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Althea Medical Journal
ISSN : -     EISSN : 23374330     DOI : 10.15850/amj
Core Subject : Health,
Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and public health.
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Articles 1,078 Documents
The Effect of Breadfruit Leaves Infusion on Acute Renal Failure Rat model Abstract Hardani, Muhamad Risdan; Sastramihardja, Herri S.; Afiatin, Afiatin
Althea Medical Journal Vol 2, No 4 (2015)
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Abstract

Background : Empirically, breadfruit (Artocarpus altilis) leaf has been used as traditional medicine for several diseases, such as acute renal failure. This research is aimed at finding the effects of breadfruit leaf infusion on blood creatinine levels in rats to model acute renal failure.Methods : This research is an experimental study, using 30 male wistar rats, weighing 150–250 g, divided into 5 groups. The first group is a negative control and the second group is a positive control. Groups 2–5 were induced with Gentamicine and peroxicam for 7 days, and then groups 3–5 given infusion of breadfruit leaf in different doses for 7 days, and then blood creatinine levels were tested at the 15th day. This data was analyzed using a multiple comparison Dunnett T3 test because this data is not homogenous. This research was done in pharmacology laboratorium universitas padjadjaran from Oktober–November 2012.Result : Bases on average creatinine levels of 0.62, 0.87, 0.98, and 0.87 mg/dL observed for the diffetent groups, it was statistically show that significantly different creatinine levels, differing by 0.038 (p < 0.05) were observed for the control group and the group which was given an infusion of breadfruit leaf.Conclusion : It can be concluded that infusions of breadfruit leaf do have an effects on blood creatinine levels in acute renal failure.Key words : acute renal failure, breadfruit leaf, creatinine  DOI: 10.15850/amj.v2n4.527
Characteristics of Patients with Estrogen Receptor (ER)-Negative, Progesterone Receptor (PR)-Negative, and HER2-Negative Invasive Breast Cancer in Dr. Hasan Sadikin General Hospital, Bandung, Indonesia from 2010 to 2011 Kusumadjayanti, Nadytia; Badudu, Dharmayanti Francisca; Hernowo, Bethy S.
Althea Medical Journal Vol 2, No 3 (2015)
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Abstract

Background: Breast cancer is the most common type of cancer that has been diagnosed among Indonesian women. One of the subtypes that frequently being studied is the triple negative breast cancer which has poorer prognosis among all subtypes. The objective of this study was to investigate the incidents and the characteristics of triple negative breast cancer patients.Methods: This study used triple negative breast cancer patients’ medical records in Dr. Hasan Sadikin General Hospital. Some characteristics were identified, such as age at presentation, menopause status, tumor size, stage at presentation, grades of tumor, pathological features, and metastatic status.  Data were taken during 2010 and 2011 and presented in table.Results: Thirty women among 252 patients were identified as having triple negative breast cancer. Based on those 30 cases, 11 patients were in the age group of 40‒55 years. Fifteen out of 30 cases were premenopausal. From 30 cases, 14 patients had tumor size bigger than 5 cm.  Sixteen cases had stage III tumor.  Most of the cases were invasive ductal carcinoma mammae as their histological features. Two cases had metastized to pleura.Conclusions: The incidence rate of triple negative breast cancer in Dr. Hasan Sadikin General Hospital is 11.9% with these common characteristics: range of age are between 40 to 45 years, have a premenopausal, had >5cm tumor , stage III tumor and has histological feature IDC, and only 2 patients were metastized to pleura. DOI: 10.15850/amj.v2n3.494
Relationship between Exclusive Breastfeeding and Nutritional Status of Infants Aged 12 months Selvina, Sheilla; Fadlyana, Eddy; Arisanti, Nita
Althea Medical Journal Vol 2, No 4 (2015)
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Abstract

