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INDONESIA
e-Journal Pustaka Kesehatan
Published by Universitas Jember
ISSN : 2355178X     EISSN : 27213218     DOI : -
Core Subject : Health, Science,
e-Journal “Pustaka Kesehatan” merupakan jurnal elektronik ilmiah berISSN (ISSN: 2355-178X) yang menerbitkan artikel hasil penelitian di bidang kesehatan secara umum meliputi: Kedokteran, Kedokteran Gigi, Kesehatan Masyarakat, Farmasi, dan Ilmu Keperawatan. Artikel yang dikirim belum pernah dipublikasikan atau tidak dalam proses penerbitan dalam jurnal ilmiah lain. e-Journal “Pustaka Kesehatan” diterbitkan tiga kali dalam setahun, yaitu bulan Januari, Mei, dan September.
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Articles 621 Documents
Sintesis Asam 2-(2-(n-(2,6-diklorofenil)-4 fluorobenzamida)fenil)asetat sebagai Kandidat Obat Penghambat COX (siklooksigenase) Triodora Hutahuruk; Ayik Rosita; Ika Oktavianawati
Pustaka Kesehatan Vol 2 No 2 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Sodium diclofenac is a non selectif NSAID that used as an inflammatory, analgesic, and antipyretic. Several experiment about compound as a derivate sodium diclofenac has been synthesized for reduce side effect. 2-(2-(N-(2,6-dichlorophenyl)-4-fluorobenzamido)phenil)acetat acid (N4FND) is derivate of sodium diclofenac that synthesized for development of drugs. The target compound has been synthesized by benzoylation reaction between sodium diclofenac with 4-fluorobenzoylchloride. And then, the target compound has been purified using Coloumn Chromatography. The isolate was identified using 1HNMR 400 MHz and KBr FTIR. Spectra of of 1HNM 00 MHz and KBr FTIR showed that 2-(2-(N-(2,6-dichlorophenyl)-4-fluorobenzamido)phenil)acetat acid was successfully synthesized. Pure product compound form yellowish white crystals with melting point 165-1670C.
Hubungan antara Tingkat Pengetahuan Pasien dan Pengawas Menelan Obat (PMO) dengan Kepatuhan Pasien Tuberkulosis di Puskesmas Kabupaten Jember Antonius Nugraha Widhi Pratama; Amelya Prastica Rahayu Aliong; Nili Sufianti; Ema Rachmawati
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7570

