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HISTOPATOLOGI ARTERI KORONARIA Rattus novergicus STRAIN WISTAR JANTAN SETELAH PEMBERIAN DIET ATEROGENIK SELAMA 5 MINGGU Annisa Ul Hasanah; Enikarmila Asni; Zulkifli Malik
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 1 (2015): Wisuda Februari 2015
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ABSTRACTAtherosclerosis is a complex chronic disease characterized by the accumulation of lipid, trombosits, neutrophils, monocytes, and macrophages within arterial walls. Atherosclerosis could be induced in animal model ( Rattus novergicus ) by feeding atherogenic diet. The goal of this research was to analyze histopathological of coronary artery on male Rattus novergicus strain wistar after fed atherogenic diet for 5 weeks. This research was an experimental laboratory research with post test only with control design. Twelve male rats were segregated into two groups ( n=6 ) labelled as control fed standart and atherogenic group fed atherogenic diet containing cholic acid 0,2%, fat 5%, egg yolk 2% and induction with vitamin D3. After 5 weeks coronary artery was taken and histological slides were made and colored with Hematoxylin Eosin. The measured parameter were atherosclerosis lession score. The result showed 66% sampels that given standart diet and 100% sampels that given atherogenic diet showed atherosclerosis lession.The statistical test result showed there is no significant difference between control group and atherogenic group. ( p=0,328 ). The conclusion, atherosclerosis occurred in 4 sampels ( 66% ) of control group and 6 sampels ( 100% ) of atherogenic group. There was no significant difference in coronary artery histopathology Rattus novergicus between the control group with atherogenic group.Keywords : Atherosclerosis, atherogenic diet, coronary artery.

GAMBARAN HISTOPATOLOGI ARTERI KORONARIA TIKUS PUTIH JANTAN GALUR WISTAR SETELAH PEMBERIAN DIET ATEROGENIK SELAMA DELAPAN MINGGU Neneng Mutiara Sari; Enikarmila Asni; Zulkifli Malik
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 1 (2015): Wisuda Februari 2015
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ABSTRACTAtherosclerosis could be induced by feeding rats aterogenik dietcontaining high cholesterol and colic acid. For increasing atherosclerosis processvitamin D3 also given orally. Aim this research has an aims to analyze thedifference of coronary artery histopathologycal image between white rat strainwistar feeding by aterogenic diet and standard diet for 8 weeks. This is anexperimental laboratory research with post test only design. This research usedtwelve rats were segregated into two groups (n=6) labeled ads control; fedstandard diet and atherogenik fed diet ( containing colic acid 0,2%, fat 5%, andyolk 2%) and vitamin D3. The statistic test result do not show a significantdifference of atherogenic score of control group and atherogenic group. As theconclusion, feeding atherogenic diet for 8 weeks can induce the formation ofaccumulation of extracellular lipid in all samples of coronary artery of white rats,atheroma in 3 samples and thrombus 1 samples, while feeding standard diet justso atherosclerosis process on 4 samples, the formation of accumulation ofintracellular lipid in 1 samples and atheroma in 3 sample.Keywords : atherosclerosis, histopathology, atherogenic diet

HUBUNGAN PENGALAMAN BERORGANISASI DENGAN TINGKAT ADVERSITY QUOTIENT (AQ) PADA MAHASISWA ANGKATAN 2012 FAKULTAS KEDOKTERAN UNIVERSITAS RIAU Diva Yurian Dwika; Zulharman "; Muhammad Yulis Hamidy
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 1 (2015): Wisuda Februari 2015
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ABSTRACTAdvance level of Adversity Quotient (AQ) is essential for medical students to gain struggling power in facing the challenges along the study to become a good and successful doctor. Many factors affect people Adversity Quotient (AQ) level, one of them is organization. The level of Adversity Quotient (AQ) depends on life experiences, without exception; organizational experience. The objective of this research was to find out the correlation of organizational experience and Adversity Quotient (AQ) level in medical students year 2012 of university of Riau. This research is an analytical research with cross sectional approach. The subject of the research are medical students year 2012 of university of Riau. Sample of the research consists of 115 medical student which is collected by total sampling technique. The researcher uses a questioner based on organization theories and researches, then adopted Stoltz's theories on Sari's research. The statistic assessment of correlation between organizational experience and Adversity Quotient (AQ) level; uses Spearman's Correlation test. Result of the research shows that there is a significant correlation between organizational experience and Adversity Quotient (AQ) level (r=0,345; p=0,000). The Finding of the research shows that there is a correlation between organizational experience and Adversity Quotient (AQ) level in medical students year 2012 of university of Riau.keyword : organization experience, adversity quotient, medical students

