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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
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The effect of moderate intensity physical exercise on the body fat percentage in elderly women Santosa Budiharjo, Santosa Budiharjo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 36, No 4 (2004)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Postmenopausal women tend to increase the body fat percentage. A decline in estrogen level cause decrease in lipolytic process.Objective: To know the effect of moderate intensity physical exercise on body fat percentage in elderly women.Method: Pretest and posttest control design. A total amount of thirty, healthy women, 60-70 years old, was divided into three groups. The first group was treated by exercise three times a week, the second group was treated by exercise two times a week and the third group was a control group. The exercise used was D series of fitness dance for elderly created by PERWOSI Yogyakarta which is a low impact aerobic dance with moderate intensity (70-79 % maximal heart rate), 40-54 minutes/day for eight weeks.Result: The result showed that the first group revealed a significantly decrease in body fat percentage (p< 0.05). The second group revealed decrease no statistically significant in body fat percentage (p> 0.05), however there was a significant correlation between the duration of exercise and the body fat percentage (r = -0.9042).Conclusion: The low impact aerobic dance with moderate intensity, 40-54 minutes/day, three times a week, for eight weeks decreased body fat percentage.Key words: moderate intensity low impact aerobic dance - excercise frequency - body fat percentage -elderly women
S.T.S. dan Masalah Diagnose Syphilis Soedarmadi, Soedarmadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 6, No 04 (1974)
Publisher : Universitas Gadjah Mada

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Abstract

The Wassermann, Kahn and VDRL reactions are usually done routinely. A diagnosis based sorely on STS reaction is not recommended, although all of the three reactions are positive, moreover a diagnosis based only on one positive STS reaction is of small significant without clinical diagnosis and history of suspected syphilis. Non-specific STS is better for routine testing and for screening, as it is more sensitive while specific STS is better for solving diagnostic problems.Arti singkatan-singkatan yang dipakai :CWR = Cardiolipin Wassermann ReactionVDRL = Veneral Disease Research LaboratoryRPR = Rapid Plasma ReaginRPCF = Reiter Protein Complement FixationKRPA = Kolmer with Reiter Protein AntigenTCF = Treponema pallidum Complement • FixationT C P = Treponema pallidum Cryolysis ProteinTPA = Treponema pallidum AgglutinationTPHA = Treponema pallidurn aem-AgglutinationTPI Treponema pallidum ImmobilizationFTA Fluorescent Treponemal AntibodyABS = Absorption
CT scan examination on stroke patients Arif Faisal, Arif Faisal
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 23, No 04 (1991)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

This study was conducted in patients with clinical stroke. The results showed that 61.3% patients had cerebral infarction, 33.0% hemorrhagic lesions and 5.7% was normal by CT scan examination. 12 of 29 hemorrhagic lesionswere associated with in [raven tri cular bleeding and these lesions have a poor prognosis.The cerebral infarctions were located mostly in capsula interna and nucleus le n tiforrnis, but the thalamus and capsula interna demonstrated as the main location for hemorrhagic lessons. The usefulness of CT scan in stroke lies especially in detecting the location, extension of lesion and in differentiating between ischemic and hemorrhagic lesions.Key Words: CT scan - in traventricular bleeding - hem iparesis - cerebral infarction - stroke
Peranan Diagnostik Teknik Imunofluoresensi Dalam Dermatologi Hardyanto, Hardyanto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 12, No 03 (1980)
Publisher : Universitas Gadjah Mada