Background: Exclusive breastfeeding has a high nutrient content to fulfill the nutritional needs of infants aged 0−6 months. The aim of this study was to describe thenutritional status of infants aged 12 months and to determine the relationship of exclusive breastfeeding and nutritional status of infants aged 12 months in Pos Pelayanan Terpadu (Posyandu) Cipacing Village Jatinangor.Methods: A cross sectional study was carried out to 102 mothers with infants aged 12 months in Posyandu Cipacing Village from September to October 2013. The infants’ body weight were weighed with weight scales which had been calibrated and the body length were measured with the Seca 210 baby length measuring mat, then the mother was interviewed with a questionnaire which had been validated to inquire about the exclusive breastfeeding history. The Fisher exact test was used to assess relationship between both variables.Results: There were 81.3% of infants with good nutritional status and 83.3% of infants who did not get exclusive breastfeeding. The analysis test showed that the p-value of relationship between exclusive breastfeeding and nutritional status was 0.458 with odds ratio 3.343.Conclusions: Most of the infants are in good nutritional status although they do not get exclusive breastfeeding. Consequently, there is not a significant relationship between exclusive breastfeeding and nutritional status. [AMJ.2015;2(4):534–40] DOI: 10.15850/amj.v2n4.638
Characteristic and Knowledge among Treatment Supporter of Children Patients with Tuberculosis at Lung Clinic Bandung October–November 2012 Suhada, Kamelia Utami; Sari, Sri Yusnita Irda; Wulandari, Diah Asri; Setiawati, Elsa Pudji
Althea Medical Journal Vol 2, No 2 (2015)
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Abstract

Background: Children are the most vulnerable to get TB infection and infected by adult patients. One of the components of Directly Observed Treatment Short Course (DOTS) is direct observation by treatment supporter who has important role in the success of TB’s treatment. The aim of this study was to identify the characteristics and knowledge among treatment supporter of children patients with TB at Lung Clinic Bandung.Methods: A descriptive study was conducted in October-November 2012 to 96 treatment supporters of child patients who were diagnosed with TB, either new or old cases. They were selected by consecutive sampling at Lung Clinic Bandung. Validated questionnaire with 14 questions was administered. The percentage of the correct answers was categorized as good, moderate, and poor. The Characteristic variables included age, sex, education, occupation, relation with the patients, living at the same house, presence of other TB patients, and counseling given by providers. Data was analyzed using frequency distribution.Result: Most of the respondents were 21-30 years old (42.7%), female (84.4%), elementary school graduate (33.3%), unemployed (69.8 %), mother of the child, living in the same house, had other TB patients, and had received counseling by providers at Lung Clinic. The knowledge about TB among the respondents was moderate (56.3%). The respondents who had good knowledge had underwent the counseling session.Conclusions: The knowledge of the respondents was moderate. Further study on the relationship between the level of knowledge of treatment supporter and the adherence of TB treatment should be conducted. [AMJ.2015;2(1):167–71]
Factors Related to the Intention to Cigarette Smoking among Junior High School Students in Jatinangor Subdistrict, West Java Yee, Ngu Ling; Sunjaya, Deni Kurniadi; Karyono, RM Haryadi
Althea Medical Journal Vol 2, No 3 (2015)
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Abstract

Background: Cigarette smoking is known to harm the health of smokers and causes the death of millions people around the world. Smoking initiation in Indonesia is begun early especially during teenagers year. The aim of the study was to analyze the factors related to the intention to cigarette smoking among Junior High School students in Jatinangor subdistrict.Methods: A quantitative method with cross sectional study was conducted in the junior high school setting during the period of September to November 2013. Inclusion criterias were students aged 13­15 years old and did not smoke. Four factors were measured in this study, which were attitudes toward cigarette smoking, parents who smoke, peers influence and advertisement where each factor had 5 questions with ‘Yes’ or ‘No’ answers. Data were collected through self-administered questionnaire among 226 students using stratified random sampling. Statistical analysis of the variables was using chi square test.Results: As much as 44.25% of the respondents had intention and 55.75% had no intention to cigarette smoking. This study showed significant relation among attitudes, parents who smoke, peers influence and advertisements with the intention to cigarette smoking.Conclusions: Half of the respondents have intention to cigarette smoking and the most factors related to it are peers influence. DOI: 10.15850/amj.v2n3.528
Correlation between Six-Minutes’ Walk Test and Quality of Life in Heart Failure Patients Erwinanto, Erwinanto; Andean, Rudolf; Rahmani, Syifa
Althea Medical Journal Vol 2, No 4 (2015)
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Abstract

