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INDONESIA
Journal of Agromedicine and Medical Sciences
Published by Universitas Jember
ISSN : 24609048     EISSN : 27145654     DOI : -
Core Subject : Health,
Health Professions
Jurnal Agromedicine and Medical Sciences (AMS) adalah jurnal berkala empat bulan (Februari, Juni dan Oktober) yang berisi berbagai artikel dalam bentuk penelitian, tinjauan sistematis dan laporan kasus dalam bidang kedokteran dengan fokus pada ilmu-ilmu kedokteran dasar, kedokteran klinis dan agromedis.
Arjuna Subject : -
Articles 305 Documents
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Mortality Rates Of Adult Pulmonary Tuberculosis With Malnutrition: A Case Report And Comprehensive Literature Review Muhammad Ilham Dhiya Rakasiwi; Astrid Mariam Khairani Siregar; Brayanna Infinita Laviashna Saputro; Fathiyah Isbaniah; Lily Indriani Octovia
Journal of Agromedicine and Medical Sciences Vol 9 No 3 (2023)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v9i3.41523

Abstract

Tuberculosis (TB) and malnutrition are still major public health problems in the world. These two clinical conditions can occur simultaneously and create a vicious cycle that worsens TB infection or nutritional status. This case report aims to examine the relationship between low nutritional status (malnutrition) of patients and death due to pulmonary TB. A 31 year old woman came to the pulmonary clinic of a tertiary hospital in Jakarta for her third month of drug-sensitive anti-TB drug (OAT) treatment control. Three months earlier, the patient underwent a rapid diagnostic test (RDT) to determine OAT resistance. The conclusion of her anthropometric examination was body mass index (BMI) of 15.6 kg/m2. Before being diagnosed with pulmonary TB, she always had difficulty gaining weight. During the course of disease, her weight decreased by 5 kg per month. After undergoing treatment for 6 months, the patient was declared complete after 6 months of therapy, without any improvement in nutritional status. At 1 year follow-up, the patient experienced a relapse of pulmonary TB with a BMI of 13.2 kg/m2. She died 2 months after diagnosis of relapse TB. Improvement in clinical complaints and conversion to bacteriological examination are indications of successful therapy, including improvement in nutritional status. To analyze the relationship between malnutrition and pulmonary TB and death, the authors conducted a comprehensive literature search in the journal databases PubMed, Cochrane, and Scopus, followed by analysis according to the PRISMA 2020 flowchart, for a prognostic cohort study of cases of death in pulmonary TB patients with malnutrition. There is a relationship between BMI and the risk of death in TB patients. Anthropometric measurements, especially BMI, need to be carried out during every physical examination of pulmonary TB cases. Keywords: Body mass index; Malnutrition; Mortality; Tuberculosis
Determination Of Total Flavonoid Content Of Yellow Wood (Arcangelisia Flava (L.) Merr) Extract And Antibacterial Activity Against Staphylococcus aureus Maryanti Yuza; Ridwanto Ridwanto; Zulmai Rani
Journal of Agromedicine and Medical Sciences Vol 9 No 3 (2023)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v9i3.42614

Abstract

Yellow wood (Arcangelisia flava) is a medicinal plant that has received little attention. Merr and (L.). Yellow wood has antibacterial, antioxidant, anti-hyperlipidemic, and anti-cancer properties. Furthermore, yellow wood is known to contain a range of flavonoid compounds, such as hydroxylarcangelicin, which has broad antibacterial activity. The purpose of this research is to investigate the total flavonoid content of yellowwood extract as well as its antibacterial activity against Staphylococcus aureus bacteria. The manufacturing of methanol extract, characterization of simplisia, phytochemical screening, and determination of the total flavonoid levels of the yellow wood methanol extract by a visible spectroscopic approach were all part of this stage of research. Next, use chloramphenicol as a positive control and dimethyl sulfoxide (DMSO) as a negative control to test antibacterial activity against Staphylococcus aureus. The results of this study can be concluded to show that the total flavonoid levels in the methanol extract of yellow wood at a metanol concentration of 80% were 228,314 ± 5,4171 mg QE/g. At a 90% concentration of 245.993 ± 6.7626 mg QE/g and a 100% concentration of 265.953 3.0853 mg QE/g. Keywords: Yellow wood; Flavonoids; Spektrofotometri Visible; Stphylococcus aureus;
Cover AMS Vol. 9 No. 3 (2023) Zahrah Febianti
Journal of Agromedicine and Medical Sciences Vol 9 No 3 (2023)
Publisher : Faculty of Medicine, Universitas Jember

