was biacromial and bicristal breadth grew faster proportionally to height of boys and girls for almost all of age. Biacromial breadh of boys grew faster than bicristal breadth. In contrast, biacromial breadth of girls in the same age grew slower than bicristal breadth.Key words: growth-stature-biacromial breadth-bicristal breadth-allometrical method
Predicting time of death by postmortem erythrocyte osmotic fragility test in Sprague-Dawley white mouse Beta Ahlam Gizela Beta Ahlam Gizela
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 33, No 02 (2001)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Death cases caused by crime require estimation of the time of death as a guide for searching who is the murderer. The common method has been used is by detecting hypostasis, rigidity, temperature decreasing, and decomposition. These methods are less accurate, since they are influenced by various factors. A new more accurate method is, therefore, required.Objectives: To establish a new method in predicting time of death by searching for relations between erythrocyte osmotic fragility and time of death.Methods: This research used Quasi Experiment Design. The subjects were 31 white male of mice 2 months old. The mouse blood was taken in a periodic time: ante mortem, 0, 1, 2, and 3 hours postmortem, and their erythrocyte osmotic fragility was detected by Modification Method of Osmotic Fragility Test. The reagent used was Saline Buffer Phosphate in gradual concentration, 0.2%, 0.3%, 0.4%, 0.5%, and 0.6%.Results: Data taken from this research were analyzed by regression analysis and ROC curve analysis.There was a significant positive correlation between time of death and erythrocyte osmotic fragility (r2 = 0.536, p< 0.01). Erythrocyte osmotic fragility of 0.5% (under curve area=0.826, p<0.01) was a cut off point at 1.5  hours post mortem (MSS=154.4%).Conclusion: Post mortem erythrocyte osmotic fragility test have a value in predicting time of death.Erythrocyte osmotic fragility test of 0.5% occured at      1.5  hours post mortem.Keywords: time of death - post mortem - erythrocyte osmotic fragility
Perinatal death risks of primipara at five District hospitals in Yogyakarta Haksari EL Haksari EL
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 33, No 04 (2001)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Perinatal death in Indonesia is still high and seems to be difficult to decrease. Beside the characteristics of fetus, neonates, social and environment, there are some maternal characteristics which may increase the risk of perinatal death.Objectives: To identify the risk factors of perinatal death on primipara and multipara.Methods: The data were collected from five district hospitals in Yogyakarta during 1995-1998. The maternal and birth outcome were studied as risk factors of perinatal death.Results: Analysis of multivariate logistic showed primipara aged 5 19 years old had increased Odds ratio (OR) twice as much; prolonged OR stagnated labour and other complications during delivery had increased OR three times as much, haemorrhage had increased OR four times, low birthweight had OR of 3.01 (2.05 -4.43) and preterm had OR 4.15 (2.76-6.16) for perinatal death. Low education and twin of primipara had increased OR twice and three times respectively in univariate analysis. Multipara had increased OR and death of multipara had OR 7.7 (2.0-29.3) for perinatal death.Conclusion: There was a strong association between haemorrhage of delivery, low birth weight and preterm on primipara and perinatal death. Death of multipara had increased OR for perinatal death.Keywords: perinatal death - risk factors - primipara - multipara - district hospital
The Impact of Brain Technology on Mankind' Soedjono Aswin Soedjono Aswin
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 23, No 03 (1991)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Pemahaman dan penguasaan manusia atas proses-proses dan hukum-hukum lisis dan kimiawi, serta dasar-dasar biokimiawi dan biolisis proses-proses kehidupan, memberinya kemampuan yang seolah-olah tidak terbatas untuk memodifikasi gena, pikiran, emosi dan perilaku manusia. Perkembangan dan kecenderungan teknologi otak pada saat ini telah membangkitkan perhatian dan sekaligus kecemasan. Kemungkinan penerapan praktis teknologi otak dalam menanggulangi berbagai masalah klinis dan sosial senautiasa dilekati oleh dampak medic, hukum, etis dan sosial, baik positif maupun negatif.Teknologi otak memberi manusia kemampuan dan potensi untuk mengubah perilaku manusia dan keberadaannya di muka bumi ini, potensi merekayasa speciesnya sendiri, karena teknologi otak dapat dirancang untuk memodifikasi sifat-sifat dasar manusia. Dengan teknologi otak ini, di tangan manusia terletak kemampuan menembus, menyelidiki dan bahkan mengendalikan berbagai mekanisme pengendalian yang terdapat di dalam otaknya sendiri. Walaupun demikian, apa yang dapat dilakukan manusia tidak berarti boleh dilakukan. Masih banyak aspek kehidupan lain yang harus dijunjung tinggi dan dipertimbangkan sebelum melangkah,yaitu aspek-aspek moralitas, etis. dan religius, jika integritas manusia dan keberadaan speciesnya di planet bumi ini ingin dipertahankan.Key Words: brain technology - behavior - genetic engineering - psychotechnoiogy - morality