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Abstract

Diagnostic procedures by means of immunofluorescence techniques have been greatly used in investigations of some diseases which have immunologic background. These tests are now accepted as routine diagnostic procedures in dermatology in advanced countries beside electron microscopy. The main purpose of this paper is to summarize intelligibly immunofluorescence results obtained so far in various skin disorders. The methods of application can be divided into direct and indirect method.The basic principle, technical procedures, some problems and application of immunofluorescence on various skin diseases are discussed.Key Words: immunofluorescence techniques - direct and indirect immunofluorescence -- antigen-antibody tracing - immunologic skin diseases - dermatoses
Kadar amonia dan urea darah bayi prematur pada usia minggu pertama Purnomo Suryantoro, Purnomo Suryantoro
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 28, No 01 (1996)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Ammonia and urea blood levels in premature infants during the first week of life were analyzed. Twenty seven blood samples from premature infants at the age of 1, 3 and 7 days were collected. The concentration of ammonia was determined using Amitest meter (TSUGAI), while the urea concentration was measured using regular techniques. Even though the ammonia levels did not exceed 180 pg/d1., the data showed that the critical situation occur in the first three days of life when the ammonia concentration was the highest and urea was also concentrated. This condition releaved in day seven.Key words : ammonia level - urea level - premature baby - enzyme deficiency - hyperammonemia
Displacement of bilirubin from human albumin by drugs Achmad Surjono, Achmad Surjono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 02 (1986)
Publisher : Universitas Gadjah Mada

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Abstract

The displacing effect of 18 commonly used drugs on bilirubin-albumin binding were studied quantitatively. The competitive results of certain concentrations of drugs were measured by peroxidase oxidation method on standard bilirubin-albumin solution (bilirubin 0.255 mmol, albumin 0.45 mmol. bil /alb 0.56). Sulfisoxazole, the known clinically potent bilirubin-displacer was used as control. The apparent binding constant to the high-affinity site of albumin (Kd) of mephenamate (1.4 X 105), indomethacin (1.23 X 105), diflunisal (8.4 X 104), diazepam (6.7 X 104) and furosemide (3 X 104) were stronger than sulfisoxazole (1.72 x 104). Latamoxef, aminophylline and cefalotin were slightly lower than sulfisoxazole. The maximal displacing factors (MDF) were also determined, whereas sulfisoxasole was 2.29. Taking the MDF 1.2 as the upper limit for significant danger of displacement, mephenamate (4.02), latamoxed (1.63) and diflunisal (1.24) showed a higher risks Moderate to slight risks of displacement were recorded on indomethacin, cevalotine, cefotaxime, acetyl salicylic acid, aminophylline, phenobarbital, furosemide and ampicillin. No possible bilirubin-displacer were shown by sulir. idac, diazepam, doxapzam, digoxin, amikacin, gentamicin and kanamycin. Caution and substitution should be considered in giving non-steroid and-inflammatory drugs for closure of patent ductus arteriosus and latamoxef for sepsis in premature infants because of their potential risk of bilirubin encephalopathy. Key Words: albumin-bilirubin-binding drugs - displacing effect - kernicterusanti-inflam matory drugs - bilirubin encephalopathy
Bone scanning study with Tc-99m-MDP for screening of malignant metastasis in patient with lung carcinoma Bagaswoto Poedjomartono, Bagaswoto Poedjomartono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 22, No 01 (1990)
Publisher : Universitas Gadjah Mada

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Abstract

Bone scanning study with Tc-99m-MDP is usually used for screening of malignant metastasis. This method is not invasive, very sensitive but not specific. Indications of bone scanning study are detecting metastasis, evaluation of therapy and follow up the disease. The dosis of Tc-99m-MDP is 15 mCi injected into vena cubiti and after 2-4 hours, scanning will be done. Metastatic lesions are indicated by hyperactive areas on the bone. This scanning is done for evaluation how far the bones are involved in patients with lung carcinoma.Key words: lung carcinoma - bone metastasis - Tc-99m-MDP scanning - radiology - oncology
Mekanisme kerja beberapa pestisida dan penanggulangan keracunannya pada manusia R.H.Yudono, R.H.Yudono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 10, No 01 (1978)
Publisher : Universitas Gadjah Mada