GAMBARAN EFEK SAMPING OBAT ANTI TUBERKULOSIS (OAT) LINI KEDUA PADA PASIEN TUBERCULOSIS-MULTIDRUG RESISTANCE (TB-MDR) DI POLIKLINIK TB-MDR RSUD ARIFIN ACHMAD PROVINSI RIAU Qurratul Aini; Indra Yovi; Muhammad Yulis Hamidy
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 1 (2015): Wisuda Februari 2015
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ABSTRACTMultidrug resistant tuberculosis (MDR-TB) is one of tuberculosis resistance to at leasttwo anti tuberculosis drugs rifampicin and isoniazide. Second line drugs used in MDRTBtreatment had a greater toxicity compared with first line and a lot of adverse event, itcauses patient would have symptoms of side effect during treatment . The purpose of thisresearch had to know adverse event of second line anti-TB drug in MDR-TB patient inMDR-TB polyclinic Arifin Achmad General Hospital of Riau Province. This research wasused as mixed methods with quantitative and qualitative approachment. Adverse eventwas also discussed in qualitative data as a complement. Samples in this research wereobtained by total sampling method as many as 12 MDR-TB patient were diagnosedbetween April 2013 to Juni 2014 . Quantitative study results showed that adverse eventwere experienced by 100% patient. Prevalence of nausea and vomiting was 100%,headache 100%, arthralgia 91,67%, injected location pain 91,67%, peripheralneuropathy 83,33%, depression 83,33%, sleep disturbance 83,33%, allergic reaction75%, anorexia 75%, gastritis 66,67%, hearing distrubance 66,67%, vertigo 58,33%,tendinitis 58,33%, psychosis 50%, visual disturbance 50%, minor electrolite disturbance(hypokalemia) 41,67%, diarrhea 16,67%, severe electrolite disturbance 16,67%, gasterbleeding 8,33%. Qualitative study results showed that patient had difference adverseevent experienced. Management of adverse event by clinical officer in MDR-TBpolyclinic have done their duty based on standart operational procedures.Key word: multidrug resistant tuberculosis (MDR-TB), adverse event of second line anti-TB drug, adverse event of MDR-TB treatment.

HISTOPATOLOGI AORTA TORASIKA Rattus novergicus STRAIN WISTAR JANTAN SETELAH 8 MINGGU PEMBERIAN DIET ATEROGENIK Welinsa, Fatya; Asni, Enikarmila; Malik, Zulkifli
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 1 (2015): Wisuda Februari 2015
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ABSTRACTAtherosclerosis could be induced in animal model (Rattus novergicus) by feeding atherogenic diet consist of standart feed, cholesterol 2 % from yolk, 5 % goat fat, 0,2% cholic acid and induction with vitamin D3. The goal of this research was to analyze histopathological of thoracic aorta on male Rattus novergicus strain wistar after fed atherogenic diet for 8 weeks. This research was an experimental laboratory research with post test only with control design. Twelve male rats were segregated into two groups (n=6) labelled as control fed standart and atherogenic fed group. After 8 weeks thoracic aorta was taken and histological slides were made and colored with hematoxylin eosin and then measured with atherosclerosis score. The result showed that in atherogenic group there are macrophage, foam cell, and intracellular lipid accumulation with 100% percentage, extracellular lipid accumulation 33,33% (for a little extracellular lipid) and 66,67 (a lot of extracellular lipid) while control group there are macrophage, foam cell, and intracellular lipid accumulation with 33,33% percentage. The statistical test result show there is significant difference between control group and atherogenic group (p=0,003). As conclusion, there is significant difference between control group and atherogenic group.Keywords : Atherosclerosis, atherogenic diet, thoracic aorta