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Abstract

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Management of General Anesthesia in Difficult Airway: A Case Report Taufiq Gemawan; Adelia Handoko; Muhammad Irsyad Amien; Nurrul Izza Misturiansyah; Muhamad Rizal Hadi Pratama
Journal of Agromedicine and Medical Sciences Vol 9 No 3 (2023)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v9i3.41778

Abstract

When dealing with clinical disorders known as difficult airways, airway management during general anesthesia still presents challenges. A cross-sectional study done in Indonesia in 2016 found that 28 out of 250 patients receiving general anesthesia had respiratory problems. The existing algorithm must be properly and effectively managed in order to resolve this issue. This case report discusses a 14-month-old pediatric patient with right preauricular lymphoma who will undergo tumor biopsy surgery using general anesthesia. The size of the tumor mass that has grown and covered the patient's airway makes it difficult to manage the airway during general anesthesia, making intubation impossible. To overcome this, bagging was carried out by improvising the technique of reversing the position of the mask cover on the patient during the operation. The patient can be saved and allowed to go home after treatment. Appropriate management during perioperative especially related to airway management will produce good results for patient health and safety. With this case report, hopefully it can add knowledge and an alternative ventilation technique if you encounter a similar case. Keywords: difficult airway, general anesthesia, lymphoma preauricular
Factors Affecting Patterns of Fast Food Consumption in Students of Medical Study Program Faculty of Medicine Tanjungpura University Carla Jean Marshellina; Agustina Arundina Triharja Tejoyuwono; Abror Irsan
Journal of Agromedicine and Medical Sciences Vol 9 No 3 (2023)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v9i3.41505

Abstract

Medical students who are in their late teens and are affected by high stress due to academic loads experience changes in nutritional intake behavior, namely changes in eating patterns with a tendency to consume fast food (fast food). The purpose of this study was to determine the factors that influence fast food consumption patterns in students of the Medical Study Program, Faculty of Medicine, Tanjungpura University. This study uses a type of observational analytic research with a cross-sectional design. This study used data on weight and height measurements, a 3x24-hour Food Record, and a questionnaire on 46 students of the Medical Study Program class of 2022. The results showed low consumption of calories, protein and carbohydrates, and high consumption of fat. The overall average intake of energy, fat and carbohydrates is normal, while protein intake is low. There is no effect of all variables on consumption of energy, protein, fat, carbohydrates, and nutritional status. However, action on fast food has a significant effect on energy consumption. Students often consume fast food which is processed by frying process. Low protein intake and high fat consumption indicate the need for education for food selection in reducing the negative impact on the health of medical students. Keywords: Fast food, medical students, consumption patterns, factors
The Correlation between Thrombocyte, Hematocrit, and Leukocyte Count with Length of Hospitalization in Pediatric Patient with Dengue Hemorrhagic Fever (DHF) Muhammad Fikri; Muhammad Ali Shodikin; Dwita Aryadina Rachmawati
Journal of Agromedicine and Medical Sciences Vol 10 No 1 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i1.40074

Abstract

Dengue Hemorrhagic Fever (DHF) is a disease caused by dengue virus with mosquito vectors. Supporting examinations to determine the course of DHF include platelet counts, hematocrit values, and leukocyte counts. Length of hospitalization is the number of days when the patient receives treatment in the hospital, calculated when recorded as an inpatient until discharge from the hospital. This type of research is an analytic observational study with a cross sectional research design. Cases of pediatric DHF at Bina Sehat Hospital Jember for the period 2020-2022 totaled 296 patients. Data were obtained using medical records. Of the 296 cases of pediatric DHF, samples were then taken by purposive sampling according to the researcher's criteria until 44 samples were obtained. The data were then analyzed using Rank Spearman. The results of the data analysis showed that there was a strong opposite relationship (p = 0.000; r = -0.562) between platelet count and length of hospitalization, a strong unidirectional relationship (p = 0.001; r = 0.495) between hematocrit value and length of hospitalization, and a strong opposite relationship (p = 0.005; r = -0.415) between leukocyte count and length of hospitalization. Suggestions for future research are to use other variables such as nutritional status, medical history, and other laboratory examinations. Keywords: Dengue Hemorrhagic Fever; Length of Hospitalization; Thrombocyte; Hematocrit; Leukocyte
In Silico Test Potential of Bromelain and Actinidin Enzymes as Proteolytic againts Cataract-forming Proteins Elok Tiara Pratmawati; Nugraha Wahyu Cahyana; Zahrah Febianti
Journal of Agromedicine and Medical Sciences Vol 10 No 2 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i2.25496

