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INDONESIA
Majalah Kedokteran Gigi Indonesia
Published by Universitas Gadjah Mada
ISSN : 24600164     EISSN : 24422576     DOI : https://doi.org/10.22146/majkedgiind.36959
Core Subject : Health,
Dentistry
Arjuna Subject : -
Articles 565 Documents
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Effect of chitosan–hydroxyapatite scaffolds seeded with cryopreserved hADMSCs on bone sialoprotein secretion Kamadjaja, Michael Josef Kridanto; Kuntjoro, Mefina; Pratiwi, Chandrasasi Berlian; Hartanli, Audrey Luisa
Majalah Kedokteran Gigi Indonesia Vol 11, No 3 (2025): December
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.110209

Abstract

Tooth extraction can lead to alveolar bone resorption, requiring regenerative approaches using biomaterial scaffolds combined with stem cells. Chitosan–hydroxyapatite (CS–HA), a well-established scaffold that mimics the composition of human bone, combined with stem cells represents a promising strategy to promote bone formation. This study aimed to evaluate the effect of chitosan–hydroxyapatite (CS-HA) scaffolds seeded with cryopreserved human adipose-derived mesenchymal stem cells (hADMSCs) on bone sialoprotein (BSP) secretion. The hADMSCs used in this study were commercially obtained cryopreserved cells (ATCC® PCS-500-011™) and were characterized by flow cytometry. Scaffolds were fabricated using a freeze-drying method by combining chitosan and hydroxyapatite in a 1 : 1 ratio, followed by freezing at −80 °C. A post-test-only control group design was employed, consisting of 36 samples divided into three groups: positive control (CS-HA + hADMSCs + a-MEM), negative control (hADMSCs + osteogenic medium), and treatment (CS-HA + hADMSCs + osteogenic medium), and BSP levels were subsequently quantified on days 7, 14, 21, and 28 using ELISA. One-way ANOVA demonstrated a significant difference among groups (p = 0.000), with the highest BSP secretion observed in treatment group on day 14 (BSP levels 44.29 ± 2.58), followed by treatment group on day 28 (BSP levels 46.19 ± 7.64).  The significantly elevated BSP secretion in the treatment group on day 14 demonstrates osteoinductive characteristics of the CS-HA scaffold, supporting its potential application in bone tissue engineering and regeneration.
The effect of oil palm empty fruit bunch (Elaeis guineensis Jacq.) fiber addition at various volume fractions on the compressive strength of flowable composite resin Abdullah, Heikal Faried; Aulia, Rahmi Khairani; Fransiska, Aria
Majalah Kedokteran Gigi Indonesia Vol 11, No 3 (2025): December
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.111004

Abstract

Oil palm empty fruit bunch (OPEFB) fibers have emerged as a promising natural alternative to synthetic fibers due to their mechanical strength and biocompatibility, although research on their use as a reinforcing in composite resin remains limited. This study aimed to evaluate the effect of OPEFB fiber incorporation on the compressive strength of flowable composite resin. A true experimental design with a post-test-only control group was employed. The OPEFB fibers underwent chemical and double silane treatments and were randomly oriented prior to incorporation. Fifteen cylindrical specimens (6 mm × 12 mm) were allocated into three groups based on fiber volume fraction (0%, 1%, and 1.5%). Compressive strength was tested using a universal testing machine following ASTM D-695 standards. Data were analyzed using one-way ANOVA (p < 0.05) followed by a post-hoc Least Significant Difference (LSD) test. The mean compressive strength of flowable composite resins at 0%, 1%, and 1.5% OPEFB fiber volume fractions were 261.99 ± 17.64, 301.20 ± 19.26, 368.52 ± 14.90 MPa. One-way ANOVA test showed that the mean compressive strength in the three groups was significantly different (p < 0.05). The post-hoc LSD test showed significant differences (p < 0.05) among all groups. This study concluded that the incorporation of OPEFB fiber can enhance the compressive strength of flowable composite resin, with the highest reinforcement observed at the 1.5% OPEFB fiber volume fraction.
Do different flap designs have negligible impacts on the removal of mandibular third molars? Seta, Astrodita Adya; Arindra, Pingky Krisna; Haryosuwandito, Erdananda
Majalah Kedokteran Gigi Indonesia Vol 11, No 3 (2025): December
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.111285

