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e-Journal Pustaka Kesehatan
Published by Universitas Jember
ISSN : 2355178X     EISSN : 27213218     DOI : -
Core Subject : Health, Science,
Health Professions Library & Information Science
e-Journal “Pustaka Kesehatan” merupakan jurnal elektronik ilmiah berISSN (ISSN: 2355-178X) yang menerbitkan artikel hasil penelitian di bidang kesehatan secara umum meliputi: Kedokteran, Kedokteran Gigi, Kesehatan Masyarakat, Farmasi, dan Ilmu Keperawatan. Artikel yang dikirim belum pernah dipublikasikan atau tidak dalam proses penerbitan dalam jurnal ilmiah lain. e-Journal “Pustaka Kesehatan” diterbitkan tiga kali dalam setahun, yaitu bulan Januari, Mei, dan September.
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Articles 30 Documents
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Search results for , issue "Vol 4 No 1 (2016)" : 30 Documents clear
Kadar Serum Glutamic Oxaloacetic Transaminase (SGOT) pada Tikus Wistar (Rattus norvegicus) Jantan yang Dipapar Stresor Rasa Sakit Electrical Foot Shock selama 28 Hari (The Level of Serum Glutamic Oxaloacetic Transaminase (SGOT) in Male Wistar Rat (Ratt Nur Lely Yaumil Qodriyati; Erna Sulistyani; Budi Yuwono
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

  Stress is a natural reaction that allows the human compelled to face the difficulties. Stimuli that causes stress can be physical and psychological. Physical stressors can occur continuously or sustained, which causes pathological processes in the body. This pathological process may be occur in liver and heart. One of parameter to assess characteristics of tissue can use Serum Glutamic Oxaloacetic transaminase (SGOT). The aim of this study was to prove differences level of SGOT in male Wistar rats (Rattus norvegicus) that exposed and control group were not exposed by pain stressor electrical foot shock for 28 days. Blood sampling was carried out on day 28 in intracardiac then tested the levels of SGOT. Statistical analysis showed that there was no significant change (p≤0,05) between control and treatment group. Liver damage from stressors may be not cause necrosis of liver cells. SGOT was not a single biomarker that was specific and sensitive for the diagnosis of liver disease because SGOT was also found in the heart.   Keywords: electrical foot shock, SGOT, stress
Pengaruh Pemberian Kitosan Cangkang Udang Putih (Penaeus merguiensis) terhadap Ketebalan Trabekular Femur Tikus Wistar Betina Pasca Ovariektomi (The Effect of White Shrimp (Penaeus merguiensis) Shells Chitosan on the Trabecular Thickness of Femoral Fem Suci Rizalah I; Muhammad Hasan; Septa Surya Wahyudi
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

There are low bone density and defects in bone micro-architecture which led to a significant increases of bone fragility and bone fracture in osteophorosis, due to an oestrogen deficiency in post-menopause woman. Natural polymer which has potential action on bone remodelling is chitosan. Chitosan can reduce the production of IL-1, IL-6, TNF-α and PGE2 osteoclast cell as well as increase osteoblast cell differentiation in bone formation process. The study aimed to determine the effect of chitosan white shrimp shell on the trabecular thickness of femur female wistar rats post-ovariectomy. This research was the quasy experimental laboratory research using female wistar rats that were divided into three groups; a non-ovariectomy as control, a negative ovariectomy, and an ovariectomy treatment group that was given chitosan 0,05 g/day. After 14 days, the experimental mice were euthanized and trabecular thickness was measured. There were 59,53µm, 32,44µm and 78,43µm trabecular thickness in the control group, the negative control group and the treatment group, respectively. The data were analysed using one way ANOVA and they showed a significant differences between all groups (p=0,000). It can be concluded that the chitosan of white shrimp shell can significantly increase trabecular thickness femur female wistar rats post-ovariectomy. Keywords: Osteoporosis, Chitosan, Ovariectomy, Trabecular Thickness
