cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Erma Sulistyaningsih
Contact Email
sulistyaningsih.fk@unej.ac.id
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kab. jember,
Jawa timur
INDONESIA
e-Journal Pustaka Kesehatan
Published by Universitas Jember
ISSN : 2355178X     EISSN : 27213218     DOI : -
Core Subject : Health, Science,
Health Professions Library & Information Science
e-Journal “Pustaka Kesehatan” merupakan jurnal elektronik ilmiah berISSN (ISSN: 2355-178X) yang menerbitkan artikel hasil penelitian di bidang kesehatan secara umum meliputi: Kedokteran, Kedokteran Gigi, Kesehatan Masyarakat, Farmasi, dan Ilmu Keperawatan. Artikel yang dikirim belum pernah dipublikasikan atau tidak dalam proses penerbitan dalam jurnal ilmiah lain. e-Journal “Pustaka Kesehatan” diterbitkan tiga kali dalam setahun, yaitu bulan Januari, Mei, dan September.
Arjuna Subject : -
Articles 621 Documents
 29   30   31   32   33 
Optimasi Konsentrasi Hidroksipropil Selulosa dan Polivinilpirolidon dalam Sediaan Buccal Film Simvastatin (Optimization Of Hydroxypropyl Cellulose and Polyvynylpyrolidone Concentration in Simvastatin Buccal Film) Nurul Qomariyah; Lidya Ameliana; Lusia Oktora Ruma Kumala Sari
Pustaka Kesehatan Vol 5 No 1 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v5i1.3951

Abstract

Simvastatin, an antihyperlipidemia drug belongs to HMG-CoA reductase inhibitor, has extend first-pass metabolism and low bioavailability (5%) with 95-98% protein bond and short half-life (2 hours). The problem of low bioavailability can be solved by buccal delivery systems with producing simvastatin mucoadhesive buccal film. Concentration of HPC and PVP can affect the value of simvastatin release and mucoadhesive strength of film. Optimization using factorial design method determine the optimum concentration of HPC and PVP with highest simvastatin release and mucoadhesive strength. Solvent casting method used for preparation of 4 formula according to factorial design. The result was formula A (FA) with HPC and PVP concentration ratio (50: 10) gave the highest simvastatin release at 95.41% and the highest mucoadhesive strength at 73.37 grams. FTIR analysis results of FA indicated that there were no change in the functional groups on simvastatin as an active ingredient, and the mucoadhesive residence time showed that FA buccal films can be attached to the goat buccal tissues for 186 minutes. Keywords: Buccal film, mucoadhesive, simvastatin, HPC, PVP, factorial design. 
Hubungan antara Karakteristik Responden dan Sikap Kerja Duduk dengan Keluhan Nyeri Punggung Bawah (Low Back Pain) Pada Pekerja Batik Tulis (The Relationship Among Respondent Characteristic and Awkward Posture with Low Back Pain in Batik Workers) Amalia Riza Umami; Ragil Ismi Hartanti; Anita Dewi P Sujoso
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The batik worker is one of the occupational working with risk of low back pain. Low back pain is one of clinical syndrome which marked by pain as the main symptom or the pain in low back area. This research aim was to analyze the relationship among respondent characteristic and awkward posture with low back pain in batik workers at batik industry in Sumberpakem, Sumberjambe sub-district with cross sectional design. This research technique analyze use Cramer Coefficient C statistic test with α= 0,05. The results of this research showed that there are significant relations among age (0,031<0,05), length of working (0,00<0,05), nutritional status(0,03<0,05) and also awkward posture (0,001<0,05) with low back pain. Then not significant relationhip between sport habitual (0,201>0,05)with low back pain. Keywords: Respondent Characteristic, Low back pain, Batik workers, Awkward posture
Kajian Keputusan Badan Usaha terhadap Kepesertaan Jaminan Kesehatan Nasional di Kabupaten Jember (Corporations Decision on the Involvement in National Health Insurance in Jember) Galih Dwi Damaiyanti; Eri Witcahyo; Ragil Ismi Hartanti
Pustaka Kesehatan Vol 6 No 1 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i1.6769