Abstract

This study aims to evaluate various flap incision techniques utilized in the mandibular third molar removal surgery. A systematic review with a qualitative approach was conducted. Data were obtained from published journals through manual database searches via Scopus, ScienceDirect, and PubMed covering the period from 2000 to 2024, using predetermined keywords related to the topic. The PRISMA statement guidelines were followed, including the use of the official flow chart. Twenty-one journals were identified and analyzed to compare different flap designs in mandibular third molar extraction procedures, focusing on their relationship with wound healing processes and complication rates. Comparative analysis of flap incision techniques was performed through systematic evaluation of multiple journal data. Both envelope and triangular flaps demonstrated comparable healing times in third molar extraction procedures. The envelope flap, while minimally invasive, showed association with dry socket occurrence. The triangular flap provided superior surgical access and demonstrated pain reduction following mandibular third molar surgery. The pedicle flap showed effectiveness in preventing dry socket and alveolar osteitis. In addition, the Lingual-based triangular flap proved superior to buccal-based triangular flap in controlling postoperative pain, swelling, and trismus while reducing overall complications. This analysis demonstrates that flap design selection significantly influences postoperative outcomes in mandibular third molar surgical procedures. Both triangular and envelope flap can be considered for the procedure of mandibular wisdom teeth removal.
Effect of immersion in effervescent granules of watermelon rind (Citrullus lanatus) extract on the surface roughness of artificial teeth Fransiska, Aria; Sabilla, Alifia; Sari, Desy Purnama; Putri, Fidya Meditia
Majalah Kedokteran Gigi Indonesia Vol 11, No 3 (2025): December
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.112104

Abstract

Artificial teeth elements are essential components of removable dentures. Inadequate cleaning can lead to the accumulation of microorganisms, which may cause denture stomatitis. Alkaline peroxide effervescent tablets are commonly used denture cleansers. However, prolonged use may increase the surface roughness of artificial teeth. To address this, an alternative natural-based cleanser has been formulated using red watermelon (Citrullus lanatus) rind extract in effervescent granule form. Effervescent granules of watermelon rind extract have potential as an alternative denture cleanser due to their antibacterial properties. The effervescent reaction helps mechanically remove plaque and debris while inhibiting the growth of microorganisms that cause odor and infection. This formulation is practical, natural, and economical. The study aims to evaluate the effect of immersion in effervescent granules containing watermelon rind extract on the surface roughness of artificial teeth. This was a laboratory experimental study using acrylic resin-based artificial teeth. Samples were divided into three treatment groups: aquadest, alkaline peroxide effervescent solution, and watermelon rind effervescent granule solution (n = 5). Surface roughness was measured using a Surface Roughness Tester, and data were analyzed with the Kruskal–Wallis test (p < 0.05). The mean surface roughness values after immersion in aquadest, alkaline peroxide solution, and watermelon rind effervescent granules were 0.140 ± 0.026 µm, 0.616 ± 0.213 µm, and 0.670 ± 0.041 µm, respectively. The findings demonstrate that immersion in effervescent granules containing watermelon rind extract significantly increases the surface roughness of artificial teeth. Further formulation development is recommended to optimize its potential as a natural denture cleanser.
Effect of pineapple core extract on growth and saliva stimulation in Stunted Rats Abdat, Munifah; Fitri, Maida; Putri, Citra Feriana
Majalah Kedokteran Gigi Indonesia Vol 11, No 3 (2025): December
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.113844

Abstract

Stunting refers to a condition of short stature in toddlers due to delayed growth from the prenatal period until the age of 24 months. Chronic malnutrition in stunted toddlers leads to protein deficiency; therefore, active substances are needed for maximum protein absorption. Pineapple core (Ananas comosus) contains bromelainenzymes and citric acid, whichcan enhance protein absorption in conditions of chronic malnutrition and increase saliva flow rate.This study aims to investigate the effect of pineapple core extract on growth parameters and saliva flow rate in stunted Wistar rats. This study involved 16 male Wistar rats, which were divided into four groups: a negative control group (no treatment), a treatment group (75% pineapple core extract), a positive control group 1 (FeSo4 supplements), and positive control group 2 (pilocarpine hydrochloride). Growth parameters and saliva flow rate were measured before and after pineapple core extract treatment. The research results were analyzed using one-way ANOVA followed by Tukeys test, which showed a significant difference between the treatment group and the other groups in body weight (p = 0.037), body length (p = 0.028), tail length (p = 0.003), and saliva flow rate (p = 0.000). Administration of 75% pineapple core extract resulted in increased growth parameters (body weight, body length, and tail length) and saliva flow rate in stunted rats.

Page 57 of 57 | Total Record : 565

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