KUALITAS VISUM ET REPERTUM PERLUKAAN DI RSUD ROKAN HULU PERIODE 1 JANUARI 2009 - 31 DESEMBER 2013 Ricky Rusydi Satriawan; Dedi Afandi; Suyanto "
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 1 (2015): Wisuda Februari 2015
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ABSTRACTAbout 50%-70% of case that come to a hospital especially to the emergency room are physical trauma or injuries cases. The quality of VeR service directly reflect medicolegal services in hospital because it has broad impact juridical and can determine one’s fate. This research were done to find out the quality of VeR of injury in Rokan Hulu General Hospital during 1 January 2009-31 December 2013. This is a descriptive retrospective research. It used Herkutantos scoring method. The sample was all of population were the VeR data in Rokan Hulu General Hospital during 1 January 2009-31 December 2013 that were complete and has been signed by the doctor who did the examination. It had been gotten 292 VeR reports in Rokan Hulu General Hospital during 1 January 2009-31 December 2013. Injury survivors most cases are in the age group 22-40 years old as many as 177 victims (60,6%). The overview of the living victims were most frequent male was 171 victims ( 58,6%) and the most frequent violence that were experienced by the victims were blunt violence was 267 VeR (91,4%) with the highest age group 22-40 years old. About 80% showed good quality in preliminary unit of VeR, 69,54% showed medium quality in reporting unit and about 49,31% also showed medium quality in inference unit. It can be concluded that quality of VeR reports in Rokan Hulu General Hospital during 1 January 2009-31 December 2013 was 58,82% which was mean it was medium quality.Keywords: Visum et Repertum, injury, the quality of Visum et Repertum of injury

HISTOPATOLOGI AORTA TORASIKA TIKUS PUTIH (Rattus novergicus strain wistar) JANTAN SETELAH PEMBERIAN DIET ATEROGENIK SELAMA 12 MINGGU Sutrisno Tambunan; Enikarmila Asni; Zulkifli Malik
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 1 (2015): Wisuda Februari 2015
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ABSTRACTUnhealthy dietary pattern such as high fat diet and less of physical activity are the determinat of atherosclerosis. Atherosclerosis is a chronic inflammatory disease caused by lipid deposition in arterial wall. Beside the high fat consumption, addition of cholic acid and induction of vitamin D3 may also has role in atherosclerosis. Now, there has been many researches to know the process of the atherosclerosis using rat as animal model. The objective of this research is to know the differences of histopathologic image between thoracic aorta of male white rat (Rattus novergicus strain wistar) fed with standard diet and fed with atherogenic diet for 12 weeks. This research was an experimental laboratory with a post test only design. Twelve male rats were segregated into two groups (n=6) there were labelled as control group fed a standard diet and labelled as atherogenic group fed vitamin D3 and atherogenic diet which contain cholic acid 0,2%, fat 5% and yolk 2%. The experiment was designed for 12 weeks. The parameter used is atherosclerosis lesion score of all groups labelled. The result showed at control group found macrophage, foam cell and intracellular lipid accumulation with 33,33% percentage while atherogenic group found macrophage, foam cell and intracellular lipid accumulation with 100% percentage, extracellular lipid accumulation 33,33% (for a little extracellular lipid), 66,66 (a lot of extracellular lipid) and surface defect with 0,16%. The statistic test result showed the significant difference of atherosclerosis score between control group and atherogenic group (p=0,003). The conclusion of this study there is atherosclerosis process happen in 2 sampel (33,33%) in control group and 6 sampel (100%) in atherogenic group.Keywords : thoracic aorta, atherosclerosis, atherogenic diet, histopathology.