Abstract

Abstract National Health Insurance (NHI) is a part of the National System of Social Insurance which is estabilished by Social Agencies of Health. One of the problems in NHI is corporations membership. All employers such as State-Owned Enterprise (BUMN), large, medium or small scale corporations are the target member of NHI, at least by January 1st 2015, but this target has yet to be actualized. The number of corporation in Jember, by February 2017, has reached 2451 and only 954 corporations were registered (38,92%). The objectives of this study was to assess corporations decision on NHI membership. The study applied qualitative case study. Informant determination technique uses purposive sampling. The results showed that the components of input was not appropriate. Knowledge, perception on product characteristics and need of informants were low, reference group posed significant influence on the corporations decision making in taking part in NHI. The decision making process has yet optimal in the problem or needs analysis and alternative evaluation, corporations tended to be passive in searching information. The output was membership classification of corporations in NHI has yet to be actualized. Key Words : National Health Insurance, Corporation
Uji Klinis Penggunaan Pasta Gigi Herbal Terhadap Penurunan Indeks Plak Rongga Mulut (Clinical Trial of Herbal Toothpaste to Reduce Plaque Index in Oral Cavity ) Danang Dewantara Ananda Putra; Pudji Astuti; Abdul Rochim
Pustaka Kesehatan Vol 3 No 2 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Toothpaste with a toothbrush are control hygiene and health of the oral cavity by means of cleaning plaque and food residues. Maintenance of teeth and cleaning the mouth is one of the efforts to improve health, but there are many people did not know is there a difference in cleaning the plaque herbals toothpastes. Objective: To compare plaque index pre and post given herbal toothpaste, and compare plaque index among herbal toothpaste. Methods: Research clinical trials that followed by 15 subject of study was more than 12 years old or arrangement of teeth complete permanent eruptive. Fifteen the subject divided into three groups using pre post test control group design and cross over design, the subject of brushing teeth with three different toothpaste. Result: Paired t-test result showed (p<0,05) there was significant reduction of plaque index between pre and post intervension herbal toothpaste and control toothpaste. One Way Annova test showed (p>0,05) there was no significant differences between those toothpaste to reduce plaque index. Conclusion: All of herbal toothpaste significant reduction of plaque index between pre and post intervension. There was no significant differences between those herbal toothpaste to reduce plaque index. Keywords: plaque index, herbal toothpaste
Pengaruh Ekstrak Metanol Biji Pepaya Tua dan Ekstrak Metanol Biji Pepaya Muda (Carica papaya L.) terhadap Kualitas dan Kuantitas Spermatozoa Tikus Putih Jantan (Rattus norvegicus) (Effect of Methanolic Extract of Ripe and Raw Papaya Seeds (Carica papaya Dwi Novita Wijayanti; Siti Muslichah; Endah Puspitasari
Pustaka Kesehatan Vol 4 No 3 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This research was aimed to determine the effect of antifertility among the methanol extract of ripe and raw papaya seeds in decreasing the quality and quantity of spermatozoa. Animal test rats were divided into 3 groups: negative control (CMC-Na 1%) and the treatment groups given methanol extract of ripe and raw papaya seeds extract. The extracts were given orally for 20 days. On the 21st day, mice were dissected to obtain sperm from the cauda epididymis, then were observed for the quality (motility, viability, morphology) and the quantity of spermatozoa. One-Way ANOVA followed by Post Hoc Test LSD analysis showed that was better for its activity then that of the ripe papaya seed extract. Keywords: ripe papaya seed, raw papaya seed, quality, quantity, spermatozoa
Kelayakan Buku Pop-Up Sebagai Alternatif Media Pendidikan Kesehatan Reproduksi (The Feasibility of Pop-Up Book as Alternative Reproduction Health Education Media) Rika Agustin; Erdi Istiaji; Dewi Rokhmah
Pustaka Kesehatan Vol 2 No 2 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Children are always risky exposed to pornography of mass media every day. Children sexualviolence is growing too, especially the number of case of sexual violence always ranks topthan other case of violence in Jember regency. The existence of awareness of reproductionhealth education grants in children early is one way to cope with case of sexual violence.Researcher made pop-up book as an alternative reproduction health education mediadevoted to elementary school students between grade 3-4. This research aimed to find outthe feasibility of the pop-up book media from presenting physical appearance and suitabilityof the material. This research was applied in descriptive method with qualitative approach.Data was collected by in-depth interview, triangulation, and documentations. The resultshowed that overall the colors used were in accordance with the children for colorfull,typography used have qualified legibility and readability, lllustrations used was in accordancewith the explanation was given and so attractive for children, and the layout of were used as awhole had met the principle of unity. While the content of each theme was in compliance withthe children, but there had to be improvement of the writing, the use of words, and thecontent.Keywords: Pop-Up, Reproduction Health, Children
Kadar Puncak (Cmax), Waktu Puncak (Tmax), Waktu Paruh (T½) dan Bersihan Teobromin pada Sukarelawan Sehat setelah Pemberian Dark Chocolate Bar Per Oral Nyoman Defriyana Suwandi; Cholis Abrori; Muhammad Hasan
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7620