Background: The problem of heart failure patient relates with reduced functional capacity and eventually leads to declined quality of life (QoL). Improved QoL may not relate to better functional capacity since QoL is influenced by patient’s expectation to the on-going treatment. This study was conducted to investigate the correlation between  six-minutes’ walk test (6MWT) as a measure for functional capacity and QoL of heart failure patient in Dr. Hasan Sadikin General Hospital.Methods: This cross sectional study involved 32 patients who were on planned visit at the outpatient clinic of Dr. Hasan Sadikin General Hospital Bandung from September to October 2013. Subjects were chosen using consecutive sampling. The correlation of 6MWT and QoL assessed using modified Minnesota Living and Heart Failure Questionnaire (MLHFQ) was analyzed through Pearson’s correlation test.Results: There was a significant correlation between distance covered in 6MWT and QoL (r=-0.354, p<0.05).The mean of six-minute walk distance was 277.96 (±42.17) and mean of QoL score was 33.41 (±7.88). In accordance with the findings in previous studies, this study revealed correlation between the distance obtained in 6MWT and the QoL score in heart failure patient.Conclusions: There is correlation between 6MWT and quality of life in outpatients with heart failure at Dr. Hasan Sadikin General Hospital. [AMJ.2015;2(4):469–73] DOI: 10.15850/amj.v2n4.629
Effect of Neem Leaves Extract (Azadirachta Indica) on Wound Healing Rubianti, Irra; Chundran, Naveen Kumar; Husen, Ike Rostikawati
Althea Medical Journal Vol 2, No 2 (2015)
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Abstract

Background: Neem leaves (Azadirachta Indica) have active ingredients such as nimbidin and sodium nimbidate which possess/possesinganti-inflammatory, antibacterial, antifungal and antiviral properties that help in healing process and also contains an excellent nutrition which plays/playing a vital role information of collagen and formation of new capillaries. The aim of this experimental study is to evaluate healing activity of neem leaves.Methods: This experiment was conducted in Pharmacology Lab of Universitas Padjadjaran on October 2012. Twenty seven rats were grouped randomly into 3 groups and 1.5cm of excision wound was created. Negative control group was treated with a topical application of saline solution (sodium chloride0.9%), treatment group with a topical application of neem leaves extract and positive control group had been treated with a topical application of povidone-iodine for 15 days. Healing was assessed by the longest diameter of the raw surface of wound on days 0, 5, 10 and 15. The data were then analyzed using Mann-Whitney U test.Results: There was a significant reduction in the longest diameter of wound in group of neem leaves extract, compared with group sodium chloride 0.9%,.and there was no significant difference in the longest diameter of wound between neem leaves, extract and povidone iodine. Conclusions: Neem leaves extract has the same wound healing rate compared to povidone iodine. A further study in human should be conducted in the future. [AMJ.2015;2(1):199–207]
The Role of Socioeconomic Factors Contributed to The Prevalence of Children under Five Years Old with Small Stature in Jatinangor Indari, Anggie; Setiawati, Elsa Pudji; Tarigan, Rodman
Althea Medical Journal Vol 2, No 2 (2015)
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Abstract