KUALITAS VISUM ET REPERTUM PERLUKAAN DI RSUD SELASIH KABUPATEN PELALAWAN PERIODE 1 JANUARI 2009 - 31 DESEMBER 2013 Taufik Sofistiawan; Dedi Afandi; Laode Burhanuddin Mursali
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 1 (2015): Wisuda Februari 2015
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ABSTRACTGood quality is necessary given the crucial role in the proceedings of a criminal offense. Approximately 50-70 percent of cases that come to the Pelalawan Selasih General Hospital during the Period from January 1 2009-31 December 2013 were an injury cases and require a Visum et Repertum (VeR) and usually requested by investigators as evidence. This study was conducted to obtain a VeR quality at the Pelalawan Selasih General Hospital during the period from January 1 2009-31 December 2013. In order to achieve the intended objectives, retrospective descriptive approach has been used in this observational study. All VeR data that match to the inclusion criteria were sampled as many as 288 injury. Herkutanto scoring method is used to analyze 13 elements. The results of this study showed that 66 percent of survivors (190 cases of injury) is a type of highest violence in the age group 22-40 years male sex. 93.8 percent (270 cases) of the highest hardness is a result of blunt force. Quality introduction Ver were classified Good (76 percent). While the main and Conclusions section of each classified Medium (64 percent and 75 percent). The result of quality VeR in Pelalawan Selasih Gneeral Hospital is 50%. Based on these findings it can be concluded that in general the quality VeR injury in the Pelalawan Selasih General Hospital during the period from January 1 2009-31 December 2013 were categorized Medium.Keywords: Visum et Repertum, injury, quality of VeR of injury

GAMBARAN VISUM ET REPERTUM PERLUKAAN DI RUMAH SAKIT UMUM DAERAH KUANTAN SINGINGI PERIODE 1 JANUARI 2009 - 31 DESEMBER 2013 Wilda Septi Pratiwi; Dedi Afandi; Huriatul Masdar
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 1 (2015): Wisuda Februari 2015
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ABSTRACTVisum et Repertum (VeR) of injury is the type of VeR that most often requested by the investigator to a doctor who works in an emergency room. VeR requested by the investigator is required for law enforcement and justice, so that the quality of VeR which made by a general practitioner affect the clarity of a criminal case and also has a big influence for hospital accreditation. This research were done to figure out VeR of injury in Kuantan Singingi General Hospital during 1st January 2009-31st December 2013. A descriptive retrospective research was designed using Herkutanto’s scoring method. All VeR data in Kuantan Singingi General Hospital during 1st January 2009-31st December 2013 that were complete and has been signed by the doctor who did the examination were counted as samples a hundred fifty four VeR data in Kuantan Singingi General Hospital during 1st January 2009-31st December 2013. Were found injury survivors most cases are in the age group 22-40 years old as many as 78 victims (50,7%), mostly male (61,7%). The most frequent violence that were experienced by the victims were blunt violence was 137 VeR (88,9%) with the highest age group 22-40 years old. The preliminary unit of VeR about 72,3% showed medium quality, the reporting unit about 44,09% showed poor quality and also the inference unit about 40% showed poor quality. It can be concluded that quality of VeR reports in Kuantan Singingi General Hospital during 1st January 2009-31st December 2013 was 43,79% which means poor quality.Keywords: Visum et Repertum, injury, the figure of Visum et Repertum of injury

KUALITAS VISUM ET REPERTUM PERLUKAAN DI RSUD DR.RM.PRATOMO BAGAN SIAPI-API PERIODE 1 JANUARI 2009 - 31 DESEMBER 2013 Ramadhan, Fadlan Tri; Afandi, Dedi; Mursali, Laode Burhanuddin
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 1 (2015): Wisuda Februari 2015
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ABSTRACTThe most frequent Visum et repertum (VeR) requested by investigators is VeR of injury. It is because 50-70% of cases that come to the Emergency Unit are injury cases. A good quality of VeR is required in view of its important role in litigation of a criminal offense. This study was aimed to understand the quality of VeR of injury in Dr.RM.Pratomo General Hospital of Bagan Siapi-api during 1 January 2009-31 December 2013. The research was an observational study using descriptive retrospective design. This study used Herkutanto’s scoring method towards 13 VeR substances. Samples of this study were all data of VeR of injury that had fulfilled inclusion criteria. The total of samples were 48 samples of VeR. This study suggested that the highest number of living victims of injury cases was 29 victims (60,4%) in age group 22-40 years old with the most frequent sex was male as many as 36 victims (75%). The most frequent violence was sharp violence as many as 28 cases (58,3%) with the most frequent age group was 22-40 years old. The quality of VeR in preface was 71% (medium), in body part was 51,56% (medium) and in conclusion was 28,12% (poor). In general, quality of VeR of injury in RSUD Dr.RM.Pratomo General Hospital of Bagan Siapi-api during 1 january 2009-31 december 2013 was 39,46% that could be categorized as poor quality.Keywords: Visum et Repertum, injury, quality of VeR of injury

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