Abstract

A cataract is the development of an opacity within the lens that can cause blindness. Cataracts are caused by the aggregation of crystallin proteins, which are water-soluble proteins that make up 80% of all lens proteins. Crystallin protein aggregation can occur due to several mechanisms such as the formation of amyloid fibrils (associated with senile cataract) and P23T mutations (associated with congenital cataracts). Currently, surgery is the only cataract treatment available. Although it is the best treatment, surgery requires high cost and is not free from complications. Therefore, alternative treatments for cataracts are needed, such as the use of natural ingredients that have proteolytic properties. Pineapple contains bromelain and kiwi contains actinidin. Both enzymes are protease which destabilize and inhibit the formation of aggregates. So that those enzymes can potentially lyse the protein causes cataracts. To prove the potency of the enzymes, we consucted an insilico study using Cluspro docking online program. We investigate the binding energy of each enzymes with the amyloid fibril and P23T mutation. The results of Cluspro docking between Bromelain Enzyme and Actinidin Enzyme with P23T mutation protein respectively are -696.2 Kcal/mol and -750.8 Kcal/mol. The results of Cluspro docking between Bromelain Enzyme and Actinidin Enzyme with amyloid protein are -696.2 Kcal/mol and -750.8 Kcal/mol respectively. Therefore, bromelain enzyme had a better ability to bind to amyloid protein, while the actinidin enzyme had a better ability to bind to the P23T D-crystallin mutation protein. Keywords: ClusPro, Molecular Docking, Bromelain, Actinidin, Cataract, SwissModel
Cover AMS Vol. 10 No. 1 (2024) Zahrah Febianti
Journal of Agromedicine and Medical Sciences Vol 10 No 1 (2024)
Publisher : Faculty of Medicine, Universitas Jember

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Abstract

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Profiling and In Silico Study of Carica papaya Extract on Appetite Regulation Isnaini Isnaini; Dwi Setyohadi; Wahyuni Wahyuni; Risma Yulfa Riyani; Khansa Khafiyya 'Ibadurrahman; Andifa Anugerah Putra
Journal of Agromedicine and Medical Sciences Vol 10 No 1 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i1.43095

Abstract

Carica papaya is one of the plants known to increase appetite. 15% papaya leaf solution can increase appetite, but if given in 20% solution there is a weight loss effect. Papaya leaves contain papain, carpaine and various other compounds. The mechanisms that affect appetite regulation involve ghrelin, leptin, ARC, IL-1β and NPY. This study aims to determine the compound profile contained in papaya leaf extract and its effect on appetite regulation that has been analyzed with in silico methods. The method of determining the profiling of papaya leaf extract compounds using UPLC / MS and analyzed using watermaslinx, in silico analysis used molecular docking methods using PatchDock. The results of this study are the most compounds found in papaya leaf extract (Carica papaya) is carpaine with a concentration of 50.33%. then, carpaine compounds will be analyzed using in silico method to see its effect on appetite regulation. The results of in silico analysis showed that carpaine has a strong potential to interact with NPY, IL-1 Beta, and Leptin, forming a stable complex. The strongest bond occurs between carpaine and leptin, so it can be predicted that papaya leaf extract, especially carpaine, causes a feeling of fullness. Keywords: Carpaine; leptin, ghrelin, molecular docking, appetite
Fibroma of the Vastus Lateralis Tendon Sheath in the Thigh of the 58-year-old Female: A Rare Case Report Heni Fatmawati; Hantonius Hantonius; Antonius Dwi Saputra; Candra Bumi
Journal of Agromedicine and Medical Sciences Vol 10 No 2 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i2.45329

Abstract

Background: Fibroma of the tendon sheath (FTS) is a rare slow-growing noncancerous fibrous tumor that is usually small, painless and involves the upper extremity tendons in young adult males. FTS of the lower extremity is an unusual and underreported variety that poses a diagnostic preoperative challenge. Case description: We report an atypical case of a large fibroma of the vastus lateralis tendon in a 58-year-old female presented with a painful lump in her right thigh within the past six months. Physical examination showed a hard firm mass approximately 6 cm in diameter palpated in the anterior of the lower thigh. The mass was smooth, mobile, solid, and had well-defined borders. There was no adhesion to the skin, redness, or tenderness. MRI showed a 4,2 x 5,8 x 6,2 cm tumor with isointense signals on T1-weighted images (T1WI), heterogeneous hypointense signals on T2-weighted images (T2WI), and hyperintense signals on FatSat images. Biopsy revealed no malignant findings and the tumor had been surgically resected. Imaging studies for FTS have rarely been described, T1WI often show a low signal mass, with slight isointense to hypointense to the muscle. The T2WI’s appearance of FTS is more variable. Conclusion: In spite of rarity, FTS must still be included as a differential diagnosis of a thigh mass especially if the mass is painful and benign-appearing on physical exam and radiology.

Page 26 of 31 | Total Record : 305

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