Abstract

Tuberculosis (TB) is an infectious disease that mostly affects developing countries. In Indonesia, TB incidence increases every year due to patient inadherence to the standard DOTS therapy. The TB patients inadherence can be associated with poor knowledge among patients and treatment observers. This cross-sectional research aimed to explore the correlation between knowledge level of TB patients and their treatment observers and patient adherence. Purposive sampling technique was used to collect data from 65 respondents from their primary health centers in Jember Regency, East Java. Knowledge of the respondents was evaluated using a 16 items questionnaire and patient adherence was assesed using the translated version of morisky medication adherence scale-8 (MMAS-8) questionnaire. The Spearman Rho correlation test resulted in p value of 0,043 between patients knowledge and patients adherence. Statistically significant correlation was also found between the knowledge of treatment observers and TB patients adherence (p= 0,015). These results suggested the needs to improve knowledge about TB not only for TB patients, but also their treatment observers. Keywords: TB patient, treatment observer, knowledge, compliance
Peran dan Fungsi Kader, Dukungan Sosial Suami, dan Pengetahuan Tentang Budaya Keluarga pada Pelaksanaan Keluarga Sadar Gizi (Roles and Functions of Cadre, Husband Social Support, and Knowledge of Family Culture on the Implementation of Nutrition Conscious Ika Murni Saputri; Sulistiyani Sulistiyani; Ninna Rohmawati
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Family that is aware of nutrients is family that all members having good nutrition behavior. Pesanggaran was first place in Banyuwangi which has the lowest of implementation nutrition conscious family, it was 43,3%. The purpose of this study was to analyze the correlation between roles and functions of cadre, husband social support, and knowledge of family culture with the implementation of nutrition conscious family which was held July-August 2015 and used cross sectional approach. The research sample consists of 80 families. The result showed implementation of nutrition conscious family in region of Pesanggaran Public Health Centre was 35%. Based on bivariate analysis, it was found that roles and functions of cadre in the increasing in maternal health, baby, toddler, and socialization Kadarzi, husband social support (emotional, award, instrumental, infoemative), and knowledge of family culture had a significant relationship with the impleentation of Knutrition conscious family.The role and function of cadre in a socialization Kadarzi was the most dominant factor related to implementation of Knutrition conscious family on the family of toddler. Keywords: Kadarzi, toddler, risk factor
Efek Analgesik Kombinasi Kurkumin dan Parasetamol pada Mencit yang Diinduksi Asam Asetat menggunakan Isobologram (The Analgesic Effect of Combination of Curcumin and Paracetamol in Acetic acid-induced Mice using Isobolograms) Nugroho Priyo Utomo; Cicih Komariah; Yudha Nurdian
Pustaka Kesehatan Vol 5 No 2 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Paracetamol is a drug that classified as NSAID and commonly used as analgesic agent. These drugs have toxic effects that lead to liver damage. This effects caused by accumulation the metabolite compound of paracetamol, N-acetyl-p-benzoquinone (NAPQI), by cytochrome P450 enzyme. Some studies reported that curcumin have analgesic effects and inhibit action of cytochrome P450 enzyme. The purpose of this study was to determine the analgesic effect of curcumin and paracetamol combination in 27 acetic-acid induced mice. The result of this study showed that 2358,815 µg of curcumin and paracetamol combination can inhibit pain up to 50%. This result is smaller than paracetamol that need 4200 µg to achieve the same pain inhibition. One Way Annova test showed siginificant difference between paracetamol group and combination group. Isobolographic analysis results showed curcumin and paracetamol have synergistic properties in mice acetic-acid induced pain. Keywords: curcumin, paracetamol, isobolograph
Pengaruh Pijat Bayi Terhadap Bounding Attachment di Ruang Dahlia RSD dr. Soebandi Jember Sri Wahyuni; Dini Kurniawati; Hanny Rasni
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7782

Abstract

Bounding attachment is very important for newborn to be adapted to the new environment. Mother’stouch can help babies adapt to environmental differences between inside the womb and outside thewomb. How to improve the bounding attachment is early breastfeeding initiation, rooming in,kangaroo mother care for premature, and baby massage. The purpose of this research is todetermine the impact of baby massage to bounding attachment. The method of research was quasiexperimental with design of research pretest-post test with control group. This research is in Dahliaroom in dr. Soebandi general Hospital, with samples as 40 respondent with 20 people forexperimental group and 20 people for control group. The research use standard operationalprocedure of baby massage and quality of bounding attachment questionnaire. Take the sample bypurposive sampling. The results of research is give difference in average pretest-post test on theexperimental group of -7,35 whereas on the control group of -2,55. Statistic test result obtained the pvalue 0.001, this mean on the alpha 5% can be expressed there is influence of baby massage forbounding attachment. There are several factors that influence to the bounding attachment that isemotional health of parent, family support, the proximity and match of the parents and baby. Theresult of this research are recommended as the nursing treatment and to the public especiallymother postpartum.Keywords : baby massage, bounding attachment
Pengaruh Pemberian Ekstrak Etanol Brokoli (Brassica oleracea) terhadap Kadar SGOT dan SGPT Tikus Wistar yang Diinduksi DMBA (The Effect of Ethanolic Extract of Broccoli (Brassica oleracea) on SGOT and SGPT of Wistar Rats Induced by DMBA) Rizka Nuzula Wardani; Elly Nurus Sakinah; Yudha Nurdian
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