Gambaran Proses Kegiatan Pos Pembinaan Terpadu Penyakit Tidak Menular di Puskesmas Sempu Kabupaten Banyuwangi (The Description of Activity Process for the Integrated Development Post of Non-Communicable Disease (IDP of NCD) at Sempu Public Health Centre i Emi Dwi Astuti; Irma Prasetyowati; Yunus Ariyanto
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Sempu Public Health Centre (PHC) where the IDP of NCD activity was only applied under 1% in 2014 which the fact remains that Sempu PHC ironically is the first PHC which has IDP of NCD in Banyuwangi regency. This research aimed to find out how Posbindu PTM Al-Mubarok activity worked in Sempu PHC. This research used descriptive study with qualitative data supported. The informants of this research were purposively taken which included coordinator surveillance of Health Department in Banyuwangi regency, coordinator IDP of NCD, midwife, nurse, two cadres, the work partners and two IDP of NCD members. This research collected the data by doing interview, attentive observation and triangulation technique. Then, the data gathered were analyzed descriptively. The result showed that activity process of Posbindu PTM Al-Mubarok in Sempu PHC was different with IDP of NCD guidelines. The process did not go well because of the input which included the insufficient of human resources, incomprehensive and minimal training, insufficient of equipments, the lack of public awareness, the financial dependence and the implementation method which was not regularly conducted every month. Keywords: process, IDP of NCD
Efek Stresor Rasa Sakit Renjatan Listrik terhadap Limfosit dan Makrofag pada Gingiva Tikus Sprague Dawley (The Effect of Electrical Shock Stressor on Lymphocytes and Macrophages in Gingival Tissue of Sprague Dawley Rats) Vananda Duanta Kantasa; Banun Kusumawardani; Herniyati .
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Background: Stress has negative impact for oral health and can cause periodontal disease, because the secretion of cortisol increase when stress occur. The excessive secretion of cortisol assumed to decrease the number of lymphocytes and macrophages in gingiva which play a role on immunity of oral health. Objective: To determine the effect of electrical shock stressor on the number of lymphocytes and macrophages in gingival tissue of Sprague Dawley rats. Methods: Sprague Dawley rats were given electrical shock for 7 days (S1), 14 days (S2), and 28 days (S3). Lymphocytes and macrophages observed on histological preparation in interdental gingiva between first molar and second molar used binocular microscope, 1000x magnification. Result: The results showed that the number of lymphocytes in S1 group (3,67±0,816), S2 (3,83±0,752), and S3 (3,17±0,527), also macrophages in S1 group (0,83±0,752), S2 (1,00±0,894), and S3 (0,67±0,816) were lower than the number of lymphocytes (0,67±0,816) and macrophages (2,00±0,632) in control group. The number of lymphocytes (p = 0,002) and macrophages (p = 0,033 ) had significant difference between groups. Conclusion: The electrical shock stressor decreased the number of lymphocytes and macrophages in gingival tissue of Sprague Dawley rats that could cause the oral cavity risk to periodontal infection.   Keywords: electrical shock stressor, gingiva, lymphocytes, macrophages, stress
Pengaruh Ekstrak Metanol Daun Kayu Kuning (Arcangelisia flava (L.) Merr.) terhadap Kadar Kolesterol Total dan Trigliserida Tikus Hiperlipidemia (The Influence of Methanol Extract of Yellow Root (Arcangelisia flava (L.) Merr.) Leaves on Total Cholesterol Putri Eka Maryani; Evi Umayah Ulfa; Ema Rachmawati
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Hyperlipidemia is heterogeneous disorder that characterized by elevated levels of total cholesterol, low density lipoprotein (LDL), very low density lipoprotein (VLDL), triglyceride, and decreased levels of high density lipoprotein (HDL). The aim of this study was to determine the ability of methanol extract of leaves of Arcangelisia flava to decrease total cholesterol and triglyceride in some variations of dosage. Five groups experimental animal (each consisting of 4 rats) which have been induced by high fat and fructose diet for 45 days, followed by oral treatment of extract at a dose of 250 mg/kg BW, 500 mg/kg BW, 750 mg/kg BW, simvastatin 0.36 mg/200 g BW (control (+)), and CMC Na 1% (control (-)) for 7 days. The blood was taken on day 8, then was measured the total cholesterol and triglyceride. The test results showed that extract could decrease total cholesterol and triglyceride in line with increasing doses. According to ANOVA, there are significant differences between treatment groups (p