Clinical features of outpatients with allergic rhinitis at E.N.T. department, Faculty of Medicine, Gadjah Mada University/Dr. Dardjito General Hospital Yogyakarta Supomo Sukardono Supomo Sukardono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 28, No 01 (1996)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Clinical study was conducted on allergic rhinitls in ENT Department, DR. Sardjito Hospital for one year. The study included incidence, clinical symptoms, other test, and other treatment. The treatment having been conducted included allergen, desensitization and symptomatic therapy. Symptomatic therapy and allergen avoidance were the most often done
Phototoxicity inhibition effect of vitamin c and glutathione against several photosensitizers Rosmelia Rosmelia
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 35, No 3 (2003)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Ultraviolet B radiation on the skin, in the presence of photosensitizers such as quinolones, sulfacetamide, and non-steroid antiinflammatory.could induce phototoxicity due to cell membrane photo-oxidation. Antioxidants, such as vitamin C and glutathione, have been reported capable to neutralize free radicals and prevent oxidative reactions. Scientific report about the role of such antioxidants in the prevention of phototoxicity due to photosensitizers on above, is still limited.Objectives: To compare phototoxicity inhibition effect between vitamin C and glutathione and phototoxicity potency of several photosensitizersMaterials and Methods: A simple experimental design is used to compare phototoxicity potency of 0.08 mg/ml ofloxacin, 0.004 mg/ml furosemide, and 0.02 mg/ml ketoprofen, and effects of 0.2 mg/ml vitamin C, and 0.12 mg/ml glutathione on phototoxicity reactions of erythrocytes exposed to 1.6 J/cm2 UVB. Phototoxicity reaction was measured by hemoglobin released by targeted erythrocytes using spectrophotometer.Results: Hemoglobin released by photosensitizers were ofloxacin 6.760±.1.669, furosemide 6.532±1.271, ketoprofen 6.710 ±1.826 g/dI respectively. There was no significant difference of haennoglobine released among them (p>0.051. Addition of vitamin C could reduce phototoxicity of photosensitizer very significantly (p
Evaluation of in vitro culture media of adult Brugia malayi with glucose supp/ementetipn Sri Sumarni Sri Sumarni
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 31, No 03 (1999)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: The circulating antigen of filariasis malayi patient is the excretory/secretory (ES) protein. It was used as antigen in monoclonal antibody production. The ES protein can be obtained by in vitro culture of filarial worm Brugia malayi.Objective : The aims of this research was to evaluate in vitro culture media with glucose supplementation of adults B.malayi to obtain the ES protein maximally.Methods: Adult males and females B.malayi were cultivated in vitro in medium with glucose supplementation in different concentrations (1%, 3% and 5%). The culture media were changed daily and analysis of its protein were carried out quantitatively using Bradford method, and gel electrophoresis (SDS PAGE) for qualitative protein analysis. The cuticle of adults B.malayi were extracted by detergent cetyltrimethyl ammonium bromide (CTAB).Results: The effective culture medium was RPMI with 1% glucose supplementation to produce ES protein maximally, and longevity of worms could survive for 6 days. The quantitative protein concentration of female worms culture medium was 0.2-1.85 ug/ml, and the protein molecular weight of female worms cuticle was 26 kDa- 116 kDa. The protein concentration of male culture medium was 0.2-0.5 ug/ml, the molecular weight of adult male cuticle protein was 34 kDa- 56kDa. The peak concentration of protein in both cultivation was observed on the third day.Conclusion: The best medium for in vitro cultivation of adults B.malayi was RPMI with 1% glucose supplementation. The protein concentration of the female culture media was higher than male .Key words: glucose supplementaion - in vitro culture - filarial worms -Brugia malayi - ES protein
Professionalism and humanitarianism in health care delivery Teuku Jacob Teuku Jacob
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 22, No 03 (1990)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

This article defines professionalism relevant to the medical profession and the trend towards deprofessionalization in medicine. Subsequently humanitarianism is described, followed by the nature and causes of dehumanization in medicine. Rehmnanizing efforts are expected to be enhanced by certain on-going trends in the society.The author further presents the issue of human rights, both natural and cultural, and their relation to the right to health care, whence patient rights developed. In this connection the problem of justice in the allocatiOn of health resources is encountered.Private medical practice in itself does not interfere with either professionalism or humanitarianism as long as distributive justice and patient rights arc observed.Lastly, potential future problems related to medical professionalism and humanitarianism are brought into focus, such as the growing urban slums, rural poverty, and opportunity for practice and employment. It is emphatically noted that sporadic medical interventions among underserviced communities are not effective, except from the vantage point of publicity.Key Words: medical professionalism - patient rights - justice in medicine 7 dehumanization - private practice

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