Abstract

Dark chocolate contains two derivates of metilxantin, I.e. caffeine (1,3,7-trimetilxantin) and theobromine (3,7 dimetilxantin). Theobromine can be found in plasma. Theobromine concentration in plasma determined not only by drug dosage but also by pharmacokinetic parameters. This research aimed to determine pharmacokinetic parameters by using HPLC (High Performace Liquid Chromatography) method. This study used Quasi Experimental Design by using 16 plasma samples collected at the 0, 1.5, 3, 6, 10, 24 hours. The pharmacokinetic parameter calculations were obtained from the polynomial curve and linear curve of drug concentration in plasma by time. The maximum concentration (Cmax) theobromine on plasma after consumption of dark chocolate bar per oral was 4.173 mg/L. The maximum time (Tmax) was at the 2.501 hours. The half time (t½) theobromine was 4.880 hours. Theobromine clearance in plasma was 14.2 ml/kg/hour. The study has reported pharmacokinetic parameters of theobromine in plasma after eating dark chocolate bars orally. Keywords: Chocolate, half-time, maximum concentration, maximum time, theobromine
Upaya Promosi Kesehatan Pendewasaan Usia Perkawinan Oleh Pusat Informasi Konseling Remaja (PIK-R) Ditinjau Dari Teori Precede-Proceed (The Effort of Health Promotion on Maturation of the Marriage Age by Information and Concelling Center for Adolescent (PI Dina Mei Wahyuningrum; Husni Abdul Gani; Mury Ririanty
Pustaka Kesehatan Vol 3 No 1 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The result of UNICEF report showed that Indonesia has high percentage on early marriage inthe world, Indonesia was in 37th rank from 63 country. One of district in Jember regency whichhas the highest mark in early marriage is Sukowono district. There were 411 mate whomarriage in early age. The effort to reduce the amount of early marriage was by maturation ofthe age marriage which hold by information and conselling center for adolescent (PIK-R). Theactivity of PIK-R in effort on Maturation of marriage age by giving information, but this activityonly give to the members of PIK-R. It caused most of adolescent didn't know more aboutmaturation of marriage age. The purpose of this research was to know effort of healthpromotion on maturation of the marriage age by PIK-R based precede proceed theory. Thisresearch design used Qualitative research based on the result showed that most of society inSukowono district did early marriage because their parents were match them, so their familygave support to do early marriage. The effort of maturationof the marriage age which washold by PIK-R consist of planning, implementation and evaluation. Planning of PIK-R consistof target determined, content, media, advocacy and regulacy. The implementation of PIK-Rwas hold by giving information to the society about maturation of the marriage age, butevaluation from implementation was not suitable with planning.Keywords : Health promotion on maturation of the age marriage, PIK-R, Precedeproceedtheory.
Pengaruh Ekstrak Metanol, Fraksi N-Heksana, dan Fraksi Metanol Biji Pepaya (Carica papaya L.) terhadap Kadar Testosteron dan Bobot Organ Reproduksi Tikus Jantan (Effect of Methanolic Extract, N-Hexanic Fraction, and Methanolic Fraction of Papaya Seed (Ca Dwi Puspita Sari; Siti Muslichah; Wiratmo Wiratmo
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Papaya seeds (Carica papaya L.) was known have antifertility activity. Testosterone hormone and reproduction organs weight are influence antifertility activity. This study was conducted to compare the effect of the methanolic extract, fraction of n-hexane, and fraction of methanol papaya seeds ( dose 100 mg/kg BW ) with testosterone level and reproduction organs weight parameters of male rats. Measurement of testosterone level by ELISA method. The observation found that the three treatment didn’t decrease reproduction organs weight but decrease testosterone level compared to negative control group. Among the three treatments, metyhanolic extract and methanolic fraction decreased testosterone level. Extract and fraction of methanol alleged alkaloid content of which is known to inhibit development and count of spermatogenic cell.   Keywords: papaya seeds, testosterone, alkaloid, organ
Efek Penambahan Vitamin C terhadap Aktivitas Klindamisin dalam Menghambat Pertumbuhan Streptococcus pneumoniae secara In Vitro Bagus Dwi Kurniawan; Dini Agustina; Erfan Efendi
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.9744