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Abstract

Although the pesticides are for the purpose of killing pest ( = unwanted forms of life), they are also toxic to many non target species, including man. In fact acute or chronic poisoning by pesticides does occur. This is usually the result of occupational exposures or careless use, misuse or mishandling of the pesticides.As with the use of any potentially injurious chemical substance, the use of pesticides must take into consideration the balance of the benefits that may be expected versus the possible risk of injury to human health or to degradation of environmental quality.The prospect of mass starvation due to destruction of food crops by insects and noxious weeds compared to the question of possible injury to a few members of the population as a result of the use of insecticides may clearly indicate an advantage of pesticide use in terms of numbers of people whose health and welfare are protected. Similarly where vector borne diseases are a major threat to the health of large human populations and where the use of chemical pesticides to destroy the vectors of these diseases is a successful procedure, the application of these chemicals seems to beclearly indicated.For some groups of pesticides the mechanism of toxic action is well understood, but for others there is little or essentially no information concerning the way of intoxication.Concerning treatment, as might be expected from the current knowledge of pathogenesis, it is also not always easy CO find the right one. For this reason, if possible, we should better prevent than treat intoxication from pesticides or if we are forced to use pesticides, we must make our choice among the non-toxic pesticides or which intoxication is treatable.
The Effects of new T cell line derived lymphokines on B cell activation Sofia Mubarika Haryana, Sofia Mubarika Haryana
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 27, No 01 (1995)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Telah diketahui bahwa untuk aktivasi limfosit B diperlukan faktor pertumbuhan yang disebut limfokin atau sitokin. Banyak bukti menunjukkan bahwa limfosit T yang teraktivasi menghasilkan substansi yang dapat memacu proliferasi atau diferensiasi limfosit B. Dewasa ini telah dapat diidentifikasi berbagai limfokin yang disebut sebagai interleukin (IL) seperti IL-2, IL-3, IL-4, IL-5, IL-6 dan IL-7 yang ikut berperan dalam aktivasi sel B. Namun, mekanisme aktivasi sel B oleh limfokin sampai sekarang masih terus berkembang dan dipelajari. Untuk dapat lebih memahami aktivasi sel B, dalam penelitian ini telah dilakukan pembuatan suatu T cell line, dan telah dikarakterisasi, yakni menunjukkan fenotipe Thyl+, Lyt1+2+, Dalam penelitian ini berbagai aktivator poliklonal lipopolysaccharide (LPS), ConA, dextran sulfat dipakai untuk memacu T cell line menghasilkan limfokin. Aktivitas limfokin pada supernatannya kemudian dianalisis dengan menggunakan blastogenesis assay dengan 3H-thymidine dan hemolytic plaque assay.Hash penelitian menunjukkan bahwa T cell line menghasilkan faktor pertumbuhan yang memacu proliferasi sel B (B cell growth factor II = BCGF II atau IL-5) dan faktor yang memacu sel B untuk berdiferensiasi (B cell differentiating factor = BCDF atau IL- 6) dan menghasilkan igM dan IgG.Key words : blastogenesis assay -- hemolitic plaque assay -- B cell activation -- T cell line -- lymphokines
Determinants of immunization coverage in Yogyakarta Province Syarifah Hanum, Syarifah Hanum
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 03 (2005)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Children and infant immunization are often viewed as the symbol of preventive medicine and health service. Furthermore, immunization coverage is often used as an indicator of health service achievement. Recognizing the determinants associated with infant and children immunization status is one of the efforts to increase immunization coverage.Objectives: To know the immunization coverage in Yogyakarta province and determinants associated with coverage and age on immunization.Materials and methods: This is a cross-sectional study on children 12-23 months of age living in Yogyakarta municipality and other four districts in Yogyakarta province. Subjects were selected using proportional probability multistage cluster random sampling from 30 clusters each representing rural and municipality as urban area.Results: The coverage in municipality as well as in urban areas exceed 90%. The coverge is too high to allow analysis on unimmunized children. We found no statistically significant difference of coverage between rural educational level and though there was a significant difference in parental educational level and occupation distance to nearest health center and age on immunization (p>0.05). There is a statistically significant difference between age on BCG and hepatitis B immunization with place of immunization (p<0.05).Conclusion: Immunization coverage in Yogyakarta province based on survey exceeded 90%. Determinant associated with age on immunization was place of immunization.Key words: immunization coverage - determinant - age on immunization. 

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