Background: Indonesia  is on the fifth in world population for children with small stature. It could affect to their future, so growth disorders should be detected as early as possible. The influence of growth disorders is inseparable from the socioeconomic condition of the family.  This study aims to analyze the influence of socioeconomic based on education, occupation and family income towards small stature children under five years old in Jatinangor.Methods: This was a study of analytic cross sectional with multi-stage proportionate consecutive sampling. 110 samples of children under five years of age (12–59months) from 12 villages (6087 children) in Jatinangor sub district were taken on October and November 2012. Their height was measured using a microtoise based on WHO Growth Chart and the socioeconomic status was measured using questionnaire completed by their motherResults: There were 32 children (29,1%) with small stature. The relationship between maternal education with short stature (p=0.310), father’s education with small stature (p=0.368), mother’s occupation with small stature (p=0.774), father’s occupation with small stature (p=0.524) and family income with small stature (p=0.890) after it was examined using chi-squre test were not significant (p>0.05).Conclusion: In Jatinangor, there are still many children with small stature under five years old and the socioeconomic factors do not have any relationship with this condition. [AMJ.2015;2(1):298–303]
Women’s Opinion about Women’s Rights regarding Family Planning in Hegarmanah Village, Jatinangor Subdistrict, West Java in 2013 Saw, Suzanne; Syukriani, Yoni; Kartamihardja, A. Hussein S. Kartamihardja
Althea Medical Journal Vol 2, No 3 (2015)
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Abstract

Background: Universal Declaration of Human Rights stated that all mankind have equal right and dignity. Both woman and man have rights regarding family planning. It is often assumed that in developing country, women do not consider their rights in family planning decision making process. This study was carried out to determine the opinion of women regarding women’s rights in family planning.Methods: A descriptive study was carried out to 99 respondents during the period of August to October 2013, in Hegarmanah village, Jatinangor subdistrict. The inclusion criteria were women aged 15–49 years old, able to speak Bahasa Indonesia, and agreed to participate. Variables for this study were the opinions of the respondents regarding woman’s rights in family planning which were represented in 12 questions. Collected data were presented as percentages shown in tables.Results: Most of the respondents stated that they had the rights in family planning decision making, including choosing contraceptive methods, number of children, and spacing of each child. However, all of  the respondents agreed that men should be involved in it. More than half of the respondents stated that they asked opinion from family member regarding family planning especially their mothers. Cultural norms did not influence the family planning decision making. However, religion influenced the family planning decision making.Conclusions: Majority of the women in Hegarmanah village have the role to make decision on family planning by considering the opinions of their spouses, other family members, friends and their religions. DOI: 10.15850/amj.v2n3.526
Knowledge and Attitude of Senior High School Students in Jatinangor towards Sexually Transmitted Infections in 2013 Hendrana, Aisyah Riseta Aini; Mutyara, Kuswandewi; Rowawi, Rasmia
Althea Medical Journal Vol 2, No 4 (2015)
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Abstract

Background: Sexually transmitted infections (STIs) are major health problem. Until today, the prevalence of STIs is still high and the incidence is increasing. Almost half of STIs new cases occur in adolescents andyoung adults. It is assumed that there is a positive correlation of knowledge about STIs with attitude and practices; therefore, giving proper information of STIs to adolescents could influence their safe sexual practices, and further, it can prevent STIs to occur. The objective of this study is to discover knowledge and attitude of senior high school students in Jatinangor towards STIs.Methods: This descriptive study was conducted in Sekolah Menengah Atas Persatuan Guru Republik Indonesia (SMA PGRI) Jatinangor and Sekolah Menengah Atas Negeri (SMAN) Jatinangor from May to September 2013. Questionnaires were completed by 278 respondents selected by stratified cluster random sampling.Results: More than half respondents had poor knowledge about STIs (56.5%) while 53.2% of the respondents had positive attitude towards STIs. Most mentioned choices as the information source of STIs were teacher(66.5%), followed by television/radio (45.3%), friends (37.8%), newspaper/magazine (21.2%), mother (16.2%), sibling (7.2%), and father (6.5%). Conclusions: More detail information about STIs is needed by adolescents as a way to encourage safe sexual practices. Teacher and parents are expected to be the source information of STIs while mass media can alsobe used to educate adolescents. Education on STIs for teachers is also needed since they are as the main source for educating the adolescents. [AMJ.2015;2(4):568–74] DOI: 10.15850/amj.v2n4.655

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