Uji In Vitro Efek Ekstrak Etanol Biji Kakao (Theobroma cacao) sebagai Antibakteri terhadap Propionibacterium acnes (In Vitro Test of the Effect of Cocoa Beans (Theobroma cacao) Ethanolic Extract as an Antibacterial against Propionibacterium acnes) Ariska Nur Aida; Enny Suswati; Misnawi Misnawi
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Acne vulgaris is a chronic inflammatory disease of the pilosebaceous follicle, characterized by comedones, papules, pustules, cysts and nodules in certain sites of predilection, such as face, neck and back. Propionibacterium acnes are the most recognized bacteria as a key factor for the development of acne. The purpose of this research was to identify the antibacterial effect and Minimum Inhibitory Concentration (MIC) of ethanolic extract of Cocoa beans (T. cacao) against the growth of P. acnes by in vitro method. Antibacterial activity was measured by disk diffusion (Kirby Bauer) method. This was a quasi-experimental with posttest only control group design. Samples used was colony of P. acnes. Concentration of test solution used was 7.81; 15.62; 31.25; 62.50; 125; 250; 500; and 1000 mg/ml. Positive control used clindamycin suspension and negative control used sterile distilled water. By direct measurement, MIC was obtained at the dose of 31.25 mg/ml, by using linier regretion statistical analysis, the quantitatif MIC showed at the dose of 16.93 mg/ml. Analysis using ANOVA showed significance value p=0.000 (p<0.05). In conclusion, ethanolic extract of Cocoa beans had an antibacterial effect on P. acnes by in vitro method.   Keywords: antibacterial effect, cocoa beans, Propionibacterium acnes
Pengalaman Keluarga dalam Pemenuhan Kebutuhan Perawatan Diri pada Orang Dengan Gangguan Jiwa (ODGJ) dengan Pasung di Kecamatan Ambulu Kabupaten Jember (The Family Experience in Fulfilling the Needs of the Self-care of People with Chronic Mental Health Ill nuriyah halida; Erti Ikhtiarini Dewi; Hanny Rasni
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Every problem of psychiatric nursing that may occur in seclusion of people with chronic mental health illness (ODGJ) is self-care. Self-care is one of the basic human abilities to meet his needs in order to survive, be healthy and be prosperous in accordance with the health condition. Family is an important part in motivating during the care and in treatment of ODGJ. This research aimed to describe the family experience in meeting the need of self-care in ODGJ by seclusion. The research used qualitative design with phenomenological study approach. The sampling technique used purposive sampling and snowball sampling. This research experienced a data saturation in the sixth participant, so the number of participants in this research was 6 people. The results found 12 research themes, that is, the fulfillments of self-care in: eating, air, bathing, hair cutting, dressing, defecation, rest and sleep, drinking and social interaction, inability to fulfill the task of development ODGJ, the implementation of seclusion on ODGJ and therapy for ODGJ. The need of ODGJ’s self-care by seclusion can be met by active role of family, community and health services for treatment.   Keywords: family, self-care treatment, people with chronic mental health illness (ODGJ) with seclusion
Peran dan Fungsi Kader, Dukungan Sosial Suami, dan Pengetahuan Tentang Budaya Keluarga pada Pelaksanaan Keluarga Sadar Gizi (Roles and Functions of Cadre, Husband Social Support, and Knowledge of Family Culture on the Implementation of Nutrition Conscious Ika Murni Saputri; Sulistiyani Sulistiyani; Ninna Rohmawati