DMBA is a product of incomplete burning which can cause free radicals in human. The metabolism of DMBA by Cytochrome P450 in liver causes hepatocyte DNA damage and decrease endogenous antioxidant. Broccoli contains flavonoid which can act as an antioxidant by inhibiting formation of free radicals through hydrogen atom donation to free radicals. This research aimed to analyze the effect of ethanolic extract of broccoli on SGOT and SGPT of wistar rats induced by DMBA. This research used 24 rats divided into six groups: control group, negative control group, and four treatment groups with broccoli ethanolic extract of 250 mg/kgBW, 500 mg/kgBW, 1000 mg/kgBW, and 2000 mg/kgBW for 7 days. The SGOT and SGPT levels of control group were 70,36 U/L and 33,97 U/L; negative control group 107,16 U/L and 56,21 U/L; the first treatment 101,50 U/L and 49,33 U/L; the second treatment 85,32 U/L and 43,67 U/L; the third treatment 84,11 U/L and 40,84 U/L; and the fourth treatment 81,28 U/L and 35,18 U/L. The result of One Way Annova test for SGOT was p=0,012 while SGPT was p=0,003. In this study, ethanolic extract of broccoli could protect hepatocyte by decreasing SGOT and SGPT levels.   Keywords: ethanolic extract of broccoli, SGOT and SGPT levels, DMBA
Pengembangan Bromfenol Biru dan Bromtimol Biru pada Label Pintar Sensor Kematangan Buah Naga Merah (Hylocereus polyrhizus) (The Development of Bromophenol Blue and Bromothymol Blue on Ripeness Sensor Smart Label on Red Dragon Fruit (Hylocereus polyrhizu Raden Ayu Rifqa Zainatul Hurriyah; Bambang Kuswandi; Dwi Koko Pratoko
Pustaka Kesehatan Vol 5 No 3 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v5i3.5890

Abstract

The novel on-package color indicator label has been fabricated based on bromophenol blue and mixture between bromophenol blue and bromothymol blue, and tests have been conducted to assess the ripeness of red dragon fruit (Hylocereus polyrhizus). Bromophenol blue (BPB) and mixture between bromophenol blue and bromothymol blue (BTB) were immobilized onto acetate cellulose membrane via adsorption method. The BPB and mixture between BPB and BTB/acetate cellulose membrane as color indicator work based on pH decrease as the volatile organic compounds (e.g. acetic acid). They produced gradually in the package headspace during developing of red dragon fruit. Subsequently, the color of the indicator will change from blue to green for over-ripe indication, which can be visible visually. The results showed that the color indicator could be used to determine the state of ripeness of the red dragon at ambient condition (25±2oC) and chiller condition (4±2oC). The color change of the indicators reflects the pH of headspace of the red dragon packaging. Furthermore, it also in similar trends to the change of several parameters (soluble solids content, pH, texture, sensory evaluation and weight loss) that normally used to characterize the ripeness of red dragon, therefore the indicator can be used for real time visual monitoring of ripeness state of packaged red dragon fruit. Keywords: ripeness indicator, BPB, BTB, red dragon fruit, acetate cellulose membrane
Efek Ekstrak Etanol Biji Kakao (Theobroma cacao) sebagai Antibakteri terhadap Pseudomonas aeruginosa secara In Vitro (The Effect of Ethanolic Extract of Cocoa Beans (Theobroma cacao) as an Antibacterial against Pseudomonas Devi Chintya Kumalasari; Enny Suswati; Misnawi Misnawi
Pustaka Kesehatan Vol 3 No 1 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Nosocomial infection is one of the most serious healthy problem in the world. It causes by Pseudomonas aeruginosa which has a high resistance to antibiotic. One alternative to overcome this problem is the utilization of chocolate (Theobroma cacao) because it contains polifenol that can be used as an antibacterial agent. The aim of this research was to determine antibacterial effect and Minimum Inhibitory Concentration (MIC) of ethanolic extract of cocoa beans to P. aeruginosa by in vitro method. Antibacterial activity test used disk diffusion (Kirby Bauer) method. This type of research was a quasi-experimental with posttest only control group design. Samples used was colony of P. aeruginosa. Concentrations of test solution used were 7,81; 15,62; 31,25; 62,50; 125; 250; 500; and 1000 mg / ml. Positive control used cefepime suspension and negative control used sterile distilled water. The result showed that inhibition zones formed at a concentration of 7,81 mg/ml to 1000 mg/ml. The higher the concentration of the cocoa beans extract, the wider the inhibition zones formed. By direct measurement, MIC was obtained at the dose of 7.81 mg / ml while statistical analysis yielded an MIC value of more than 6.95 mg / ml. In conclusion, the ethanolic extract of cocoa beans had antibacterial effect on P. aeruginosa in vitro.   Keywords: antibacterial effect, cocoa beans, Pseudomonas aeruginosa
Pengaruh Pemberian Natrium Bikarbonat terhadap Kelelahan dan Nyeri Otot setelah Melakukan Treadmill Fath Arina Fahma; Cholis Abrori; Hairrudin Hairrudin
Pustaka Kesehatan Vol 7 No 1 (2019): Volume 7 No. 1, 2019
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v7i1.17590