Abstract

Pneumonia is one of the lower respiratory tract infection involving respiratory bronchioles and alveoli that mostly caused by Streptococcus pneumoniae.Clindamycin is one of the drug of choice for pneumoniae. This drugs inhibits the growth of S. pneumoniae by producing ROS (Reactive Oxygen Species). Recent study has shown that vitamin C could generate ROS leading to DNA-damage on bacteria. The aims of this study was to know the possible benefit effect of adding vitamin C towards clindamycin inhibition activity against the growth of S. pneumoniae in vitro. This research was conducted by using 7 groups which consist of negative control (aquades), positive control (clindamycin), and test group 1 until 5 that given the combination of clindamycin and vitamin C as follows 2,5 mg/ml; 5 mg/ml; 10 mg/ml; 20 mg/ml; and 40 mg/ml. The inhibition effect of growing S. pneumoniae shown by the inhibition zone diameter. The average of inhibition zone on negative control, positive control, and test group were 5; 24,12; 24,62; 26,08; 27,58; 28,74; and 29,76 mm. These result show a significant correlation based on Pearson test (the coefficient correlation’s result is +0,910). The logarithmic regression revealed the minimal concentration of vitamin C was 1,767 mg/ml. It can be concluded that vitamin C increased the activity of clindamycin by inhibiting the growth of S.pneumoniae in vitro. Keywords: Streptococcus pneumoniae, ROS, Clindamycin, Vitamin C

Page 31 of 63 | Total Record : 621

 29   30   31   32   33 

Filter by Year

2013 2025


Reset
Filter By Issues
All Issue Vol. 13 No. 1 (2025): Volume 13 No. 1, 2025 Vol. 12 No. 3 (2024): Volume 12 No. 3, 2024 Vol 12 No 2 (2024): Volume 10 No.2, 2024 Vol 12 No 1 (2024): Volume 12 No.1, 2024 Vol 11 No 3 (2023): Volume 11 No.3, 2023 Vol 11 No 2 (2023): Volume 11 No.2, 2023 Vol 11 No 1 (2023): Volume 11 No.1, 2023 Vol 10 No 3 (2022): Volume 10 No.3, 2022 Vol 10 No 2 (2022): Volume 10 No.2, 2022 Vol 10 No 1 (2022): Volume 10 No.1, 2022 Vol 9 No 3 (2021): Volume 9 No.3, 2021 Vol 9 No 2 (2021): Volume 9 No.2, 2021 Vol 9 No 1 (2021): Volume 9 No.1, 2021 Vol 8 No 3 (2020): Volume 8 No. 3, 2020 Vol 8 No 2 (2020): Volume 8 No. 2, 2020 Vol 8 No 1 (2020): Volume 8 No. 1, 2020 Vol 7 No 3 (2019): Volume 7 No.3, 2019 Vol 7 No 2 (2019): Volume 7 No. 2, 2019 Vol 7 No 1 (2019): Volume 7 No. 1, 2019 Vol 6 No 3 (2018) Vol 6 No 2 (2018) Vol 6 No 1 (2018) Vol 5 No 3 (2017) Vol 5 No 2 (2017) Vol 5 No 1 (2017) Vol 4 No 3 (2016) Vol 4 No 2 (2016) Vol 4 No 1 (2016) Vol 3 No 3 (2015) Vol 3 No 2 (2015) Vol 3 No 1 (2015) Vol 2 No 3 (2014) Vol 2 No 2 (2014) Vol 2 No 1 (2014) Vol 1 No 1 (2013) More Issue