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Family that is aware of nutrients is family that all members having good nutrition behavior. Pesanggaran was first place in Banyuwangi which has the lowest of implementation nutrition conscious family, it was 43,3%. The purpose of this study was to analyze the correlation between roles and functions of cadre, husband social support, and knowledge of family culture with the implementation of nutrition conscious family which was held July-August 2015 and used cross sectional approach. The research sample consists of 80 families. The result showed implementation of nutrition conscious family in region of Pesanggaran Public Health Centre was 35%. Based on bivariate analysis, it was found that roles and functions of cadre in the increasing in maternal health, baby, toddler, and socialization Kadarzi, husband social support (emotional, award, instrumental, infoemative), and knowledge of family culture had a significant relationship with the impleentation of Knutrition conscious family.The role and function of cadre in a socialization Kadarzi was the most dominant factor related to implementation of Knutrition conscious family on the family of toddler. Keywords: Kadarzi, toddler, risk factor
Daya Antibakteri Infusa Daun Asam Jawa (Tamarindus indica Linn) terhadap Streptococcus mutans (Antibacterial Activity of Asam Jawa Leaf Infuse (Tamarindus indica Linn) against Streptococcus mutans Anggi Faradiba; Achmad Gunadi; Depi Praharani
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Background: Dental caries is a mouth diseases caused by the interaction of host, microorganisms, substrate and time. One of the microorganisms that had played a role in occurrence dental caries is Streptococcus mutans bacteria. Infection caused by S. mutans can be treated with an natural antibacterial or synthetic antibacterial, but synthetic antibacterial has side effects in long term use so we need to do some research to find out natural materials that can be used as an antibacterial to minimize the side effects. Asam jawa leaf (Tamarindus indica L) is one of medicinal plants that have been known contains antibacterial compound namely flavonoid, saponin, alkaloid, vitamin C, chlorine and tanin. Objective: Determined the antibacterial activity of asam jawa leaf infuse against S. mutans. Methods: Laboratories experimental with post test only control group design research. Samples in this research divided into 2 control groups that is negative control (sterile aquadest), positive control (chlorhexidine) and 3 treated groups that is 25%, 50% and 100% asam jawa leaf infuse with 5 total samples for each groups. The antibacterial test was paper disc diffusion method. Antibacterial activity showed by the inhibition zone around the paper disc that indicated there is no bacterial growth. Result and Conclusion: Asam jawa leaf infuse had antibacterial activity against S. mutans and the effective concentration of the asam jawa leaf infuse which had antibacterial activity was 100%. Keywords : Antibacterial, asam jawa leaf infuse, S. mutans.
Optimasi Kombinasi Polietilen Glikol dan Polivinilpirolidon sebagai Bahan Pembawa pada Dispersi Padat Glibenklamid dengan Desain Faktorial (Optimization of Polyethilen Glycol and Polyvinylpirolidone Combination as the Carrier in Glibenclamide Solid Disp Hendra Kurniawan; Budipratiwi Wisudyaningsih; Dwi Nurrahmanto
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Glibenclamide is a second-generation sulfonylurea which indicated for the treatment of type II diabetes mellitus. Glibenclamide included in class II of BCS, a drug that have a good permeability but low in solubility. One of techniques that can be used to increase the solubility of glibenclamide is solid dispersion technique. This study was aimed to determine the effect of PEG 6000 and PVP K-30 combination on the melting point of solid dispersion, release of glibenclamide in solid dispersion and the optimum composition of their combination with factorial design method. Melting point response tested using melting point apparatus and percent release response tested by in vitro dissolution test. The results showed that increasing PEG 6000 and PVP K-30 will decrease melting point response and increase percent release response. The optimum composition of those combination was 700 mg of PEG 6000 and 1000 mg of PVP K-30 which provided the smallest melting point at 159,333oC and greatest release as 97.9067%. The optimum composition was characterized using FTIR, DSC and SEM. Keywords: glibenclamide, PEG 6000, PVP K-30, solid dispersion, factorial design

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