Abstract

Treadmill is a physical exercise that caused a metabolic transition from aerobic into anaerobic. The aim of this study was to determine the effect of sodium bicarbonate to reduce fatigue and muscle pain after treadmill. This study used a time-series design with 20 selected samples from undergraduate student population of the Faculty of Medicine, Jember University. Samples consumed 100mg/kgBW NaCl (placebo) and NaHCO3 300mg/kgBW then perform a treadmil protocol until it reached maximum muscle fatigue. The results showed that the average treadmill of the treatment group (778,1±121,21 seconds) was longer than control group (717,7±93,02 seconds). The intensity of acute pain as measured by VAS (Visual Analog Scale) treatment group was lower (44,7±22,47 units) than control (55,4±19,97 units). So this study inferred that NaHCO3 can reduce fatigue and acute pain intensity after treadmill.
Motivasi Perawat dalam Pemenuhan Kebutuhan Spiritual pada Klien di Ruang Rawat Inap Rumah Sakit Daerah Balung (Nurses Motivation to Patients Spiritual Needs Fulfillment at Balung Hospital) Ahmat Robbi Tricahyono; Retno Purwandari; Mulia Hakam
Pustaka Kesehatan Vol 3 No 3 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Nursing care is done by considering individuals as the holistic (bio-psycho-socio-spiritual) creature, particularly in fulfilling spiritual needs. This research was intended to analyze the relationship between the nurses motivation and patients spiritual needs fulfillment at Balung Hospital. This research applied observational analytic method with cross sectional. Sampling technique used total sampling by involving 48 respondents. Data was analyzed using nonparametric Chi Square. The result of the analysis reveal that the majority of the motivation of the nurses was influenced by extrinsic motivation, 72,7% of high motivation and good spiritual fulfillment, 38,5% of low motivation was good spiritual fulfillment, 61,5% of low motivation was bad spiritual fulfillment, and 27,3% of high motivation was bad spiritual fulfillment. Results of statistical analysis showed that the p-value is 0,037 (α=0,05) which indicates the relationship between nurses motivation and spiritual needs fulfillment to patients at Balung Hospital. Fulfilling spiritual needs is an important aspect in the process of treating the clients. It is the nurse’s duties to observe then fulfill the patients spiritual needs. Hence, coordination with other medical team through various discussions is an immediate importance. Nurses are expected to meet the patients needs of spiritual aspects in order to achieve a more holistic nursing care.   Keywords: nursing care, motivation, spiritual fulfillment